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Neurocognitive disorder

MedGen UID:
873945
Concept ID:
C4041080
Mental or Behavioral Dysfunction
Synonyms: Disorder, Neurocognitive; Disorders, Neurocognitive; Neurocognitive Disorder; Neurocognitive Disorders
SNOMED CT: Neurocognitive disorder (709073001); Cognitive disorder due to disorder (709073001)

Definition

A disorder characterised by a decline primarily in intellectual function due to disease of the brain caused by a variety of acquired conditions such as cerebrovascular disease, Alzheimer''s disease, infections, adverse drug reactions and trauma. [from SNOMEDCT_US]

Professional guidelines

PubMed

Pérez Palmer N, Trejo Ortega B, Joshi P
Psychiatr Clin North Am 2022 Dec;45(4):639-661. Epub 2022 Oct 14 doi: 10.1016/j.psc.2022.07.010. PMID: 36396270
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K
Neurology 2017 Jul 4;89(1):88-100. Epub 2017 Jun 7 doi: 10.1212/WNL.0000000000004058. PMID: 28592453Free PMC Article
Hugo J, Ganguli M
Clin Geriatr Med 2014 Aug;30(3):421-42. Epub 2014 Jun 12 doi: 10.1016/j.cger.2014.04.001. PMID: 25037289Free PMC Article

Recent clinical studies

Etiology

Belrose JC, Noppens RR
BMC Anesthesiol 2019 Dec 27;19(1):241. doi: 10.1186/s12871-019-0903-7. PMID: 31881996Free PMC Article
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group
Br J Anaesth 2018 Nov;121(5):1005-1012. Epub 2018 Jun 15 doi: 10.1016/j.bja.2017.11.087. PMID: 30336844Free PMC Article
Jongsiriyanyong S, Limpawattana P
Am J Alzheimers Dis Other Demen 2018 Dec;33(8):500-507. Epub 2018 Aug 1 doi: 10.1177/1533317518791401. PMID: 30068225Free PMC Article
Evered LA, Silbert BS
Anesth Analg 2018 Aug;127(2):496-505. doi: 10.1213/ANE.0000000000003514. PMID: 29889707
Hugo J, Ganguli M
Clin Geriatr Med 2014 Aug;30(3):421-42. Epub 2014 Jun 12 doi: 10.1016/j.cger.2014.04.001. PMID: 25037289Free PMC Article

Diagnosis

Pérez Palmer N, Trejo Ortega B, Joshi P
Psychiatr Clin North Am 2022 Dec;45(4):639-661. Epub 2022 Oct 14 doi: 10.1016/j.psc.2022.07.010. PMID: 36396270
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group
Br J Anaesth 2018 Nov;121(5):1005-1012. Epub 2018 Jun 15 doi: 10.1016/j.bja.2017.11.087. PMID: 30336844Free PMC Article
Evered LA, Silbert BS
Anesth Analg 2018 Aug;127(2):496-505. doi: 10.1213/ANE.0000000000003514. PMID: 29889707
Gale SA, Acar D, Daffner KR
Am J Med 2018 Oct;131(10):1161-1169. Epub 2018 Feb 6 doi: 10.1016/j.amjmed.2018.01.022. PMID: 29425707
Hugo J, Ganguli M
Clin Geriatr Med 2014 Aug;30(3):421-42. Epub 2014 Jun 12 doi: 10.1016/j.cger.2014.04.001. PMID: 25037289Free PMC Article

Therapy

Karkou V, Aithal S, Richards M, Hiley E, Meekums B
Cochrane Database Syst Rev 2023 Aug 7;8(8):CD011022. doi: 10.1002/14651858.CD011022.pub3. PMID: 37549216Free PMC Article
Belrose JC, Noppens RR
BMC Anesthesiol 2019 Dec 27;19(1):241. doi: 10.1186/s12871-019-0903-7. PMID: 31881996Free PMC Article
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group
Br J Anaesth 2018 Nov;121(5):1005-1012. Epub 2018 Jun 15 doi: 10.1016/j.bja.2017.11.087. PMID: 30336844Free PMC Article
Evered LA, Silbert BS
Anesth Analg 2018 Aug;127(2):496-505. doi: 10.1213/ANE.0000000000003514. PMID: 29889707
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K
Neurology 2017 Jul 4;89(1):88-100. Epub 2017 Jun 7 doi: 10.1212/WNL.0000000000004058. PMID: 28592453Free PMC Article

