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Perivascular fibrosis

MedGen UID:
87194
•Concept ID:
C0334144
•
Pathologic Function
Synonym: Perivascular Fibrosis
SNOMED CT: Perivascular fibrosis (46283004)
 
HPO: HP:0032200

Definition

The presence of thick collagen bundles around blood vessels, often in an onion-skin type whorling pattern. [from HPO]

Professional guidelines

PubMed

Heart Failure With Preserved Ejection Fraction in Diabetes: Mechanisms and Management.
Meagher P, Adam M, Civitarese R, Bugyei-Twum A, Connelly KA
Can J Cardiol 2018 May;34(5):632-643. Epub 2018 Mar 2 doi: 10.1016/j.cjca.2018.02.026. PMID: 29731023
Evaluation of subclinical target organ damage for risk assessment and treatment in the hypertensive patients: left ventricular hypertrophy.
Agabiti-Rosei E, Muiesan ML, Salvetti M
J Am Soc Nephrol 2006 Apr;17(4 Suppl 2):S104-8. doi: 10.1681/ASN.2005121336. PMID: 16565230
The impact of computed tomography in the diagnosis and postoperative follow-up of ureteric obstruction in aorto-iliac aneurysmal disease.
Nachbur B, Marincek B, Jakob R, Ackerman D
Eur J Vasc Surg 1989 Dec;3(6):475-92. doi: 10.1016/s0950-821x(89)80121-5. PMID: 2625158

Recent clinical studies

Etiology

Comparative analysis on the anti-inflammatory/immune effect of mesenchymal stem cell therapy for the treatment of pulmonary arterial hypertension.
Oh S, Jang AY, Chae S, Choi S, Moon J, Kim M, Spiekerkoetter E, Zamanian RT, Yang PC, Hwang D, Byun K, Chung WJ
Sci Rep 2021 Jan 21;11(1):2012. doi: 10.1038/s41598-021-81244-1. PMID: 33479312Free PMC Article
A review of homocysteine and heart failure.
Herrmann M, Taban-Shomal O, Hübner U, Böhm M, Herrmann W
Eur J Heart Fail 2006 Oct;8(6):571-6. Epub 2006 Feb 28 doi: 10.1016/j.ejheart.2005.11.016. PMID: 16504575
Bilateral fronto-occipital polymicrogyria and epilepsy.
Ribacoba Montero R, Garcia Pravia C, Astudillo A, Salas Puig J
Seizure 2002 Apr;11 Suppl A:298-302. PMID: 12185764
Bilateral fronto-occipital polymicrogyria and epilepsy.
Ribacoba Montero R, Garcia Pravia C, Astudillo A, Salas Puig J
Seizure 2001 Jun;10(4):298-302. doi: 10.1053/seiz.2000.0496. PMID: 11466027
Coronary microcirculation and cardiovascular pathology.
Garot P, Teiger E, Dupouy P, Aptecar E, Hittinger L, Dubois-Randé JL
Drugs 1999;59 Spec No:23-31. PMID: 10548389

Diagnosis

Cardiac fibrosis: Cell biological mechanisms, molecular pathways and therapeutic opportunities.
Frangogiannis NG
Mol Aspects Med 2019 Feb;65:70-99. Epub 2018 Aug 2 doi: 10.1016/j.mam.2018.07.001. PMID: 30056242
Histopathological aspects of cardiac biopsy in pediatric patients with dilated cardiomyopathy.
Nishikawa T, Uto K, Kanai S, Oda H, Kawamura S, Nakanishi T, Hagiwara N, Morimoto S
Pediatr Int 2011 Jun;53(3):350-3. doi: 10.1111/j.1442-200X.2010.03250.x. PMID: 20854285
Bilateral fronto-occipital polymicrogyria and epilepsy.
Ribacoba Montero R, Garcia Pravia C, Astudillo A, Salas Puig J
Seizure 2002 Apr;11 Suppl A:298-302. PMID: 12185764
Bilateral fronto-occipital polymicrogyria and epilepsy.
Ribacoba Montero R, Garcia Pravia C, Astudillo A, Salas Puig J
Seizure 2001 Jun;10(4):298-302. doi: 10.1053/seiz.2000.0496. PMID: 11466027
Coronary microcirculation and cardiovascular pathology.
Garot P, Teiger E, Dupouy P, Aptecar E, Hittinger L, Dubois-Randé JL
Drugs 1999;59 Spec No:23-31. PMID: 10548389

