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Long Term Adverse Effects

MedGen UID:
875662
•Concept ID:
C4042798
•
Pathologic Function
Synonym: Adverse Effects, Long Term

Definition

Persistent detrimental effects from treatment for a condition. Included are effects from surgery such as POSTOPERATIVE COMPLICATIONS, and from DRUG THERAPY, such as CHEMICALLY INDUCED DISORDERS, or other THERAPEUTICS. Failure to attain a desired outcome from treatment for the condition is not considered an adverse effect. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLong Term Adverse Effects

Professional guidelines

PubMed

Update on diagnosis and treatment of immune thrombocytopenia.
Sandal R, Mishra K, Jandial A, Sahu KK, Siddiqui AD
Expert Rev Clin Pharmacol 2021 May;14(5):553-568. Epub 2021 Mar 30 doi: 10.1080/17512433.2021.1903315. PMID: 33724124
The HELLP syndrome: clinical issues and management. A Review.
Haram K, Svendsen E, Abildgaard U
BMC Pregnancy Childbirth 2009 Feb 26;9:8. doi: 10.1186/1471-2393-9-8. PMID: 19245695Free PMC Article
Hirschsprung's disease: diagnosis and management.
Kessmann J
Am Fam Physician 2006 Oct 15;74(8):1319-22. PMID: 17087425

Recent clinical studies

Etiology

Long-term side effects and lingering symptoms post COVID-19 recovery.
Zarei M, Bose D, Nouri-Vaskeh M, Tajiknia V, Zand R, Ghasemi M
Rev Med Virol 2022 May;32(3):e2289. Epub 2021 Sep 9 doi: 10.1002/rmv.2289. PMID: 34499784Free PMC Article
Proton Pump Inhibitor-Related Gastric Mucosal Changes.
Kim GH
Gut Liver 2021 Sep 15;15(5):646-652. doi: 10.5009/gnl20036. PMID: 32327613Free PMC Article
Management of HIV-infected patients in the intensive care unit.
Barbier F, Mer M, Szychowiak P, Miller RF, Mariotte É, Galicier L, Bouadma L, Tattevin P, Azoulay É
Intensive Care Med 2020 Feb;46(2):329-342. Epub 2020 Feb 3 doi: 10.1007/s00134-020-05945-3. PMID: 32016535Free PMC Article
Hyperglycemia in Extremely Preterm Infants.
Ramel S, Rao R
Neoreviews 2020 Feb;21(2):e89-e97. doi: 10.1542/neo.21-2-e89. PMID: 32005719
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132

Diagnosis

Delirium and long term cognition in critically ill patients.
Wilcox ME, Girard TD, Hough CL
BMJ 2021 Jun 8;373:n1007. doi: 10.1136/bmj.n1007. PMID: 34103334
Long-term Safety and Efficacy of Etrasimod for Ulcerative Colitis: Results from the Open-label Extension of the OASIS Study.
Vermeire S, Chiorean M, Panés J, Peyrin-Biroulet L, Zhang J, Sands BE, Lazin K, Klassen P, Naik SU, Cabell CH, Sandborn WJ
J Crohns Colitis 2021 Jun 22;15(6):950-959. doi: 10.1093/ecco-jcc/jjab016. PMID: 33475734Free PMC Article
Lennox-Gastaut syndrome: a comprehensive review.
Asadi-Pooya AA
Neurol Sci 2018 Mar;39(3):403-414. Epub 2017 Nov 9 doi: 10.1007/s10072-017-3188-y. PMID: 29124439
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132
Hirschsprung's disease: diagnosis and management.
Kessmann J
Am Fam Physician 2006 Oct 15;74(8):1319-22. PMID: 17087425

Therapy

Proton Pump Inhibitor-Related Gastric Mucosal Changes.
Kim GH
Gut Liver 2021 Sep 15;15(5):646-652. doi: 10.5009/gnl20036. PMID: 32327613Free PMC Article
Demystifying Cannabis: A Review of Its Pharmacology, Use in Pain, and Safety Concerns.
Dume R, Lammers E
Orthop Nurs 2020 Jul/Aug;39(4):264-267. doi: 10.1097/NOR.0000000000000679. PMID: 32701785
Hyperglycemia in Extremely Preterm Infants.
Ramel S, Rao R
Neoreviews 2020 Feb;21(2):e89-e97. doi: 10.1542/neo.21-2-e89. PMID: 32005719
Long-term adverse effects of paracetamol - a review.
McCrae JC, Morrison EE, MacIntyre IM, Dear JW, Webb DJ
Br J Clin Pharmacol 2018 Oct;84(10):2218-2230. Epub 2018 Jul 20 doi: 10.1111/bcp.13656. PMID: 29863746Free PMC Article
Pharmacokinetics and pharmacodynamics of cannabinoids.
Grotenhermen F
Clin Pharmacokinet 2003;42(4):327-60. doi: 10.2165/00003088-200342040-00003. PMID: 12648025

