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Long Term Adverse Effects

MedGen UID:
875662
•Concept ID:
C4042798
•
Pathologic Function
Synonym: Adverse Effects, Long Term

Definition

Persistent detrimental effects from treatment for a condition. Included are effects from surgery such as POSTOPERATIVE COMPLICATIONS, and from DRUG THERAPY, such as CHEMICALLY INDUCED DISORDERS, or other THERAPEUTICS. Failure to attain a desired outcome from treatment for the condition is not considered an adverse effect. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLong Term Adverse Effects

Professional guidelines

PubMed

Neonatal Hyperbilirubinemia: Evaluation and Treatment.
Par EJ, Hughes CA, DeRico P
Am Fam Physician 2023 May;107(5):525-534. PMID: 37192079
Update on diagnosis and treatment of immune thrombocytopenia.
Sandal R, Mishra K, Jandial A, Sahu KK, Siddiqui AD
Expert Rev Clin Pharmacol 2021 May;14(5):553-568. Epub 2021 Mar 30 doi: 10.1080/17512433.2021.1903315. PMID: 33724124
Hirschsprung's disease: diagnosis and management.
Kessmann J
Am Fam Physician 2006 Oct 15;74(8):1319-22. PMID: 17087425

Recent clinical studies

Etiology

Long-term side effects and lingering symptoms post COVID-19 recovery.
Zarei M, Bose D, Nouri-Vaskeh M, Tajiknia V, Zand R, Ghasemi M
Rev Med Virol 2022 May;32(3):e2289. Epub 2021 Sep 9 doi: 10.1002/rmv.2289. PMID: 34499784Free PMC Article
Proton Pump Inhibitor-Related Gastric Mucosal Changes.
Kim GH
Gut Liver 2021 Sep 15;15(5):646-652. doi: 10.5009/gnl20036. PMID: 32327613Free PMC Article
Management of HIV-infected patients in the intensive care unit.
Barbier F, Mer M, Szychowiak P, Miller RF, Mariotte É, Galicier L, Bouadma L, Tattevin P, Azoulay É
Intensive Care Med 2020 Feb;46(2):329-342. Epub 2020 Feb 3 doi: 10.1007/s00134-020-05945-3. PMID: 32016535Free PMC Article
Duration of Androgen Deprivation Therapy in High-risk Prostate Cancer: A Randomized Phase III Trial.
Nabid A, Carrier N, Martin AG, Bahary JP, Lemaire C, Vass S, Bahoric B, Archambault R, Vincent F, Bettahar R, Duclos M, Garant MP, Souhami L
Eur Urol 2018 Oct;74(4):432-441. Epub 2018 Jul 3 doi: 10.1016/j.eururo.2018.06.018. PMID: 29980331
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132

Diagnosis

Insomnia.
Kutscher S, Juang C
Continuum (Minneap Minn) 2023 Aug 1;29(4):1167-1187. doi: 10.1212/CON.0000000000001283. PMID: 37590828
Long-term Safety and Efficacy of Etrasimod for Ulcerative Colitis: Results from the Open-label Extension of the OASIS Study.
Vermeire S, Chiorean M, Panés J, Peyrin-Biroulet L, Zhang J, Sands BE, Lazin K, Klassen P, Naik SU, Cabell CH, Sandborn WJ
J Crohns Colitis 2021 Jun 22;15(6):950-959. doi: 10.1093/ecco-jcc/jjab016. PMID: 33475734Free PMC Article
Duration of Androgen Deprivation Therapy in High-risk Prostate Cancer: A Randomized Phase III Trial.
Nabid A, Carrier N, Martin AG, Bahary JP, Lemaire C, Vass S, Bahoric B, Archambault R, Vincent F, Bettahar R, Duclos M, Garant MP, Souhami L
Eur Urol 2018 Oct;74(4):432-441. Epub 2018 Jul 3 doi: 10.1016/j.eururo.2018.06.018. PMID: 29980331
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132
Hirschsprung's disease: diagnosis and management.
Kessmann J
Am Fam Physician 2006 Oct 15;74(8):1319-22. PMID: 17087425

Therapy

Long-term Safety and Efficacy of Etrasimod for Ulcerative Colitis: Results from the Open-label Extension of the OASIS Study.
Vermeire S, Chiorean M, Panés J, Peyrin-Biroulet L, Zhang J, Sands BE, Lazin K, Klassen P, Naik SU, Cabell CH, Sandborn WJ
J Crohns Colitis 2021 Jun 22;15(6):950-959. doi: 10.1093/ecco-jcc/jjab016. PMID: 33475734Free PMC Article
Duration of Androgen Deprivation Therapy in High-risk Prostate Cancer: A Randomized Phase III Trial.
Nabid A, Carrier N, Martin AG, Bahary JP, Lemaire C, Vass S, Bahoric B, Archambault R, Vincent F, Bettahar R, Duclos M, Garant MP, Souhami L
Eur Urol 2018 Oct;74(4):432-441. Epub 2018 Jul 3 doi: 10.1016/j.eururo.2018.06.018. PMID: 29980331
Long-term adverse effects of paracetamol - a review.
McCrae JC, Morrison EE, MacIntyre IM, Dear JW, Webb DJ
Br J Clin Pharmacol 2018 Oct;84(10):2218-2230. Epub 2018 Jul 20 doi: 10.1111/bcp.13656. PMID: 29863746Free PMC Article
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132
Pharmacokinetics and pharmacodynamics of cannabinoids.
Grotenhermen F
Clin Pharmacokinet 2003;42(4):327-60. doi: 10.2165/00003088-200342040-00003. PMID: 12648025

