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Abnormality of the upper respiratory tract

MedGen UID:
871244
•Concept ID:
C4025727
•
Anatomical Abnormality
Synonym: Upper respiratory tract issues
 
HPO: HP:0002087

Definition

An abnormality of the upper respiratory tract. [from HPO]

Professional guidelines

PubMed

JAK inhibitors in the treatment of atopic dermatitis.
Chovatiya R, Paller AS
J Allergy Clin Immunol 2021 Oct;148(4):927-940. Epub 2021 Aug 24 doi: 10.1016/j.jaci.2021.08.009. PMID: 34437922Free PMC Article
Evaluation and Management of Children with Obstructive Sleep Apnea Syndrome.
Bitners AC, Arens R
Lung 2020 Apr;198(2):257-270. Epub 2020 Mar 12 doi: 10.1007/s00408-020-00342-5. PMID: 32166426Free PMC Article
Obstructive sleep disordered breathing in 2- to 18-year-old children: diagnosis and management.
Kaditis AG, Alonso Alvarez ML, Boudewyns A, Alexopoulos EI, Ersu R, Joosten K, Larramona H, Miano S, Narang I, Trang H, Tsaoussoglou M, Vandenbussche N, Villa MP, Van Waardenburg D, Weber S, Verhulst S
Eur Respir J 2016 Jan;47(1):69-94. Epub 2015 Nov 5 doi: 10.1183/13993003.00385-2015. PMID: 26541535

Recent clinical studies

Etiology

Pathophysiology, evaluation, and management of sleep disorders in the mucopolysaccharidoses.
Rapoport DM, Mitchell JJ
Mol Genet Metab 2017 Dec;122S:49-54. Epub 2017 Aug 25 doi: 10.1016/j.ymgme.2017.08.008. PMID: 28964643
Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: A systematic review and meta-analysis of cephalometric studies.
Neelapu BC, Kharbanda OP, Sardana HK, Balachandran R, Sardana V, Kapoor P, Gupta A, Vasamsetti S
Sleep Med Rev 2017 Feb;31:79-90. Epub 2016 Jan 30 doi: 10.1016/j.smrv.2016.01.007. PMID: 27039222
Oro-Nasal Communication.
Sahoo NK, Desai AP, Roy ID, Kulkarni V
J Craniofac Surg 2016 Sep;27(6):e529-33. doi: 10.1097/SCS.0000000000002815. PMID: 27607130
Tracheostomy Tube Placement: Early and Late Complications.
Fernandez-Bussy S, Mahajan B, Folch E, Caviedes I, Guerrero J, Majid A
J Bronchology Interv Pulmonol 2015 Oct;22(4):357-64. doi: 10.1097/LBR.0000000000000177. PMID: 26348694
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Diagnosis

Stridor in the Infant Patient.
Zalzal HG, Zalzal GH
Pediatr Clin North Am 2022 Apr;69(2):301-317. doi: 10.1016/j.pcl.2021.12.003. PMID: 35337541
Subglottic stenosis.
Jefferson ND, Cohen AP, Rutter MJ
Semin Pediatr Surg 2016 Jun;25(3):138-43. Epub 2016 Feb 20 doi: 10.1053/j.sempedsurg.2016.02.006. PMID: 27301599
Pediatric sinusitis.
Tan R, Spector S
Curr Allergy Asthma Rep 2007 Nov;7(6):421-6. doi: 10.1007/s11882-007-0064-5. PMID: 17986371
Does this patient have community-acquired pneumonia? Diagnosing pneumonia by history and physical examination.
Metlay JP, Kapoor WN, Fine MJ
JAMA 1997 Nov 5;278(17):1440-5. PMID: 9356004
Pulmonary sequestration.
O'Mara CS, Baker RR, Jeyasingham K
Surg Gynecol Obstet 1978 Oct;147(4):609-16. PMID: 360452

Therapy

Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials.
Simões EAF, Madhi SA, Muller WJ, Atanasova V, Bosheva M, Cabañas F, Baca Cots M, Domachowske JB, Garcia-Garcia ML, Grantina I, Nguyen KA, Zar HJ, Berglind A, Cummings C, Griffin MP, Takas T, Yuan Y, Wählby Hamrén U, Leach A, Villafana T
Lancet Child Adolesc Health 2023 Mar;7(3):180-189. Epub 2023 Jan 9 doi: 10.1016/S2352-4642(22)00321-2. PMID: 36634694Free PMC Article
JAK inhibitors in the treatment of atopic dermatitis.
Chovatiya R, Paller AS
J Allergy Clin Immunol 2021 Oct;148(4):927-940. Epub 2021 Aug 24 doi: 10.1016/j.jaci.2021.08.009. PMID: 34437922Free PMC Article
Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.
Chua F, Desai SR, Nicholson AG, Devaraj A, Renzoni E, Rice A, Wells AU
Ann Am Thorac Soc 2019 Nov;16(11):1351-1359. doi: 10.1513/AnnalsATS.201902-181CME. PMID: 31425665Free PMC Article
Obstructive sleep disordered breathing in 2- to 18-year-old children: diagnosis and management.
Kaditis AG, Alonso Alvarez ML, Boudewyns A, Alexopoulos EI, Ersu R, Joosten K, Larramona H, Miano S, Narang I, Trang H, Tsaoussoglou M, Vandenbussche N, Villa MP, Van Waardenburg D, Weber S, Verhulst S
Eur Respir J 2016 Jan;47(1):69-94. Epub 2015 Nov 5 doi: 10.1183/13993003.00385-2015. PMID: 26541535
Tracheostomy Tube Placement: Early and Late Complications.
Fernandez-Bussy S, Mahajan B, Folch E, Caviedes I, Guerrero J, Majid A
J Bronchology Interv Pulmonol 2015 Oct;22(4):357-64. doi: 10.1097/LBR.0000000000000177. PMID: 26348694