Prognosis

Long-Term Follow-Up of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy.
Cappell KM, Sherry RM, Yang JC, Goff SL, Vanasse DA, McIntyre L, Rosenberg SA, Kochenderfer JN
J Clin Oncol 2020 Nov 10;38(32):3805-3815. Epub 2020 Oct 6 doi: 10.1200/JCO.20.01467. PMID: 33021872Free PMC Article
Cold agglutinin disease revisited: a multinational, observational study of 232 patients.
Berentsen S, Barcellini W, D'Sa S, Randen U, Tvedt THA, Fattizzo B, Haukås E, Kell M, Brudevold R, Dahm AEA, Dalgaard J, Frøen H, Hallstensen RF, Jæger PH, Hjorth-Hansen H, Małecka A, Oksman M, Rolke J, Sekhar M, Sørbø JH, Tjønnfjord E, Tsykunova G, Tjønnfjord GE
Blood 2020 Jul 23;136(4):480-488. doi: 10.1182/blood.2020005674. PMID: 32374875
Long-term nutritional follow-up post bariatric surgery.
Montastier E, Chalret du Rieu M, Tuyeras G, Ritz P
Curr Opin Clin Nutr Metab Care 2018 Sep;21(5):388-393. doi: 10.1097/MCO.0000000000000490. PMID: 29979242
Long-term adverse effects of paracetamol - a review.
McCrae JC, Morrison EE, MacIntyre IM, Dear JW, Webb DJ
Br J Clin Pharmacol 2018 Oct;84(10):2218-2230. Epub 2018 Jul 20 doi: 10.1111/bcp.13656. PMID: 29863746Free PMC Article
The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis.
Juvet LK, Thune I, Elvsaas IKØ, Fors EA, Lundgren S, Bertheussen G, Leivseth G, Oldervoll LM
Breast 2017 Jun;33:166-177. Epub 2017 Apr 14 doi: 10.1016/j.breast.2017.04.003. PMID: 28415013

Clinical prediction guides

Duration of Androgen Deprivation Therapy in High-risk Prostate Cancer: A Randomized Phase III Trial.
Nabid A, Carrier N, Martin AG, Bahary JP, Lemaire C, Vass S, Bahoric B, Archambault R, Vincent F, Bettahar R, Duclos M, Garant MP, Souhami L
Eur Urol 2018 Oct;74(4):432-441. Epub 2018 Jul 3 doi: 10.1016/j.eururo.2018.06.018. PMID: 29980331
Long-term adverse effects of paracetamol - a review.
McCrae JC, Morrison EE, MacIntyre IM, Dear JW, Webb DJ
Br J Clin Pharmacol 2018 Oct;84(10):2218-2230. Epub 2018 Jul 20 doi: 10.1111/bcp.13656. PMID: 29863746Free PMC Article
The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis.
Juvet LK, Thune I, Elvsaas IKØ, Fors EA, Lundgren S, Bertheussen G, Leivseth G, Oldervoll LM
Breast 2017 Jun;33:166-177. Epub 2017 Apr 14 doi: 10.1016/j.breast.2017.04.003. PMID: 28415013
Long-Term Adverse Effects of Early Growth Acceleration or Catch-Up Growth.
Singhal A
Ann Nutr Metab 2017;70(3):236-240. Epub 2017 Mar 17 doi: 10.1159/000464302. PMID: 28301849
Lifestyle Intervention in Gastroesophageal Reflux Disease.
Ness-Jensen E, Hveem K, El-Serag H, Lagergren J
Clin Gastroenterol Hepatol 2016 Feb;14(2):175-82.e1-3. Epub 2015 May 6 doi: 10.1016/j.cgh.2015.04.176. PMID: 25956834Free PMC Article

Recent systematic reviews

Efficacy and tolerability of pharmacological treatments for insomnia in adults: A systematic review and network meta-analysis.
Yue JL, Chang XW, Zheng JW, Shi L, Xiang YJ, Que JY, Yuan K, Deng JH, Teng T, Li YY, Sun W, Sun HQ, Vitiello MV, Tang XD, Zhou XY, Bao YP, Shi J, Lu L
Sleep Med Rev 2023 Apr;68:101746. Epub 2023 Jan 14 doi: 10.1016/j.smrv.2023.101746. PMID: 36701954
Systematic review on long-term adverse effects of inhaled corticosteroids in the treatment of COPD.
Miravitlles M, Auladell-Rispau A, Monteagudo M, Vázquez-Niebla JC, Mohammed J, Nuñez A, Urrútia G
Eur Respir Rev 2021 Jun 30;30(160) Epub 2021 Jun 23 doi: 10.1183/16000617.0075-2021. PMID: 34168063Free PMC Article
Side-effects associated with ketamine use in depression: a systematic review.
Short B, Fong J, Galvez V, Shelker W, Loo CK
Lancet Psychiatry 2018 Jan;5(1):65-78. Epub 2017 Jul 27 doi: 10.1016/S2215-0366(17)30272-9. PMID: 28757132
The effect of exercise on fatigue and physical functioning in breast cancer patients during and after treatment and at 6 months follow-up: A meta-analysis.
Juvet LK, Thune I, Elvsaas IKØ, Fors EA, Lundgren S, Bertheussen G, Leivseth G, Oldervoll LM
Breast 2017 Jun;33:166-177. Epub 2017 Apr 14 doi: 10.1016/j.breast.2017.04.003. PMID: 28415013
Lifestyle Intervention in Gastroesophageal Reflux Disease.
Ness-Jensen E, Hveem K, El-Serag H, Lagergren J
Clin Gastroenterol Hepatol 2016 Feb;14(2):175-82.e1-3. Epub 2015 May 6 doi: 10.1016/j.cgh.2015.04.176. PMID: 25956834Free PMC Article

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