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Abnormality of the frontal hairline

MedGen UID:
871346
Concept ID:
C4025839
Anatomical Abnormality
Synonym: Abnormality of hairline at front of head
 
HPO: HP:0000599

Definition

An anomaly in the placement or shape of the hairline (trichion) on the forehead, that is, the border between skin on the forehead that has head hair and that does not. [from HPO]

Professional guidelines

PubMed

Starace M, Orlando G, Alessandrini A, Piraccini BM
Am J Clin Dermatol 2020 Feb;21(1):69-84. doi: 10.1007/s40257-019-00479-x. PMID: 31677111
Carmina E, Azziz R, Bergfeld W, Escobar-Morreale HF, Futterweit W, Huddleston H, Lobo R, Olsen E
J Clin Endocrinol Metab 2019 Jul 1;104(7):2875-2891. doi: 10.1210/jc.2018-02548. PMID: 30785992
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855

Recent clinical studies

Etiology

Özcan D
An Bras Dermatol 2022 Mar-Apr;97(2):166-172. Epub 2022 Jan 13 doi: 10.1016/j.abd.2021.06.006. PMID: 35033390Free PMC Article
Kruszka P, Addissie YA, Tekendo-Ngongang C, Jones KL, Savage SK, Gupta N, Sirisena ND, Dissanayake VHW, Paththinige CS, Aravena T, Nampoothiri S, Yesodharan D, Girisha KM, Patil SJ, Jamuar SS, Goh JC, Utari A, Sihombing N, Mishra R, Chitrakar NS, Iriele BC, Lulseged E, Megarbane A, Uwineza A, Oyenusi EE, Olopade OB, Fasanmade OA, Duenas-Roque MM, Thong MK, Tung JYL, Mok GTK, Fleischer N, Rwegerera GM, de Herreros MB, Watts J, Fieggen K, Huckstadt V, Moresco A, Obregon MG, Hussen DF, Ashaat NA, Ashaat EA, Chung BHY, Badoe E, Faradz SMH, El Ruby MO, Shotelersuk V, Wonkam A, Ekure EN, Phadke SR, Richieri-Costa A, Muenke M
Am J Med Genet A 2020 Feb;182(2):303-313. Epub 2019 Dec 19 doi: 10.1002/ajmg.a.61461. PMID: 31854143Free PMC Article
Secchin P, Quintella DC, Paula NÁO, Andrade LCDS, Sodré CT
An Bras Dermatol 2019;94(4):416-421. Epub 2019 Oct 17 doi: 10.1590/abd1806-4841.20197797. PMID: 31644613Free PMC Article
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855
Woods RH, Ul-Haq E, Wilkie AOM, Jayamohan J, Richards PG, Johnson D, Lester T, Wall SA
Plast Reconstr Surg 2009 Jun;123(6):1801-1810. doi: 10.1097/PRS.0b013e3181a3f391. PMID: 19483581Free PMC Article

Diagnosis

Kruszka P, Addissie YA, Tekendo-Ngongang C, Jones KL, Savage SK, Gupta N, Sirisena ND, Dissanayake VHW, Paththinige CS, Aravena T, Nampoothiri S, Yesodharan D, Girisha KM, Patil SJ, Jamuar SS, Goh JC, Utari A, Sihombing N, Mishra R, Chitrakar NS, Iriele BC, Lulseged E, Megarbane A, Uwineza A, Oyenusi EE, Olopade OB, Fasanmade OA, Duenas-Roque MM, Thong MK, Tung JYL, Mok GTK, Fleischer N, Rwegerera GM, de Herreros MB, Watts J, Fieggen K, Huckstadt V, Moresco A, Obregon MG, Hussen DF, Ashaat NA, Ashaat EA, Chung BHY, Badoe E, Faradz SMH, El Ruby MO, Shotelersuk V, Wonkam A, Ekure EN, Phadke SR, Richieri-Costa A, Muenke M
Am J Med Genet A 2020 Feb;182(2):303-313. Epub 2019 Dec 19 doi: 10.1002/ajmg.a.61461. PMID: 31854143Free PMC Article
Starace M, Orlando G, Alessandrini A, Piraccini BM
Am J Clin Dermatol 2020 Feb;21(1):69-84. doi: 10.1007/s40257-019-00479-x. PMID: 31677111
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Camacho-Martínez FM
Semin Cutan Med Surg 2009 Mar;28(1):19-32. doi: 10.1016/j.sder.2009.01.001. PMID: 19341939

Therapy

Starace M, Orlando G, Alessandrini A, Piraccini BM
Am J Clin Dermatol 2020 Feb;21(1):69-84. doi: 10.1007/s40257-019-00479-x. PMID: 31677111
Carmina E, Azziz R, Bergfeld W, Escobar-Morreale HF, Futterweit W, Huddleston H, Lobo R, Olsen E
J Clin Endocrinol Metab 2019 Jul 1;104(7):2875-2891. doi: 10.1210/jc.2018-02548. PMID: 30785992
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Camacho-Martínez FM
Semin Cutan Med Surg 2009 Mar;28(1):19-32. doi: 10.1016/j.sder.2009.01.001. PMID: 19341939

Prognosis

Lis-Święty A, Miziołek B, Ranosz-Janicka I, Bierzyńska-Macyszyn G, Brzezińska-Wcisło L
J Cosmet Dermatol 2018 Apr;17(2):268-273. Epub 2017 Jul 20 doi: 10.1111/jocd.12379. PMID: 28727235
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855
Piraccini BM, Alessandrini A
G Ital Dermatol Venereol 2014 Feb;149(1):15-24. PMID: 24566563
Adès LC
Clin Dysmorphol 2008 Oct;17(4):243-8. doi: 10.1097/MCD.0b013e328303e5d3. PMID: 18978651

Clinical prediction guides

Kalantar-Hormozi A, Noori M, Karimi A
J Craniofac Surg 2023 Nov-Dec 01;34(8):e790-e793. Epub 2023 Aug 25 doi: 10.1097/SCS.0000000000009679. PMID: 37622550
Wiel LC, Bruno I, Barbi E, Sirchia F
Ital J Pediatr 2022 May 12;48(1):72. doi: 10.1186/s13052-022-01267-w. PMID: 35550183Free PMC Article
Secchin P, Quintella DC, Paula NÁO, Andrade LCDS, Sodré CT
An Bras Dermatol 2019;94(4):416-421. Epub 2019 Oct 17 doi: 10.1590/abd1806-4841.20197797. PMID: 31644613Free PMC Article
Kanti V, Constantinou A, Reygagne P, Vogt A, Kottner J, Blume-Peytavi U
J Eur Acad Dermatol Venereol 2019 Oct;33(10):1976-1983. Epub 2019 Jul 1 doi: 10.1111/jdv.15735. PMID: 31179579
Goodman NF, Cobin RH, Futterweit W, Glueck JS, Legro RS, Carmina E; American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES)
Endocr Pract 2015 Nov;21(11):1291-300. doi: 10.4158/EP15748.DSC. PMID: 26509855

Recent systematic reviews

Carmina E, Azziz R, Bergfeld W, Escobar-Morreale HF, Futterweit W, Huddleston H, Lobo R, Olsen E
J Clin Endocrinol Metab 2019 Jul 1;104(7):2875-2891. doi: 10.1210/jc.2018-02548. PMID: 30785992

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