Prognosis

Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials.
Simões EAF, Madhi SA, Muller WJ, Atanasova V, Bosheva M, Cabañas F, Baca Cots M, Domachowske JB, Garcia-Garcia ML, Grantina I, Nguyen KA, Zar HJ, Berglind A, Cummings C, Griffin MP, Takas T, Yuan Y, Wählby Hamrén U, Leach A, Villafana T
Lancet Child Adolesc Health 2023 Mar;7(3):180-189. Epub 2023 Jan 9 doi: 10.1016/S2352-4642(22)00321-2. PMID: 36634694Free PMC Article
Pleuroparenchymal Fibroelastosis. A Review of Clinical, Radiological, and Pathological Characteristics.
Chua F, Desai SR, Nicholson AG, Devaraj A, Renzoni E, Rice A, Wells AU
Ann Am Thorac Soc 2019 Nov;16(11):1351-1359. doi: 10.1513/AnnalsATS.201902-181CME. PMID: 31425665Free PMC Article
Laryngomalacia: is there an evidence base for management?
McCaffer C, Blackmore K, Flood LM
J Laryngol Otol 2017 Nov;131(11):946-954. Epub 2017 Oct 25 doi: 10.1017/S0022215117002092. PMID: 29067893
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Does this patient have community-acquired pneumonia? Diagnosing pneumonia by history and physical examination.
Metlay JP, Kapoor WN, Fine MJ
JAMA 1997 Nov 5;278(17):1440-5. PMID: 9356004

Clinical prediction guides

Lip-Shortening Surgery.
Gatti JE
Plast Reconstr Surg 2023 Oct 1;152(4):765-772. Epub 2023 Mar 7 doi: 10.1097/PRS.0000000000010361. PMID: 36877617
Efficacy of nirsevimab against respiratory syncytial virus lower respiratory tract infections in preterm and term infants, and pharmacokinetic extrapolation to infants with congenital heart disease and chronic lung disease: a pooled analysis of randomised controlled trials.
Simões EAF, Madhi SA, Muller WJ, Atanasova V, Bosheva M, Cabañas F, Baca Cots M, Domachowske JB, Garcia-Garcia ML, Grantina I, Nguyen KA, Zar HJ, Berglind A, Cummings C, Griffin MP, Takas T, Yuan Y, Wählby Hamrén U, Leach A, Villafana T
Lancet Child Adolesc Health 2023 Mar;7(3):180-189. Epub 2023 Jan 9 doi: 10.1016/S2352-4642(22)00321-2. PMID: 36634694Free PMC Article
The role of upper airway endoscopy in craniofacial malformations.
Manica D, Schweiger C
Semin Fetal Neonatal Med 2021 Dec;26(6):101293. Epub 2021 Sep 20 doi: 10.1016/j.siny.2021.101293. PMID: 34561176
Lung disease manifestations in Down syndrome.
Danopoulos S, Deutsch GH, Dumortier C, Mariani TJ, Al Alam D
Am J Physiol Lung Cell Mol Physiol 2021 Nov 1;321(5):L892-L899. Epub 2021 Sep 1 doi: 10.1152/ajplung.00434.2020. PMID: 34469245Free PMC Article
Evaluation and Management of Children with Obstructive Sleep Apnea Syndrome.
Bitners AC, Arens R
Lung 2020 Apr;198(2):257-270. Epub 2020 Mar 12 doi: 10.1007/s00408-020-00342-5. PMID: 32166426Free PMC Article

Recent systematic reviews

Systematic literature review of the signs and symptoms of respiratory syncytial virus.
Colosia A, Costello J, McQuarrie K, Kato K, Bertzos K
Influenza Other Respir Viruses 2023 Feb;17(2):e13100. Epub 2023 Feb 5 doi: 10.1111/irv.13100. PMID: 36824394Free PMC Article
Will This Patient Be Difficult to Intubate?: The Rational Clinical Examination Systematic Review.
Detsky ME, Jivraj N, Adhikari NK, Friedrich JO, Pinto R, Simel DL, Wijeysundera DN, Scales DC
JAMA 2019 Feb 5;321(5):493-503. doi: 10.1001/jama.2018.21413. PMID: 30721300
Fecal transplantation for treatment of inflammatory bowel disease.
Imdad A, Nicholson MR, Tanner-Smith EE, Zackular JP, Gomez-Duarte OG, Beaulieu DB, Acra S
Cochrane Database Syst Rev 2018 Nov 13;11(11):CD012774. doi: 10.1002/14651858.CD012774.pub2. PMID: 30480772Free PMC Article
Laryngomalacia: is there an evidence base for management?
McCaffer C, Blackmore K, Flood LM
J Laryngol Otol 2017 Nov;131(11):946-954. Epub 2017 Oct 25 doi: 10.1017/S0022215117002092. PMID: 29067893
Craniofacial and upper airway morphology in adult obstructive sleep apnea patients: A systematic review and meta-analysis of cephalometric studies.
Neelapu BC, Kharbanda OP, Sardana HK, Balachandran R, Sardana V, Kapoor P, Gupta A, Vasamsetti S
Sleep Med Rev 2017 Feb;31:79-90. Epub 2016 Jan 30 doi: 10.1016/j.smrv.2016.01.007. PMID: 27039222

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