Prognosis

Karkou V, Aithal S, Richards M, Hiley E, Meekums B
Cochrane Database Syst Rev 2023 Aug 7;8(8):CD011022. doi: 10.1002/14651858.CD011022.pub3. PMID: 37549216Free PMC Article
O'Gara BP, Gao L, Marcantonio ER, Subramaniam B
Anesthesiology 2021 Dec 1;135(6):1132-1152. doi: 10.1097/ALN.0000000000004046. PMID: 34731233Free PMC Article
Evered L, Silbert B, Knopman DS, Scott DA, DeKosky ST, Rasmussen LS, Oh ES, Crosby G, Berger M, Eckenhoff RG; Nomenclature Consensus Working Group
Br J Anaesth 2018 Nov;121(5):1005-1012. Epub 2018 Jun 15 doi: 10.1016/j.bja.2017.11.087. PMID: 30336844Free PMC Article
McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K
Neurology 2017 Jul 4;89(1):88-100. Epub 2017 Jun 7 doi: 10.1212/WNL.0000000000004058. PMID: 28592453Free PMC Article
Eggers C, Arendt G, Hahn K, Husstedt IW, Maschke M, Neuen-Jacob E, Obermann M, Rosenkranz T, Schielke E, Straube E; German Association of Neuro-AIDS und Neuro-Infectiology (DGNANI)
J Neurol 2017 Aug;264(8):1715-1727. Epub 2017 May 31 doi: 10.1007/s00415-017-8503-2. PMID: 28567537Free PMC Article

Clinical prediction guides

Yang L, Chen W, Yang D, Chen D, Qu Y, Hu Y, Liu D, He J, Tang Y, Zeng H, Li H, Zhang Y, Ye Z, Liu J, Li Q, Song H
JAMA Netw Open 2023 Oct 2;6(10):e2336985. doi: 10.1001/jamanetworkopen.2023.36985. PMID: 37815831Free PMC Article
O'Gara BP, Gao L, Marcantonio ER, Subramaniam B
Anesthesiology 2021 Dec 1;135(6):1132-1152. doi: 10.1097/ALN.0000000000004046. PMID: 34731233Free PMC Article
Davis JJ, Fournakis N, Ellison J
J Geriatr Psychiatry Neurol 2021 Jan;34(1):3-10. Epub 2020 Jan 30 doi: 10.1177/0891988720901785. PMID: 31996078
Belrose JC, Noppens RR
BMC Anesthesiol 2019 Dec 27;19(1):241. doi: 10.1186/s12871-019-0903-7. PMID: 31881996Free PMC Article
Mahendran R, Gandhi M, Moorakonda RB, Wong J, Kanchi MM, Fam J, Rawtaer I, Kumar AP, Feng L, Kua EH
Trials 2018 Nov 9;19(1):615. doi: 10.1186/s13063-018-2988-6. PMID: 30413216Free PMC Article

Recent systematic reviews

Duval GT, Raud E, Gohier H, Dramé M, Tabue-Teguo M, Annweiler C
Maturitas 2024 Jul;185:107866. Epub 2023 Nov 2 doi: 10.1016/j.maturitas.2023.107866. PMID: 38604094
Karkou V, Aithal S, Richards M, Hiley E, Meekums B
Cochrane Database Syst Rev 2023 Aug 7;8(8):CD011022. doi: 10.1002/14651858.CD011022.pub3. PMID: 37549216Free PMC Article
Festari C, Massa F, Cotta Ramusino M, Gandolfo F, Nicolosi V, Orini S, Aarsland D, Agosta F, Babiloni C, Boada M, Borroni B, Cappa S, Dubois B, Frederiksen KS, Froelich L, Garibotto V, Georges J, Haliassos A, Hansson O, Jessen F, Kamondi A, Kessels RPC, Morbelli S, O'Brien JT, Otto M, Perret-Liaudet A, Pizzini FB, Ritchie CW, Scheltens P, Vandenbulcke M, Vanninen R, Verhey F, Vernooij MW, Yousry T, Van Der Flier WM, Nobili F, Frisoni GB
Alzheimers Dement 2023 May;19(5):1729-1741. Epub 2022 Oct 9 doi: 10.1002/alz.12798. PMID: 36209379
Guay-Gagnon M, Vat S, Forget MF, Tremblay-Gravel M, Ducharme S, Nguyen QD, Desmarais P
J Sleep Res 2022 Oct;31(5):e13589. Epub 2022 Apr 2 doi: 10.1111/jsr.13589. PMID: 35366021
Gates NJ, Vernooij RW, Di Nisio M, Karim S, March E, Martínez G, Rutjes AW
Cochrane Database Syst Rev 2019 Mar 13;3(3):CD012279. doi: 10.1002/14651858.CD012279.pub2. PMID: 30864747Free PMC Article

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