Therapy

Cardiac fibrosis.
Frangogiannis NG
Cardiovasc Res 2021 May 25;117(6):1450-1488. doi: 10.1093/cvr/cvaa324. PMID: 33135058Free PMC Article
Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities.
Mettu PS, Allingham MJ, Cousins SW
Prog Retin Eye Res 2021 May;82:100906. Epub 2020 Oct 3 doi: 10.1016/j.preteyeres.2020.100906. PMID: 33022379Free PMC Article
Long-Term Reduction of High Blood Pressure by Angiotensin II DNA Vaccine in Spontaneously Hypertensive Rats.
Koriyama H, Nakagami H, Nakagami F, Osako MK, Kyutoku M, Shimamura M, Kurinami H, Katsuya T, Rakugi H, Morishita R
Hypertension 2015 Jul;66(1):167-74. Epub 2015 May 26 doi: 10.1161/HYPERTENSIONAHA.114.04534. PMID: 26015450
Menopausal changes in the myometrium: an investigation using a GnRH agonist model.
Weeks AD, Wilkinson N, Arora DS, Duffy SR, Wells M, Walker JJ
Int J Gynecol Pathol 1999 Jul;18(3):226-32. doi: 10.1097/00004347-199907000-00007. PMID: 12090591
Perivascular fibrosis in prolactinomas: is it increased by bromocriptine?
Landolt AM, Osterwalder V
J Clin Endocrinol Metab 1984 Jun;58(6):1179-83. doi: 10.1210/jcem-58-6-1179. PMID: 6725514

Prognosis

Morphological and immunological markers of repeated heart remodeling after surgical reconstruction of the left ventricle in ischemic cardiomyopathy.
Shipulin VM, Andreev SL, Belyaeva SA, Pryakhin AS, Sukhodolo IV, Chumakova SP
Asian Cardiovasc Thorac Ann 2023 Mar;31(3):194-201. Epub 2023 Feb 2 doi: 10.1177/02184923231152107. PMID: 36734055
A review of homocysteine and heart failure.
Herrmann M, Taban-Shomal O, Hübner U, Böhm M, Herrmann W
Eur J Heart Fail 2006 Oct;8(6):571-6. Epub 2006 Feb 28 doi: 10.1016/j.ejheart.2005.11.016. PMID: 16504575
Bilateral fronto-occipital polymicrogyria and epilepsy.
Ribacoba Montero R, Garcia Pravia C, Astudillo A, Salas Puig J
Seizure 2002 Apr;11 Suppl A:298-302. PMID: 12185764
Bilateral fronto-occipital polymicrogyria and epilepsy.
Ribacoba Montero R, Garcia Pravia C, Astudillo A, Salas Puig J
Seizure 2001 Jun;10(4):298-302. doi: 10.1053/seiz.2000.0496. PMID: 11466027
Radiation-induced heart disease.
Stroobandt R, Knieriem H-J, De Wolf, joossens JV
Acta Cardiol 1975;30(5):383-92. PMID: 1082702

Clinical prediction guides

Endothelial Response to Type I Interferon Contributes to Vasculopathy and Fibrosis and Predicts Disease Progression of Systemic Sclerosis.
Yin H, Distler O, Shen L, Xu X, Yuan Y, Li R, Liu B, Li Q, Huang Q, Xie F, Zhang Z, Liang R, Dai X, Chen X, Li B, Yan Q, Lu L
Arthritis Rheumatol 2024 Jan;76(1):78-91. doi: 10.1002/art.42662. PMID: 37488975
Comparative analysis on the anti-inflammatory/immune effect of mesenchymal stem cell therapy for the treatment of pulmonary arterial hypertension.
Oh S, Jang AY, Chae S, Choi S, Moon J, Kim M, Spiekerkoetter E, Zamanian RT, Yang PC, Hwang D, Byun K, Chung WJ
Sci Rep 2021 Jan 21;11(1):2012. doi: 10.1038/s41598-021-81244-1. PMID: 33479312Free PMC Article
A Newly Recognized Histologic Pattern of IgG4-related Lymphadenopathy: Expanding the Morphologic Spectrum.
Chen YR, Chen YJ, Wang MC, Medeiros LJ, Chang KC
Am J Surg Pathol 2018 Jul;42(7):977-982. doi: 10.1097/PAS.0000000000001076. PMID: 29738364
Histopathological aspects of cardiac biopsy in pediatric patients with dilated cardiomyopathy.
Nishikawa T, Uto K, Kanai S, Oda H, Kawamura S, Nakanishi T, Hagiwara N, Morimoto S
Pediatr Int 2011 Jun;53(3):350-3. doi: 10.1111/j.1442-200X.2010.03250.x. PMID: 20854285
Pulmonary lesions in the course of rheumatoid arthritis in children.
Romicka A, Małdyk E
Pol Med Sci Hist Bull (1973) 1975 May-Jun;15(3):263-8. PMID: 1221374

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