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Teratoma with malignant transformation

MedGen UID:
87256
Concept ID:
C0334523
Neoplastic Process
Synonyms: Dermoid cyst with malignant transformation; Dermoid Cyst with Malignant Transformation; dermoid cyst with malignant transformation; Dermoid cyst with secondary tumor; Teratoma with Malignant Transformation; teratoma with malignant transformation; Teratoma with Somatic-Type Malignancy; TMT
SNOMED CT: Teratoma with malignant transformation (88334008); Dermoid cyst with malignant transformation (88334008); Dermoid cyst with secondary tumor (88334008)
 
Monarch Initiative: MONDO:0006444

Definition

A teratoma which is characterized by morphologic transformation to malignancy and an aggressive clinical course. The malignant component most often is sarcomatous or carcinomatous. [from NCI]

Professional guidelines

PubMed

Giannatempo P, Pond GR, Sonpavde G, Albany C, Loriot Y, Sweeney CJ, Salvioni R, Colecchia M, Nicolai N, Raggi D, Rice KR, Flack CK, El Mouallem NR, Feldman H, Fizazi K, Einhorn LH, Foster RS, Necchi A, Cary C
J Urol 2016 Jul;196(1):95-100. Epub 2015 Dec 31 doi: 10.1016/j.juro.2015.12.082. PMID: 26748165
Necchi A, Colecchia M, Nicolai N, Piva L, Catanzaro M, Biasoni D, Torelli T, Stagni S, Paolini B, Milani A, Salvioni R
BJU Int 2011 Apr;107(7):1088-94. Epub 2010 Sep 24 doi: 10.1111/j.1464-410X.2010.09705.x. PMID: 20868391
Fujimaki T
J Child Neurol 2009 Nov;24(11):1439-45. doi: 10.1177/0883073809342127. PMID: 19841431

Recent clinical studies

Etiology

Yuan Y, Li H, Yang H
Indian J Pathol Microbiol 2022 Apr-Jun;65(2):369-373. doi: 10.4103/IJPM.IJPM_828_20. PMID: 35435373
Wang X, Li W, Kong Y, Liu X, Cui Z
J Int Med Res 2021 Feb;49(2):300060520981549. doi: 10.1177/0300060520981549. PMID: 33530815Free PMC Article
Giannatempo P, Pond GR, Sonpavde G, Albany C, Loriot Y, Sweeney CJ, Salvioni R, Colecchia M, Nicolai N, Raggi D, Rice KR, Flack CK, El Mouallem NR, Feldman H, Fizazi K, Einhorn LH, Foster RS, Necchi A, Cary C
J Urol 2016 Jul;196(1):95-100. Epub 2015 Dec 31 doi: 10.1016/j.juro.2015.12.082. PMID: 26748165
Park SB, Cho KS, Kim JK
Clin Imaging 2011 Jul-Aug;35(4):294-300. doi: 10.1016/j.clinimag.2010.08.016. PMID: 21724123
Oldenburg J, Wahlqvist R, Fosså SD
World J Urol 2009 Aug;27(4):493-500. Epub 2009 Apr 17 doi: 10.1007/s00345-009-0411-3. PMID: 19373473

Diagnosis

Lee KF, Lo EYJ, Cheung SYS
Clin Gastroenterol Hepatol 2023 Oct;21(11):A23-A24. Epub 2023 Apr 8 doi: 10.1016/j.cgh.2023.03.030. PMID: 37037261
Yuan Y, Li H, Yang H
Indian J Pathol Microbiol 2022 Apr-Jun;65(2):369-373. doi: 10.4103/IJPM.IJPM_828_20. PMID: 35435373
Tehranian A, Ghahghaei-Nezamabadi A, Seifollahi A, Kasraei S, Dehghani-Nejad H, Maleki-Hajiagha A
J Med Case Rep 2021 Jan 27;15(1):23. doi: 10.1186/s13256-020-02594-4. PMID: 33499917Free PMC Article
Cabral FC, Krajewski KM, Rosenthal MH, Hirsch MS, Howard SA
Clin Imaging 2014 Sep-Oct;38(5):589-93. Epub 2014 Apr 28 doi: 10.1016/j.clinimag.2014.04.011. PMID: 24908364
Biskup W, Calaminus G, Schneider DT, Leuschner I, Göbel U
Klin Padiatr 2006 Nov-Dec;218(6):303-8. doi: 10.1055/s-2006-942272. PMID: 17080331