Prognosis

Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Cappell KM, Sherry RM, Yang JC, Goff SL, Vanasse DA, McIntyre L, Rosenberg SA, Kochenderfer JN
J Clin Oncol 2020 Nov 10;38(32):3805-3815. Epub 2020 Oct 6 doi: 10.1200/JCO.20.01467. PMID: 33021872Free PMC Article
Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
Berentsen S, Barcellini W, D'Sa S, Randen U, Tvedt THA, Fattizzo B, Haukås E, Kell M, Brudevold R, Dahm AEA, Dalgaard J, Frøen H, Hallstensen RF, Jæger PH, Hjorth-Hansen H, Małecka A, Oksman M, Rolke J, Sekhar M, Sørbø JH, Tjønnfjord E, Tsykunova G, Tjønnfjord GE
Blood 2020 Jul 23;136(4):480-488. doi: 10.1182/blood.2020005674. PMID: 32374875
Management of HIV-infected patients in the intensive care unit.
Barbier F, Mer M, Szychowiak P, Miller RF, Mariotte É, Galicier L, Bouadma L, Tattevin P, Azoulay É
Intensive Care Med 2020 Feb;46(2):329-342. Epub 2020 Feb 3 doi: 10.1007/s00134-020-05945-3. PMID: 32016535Free PMC Article
Duration of Androgen Deprivation Therapy in High-risk Prostate Cancer: A Randomized Phase III Trial.
Nabid A, Carrier N, Martin AG, Bahary JP, Lemaire C, Vass S, Bahoric B, Archambault R, Vincent F, Bettahar R, Duclos M, Garant MP, Souhami L
Eur Urol 2018 Oct;74(4):432-441. Epub 2018 Jul 3 doi: 10.1016/j.eururo.2018.06.018. PMID: 29980331
Long-term adverse effects of paracetamol - a review.
McCrae JC, Morrison EE, MacIntyre IM, Dear JW, Webb DJ
Br J Clin Pharmacol 2018 Oct;84(10):2218-2230. Epub 2018 Jul 20 doi: 10.1111/bcp.13656. PMID: 29863746Free PMC Article

Clinical prediction guides

Systematic review of the long-term effects of postnatal corticosteroids.
Jenkinson AC, Kaltsogianni O, Dassios T, Greenough A
J Perinat Med 2023 Nov 27;51(9):1120-1128. Epub 2023 Aug 23 doi: 10.1515/jpm-2023-0297. PMID: 37606507
Sustained efficacy of kangaroo care for repeated painful procedures over neonatal intensive care unit hospitalization: a single-blind randomized controlled trial.
Campbell-Yeo M, Johnston CC, Benoit B, Disher T, Caddell K, Vincer M, Walker CD, Latimer M, Streiner DL, Inglis D
Pain 2019 Nov;160(11):2580-2588. doi: 10.1097/j.pain.0000000000001646. PMID: 31356452
Duration of Androgen Deprivation Therapy in High-risk Prostate Cancer: A Randomized Phase III Trial.
Nabid A, Carrier N, Martin AG, Bahary JP, Lemaire C, Vass S, Bahoric B, Archambault R, Vincent F, Bettahar R, Duclos M, Garant MP, Souhami L
Eur Urol 2018 Oct;74(4):432-441. Epub 2018 Jul 3 doi: 10.1016/j.eururo.2018.06.018. PMID: 29980331
Long-term adverse effects of paracetamol - a review.
McCrae JC, Morrison EE, MacIntyre IM, Dear JW, Webb DJ
Br J Clin Pharmacol 2018 Oct;84(10):2218-2230. Epub 2018 Jul 20 doi: 10.1111/bcp.13656. PMID: 29863746Free PMC Article
The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis.
Juvet LK, Thune I, Elvsaas IKØ, Fors EA, Lundgren S, Bertheussen G, Leivseth G, Oldervoll LM
Breast 2017 Jun;33:166-177. Epub 2017 Apr 14 doi: 10.1016/j.breast.2017.04.003. PMID: 28415013

Recent systematic reviews

Efficacy and tolerability of pharmacological treatments for insomnia in adults: A systematic review and network meta-analysis.
Yue JL, Chang XW, Zheng JW, Shi L, Xiang YJ, Que JY, Yuan K, Deng JH, Teng T, Li YY, Sun W, Sun HQ, Vitiello MV, Tang XD, Zhou XY, Bao YP, Shi J, Lu L
Sleep Med Rev 2023 Apr;68:101746. Epub 2023 Jan 14 doi: 10.1016/j.smrv.2023.101746. PMID: 36701954
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132
Lifestyle interventions for the treatment of women with gestational diabetes.
Brown J, Alwan NA, West J, Brown S, McKinlay CJ, Farrar D, Crowther CA
Cochrane Database Syst Rev 2017 May 4;5(5):CD011970. doi: 10.1002/14651858.CD011970.pub2. PMID: 28472859Free PMC Article
The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis.
Juvet LK, Thune I, Elvsaas IKØ, Fors EA, Lundgren S, Bertheussen G, Leivseth G, Oldervoll LM
Breast 2017 Jun;33:166-177. Epub 2017 Apr 14 doi: 10.1016/j.breast.2017.04.003. PMID: 28415013
Lifestyle Intervention in Gastroesophageal Reflux Disease.
Ness-Jensen E, Hveem K, El-Serag H, Lagergren J
Clin Gastroenterol Hepatol 2016 Feb;14(2):175-82.e1-3. Epub 2015 May 6 doi: 10.1016/j.cgh.2015.04.176. PMID: 25956834Free PMC Article

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