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Abnormal tricuspid valve morphology

MedGen UID:
871267
•Concept ID:
C4025753
•
Anatomical Abnormality
Synonym: Abnormality of the tricuspid valve
 
HPO: HP:0001702

Definition

Any structural anomaly of the tricuspid valve. [from HPO]

Conditions with this feature

Heterotaxy, visceral, 7, autosomal
MedGen UID:
902629
•Concept ID:
C4225217
•
Disease or Syndrome
Autosomal visceral heterotaxy-7 is an autosomal recessive developmental disorder characterized by complex congenital heart malformations and/or situs inversus and caused by defects in the normal left-right asymmetric positioning of internal organs. The phenotype is variable (summary by Guimier et al., 2015). For a discussion of the genetic heterogeneity of visceral heterotaxy, see HTX1 (306955).
See: Condition Record
Heterotaxy, visceral, 7, autosomal

Professional guidelines

PubMed

Echocardiographic criteria to detect unicuspid aortic valve morphology.
Ewen S, Karliova I, Weber P, Schirmer SH, Abdul-Khaliq H, Schöpe J, Mahfoud F, Schäfers HJ
Eur Heart J Cardiovasc Imaging 2019 Jan 1;20(1):40-44. doi: 10.1093/ehjci/jex344. PMID: 29346529
Prenatal diagnosis of functionally univentricular heart, associations and perinatal outcomes.
Wolter A, Nosbüsch S, Kawecki A, Degenhardt J, Enzensberger C, Graupner O, Vorisek C, Akintürk H, Yerebakan C, Khalil M, Schranz D, Ritgen J, Stressig R, Axt-Fliedner R
Prenat Diagn 2016 Jun;36(6):545-54. Epub 2016 May 10 doi: 10.1002/pd.4821. PMID: 27061183
Diagnosis and management of congenital heart disease in the adult.
Moodie DS
Cardiol Rev 2001 Sep-Oct;9(5):276-81. doi: 10.1097/00045415-200109000-00007. PMID: 11520451

Recent clinical studies

Etiology

Transcatheter aortic valve implantation in low-risk tricuspid or bicuspid aortic stenosis: the NOTION-2 trial.
Jørgensen TH, Thyregod HGH, Savontaus M, Willemen Y, Bleie Ø, Tang M, Niemela M, Angerås O, Gudmundsdóttir IJ, Sartipy U, Dagnegaard H, Laine M, Rück A, Piuhola J, Petursson P, Christiansen EH, Malmberg M, Olsen PS, Haaverstad R, Sondergaard L, De Backer O; NOTION-2 investigators
Eur Heart J 2024 Oct 5;45(37):3804-3814. doi: 10.1093/eurheartj/ehae331. PMID: 38747246
Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Anatomy and Physiology of the Tricuspid Valve.
Dahou A, Levin D, Reisman M, Hahn RT
JACC Cardiovasc Imaging 2019 Mar;12(3):458-468. doi: 10.1016/j.jcmg.2018.07.032. PMID: 30846121
Evaluation of tricuspid valve morphology and function by transthoracic three-dimensional echocardiography.
Muraru D, Badano LP, Sarais C, Soldà E, Iliceto S
Curr Cardiol Rep 2011 Jun;13(3):242-9. doi: 10.1007/s11886-011-0176-3. PMID: 21365261

Diagnosis

Ebstein's Anomaly: From Fetus to Adult-Literature Review and Pathway for Patient Care.
Ramcharan TKW, Goff DA, Greenleaf CE, Shebani SO, Salazar JD, Corno AF
Pediatr Cardiol 2022 Oct;43(7):1409-1428. Epub 2022 Apr 23 doi: 10.1007/s00246-022-02908-x. PMID: 35460366
Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490
Cardiac imaging in Ebstein anomaly.
Qureshi MY, O'Leary PW, Connolly HM
Trends Cardiovasc Med 2018 Aug;28(6):403-409. Epub 2018 Jan 12 doi: 10.1016/j.tcm.2018.01.002. PMID: 29409687
Understanding Ebstein's malformation.
Anderson RH
Cardiol Young 2015 Jan;25(1):137-8. Epub 2014 Aug 28 doi: 10.1017/S1047951114001565. PMID: 25165895
Tricuspid valve disease.
Shah PM, Raney AA
Curr Probl Cardiol 2008 Feb;33(2):47-84. doi: 10.1016/j.cpcardiol.2007.10.004. PMID: 18222317

