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Abnormality of the spleen

MedGen UID:
871264
Concept ID:
C4025749
Anatomical Abnormality
HPO: HP:0001743

Definition

An abnormality of the spleen. [from HPO]

Conditions with this feature

Tuftsin deficiency
MedGen UID:
98311
Concept ID:
C0398741
Disease or Syndrome
Cephalin lipidosis
MedGen UID:
395225
Concept ID:
C1859307
Disease or Syndrome

Professional guidelines

PubMed

Ofovwe GE, Ibadin OM, Ofovwe EC, Okolo AA
J Neurol Sci 2002 Aug 15;200(1-2):49-52. doi: 10.1016/s0022-510x(02)00128-4. PMID: 12127675
Gavant ML, Schurr M, Flick PA, Croce MA, Fabian TC, Gold RE
AJR Am J Roentgenol 1997 Jan;168(1):207-12. doi: 10.2214/ajr.168.1.8976947. PMID: 8976947

Recent clinical studies

Etiology

Williams RF, Grewal H, Jamshidi R, Naik-Mathuria B, Price M, Russell RT, Vogel A, Notrica DM, Stylianos S, Petty J
J Pediatr Surg 2023 Aug;58(8):1411-1418. Epub 2023 Mar 23 doi: 10.1016/j.jpedsurg.2023.03.012. PMID: 37117078
Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Lee GM
Hematology Am Soc Hematol Educ Program 2020 Dec 4;2020(1):328-335. doi: 10.1182/hematology.2020000117. PMID: 33275684Free PMC Article
Harrison C, Kiladjian JJ, Al-Ali HK, Gisslinger H, Waltzman R, Stalbovskaya V, McQuitty M, Hunter DS, Levy R, Knoops L, Cervantes F, Vannucchi AM, Barbui T, Barosi G
N Engl J Med 2012 Mar 1;366(9):787-98. doi: 10.1056/NEJMoa1110556. PMID: 22375970
Buehner M, Baker MS
Surg Gynecol Obstet 1992 Oct;175(4):373-87. PMID: 1411897

Diagnosis

Lin Z, Cao Q
Rev Esp Enferm Dig 2023 Nov;115(11):665-666. doi: 10.17235/reed.2023.9964/2023. PMID: 37882202
Vancauwenberghe T, Snoeckx A, Vanbeckevoort D, Dymarkowski S, Vanhoenacker FM
Singapore Med J 2015 Mar;56(3):133-44. doi: 10.11622/smedj.2015040. PMID: 25820845Free PMC Article
Davenport M
Semin Pediatr Surg 2012 Aug;21(3):175-84. doi: 10.1053/j.sempedsurg.2012.05.010. PMID: 22800970
Balaji KC, Caldamone AA, Rabinowitz R, Ortenberg J, Diamond DA
J Urol 1996 Aug;156(2 Pt 2):854-6. doi: 10.1097/00005392-199608001-00086. PMID: 8683800
Buehner M, Baker MS
Surg Gynecol Obstet 1992 Oct;175(4):373-87. PMID: 1411897

Therapy

Verstovsek S, Gerds AT, Vannucchi AM, Al-Ali HK, Lavie D, Kuykendall AT, Grosicki S, Iurlo A, Goh YT, Lazaroiu MC, Egyed M, Fox ML, McLornan D, Perkins A, Yoon SS, Gupta V, Kiladjian JJ, Granacher N, Lee SE, Ocroteala L, Passamonti F, Harrison CN, Klencke BJ, Ro S, Donahue R, Kawashima J, Mesa R; MOMENTUM Study Investigators
Lancet 2023 Jan 28;401(10373):269-280. doi: 10.1016/S0140-6736(22)02036-0. PMID: 36709073
Tefferi A
Am J Hematol 2023 May;98(5):801-821. Epub 2023 Feb 6 doi: 10.1002/ajh.26857. PMID: 36680511
Mesa RA, Kiladjian JJ, Catalano JV, Devos T, Egyed M, Hellmann A, McLornan D, Shimoda K, Winton EF, Deng W, Dubowy RL, Maltzman JD, Cervantes F, Gotlib J
J Clin Oncol 2017 Dec 1;35(34):3844-3850. Epub 2017 Sep 20 doi: 10.1200/JCO.2017.73.4418. PMID: 28930494Free PMC Article
Zaorsky NG, Williams GR, Barta SK, Esnaola NF, Kropf PL, Hayes SB, Meyer JE
Cancer Treat Rev 2017 Feb;53:47-52. Epub 2016 Dec 22 doi: 10.1016/j.ctrv.2016.11.016. PMID: 28063304Free PMC Article
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172

