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Abnormal femoral head morphology

MedGen UID:
871147
•Concept ID:
C4025620
•
Anatomical Abnormality
Synonym: Abnormality of the femoral head
 
HPO: HP:0003368

Definition

An abnormality of the femoral head. [from HPO]

Professional guidelines

PubMed

Osteonecrosis of the femoral head: evaluation and treatment.
Zalavras CG, Lieberman JR
J Am Acad Orthop Surg 2014 Jul;22(7):455-64. doi: 10.5435/JAAOS-22-07-455. PMID: 24966252
The diagnosis and management of femoro-acetabular impingement.
Macfarlane RJ, Haddad FS
Ann R Coll Surg Engl 2010 Jul;92(5):363-7. doi: 10.1308/003588410X12699663903791. PMID: 20626968Free PMC Article
Treatment positions for congenital dysplasia of the hip.
Ogden JA
J Pediatr 1975 May;86(5):732-4. doi: 10.1016/s0022-3476(75)80358-1. PMID: 1133654

Recent clinical studies

Etiology

Developmental dysplasia of the hip.
Zhang S, Doudoulakis KJ, Khurwal A, Sarraf KM
Br J Hosp Med (Lond) 2020 Jul 2;81(7):1-8. Epub 2020 Jul 6 doi: 10.12968/hmed.2020.0223. PMID: 32730146
The management of residual acetabular dysplasia: updates and controversies.
Mansour E, Eid R, Romanos E, Ghanem I
J Pediatr Orthop B 2017 Jul;26(4):344-349. doi: 10.1097/BPB.0000000000000358. PMID: 27379671
Developmental dysplasia of the hip: nursing implications and anticipatory guidance for parents.
Hart ES, Albright MB, Rebello GN, Grottkau BE
Orthop Nurs 2006 Mar-Apr;25(2):100-9; quiz 110-1. doi: 10.1097/00006416-200603000-00005. PMID: 16572026
Developmental dysplasia of the hip from six months to four years of age.
Vitale MG, Skaggs DL
J Am Acad Orthop Surg 2001 Nov-Dec;9(6):401-11. doi: 10.5435/00124635-200111000-00005. PMID: 11730331
Femoral morphometry and anterior knee pain.
Eckhoff DG, Montgomery WK, Kilcoyne RF, Stamm ER
Clin Orthop Relat Res 1994 May;(302):64-8. PMID: 8168324

Diagnosis

Developmental dysplasia of the hip.
Zhang S, Doudoulakis KJ, Khurwal A, Sarraf KM
Br J Hosp Med (Lond) 2020 Jul 2;81(7):1-8. Epub 2020 Jul 6 doi: 10.12968/hmed.2020.0223. PMID: 32730146
Postoperative imaging in femoroacetabular impingement.
Dietrich TJ, Dora C, Pfirrmann CW
Semin Musculoskelet Radiol 2013 Jul;17(3):272-8. Epub 2013 Jun 20 doi: 10.1055/s-0033-1348093. PMID: 23787981
Femoroacetabular impingement.
Kassarjian A, Brisson M, Palmer WE
Eur J Radiol 2007 Jul;63(1):29-35. Epub 2007 May 7 doi: 10.1016/j.ejrad.2007.03.020. PMID: 17485190
Anterior femoroacetabular impingement.
Laude F, Boyer T, Nogier A
Joint Bone Spine 2007 Mar;74(2):127-32. Epub 2007 Feb 5 doi: 10.1016/j.jbspin.2007.01.001. PMID: 17337228
Femoroacetabular impingement.
Kassarjian A, Cerezal L, Llopis E
Top Magn Reson Imaging 2006 Oct;17(5):337-45. doi: 10.1097/rmr.0b013e3180421caf. PMID: 17414995

Therapy

Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts.
Chen K, Liu Y, He J, Pavlos N, Wang C, Kenny J, Yuan J, Zhang Q, Xu J, He W
Int J Biol Sci 2020;16(11):1888-1900. Epub 2020 Apr 6 doi: 10.7150/ijbs.40917. PMID: 32398957Free PMC Article
Enzyme replacement therapy in mice lacking arylsulfatase B targets bone-remodeling cells, but not chondrocytes.
Hendrickx G, Danyukova T, Baranowsky A, Rolvien T, Angermann A, Schweizer M, Keller J, Schröder J, Meyer-Schwesinger C, Muschol N, Paganini C, Rossi A, Amling M, Pohl S, Schinke T
Hum Mol Genet 2020 Mar 27;29(5):803-816. doi: 10.1093/hmg/ddaa006. PMID: 31943020Free PMC Article
Postoperative imaging in femoroacetabular impingement.
Dietrich TJ, Dora C, Pfirrmann CW
Semin Musculoskelet Radiol 2013 Jul;17(3):272-8. Epub 2013 Jun 20 doi: 10.1055/s-0033-1348093. PMID: 23787981
Serum calcium-decreasing factor, caldecrin, ameliorates muscular dystrophy in dy/dy mice.
Tomomura M, Fujii T, Sakagami H, Tomomura A
In Vivo 2011 Mar-Apr;25(2):157-63. PMID: 21471529
Osteonecrosis of the femoral head: a prospective study with MRI.
Sakamoto M, Shimizu K, Iida S, Akita T, Moriya H, Nawata Y
J Bone Joint Surg Br 1997 Mar;79(2):213-9. doi: 10.1302/0301-620x.79b2.7179. PMID: 9119845

