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Abnormality of the orbital region

MedGen UID:
871367
•Concept ID:
C4025863
•
Anatomical Abnormality
Synonyms: Abnormality of the eye region; Abnormality of the region around the eyes; Anomaly of the orbital region of the face; Deformity of the orbital region of the face; Malformation of the orbital region of the face
 
HPO: HP:0000315

Conditions with this feature

Dwarfism, intellectual disability, and eye abnormality
MedGen UID:
208664
•Concept ID:
C0796076
•
Disease or Syndrome
Delayed growth and mental development with ocular disorders.
See: Condition Record
Dwarfism, intellectual disability, and eye abnormality

Professional guidelines

PubMed

Children and young adults with anophthalmia and microphthalmia: Diagnosis and Management.
Taha Najim R, Topa A, Jugård Y, Casslén B, Odersjö M, Andersson Grönlund M
Acta Ophthalmol 2020 Dec;98(8):848-858. Epub 2020 May 21 doi: 10.1111/aos.14427. PMID: 32436650
The Management of Trigonoscaphocephaly as a Result of Combined Metopic and Sagittal Synostosis.
Dobbs TD, Salahuddin O, Jayamohan J, Richards P, Magdum S, Wall SA, Johnson D
Plast Reconstr Surg 2017 Jun;139(6):1325e-1332e. doi: 10.1097/PRS.0000000000003371. PMID: 28538575
Management of Orbital and Periocular Vascular Anomalies.
Stacey AW, Gemmete JJ, Kahana A
Ophthalmic Plast Reconstr Surg 2015 Nov-Dec;31(6):427-36. doi: 10.1097/IOP.0000000000000504. PMID: 26560200

Recent clinical studies

Etiology

Pterional Approach.
Luzzi S, Giotta Lucifero A, Bruno N, Baldoncini M, Campero A, Galzio R
Acta Biomed 2022 Mar 21;92(S4):e2021346. doi: 10.23750/abm.v92iS4.12775. PMID: 35441604Free PMC Article
(18)F-FDG brain PET hypometabolism in patients with long COVID.
Guedj E, Campion JY, Dudouet P, Kaphan E, Bregeon F, Tissot-Dupont H, Guis S, Barthelemy F, Habert P, Ceccaldi M, Million M, Raoult D, Cammilleri S, Eldin C
Eur J Nucl Med Mol Imaging 2021 Aug;48(9):2823-2833. Epub 2021 Jan 26 doi: 10.1007/s00259-021-05215-4. PMID: 33501506Free PMC Article
Common and distinct abnormal frontal-limbic system structural and functional patterns in patients with major depression and bipolar disorder.
Chen L, Wang Y, Niu C, Zhong S, Hu H, Chen P, Zhang S, Chen G, Deng F, Lai S, Wang J, Huang L, Huang R
Neuroimage Clin 2018;20:42-50. Epub 2018 Jul 6 doi: 10.1016/j.nicl.2018.07.002. PMID: 30069426Free PMC Article
Structural and functional brain abnormalities in schizophrenia: A cross-sectional study at different stages of the disease.
Zhao C, Zhu J, Liu X, Pu C, Lai Y, Chen L, Yu X, Hong N
Prog Neuropsychopharmacol Biol Psychiatry 2018 Apr 20;83:27-32. Epub 2017 Dec 29 doi: 10.1016/j.pnpbp.2017.12.017. PMID: 29292241
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938

Diagnosis

(18)F-FDG brain PET hypometabolism in patients with long COVID.
Guedj E, Campion JY, Dudouet P, Kaphan E, Bregeon F, Tissot-Dupont H, Guis S, Barthelemy F, Habert P, Ceccaldi M, Million M, Raoult D, Cammilleri S, Eldin C
Eur J Nucl Med Mol Imaging 2021 Aug;48(9):2823-2833. Epub 2021 Jan 26 doi: 10.1007/s00259-021-05215-4. PMID: 33501506Free PMC Article
Brain MRI in Parkinson's disease.
Meijer FJ, Goraj B
Front Biosci (Elite Ed) 2014 Jun 1;6(2):360-9. doi: 10.2741/E711. PMID: 24896211
Abnormalities of the globe.
Roy AA, Davagnanam I, Evanson J
Clin Radiol 2012 Oct;67(10):1011-22. Epub 2012 May 29 doi: 10.1016/j.crad.2012.03.006. PMID: 22647655
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Exfoliation syndrome.
Ritch R, Schlötzer-Schrehardt U
Surv Ophthalmol 2001 Jan-Feb;45(4):265-315. doi: 10.1016/s0039-6257(00)00196-x. PMID: 11166342