Prognosis

Bonfiglio F, Bruscaggin A, Guidetti F, Terzi di Bergamo L, Faderl M, Spina V, Condoluci A, Bonomini L, Forestieri G, Koch R, Piffaretti D, Pini K, Pirosa MC, Cittone MG, Arribas A, Lucioni M, Ghilardi G, Wu W, Arcaini L, Baptista MJ, Bastidas G, Bea S, Boldorini R, Broccoli A, Buehler MM, Canzonieri V, Cascione L, Ceriani L, Cogliatti S, Corradini P, Derenzini E, Devizzi L, Dietrich S, Elia AR, Facchetti F, Gaidano G, Garcia JF, Gerber B, Ghia P, Gomes da Silva M, Gritti G, Guidetti A, Hitz F, Inghirami G, Ladetto M, Lopez-Guillermo A, Lucchini E, Maiorana A, Marasca R, Matutes E, Meignin V, Merli M, Moccia A, Mollejo M, Montalban C, Novak U, Oscier DG, Passamonti F, Piazza F, Pizzolitto S, Rambaldi A, Sabattini E, Salles G, Santambrogio E, Scarfò L, Stathis A, Stüssi G, Geyer JT, Tapia G, Tarella C, Thieblemont C, Tousseyn T, Tucci A, Vanini G, Visco C, Vitolo U, Walewska R, Zaja F, Zenz T, Zinzani PL, Khiabanian H, Calcinotto A, Bertoni F, Bhagat G, Campo E, De Leval L, Dirnhofer S, Pileri SA, Piris MA, Traverse-Glehen A, Tzankov A, Paulli M, Ponzoni M, Mazzucchelli L, Cavalli F, Zucca E, Rossi D
Blood 2022 Feb 3;139(5):732-747. doi: 10.1182/blood.2021012386. PMID: 34653238
Zaorsky NG, Williams GR, Barta SK, Esnaola NF, Kropf PL, Hayes SB, Meyer JE
Cancer Treat Rev 2017 Feb;53:47-52. Epub 2016 Dec 22 doi: 10.1016/j.ctrv.2016.11.016. PMID: 28063304Free PMC Article
Ioannidis I, Kahn AG
Arch Pathol Lab Med 2015 Feb;139(2):278-82. doi: 10.5858/arpa.2013-0656-RS. PMID: 25611113
Harrison C, Kiladjian JJ, Al-Ali HK, Gisslinger H, Waltzman R, Stalbovskaya V, McQuitty M, Hunter DS, Levy R, Knoops L, Cervantes F, Vannucchi AM, Barbui T, Barosi G
N Engl J Med 2012 Mar 1;366(9):787-98. doi: 10.1056/NEJMoa1110556. PMID: 22375970
Di Sabatino A, Carsetti R, Corazza GR
Lancet 2011 Jul 2;378(9785):86-97. Epub 2011 Apr 5 doi: 10.1016/S0140-6736(10)61493-6. PMID: 21474172

Clinical prediction guides

Hui D, Liu L, Azami NLB, Song J, Huang Y, Xu W, Wu C, Xie D, Jiang Y, Bian Y, Sun M
Front Endocrinol (Lausanne) 2022;13:1107071. Epub 2023 Jan 19 doi: 10.3389/fendo.2022.1107071. PMID: 36743913Free PMC Article
Tamber GS, Chévarie-Davis M, Warner M, Séguin C, Caron C, Michel RP
Histopathology 2021 Dec;79(6):1072-1086. Epub 2021 Sep 22 doi: 10.1111/his.14535. PMID: 34333806
Luu S, Woolley IJ, Andrews RK
Platelets 2021 Jan 2;32(1):47-52. Epub 2020 Feb 27 doi: 10.1080/09537104.2020.1732322. PMID: 32106750
Jones SA, McGovern M, Lidove O, Giugliani R, Mistry PK, Dionisi-Vici C, Munoz-Rojas MV, Nalysnyk L, Schecter AD, Wasserstein M
Mol Genet Metab 2020 Sep-Oct;131(1-2):116-123. Epub 2020 Jun 24 doi: 10.1016/j.ymgme.2020.06.008. PMID: 32616389
Frescura C, Ho SY, Giordano M, Thiene G
Cardiovasc Pathol 2020 Jul-Aug;47:107205. Epub 2020 Jan 16 doi: 10.1016/j.carpath.2020.107205. PMID: 32179252

Recent systematic reviews

Tan ET, Wilkinson D, Edafe O
Clin Otolaryngol 2022 Nov;47(6):611-619. Epub 2022 Jul 29 doi: 10.1111/coa.13965. PMID: 35834363
Bough GM, Gargan KE, Cleeve SJ, Farrell S
Surgeon 2022 Oct;20(5):e296-e305. Epub 2021 Oct 16 doi: 10.1016/j.surge.2021.08.006. PMID: 34666939
Ganarin A, Fascetti Leon F, La Pergola E, Gamba P
J Laparoendosc Adv Surg Tech A 2021 Apr;31(4):468-477. Epub 2021 Jan 11 doi: 10.1089/lap.2020.0759. PMID: 33428514
Vikse J, Sanna B, Henry BM, Taterra D, Sanna S, Pękala PA, Walocha JA, Tomaszewski KA
Int J Surg 2017 Sep;45:18-28. Epub 2017 Jul 15 doi: 10.1016/j.ijsu.2017.07.045. PMID: 28716661
Zaorsky NG, Williams GR, Barta SK, Esnaola NF, Kropf PL, Hayes SB, Meyer JE
Cancer Treat Rev 2017 Feb;53:47-52. Epub 2016 Dec 22 doi: 10.1016/j.ctrv.2016.11.016. PMID: 28063304Free PMC Article

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