Prognosis

DeepGA for automatically estimating fetal gestational age through ultrasound imaging.
Dan T, Chen X, He M, Guo H, He X, Chen J, Xian J, Hu Y, Zhang B, Wang N, Xie H, Cai H
Artif Intell Med 2023 Jan;135:102453. Epub 2022 Nov 17 doi: 10.1016/j.artmed.2022.102453. PMID: 36628790
The management of residual acetabular dysplasia: updates and controversies.
Mansour E, Eid R, Romanos E, Ghanem I
J Pediatr Orthop B 2017 Jul;26(4):344-349. doi: 10.1097/BPB.0000000000000358. PMID: 27379671
MRI findings in residual hip dysplasia.
Wakabayashi K, Wada I, Horiuchi O, Mizutani J, Tsuchiya D, Otsuka T
J Pediatr Orthop 2011 Jun;31(4):381-7. doi: 10.1097/BPO.0b013e31821a556e. PMID: 21572275
Developmental dysplasia of the hip: nursing implications and anticipatory guidance for parents.
Hart ES, Albright MB, Rebello GN, Grottkau BE
Orthop Nurs 2006 Mar-Apr;25(2):100-9; quiz 110-1. doi: 10.1097/00006416-200603000-00005. PMID: 16572026
Developmental dysplasia of the hip from six months to four years of age.
Vitale MG, Skaggs DL
J Am Acad Orthop Surg 2001 Nov-Dec;9(6):401-11. doi: 10.5435/00124635-200111000-00005. PMID: 11730331

Clinical prediction guides

Steroid-induced osteonecrosis of the femoral head reveals enhanced reactive oxygen species and hyperactive osteoclasts.
Chen K, Liu Y, He J, Pavlos N, Wang C, Kenny J, Yuan J, Zhang Q, Xu J, He W
Int J Biol Sci 2020;16(11):1888-1900. Epub 2020 Apr 6 doi: 10.7150/ijbs.40917. PMID: 32398957Free PMC Article
Postoperative imaging in femoroacetabular impingement.
Dietrich TJ, Dora C, Pfirrmann CW
Semin Musculoskelet Radiol 2013 Jul;17(3):272-8. Epub 2013 Jun 20 doi: 10.1055/s-0033-1348093. PMID: 23787981
Craniometaphyseal dysplasia.
Kim YH, Roh DH, Choi BY, Oh SH
Acta Otolaryngol 2005 Jul;125(7):797-800. doi: 10.1080/00016480510028474. PMID: 16012045
Adult osteosclerosis.
Evans RA, Hughes WG, Dunstan CR, Lennon WP, Kohan L, Hills E, Wong SY
Metab Bone Dis Relat Res 1983-1984;5(3):111-7. doi: 10.1016/0221-8747(83)90011-5. PMID: 6676625
Coxa magna.
Powers JA, Bach PJ
South Med J 1977 Nov;70(11):1297-9. doi: 10.1097/00007611-197711000-00014. PMID: 918696

Recent systematic reviews

Research progress in the pathogenesis of hormone-induced femoral head necrosis based on microvessels: a systematic review.
Ma T, Wang Y, Ma J, Cui H, Feng X, Ma X
J Orthop Surg Res 2024 Apr 26;19(1):265. doi: 10.1186/s13018-024-04748-2. PMID: 38671500Free PMC Article
Earlier detection of hypochondroplasia: A large single-center UK case series and systematic review.
Sabir AH, Sheikh J, Singh A, Morley E, Cocca A, Cheung MS, Irving M
Am J Med Genet A 2021 Jan;185(1):73-82. Epub 2020 Oct 14 doi: 10.1002/ajmg.a.61912. PMID: 33051983
Finite element analysis of mechanical behavior of human dysplastic hip joints: a systematic review.
Vafaeian B, Zonoobi D, Mabee M, Hareendranathan AR, El-Rich M, Adeeb S, Jaremko JL
Osteoarthritis Cartilage 2017 Apr;25(4):438-447. Epub 2016 Nov 9 doi: 10.1016/j.joca.2016.10.023. PMID: 27836678
Is Age or Surgical Approach Associated With Osteonecrosis in Patients With Developmental Dysplasia of the Hip? A Meta-analysis.
Novais EN, Hill MK, Carry PM, Heyn PC
Clin Orthop Relat Res 2016 May;474(5):1166-77. doi: 10.1007/s11999-015-4590-5. PMID: 26472583Free PMC Article
What Is the Association Between Sports Participation and the Development of Proximal Femoral Cam Deformity? A Systematic Review and Meta-analysis.
Nepple JJ, Vigdorchik JM, Clohisy JC
Am J Sports Med 2015 Nov;43(11):2833-40. Epub 2015 Jan 13 doi: 10.1177/0363546514563909. PMID: 25587186

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