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Enhanced neurotoxicity of vincristine

MedGen UID:
871184
•Concept ID:
C4025661
•
Finding
HPO: HP:0003009

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVEnhanced neurotoxicity of vincristine

Professional guidelines

PubMed

Treatment of advanced non-Hodgkin's lymphoma with vincristine infusion.
Jackson DV Jr, Paschold EH, Spurr CL, Muss HB, Richards F 2nd, Cooper MR, White DR, Stuart JJ, Hopkins JO, Rich R Jr
Cancer 1984 Jun 15;53(12):2601-6. doi: 10.1002/1097-0142(19840615)53:12<2601::aid-cncr2820531205>3.0.co;2-d. PMID: 6722721

Recent clinical studies

Etiology

Vincristine-induced seizure potentiated by itraconazole following RCHOP chemotherapy for diffuse large B-cell lymphoma.
Foroughinia F, Baniasadi S, Seifi S, Fahimi F
Curr Drug Saf 2012 Nov 1;7(5):372-4. doi: 10.2174/157488612805076633. PMID: 23320431
Effect of azole antifungal therapy on vincristine toxicity in childhood acute lymphoblastic leukaemia.
van Schie RM, Brüggemann RJ, Hoogerbrugge PM, te Loo DM
J Antimicrob Chemother 2011 Aug;66(8):1853-6. Epub 2011 Jun 7 doi: 10.1093/jac/dkr223. PMID: 21652620
Risk of azole-enhanced vincristine neurotoxicity in pediatric patients with hematological malignancies: old problem - new dilemma.
Pana ZD, Roilides E
Pediatr Blood Cancer 2011 Jul 15;57(1):30-5. Epub 2011 Jan 24 doi: 10.1002/pbc.22972. PMID: 21265011
Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study.
Lai R, Abrey LE, Rosenblum MK, DeAngelis LM
Neurology 2004 Feb 10;62(3):451-6. doi: 10.1212/01.wnl.0000106941.51340.a2. PMID: 14872029
Treatment for primary CNS lymphoma: the next step.
Abrey LE, Yahalom J, DeAngelis LM
J Clin Oncol 2000 Sep;18(17):3144-50. doi: 10.1200/JCO.2000.18.17.3144. PMID: 10963643

Diagnosis

Treating relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia: liposome-encapsulated vincristine.
Davis T, Farag SS
Int J Nanomedicine 2013;8:3479-88. Epub 2013 Sep 16 doi: 10.2147/IJN.S47037. PMID: 24072970Free PMC Article
Itraconazole-related increased vincristine neurotoxicity: case report and review of literature.
Bermúdez M, Fuster JL, Llinares E, Galera A, Gonzalez C
J Pediatr Hematol Oncol 2005 Jul;27(7):389-92. doi: 10.1097/01.mph.0000172751.06286.5b. PMID: 16012330
Increasing the dosage of vincristine: a clinical and pharmacokinetic study of continuous-infusion vincristine in children with central nervous system tumors.
Kellie SJ, Koopmans P, Earl J, Nath C, Roebuck D, Uges DR, De Graaf SS
Cancer 2004 Jun 15;100(12):2637-43. doi: 10.1002/cncr.20220. PMID: 15197807
Low-grade gliomas.
Stieber VW
Curr Treat Options Oncol 2001 Dec;2(6):495-506. doi: 10.1007/s11864-001-0071-z. PMID: 12057095
Enhanced vincristine neurotoxicity from drug interactions: case report and review of literature.
Sathiapalan RK, El-Solh H
Pediatr Hematol Oncol 2001 Dec;18(8):543-6. doi: 10.1080/088800101753328529. PMID: 11764105