Therapy

Giannatempo P, Pond GR, Sonpavde G, Albany C, Loriot Y, Sweeney CJ, Salvioni R, Colecchia M, Nicolai N, Raggi D, Rice KR, Flack CK, El Mouallem NR, Feldman H, Fizazi K, Einhorn LH, Foster RS, Necchi A, Cary C
J Urol 2016 Jul;196(1):95-100. Epub 2015 Dec 31 doi: 10.1016/j.juro.2015.12.082. PMID: 26748165
Wheeler L, Westhoff GL, O'Keefe MC, Kong CS, Karam A
Int J Gynecol Pathol 2016 Jan;35(1):72-7. doi: 10.1097/PGP.0000000000000218. PMID: 26352552
Oldenburg J, Lorch A, Fosså SD
Hematol Oncol Clin North Am 2011 Jun;25(3):615-26, x. doi: 10.1016/j.hoc.2011.03.006. PMID: 21570613
Veenstra CM, Vaughn DJ
Hematol Oncol Clin North Am 2011 Jun;25(3):577-91, ix. Epub 2011 Apr 22 doi: 10.1016/j.hoc.2011.03.005. PMID: 21570610
Comiter CV, Kibel AS, Richie JP, Nucci MR, Renshaw AA
J Urol 1998 Mar;159(3):859-63. PMID: 9474169

Prognosis

Tehranian A, Ghahghaei-Nezamabadi A, Seifollahi A, Kasraei S, Dehghani-Nejad H, Maleki-Hajiagha A
J Med Case Rep 2021 Jan 27;15(1):23. doi: 10.1186/s13256-020-02594-4. PMID: 33499917Free PMC Article
Giannatempo P, Pond GR, Sonpavde G, Albany C, Loriot Y, Sweeney CJ, Salvioni R, Colecchia M, Nicolai N, Raggi D, Rice KR, Flack CK, El Mouallem NR, Feldman H, Fizazi K, Einhorn LH, Foster RS, Necchi A, Cary C
J Urol 2016 Jul;196(1):95-100. Epub 2015 Dec 31 doi: 10.1016/j.juro.2015.12.082. PMID: 26748165
Cabral FC, Krajewski KM, Rosenthal MH, Hirsch MS, Howard SA
Clin Imaging 2014 Sep-Oct;38(5):589-93. Epub 2014 Apr 28 doi: 10.1016/j.clinimag.2014.04.011. PMID: 24908364
Oldenburg J, Wahlqvist R, Fosså SD
World J Urol 2009 Aug;27(4):493-500. Epub 2009 Apr 17 doi: 10.1007/s00345-009-0411-3. PMID: 19373473
El Mesbahi O, Terrier-Lacombe MJ, Rebischung C, Theodore C, Vanel D, Fizazi K
Eur Urol 2007 May;51(5):1306-11; discussion 1311-2. Epub 2006 Oct 25 doi: 10.1016/j.eururo.2006.10.021. PMID: 17081678

Clinical prediction guides

Yuan Y, Li H, Yang H
Indian J Pathol Microbiol 2022 Apr-Jun;65(2):369-373. doi: 10.4103/IJPM.IJPM_828_20. PMID: 35435373
Giannatempo P, Pond GR, Sonpavde G, Albany C, Loriot Y, Sweeney CJ, Salvioni R, Colecchia M, Nicolai N, Raggi D, Rice KR, Flack CK, El Mouallem NR, Feldman H, Fizazi K, Einhorn LH, Foster RS, Necchi A, Cary C
J Urol 2016 Jul;196(1):95-100. Epub 2015 Dec 31 doi: 10.1016/j.juro.2015.12.082. PMID: 26748165
Hosokawa T, Sato Y, Seki T, Maebara M, Ito K, Kuribayashi S
Jpn J Radiol 2010 Jun;28(5):372-5. Epub 2010 Jun 30 doi: 10.1007/s11604-010-0434-0. PMID: 20585926
Biskup W, Calaminus G, Schneider DT, Leuschner I, Göbel U
Klin Padiatr 2006 Nov-Dec;218(6):303-8. doi: 10.1055/s-2006-942272. PMID: 17080331
Donadio AC, Motzer RJ, Bajorin DF, Kantoff PW, Sheinfeld J, Houldsworth J, Chaganti RS, Bosl GJ
J Clin Oncol 2003 Dec 1;21(23):4285-91. doi: 10.1200/JCO.2003.01.019. PMID: 14645417

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