Therapy

Transcatheter aortic valve implantation in low-risk tricuspid or bicuspid aortic stenosis: the NOTION-2 trial.
Jørgensen TH, Thyregod HGH, Savontaus M, Willemen Y, Bleie Ø, Tang M, Niemela M, Angerås O, Gudmundsdóttir IJ, Sartipy U, Dagnegaard H, Laine M, Rück A, Piuhola J, Petursson P, Christiansen EH, Malmberg M, Olsen PS, Haaverstad R, Sondergaard L, De Backer O; NOTION-2 investigators
Eur Heart J 2024 Oct 5;45(37):3804-3814. doi: 10.1093/eurheartj/ehae331. PMID: 38747246
Ebstein's Anomaly.
Holst KA, Connolly HM, Dearani JA
Methodist Debakey Cardiovasc J 2019 Apr-Jun;15(2):138-144. doi: 10.14797/mdcj-15-2-138. PMID: 31384377Free PMC Article
Neonatal Ebstein Anomaly.
Kumar TKS, Boston US, Knott-Craig CJ
Semin Thorac Cardiovasc Surg 2017 Autumn;29(3):331-337. Epub 2017 Sep 25 doi: 10.1053/j.semtcvs.2017.09.006. PMID: 28958645
Reexamining remodeling.
Schäfers HJ, Raddatz A, Schmied W, Takahashi H, Miura Y, Kunihara T, Aicher D
J Thorac Cardiovasc Surg 2015 Feb;149(2 Suppl):S30-6. Epub 2014 Sep 18 doi: 10.1016/j.jtcvs.2014.09.048. PMID: 25439784
Pathology of calcific aortic stenosis.
Ladich E, Nakano M, Carter-Monroe N, Virmani R
Future Cardiol 2011 Sep;7(5):629-42. doi: 10.2217/fca.11.53. PMID: 21929343

Prognosis

Ebstein Anomaly in the Adult Patient.
Fuchs MM, Connolly HM
Cardiol Clin 2020 Aug;38(3):353-363. Epub 2020 Jun 6 doi: 10.1016/j.ccl.2020.04.004. PMID: 32622490
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Tricuspid Valve Imaging and Intervention in Pediatric and Adult Patients With Congenital Heart Disease.
Qureshi MY, Sommer RJ, Cabalka AK
JACC Cardiovasc Imaging 2019 Apr;12(4):637-651. doi: 10.1016/j.jcmg.2018.10.036. PMID: 30947906
Cardiac imaging in Ebstein anomaly.
Qureshi MY, O'Leary PW, Connolly HM
Trends Cardiovasc Med 2018 Aug;28(6):403-409. Epub 2018 Jan 12 doi: 10.1016/j.tcm.2018.01.002. PMID: 29409687
Congenitally corrected transposition.
Wallis GA, Debich-Spicer D, Anderson RH
Orphanet J Rare Dis 2011 May 14;6:22. doi: 10.1186/1750-1172-6-22. PMID: 21569592Free PMC Article

