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Abnormal skull base morphology

MedGen UID:
871209
Concept ID:
C4025688
Anatomical Abnormality
Synonyms: Abnormality of cranial base; Abnormality of the skull base
 
HPO: HP:0002693

Definition

An abnormality of the base of the skull, which forms the floor of the cranial cavity and separates the brain from other facial structures. The skull base is made up of five bones [from HPO]

Professional guidelines

PubMed

Rutkowski MJ, Jian B, Lawton MT
Handb Clin Neurol 2017;143:107-116. doi: 10.1016/B978-0-444-63640-9.00010-2. PMID: 28552132
Jindal G, Miller T, Raghavan P, Gandhi D
Radiol Clin North Am 2017 Jan;55(1):151-166. Epub 2016 Oct 25 doi: 10.1016/j.rcl.2016.08.003. PMID: 27890183
Poretti A, Ashmawy R, Garzon-Muvdi T, Jallo GI, Huisman TA, Raybaud C
Neuropediatrics 2016 Oct;47(5):293-307. Epub 2016 Jun 23 doi: 10.1055/s-0036-1584563. PMID: 27337547

Recent clinical studies

Etiology

Maramattom BV, Ram SA, Viswam V, Nair S
Neurol India 2022 Sep-Oct;70(5):1911-1919. doi: 10.4103/0028-3886.359218. PMID: 36352587
Whitehead MT, Barkovich MJ, Sidpra J, Alves CA, Mirsky DM, Öztekin Ö, Bhattacharya D, Lucato LT, Sudhakar S, Taranath A, Andronikou S, Prabhu SP, Aldinger KA, Haldipur P, Millen KJ, Barkovich AJ, Boltshauser E, Dobyns WB, Mankad K
AJNR Am J Neuroradiol 2022 Oct;43(10):1488-1493. Epub 2022 Sep 22 doi: 10.3174/ajnr.A7659. PMID: 36137655Free PMC Article
Schreiber A, Ravanelli M, Rampinelli V, Ferrari M, Vural A, Mattavelli D, Mataj E, Mazza V, Zorza I, Bonù ML, Signorini L, Chiari E, Sorrentino T, Doglietto F, Farina D, Maroldi R, Nicolai P
Neurosurg Rev 2021 Feb;44(1):555-569. Epub 2020 Feb 8 doi: 10.1007/s10143-020-01254-x. PMID: 32036506
Rajan R, Tunkel DE
Clin Perinatol 2018 Dec;45(4):751-767. Epub 2018 Sep 18 doi: 10.1016/j.clp.2018.07.011. PMID: 30396416
Shen W, Cui J, Chen J, Ji Y, Zou J, Chen H, Xiongzheng M
J Craniofac Surg 2013 May;24(3):934-6. doi: 10.1097/SCS.0b013e31828606a1. PMID: 23714914

Diagnosis

Whitehead MT, Barkovich MJ, Sidpra J, Alves CA, Mirsky DM, Öztekin Ö, Bhattacharya D, Lucato LT, Sudhakar S, Taranath A, Andronikou S, Prabhu SP, Aldinger KA, Haldipur P, Millen KJ, Barkovich AJ, Boltshauser E, Dobyns WB, Mankad K
AJNR Am J Neuroradiol 2022 Oct;43(10):1488-1493. Epub 2022 Sep 22 doi: 10.3174/ajnr.A7659. PMID: 36137655Free PMC Article
Conley LM, Phillips CD
Radiol Clin North Am 2017 Jan;55(1):53-67. doi: 10.1016/j.rcl.2016.08.007. PMID: 27890188
Blaser SI, Padfield N, Chitayat D, Forrest CR
Pediatr Radiol 2015 Sep;45 Suppl 3:S485-96. Epub 2015 Sep 7 doi: 10.1007/s00247-015-3320-1. PMID: 26346154
Dobre MC, Fischbein N
J Med Imaging Radiat Oncol 2014 Aug;58(4):458-63. Epub 2014 Jun 25 doi: 10.1111/1754-9485.12195. PMID: 24964828
Wang EW, Vandergrift WA 3rd, Schlosser RJ
Otolaryngol Clin North Am 2011 Aug;44(4):845-56, vii. doi: 10.1016/j.otc.2011.06.018. PMID: 21819875

