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Abnormal scrotum morphology

MedGen UID:
871397
Concept ID:
C4025895
Anatomical Abnormality
Synonym: Abnormality of the scrotum
 
HPO: HP:0000045

Definition

Any structural abnormality of the scrotum, i.e., the sac that contains the testes, epididymis, and the lower part of the spermatic cord. [from HPO]

Professional guidelines

PubMed

Elamo HP, Virtanen HE, Toppari J
Best Pract Res Clin Endocrinol Metab 2022 Jan;36(1):101619. Epub 2022 Feb 4 doi: 10.1016/j.beem.2022.101619. PMID: 35193821
Punjani N, Wald G, Al-Hussein Alawamlh O, Dudley V, Goldstein M
J Urol 2021 Oct;206(4):1001-1008. Epub 2021 May 25 doi: 10.1097/JU.0000000000001877. PMID: 34032502
Fratrić I, Šarac D, Antić J, Đermanov M, Jokić R
Biomed Res Int 2018;2018:3143412. Epub 2018 Jul 17 doi: 10.1155/2018/3143412. PMID: 30112376Free PMC Article

Recent clinical studies

Etiology

Rodprasert W, Virtanen HE, Toppari J
Front Endocrinol (Lausanne) 2024;15:1347435. Epub 2024 Mar 12 doi: 10.3389/fendo.2024.1347435. PMID: 38532895Free PMC Article
Toppari J, Rodprasert W, Virtanen HE
Ann Endocrinol (Paris) 2014 May;75(2):72-6. Epub 2014 Apr 29 doi: 10.1016/j.ando.2014.04.010. PMID: 24786701
Hughes IA, Werner R, Bunch T, Hiort O
Semin Reprod Med 2012 Oct;30(5):432-42. Epub 2012 Oct 8 doi: 10.1055/s-0032-1324728. PMID: 23044881
Hutson JM, Balic A, Nation T, Southwell B
Semin Pediatr Surg 2010 Aug;19(3):215-24. doi: 10.1053/j.sempedsurg.2010.04.001. PMID: 20610195
Toppari J, Kaleva M
Horm Res 1999 Dec;51(6):261-9. doi: 10.1159/000023412. PMID: 10640886

Diagnosis

Fitouri F, Chebil N, Ben Ammar S, Sahli S, Hamzaoui M
Fetal Pediatr Pathol 2020 Feb;39(1):90-91. Epub 2019 Jun 19 doi: 10.1080/15513815.2019.1629133. PMID: 31215294
Alkhori NA, Barth RA
Pediatr Radiol 2017 Aug;47(9):1125-1133. Epub 2017 Aug 4 doi: 10.1007/s00247-017-3923-9. PMID: 28779199
Masson P, Brannigan RE
Urol Clin North Am 2014 Feb;41(1):129-44. doi: 10.1016/j.ucl.2013.08.001. PMID: 24286772
Rubenstein RA, Dogra VS, Seftel AD, Resnick MI
J Urol 2004 May;171(5):1765-72. doi: 10.1097/01.ju.0000123083.98845.88. PMID: 15076274
Bozdağ KE, Gül Y, Karaman A
Int J Dermatol 2000 Mar;39(3):203-4. doi: 10.1046/j.1365-4362.2000.00816.x. PMID: 10759961

Therapy

Toppari J, Rodprasert W, Virtanen HE
Ann Endocrinol (Paris) 2014 May;75(2):72-6. Epub 2014 Apr 29 doi: 10.1016/j.ando.2014.04.010. PMID: 24786701
Giwercman A, Giwercman YL
Best Pract Res Clin Endocrinol Metab 2011 Apr;25(2):391-402. doi: 10.1016/j.beem.2010.09.011. PMID: 21397206
Toppari J, Kaleva M
Horm Res 1999 Dec;51(6):261-9. doi: 10.1159/000023412. PMID: 10640886
Thonneau P, Bujan L, Multigner L, Mieusset R
Hum Reprod 1998 Aug;13(8):2122-5. doi: 10.1093/humrep/13.8.2122. PMID: 9756281
Federman DD, Donahoe PK
Adv Endocrinol Metab 1995;6:91-116. PMID: 7671103

Prognosis

Mikuz G
Pathologe 2019 Jun;40(Suppl 1):1-8. doi: 10.1007/s00292-018-0505-z. PMID: 30446779
Hutson JM, Balic A, Nation T, Southwell B
Semin Pediatr Surg 2010 Aug;19(3):215-24. doi: 10.1053/j.sempedsurg.2010.04.001. PMID: 20610195
Leung AK, Robson WL
Asian J Androl 2007 Jan;9(1):16-22. doi: 10.1111/j.1745-7262.2007.00243.x. PMID: 17187155
Toppari J, Kaleva M
Horm Res 1999 Dec;51(6):261-9. doi: 10.1159/000023412. PMID: 10640886
Avellán L
Scand J Plast Reconstr Surg 1980;14(3):239-47. doi: 10.3109/02844318009106717. PMID: 7209410

Clinical prediction guides

Fitouri F, Chebil N, Ben Ammar S, Sahli S, Hamzaoui M
Fetal Pediatr Pathol 2020 Feb;39(1):90-91. Epub 2019 Jun 19 doi: 10.1080/15513815.2019.1629133. PMID: 31215294
Giwercman A, Giwercman YL
Best Pract Res Clin Endocrinol Metab 2011 Apr;25(2):391-402. doi: 10.1016/j.beem.2010.09.011. PMID: 21397206
Hutson JM, Balic A, Nation T, Southwell B
Semin Pediatr Surg 2010 Aug;19(3):215-24. doi: 10.1053/j.sempedsurg.2010.04.001. PMID: 20610195
Pham SB, Hong MK, Teague JA, Hutson JM
Pediatr Surg Int 2005 Apr;21(4):231-9. Epub 2005 Mar 9 doi: 10.1007/s00383-005-1364-2. PMID: 15756559
Toppari J, Kaleva M
Horm Res 1999 Dec;51(6):261-9. doi: 10.1159/000023412. PMID: 10640886

Recent systematic reviews

Senescende L, Bitolog PL, Auberger E, Zarzavadjian Le Bian A, Cesaretti M
Hernia 2016 Dec;20(6):879-885. Epub 2016 Sep 6 doi: 10.1007/s10029-016-1535-1. PMID: 27601037

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