Therapy

Orbital cavernous haemangioma; profile and outcome of 76 patients managed surgically.
Clarós P, Choffor-Nchinda E, Lopez-Fortuny M, Claros A, Quintana S
Acta Otolaryngol 2019 Aug;139(8):720-725. Epub 2019 Jun 1 doi: 10.1080/00016489.2019.1618913. PMID: 31155992
Percutaneous sclerotherapy of para-orbital and orbital venous malformation: A single center, case series.
Ahmad S, Akhtar FK
Phlebology 2019 Jun;34(5):355-361. Epub 2018 Oct 18 doi: 10.1177/0268355518805364. PMID: 30336759
Management of Orbital and Periocular Vascular Anomalies.
Stacey AW, Gemmete JJ, Kahana A
Ophthalmic Plast Reconstr Surg 2015 Nov-Dec;31(6):427-36. doi: 10.1097/IOP.0000000000000504. PMID: 26560200
Dangerous extracranial-intracranial anastomoses and supply to the cranial nerves: vessels the neurointerventionalist needs to know.
Geibprasert S, Pongpech S, Armstrong D, Krings T
AJNR Am J Neuroradiol 2009 Sep;30(8):1459-68. Epub 2009 Mar 11 doi: 10.3174/ajnr.A1500. PMID: 19279274Free PMC Article
Intergroup rhabdomyosarcoma study-IV: results for patients with nonmetastatic disease.
Crist WM, Anderson JR, Meza JL, Fryer C, Raney RB, Ruymann FB, Breneman J, Qualman SJ, Wiener E, Wharam M, Lobe T, Webber B, Maurer HM, Donaldson SS
J Clin Oncol 2001 Jun 15;19(12):3091-102. doi: 10.1200/JCO.2001.19.12.3091. PMID: 11408506

Prognosis

Structural and functional brain abnormalities in schizophrenia: A cross-sectional study at different stages of the disease.
Zhao C, Zhu J, Liu X, Pu C, Lai Y, Chen L, Yu X, Hong N
Prog Neuropsychopharmacol Biol Psychiatry 2018 Apr 20;83:27-32. Epub 2017 Dec 29 doi: 10.1016/j.pnpbp.2017.12.017. PMID: 29292241
Maxillary sinus aplasia.
Chrcanovic BR, Freire-Maia B
Oral Maxillofac Surg 2010 Sep;14(3):187-91. doi: 10.1007/s10006-009-0200-6. PMID: 20091417
The Arrhinias.
Tessier P, Ciminello FS, Wolfe SA
Scand J Plast Reconstr Surg Hand Surg 2009;43(4):177-96. doi: 10.1080/02844310802517259. PMID: 19401938
Orbital vascular anatomy.
Hayreh SS
Eye (Lond) 2006 Oct;20(10):1130-44. doi: 10.1038/sj.eye.6702377. PMID: 17019411
Exfoliation syndrome.
Ritch R, Schlötzer-Schrehardt U
Surv Ophthalmol 2001 Jan-Feb;45(4):265-315. doi: 10.1016/s0039-6257(00)00196-x. PMID: 11166342

Clinical prediction guides

Orbital cavernous haemangioma; profile and outcome of 76 patients managed surgically.
Clarós P, Choffor-Nchinda E, Lopez-Fortuny M, Claros A, Quintana S
Acta Otolaryngol 2019 Aug;139(8):720-725. Epub 2019 Jun 1 doi: 10.1080/00016489.2019.1618913. PMID: 31155992
Structural and functional brain abnormalities in schizophrenia: A cross-sectional study at different stages of the disease.
Zhao C, Zhu J, Liu X, Pu C, Lai Y, Chen L, Yu X, Hong N
Prog Neuropsychopharmacol Biol Psychiatry 2018 Apr 20;83:27-32. Epub 2017 Dec 29 doi: 10.1016/j.pnpbp.2017.12.017. PMID: 29292241
Abnormalities of the globe.
Roy AA, Davagnanam I, Evanson J
Clin Radiol 2012 Oct;67(10):1011-22. Epub 2012 May 29 doi: 10.1016/j.crad.2012.03.006. PMID: 22647655
Orbital syndromes.
Bhatti MT
Semin Neurol 2007 Jul;27(3):269-87. doi: 10.1055/s-2007-979685. PMID: 17577868
Dysmorphology and the orbital region: a practical clinical approach.
Dollfus H, Verloes A
Surv Ophthalmol 2004 Nov-Dec;49(6):547-61. doi: 10.1016/j.survophthal.2004.08.001. PMID: 15530943

Recent systematic reviews

Gray and white matter abnormality in patients with T2DM-related cognitive dysfunction: a systemic review and meta-analysis.
Ma T, Li ZY, Yu Y, Hu B, Han Y, Ni MH, Huang YX, Chen HH, Wang W, Yan LF, Cui GB
Nutr Diabetes 2022 Aug 15;12(1):39. doi: 10.1038/s41387-022-00214-2. PMID: 35970833Free PMC Article
Sclerotherapy for low-flow vascular malformations of the orbital and periocular regions: Systematic review and meta-analysis.
De Maria L, De Sanctis P, Tollefson M, Mardini S, Garrity JA, Morris PP, Bendel E, Brinjikji W
Surv Ophthalmol 2020 Jan-Feb;65(1):41-47. Epub 2019 Aug 16 doi: 10.1016/j.survophthal.2019.08.003. PMID: 31425703
Task and resting-state fMRI studies in first-episode schizophrenia: A systematic review.
Mwansisya TE, Hu A, Li Y, Chen X, Wu G, Huang X, Lv D, Li Z, Liu C, Xue Z, Feng J, Liu Z
Schizophr Res 2017 Nov;189:9-18. Epub 2017 Mar 3 doi: 10.1016/j.schres.2017.02.026. PMID: 28268041

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