Clinical prediction guides

Transcatheter aortic valve implantation in low-risk tricuspid or bicuspid aortic stenosis: the NOTION-2 trial.
Jørgensen TH, Thyregod HGH, Savontaus M, Willemen Y, Bleie Ø, Tang M, Niemela M, Angerås O, Gudmundsdóttir IJ, Sartipy U, Dagnegaard H, Laine M, Rück A, Piuhola J, Petursson P, Christiansen EH, Malmberg M, Olsen PS, Haaverstad R, Sondergaard L, De Backer O; NOTION-2 investigators
Eur Heart J 2024 Oct 5;45(37):3804-3814. doi: 10.1093/eurheartj/ehae331. PMID: 38747246
Diagnosis of major heart defects by routine first-trimester ultrasound examination: association with increased nuchal translucency, tricuspid regurgitation and abnormal flow in ductus venosus.
Minnella GP, Crupano FM, Syngelaki A, Zidere V, Akolekar R, Nicolaides KH
Ultrasound Obstet Gynecol 2020 May;55(5):637-644. doi: 10.1002/uog.21956. PMID: 31875326
Ebstein's Anomaly.
Holst KA, Connolly HM, Dearani JA
Methodist Debakey Cardiovasc J 2019 Apr-Jun;15(2):138-144. doi: 10.14797/mdcj-15-2-138. PMID: 31384377Free PMC Article
Cardiac imaging in Ebstein anomaly.
Qureshi MY, O'Leary PW, Connolly HM
Trends Cardiovasc Med 2018 Aug;28(6):403-409. Epub 2018 Jan 12 doi: 10.1016/j.tcm.2018.01.002. PMID: 29409687
Reexamining remodeling.
Schäfers HJ, Raddatz A, Schmied W, Takahashi H, Miura Y, Kunihara T, Aicher D
J Thorac Cardiovasc Surg 2015 Feb;149(2 Suppl):S30-6. Epub 2014 Sep 18 doi: 10.1016/j.jtcvs.2014.09.048. PMID: 25439784

Recent systematic reviews

Diagnostic accuracy of prenatal ultrasound in coarctation of aorta: systematic review and individual participant data meta-analysis.
Villalaín C, D'Antonio F, Flacco ME, Gómez-Montes E, Herraiz I, Deiros-Bronte L, Maskatia SA, Phillips AA, Contro E, Fricke K, Bhawna A, Beattie MJ, Moon-Grady AJ, Durand I, Slodki M, Respondek-Liberska M, Patel C, Kawamura H, Rizzo G, Pagani G, Galindo A
Ultrasound Obstet Gynecol 2024 Apr;63(4):446-456. Epub 2024 Mar 9 doi: 10.1002/uog.27576. PMID: 38197327
Clinical outcomes and the impact of valve morphology for transcatheter aortic valve replacement in bicuspid aortic valves: A systematic review and meta-analysis.
Gupta R, Mahmoudi E, Behnoush AH, Malik AH, Mahajan P, Lin M, Bandyopadhyay D, Goel A, Chakraborty S, Aedma SK, Gupta HB, Vyas AV, Combs WG, Mathur M, Yakubov SJ, Patel NC
Catheter Cardiovasc Interv 2023 Oct;102(4):721-730. Epub 2023 Aug 21 doi: 10.1002/ccd.30808. PMID: 37605512
Impact of Valve Morphology on the Prevalence of Coronary Artery Disease: A Systematic Review and Meta-Analysis.
Poggio P, Cavallotti L, Songia P, Di Minno A, Ambrosino P, Mammana L, Parolari A, Alamanni F, Tremoli E, Di Minno MN
J Am Heart Assoc 2016 May 18;5(5) doi: 10.1161/JAHA.116.003200. PMID: 27194004Free PMC Article
Surgical thresholds for bicuspid aortic valve associated aortopathy.
Hardikar AA, Marwick TH
JACC Cardiovasc Imaging 2013 Dec;6(12):1311-20. doi: 10.1016/j.jcmg.2013.10.005. PMID: 24332283
Complex Ebstein's malformation: defining preoperative cardiac anatomy and function.
Negoi RI, Ispas AT, Ghiorghiu I, Filipoiu F, Negoi I, Hostiuc M, Hostiuc S, Ginghina C
J Card Surg 2013 Jan;28(1):70-81. doi: 10.1111/jocs.12032. PMID: 23330581

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