Therapy

Baglam T, Binnetoglu A, Fatih Topuz M, Baş Ikizoglu N, Ersu R, Turan S, Sarı M
Int J Pediatr Otorhinolaryngol 2017 Apr;95:91-96. Epub 2017 Feb 11 doi: 10.1016/j.ijporl.2017.02.009. PMID: 28576543
Finsterer J, Revuelta GJ
Clin Neurol Neurosurg 2014 Dec;127:44-53. Epub 2014 Oct 2 doi: 10.1016/j.clineuro.2014.09.020. PMID: 25459242
Wang EW, Vandergrift WA 3rd, Schlosser RJ
Otolaryngol Clin North Am 2011 Aug;44(4):845-56, vii. doi: 10.1016/j.otc.2011.06.018. PMID: 21819875
Mokri B
Curr Neurol Neurosci Rep 2001 Mar;1(2):109-17. doi: 10.1007/s11910-001-0005-y. PMID: 11898506
Mokri B
Curr Pain Headache Rep 2001 Jun;5(3):284-91. doi: 10.1007/s11916-001-0045-7. PMID: 11309218

Prognosis

Li W, Xu R, Zhu B, Wang H, Zhang H, Hu L, Li H, Sun X, Yu H, Wang D
Head Neck 2022 Feb;44(2):494-504. Epub 2021 Dec 20 doi: 10.1002/hed.26962. PMID: 34931399
Society for Maternal-Fetal Medicine (SMFM), Monteagudo A
Am J Obstet Gynecol 2020 Dec;223(6):B38-B41. Epub 2020 Nov 7 doi: 10.1016/j.ajog.2020.08.184. PMID: 33168220
Blaser SI, Padfield N, Chitayat D, Forrest CR
Pediatr Radiol 2015 Sep;45 Suppl 3:S485-96. Epub 2015 Sep 7 doi: 10.1007/s00247-015-3320-1. PMID: 26346154
Bosemani T, Orman G, Boltshauser E, Tekes A, Huisman TA, Poretti A
Radiographics 2015 Jan-Feb;35(1):200-20. doi: 10.1148/rg.351140038. PMID: 25590398
Spennato P, Mirone G, Nastro A, Buonocore MC, Ruggiero C, Trischitta V, Aliberti F, Cinalli G
Childs Nerv Syst 2011 Oct;27(10):1665-81. Epub 2011 Sep 17 doi: 10.1007/s00381-011-1544-4. PMID: 21928031

Clinical prediction guides

Skadorwa T, Wierzbieniec O
Childs Nerv Syst 2022 Nov;38(11):2163-2170. Epub 2022 Aug 5 doi: 10.1007/s00381-022-05624-2. PMID: 35931858Free PMC Article
Wang C, Lockwood J, Iwanaga J, Dumont AS, Bui CJ, Tubbs RS
Neurosurg Rev 2021 Jun;44(3):1255-1258. Epub 2020 Jun 7 doi: 10.1007/s10143-020-01329-9. PMID: 32507931
Baglam T, Binnetoglu A, Fatih Topuz M, Baş Ikizoglu N, Ersu R, Turan S, Sarı M
Int J Pediatr Otorhinolaryngol 2017 Apr;95:91-96. Epub 2017 Feb 11 doi: 10.1016/j.ijporl.2017.02.009. PMID: 28576543
Blaser SI, Padfield N, Chitayat D, Forrest CR
Pediatr Radiol 2015 Sep;45 Suppl 3:S485-96. Epub 2015 Sep 7 doi: 10.1007/s00247-015-3320-1. PMID: 26346154
Westerhof W, Delleman JW, Wolters E, Dijkstra P
Arch Dermatol 1984 Dec;120(12):1579-81. PMID: 6439124

Recent systematic reviews

Stuebe CM, Rindler RS, Laack N, Carr CM, Choby G, Inwards CY, Van Gompel JJ
World Neurosurg 2023 Jun;174:157-168. Epub 2023 Mar 9 doi: 10.1016/j.wneu.2023.03.016. PMID: 36898627
Alexiou GA, Lampros M, Gavra MM, Vlachos N, Ydreos J, Boviatsis EJ
World Neurosurg 2022 Aug;164:323-329. Epub 2022 May 30 doi: 10.1016/j.wneu.2022.05.107. PMID: 35654328
Vicente A, Bravo-González LA, López-Romero A, Muñoz CS, Sánchez-Meca J
Sci Rep 2020 Nov 16;10(1):19895. doi: 10.1038/s41598-020-76984-5. PMID: 33199843Free PMC Article
Corcuera-Flores JR, Casttellanos-Cosano L, Torres-Lagares D, Serrera-Figallo MÁ, Rodríguez-Caballero Á, Machuca-Portillo G
Clin Anat 2016 Jul;29(5):555-60. Epub 2015 Dec 21 doi: 10.1002/ca.22654. PMID: 26457586
D'Antonio F, Khalil A, Garel C, Pilu G, Rizzo G, Lerman-Sagie T, Bhide A, Thilaganathan B, Manzoli L, Papageorghiou AT
Ultrasound Obstet Gynecol 2016 Jul;48(1):28-37. doi: 10.1002/uog.15755. PMID: 26394557

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