Therapy

Treating relapsed or refractory Philadelphia chromosome-negative acute lymphoblastic leukemia: liposome-encapsulated vincristine.
Davis T, Farag SS
Int J Nanomedicine 2013;8:3479-88. Epub 2013 Sep 16 doi: 10.2147/IJN.S47037. PMID: 24072970Free PMC Article
Effect of azole antifungal therapy on vincristine toxicity in childhood acute lymphoblastic leukaemia.
van Schie RM, Brüggemann RJ, Hoogerbrugge PM, te Loo DM
J Antimicrob Chemother 2011 Aug;66(8):1853-6. Epub 2011 Jun 7 doi: 10.1093/jac/dkr223. PMID: 21652620
Risk of azole-enhanced vincristine neurotoxicity in pediatric patients with hematological malignancies: old problem - new dilemma.
Pana ZD, Roilides E
Pediatr Blood Cancer 2011 Jul 15;57(1):30-5. Epub 2011 Jan 24 doi: 10.1002/pbc.22972. PMID: 21265011
Vincristine: Can its therapeutic index be enhanced?
Moore A, Pinkerton R
Pediatr Blood Cancer 2009 Dec 15;53(7):1180-7. doi: 10.1002/pbc.22161. PMID: 19588521
Low-grade gliomas.
Stieber VW
Curr Treat Options Oncol 2001 Dec;2(6):495-506. doi: 10.1007/s11864-001-0071-z. PMID: 12057095

Prognosis

Pharmacokinetics and pharmacodynamics of vincristine sulfate liposome injection (VSLI) in adults with acute lymphoblastic leukemia.
Silverman JA, Reynolds L, Deitcher SR
J Clin Pharmacol 2013 Nov;53(11):1139-45. Epub 2013 Aug 17 doi: 10.1002/jcph.155. PMID: 23907766
Increasing the dosage of vincristine: a clinical and pharmacokinetic study of continuous-infusion vincristine in children with central nervous system tumors.
Kellie SJ, Koopmans P, Earl J, Nath C, Roebuck D, Uges DR, De Graaf SS
Cancer 2004 Jun 15;100(12):2637-43. doi: 10.1002/cncr.20220. PMID: 15197807
Treatment-induced leukoencephalopathy in primary CNS lymphoma: a clinical and autopsy study.
Lai R, Abrey LE, Rosenblum MK, DeAngelis LM
Neurology 2004 Feb 10;62(3):451-6. doi: 10.1212/01.wnl.0000106941.51340.a2. PMID: 14872029
Low-grade gliomas.
Stieber VW
Curr Treat Options Oncol 2001 Dec;2(6):495-506. doi: 10.1007/s11864-001-0071-z. PMID: 12057095
Accelerated chemotherapy in the treatment of urothelial cancer.
Huddart RA, Lau FN, Guerrero-Urbano T, Jay G, Norman A, Horwich A, Dearnaley DP
Clin Oncol (R Coll Radiol) 2001;13(4):279-83. doi: 10.1053/clon.2001.9269. PMID: 11554626

Clinical prediction guides

The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells.
Tu HJ, Lin YJ, Chao MW, Sung TY, Wu YW, Chen YY, Lin MH, Liou JP, Pan SL, Yang CR
Clin Epigenetics 2018 Dec 29;10(1):162. doi: 10.1186/s13148-018-0595-8. PMID: 30594243Free PMC Article
Pharmacokinetics and pharmacodynamics of vincristine sulfate liposome injection (VSLI) in adults with acute lymphoblastic leukemia.
Silverman JA, Reynolds L, Deitcher SR
J Clin Pharmacol 2013 Nov;53(11):1139-45. Epub 2013 Aug 17 doi: 10.1002/jcph.155. PMID: 23907766
Low-grade gliomas.
Stieber VW
Curr Treat Options Oncol 2001 Dec;2(6):495-506. doi: 10.1007/s11864-001-0071-z. PMID: 12057095
Enhanced vincristine neurotoxicity from drug interactions: case report and review of literature.
Sathiapalan RK, El-Solh H
Pediatr Hematol Oncol 2001 Dec;18(8):543-6. doi: 10.1080/088800101753328529. PMID: 11764105
Potentiation of vincristine toxicity by itraconazole in children with lymphoid malignancies.
Kamaluddin M, McNally P, Breatnach F, O'Marcaigh A, Webb D, O'Dell E, Scanlon P, Butler K, O'Meara A
Acta Paediatr 2001 Oct;90(10):1204-7. doi: 10.1080/080352501317061675. PMID: 11697438

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