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Colon perforation

MedGen UID:
87582
•Concept ID:
C0347646
•
Disease or Syndrome
Synonyms: Colonic Perforation; Colonic perforation; Perforation of colon; Perforation of the colon
SNOMED CT: Perforation of colon (50257008); Colonic perforation (50257008)
 
HPO: HP:0031369

Definition

A hole (perforation) in the wall of the colon. [from HPO]

Conditions with this feature

Pancreatic hypoplasia-diabetes-congenital heart disease syndrome
MedGen UID:
860891
•Concept ID:
C4012454
•
Congenital Abnormality
A rare, syndromic diabetes mellitus characterized by partial pancreatic agenesis, diabetes mellitus, and heart anomalies (including transposition of the great vessels, ventricular or atrial septal defects, pulmonary stenosis, or patent ductus arteriosis).
See: Condition Record
Pancreatic hypoplasia-diabetes-congenital heart disease syndrome

Professional guidelines

PubMed

Laparoscopic management of iatrogenic colon perforation.
Loberman B, Kuhnreich E, Matter I, Sroka G
Int J Colorectal Dis 2023 Oct 27;38(1):259. doi: 10.1007/s00384-023-04550-2. PMID: 37889340
Antipsychotic-Induced Constipation: A Review of the Pathogenesis, Clinical Diagnosis, and Treatment.
Xu Y, Amdanee N, Zhang X
CNS Drugs 2021 Dec;35(12):1265-1274. Epub 2021 Aug 24 doi: 10.1007/s40263-021-00859-0. PMID: 34427901
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review.
Lee JH, Kedia P, Stavropoulos SN, Carr-Locke D
Clin Gastroenterol Hepatol 2021 Nov;19(11):2252-2261.e2. Epub 2021 Jul 2 doi: 10.1016/j.cgh.2021.06.045. PMID: 34224876

Recent clinical studies

Etiology

AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review.
Lee JH, Kedia P, Stavropoulos SN, Carr-Locke D
Clin Gastroenterol Hepatol 2021 Nov;19(11):2252-2261.e2. Epub 2021 Jul 2 doi: 10.1016/j.cgh.2021.06.045. PMID: 34224876
Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L)1 monotherapy: a multicentre, retrospective, cohort study.
Pires da Silva I, Ahmed T, Reijers ILM, Weppler AM, Betof Warner A, Patrinely JR, Serra-Bellver P, Allayous C, Mangana J, Nguyen K, Zimmer L, Trojaniello C, Stout D, Lyle M, Klein O, Gerard CL, Michielin O, Haydon A, Ascierto PA, Carlino MS, Lebbe C, Lorigan P, Johnson DB, Sandhu S, Lo SN, Blank CU, Menzies AM, Long GV
Lancet Oncol 2021 Jun;22(6):836-847. Epub 2021 May 11 doi: 10.1016/S1470-2045(21)00097-8. PMID: 33989557
Adverse events related to colonoscopy: Global trends and future challenges.
Kim SY, Kim HS, Park HJ
World J Gastroenterol 2019 Jan 14;25(2):190-204. doi: 10.3748/wjg.v25.i2.190. PMID: 30670909Free PMC Article
Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial.
Hodi FS, Chiarion-Sileni V, Gonzalez R, Grob JJ, Rutkowski P, Cowey CL, Lao CD, Schadendorf D, Wagstaff J, Dummer R, Ferrucci PF, Smylie M, Hill A, Hogg D, Marquez-Rodas I, Jiang J, Rizzo J, Larkin J, Wolchok JD
Lancet Oncol 2018 Nov;19(11):1480-1492. Epub 2018 Oct 22 doi: 10.1016/S1470-2045(18)30700-9. PMID: 30361170
Adverse effects of herbal medicines: an overview of systematic reviews.
Posadzki P, Watson LK, Ernst E
Clin Med (Lond) 2013 Feb;13(1):7-12. doi: 10.7861/clinmedicine.13-1-7. PMID: 23472485Free PMC Article

Diagnosis

Development of diaphragmatic hernia following hepatectomy.
Kara S, Korkut E, Aksungur N, Altundas N, Ozturk G
ANZ J Surg 2022 Sep;92(9):2163-2166. Epub 2022 Aug 3 doi: 10.1111/ans.17942. PMID: 35921390
Antipsychotic-Induced Constipation: A Review of the Pathogenesis, Clinical Diagnosis, and Treatment.
Xu Y, Amdanee N, Zhang X
CNS Drugs 2021 Dec;35(12):1265-1274. Epub 2021 Aug 24 doi: 10.1007/s40263-021-00859-0. PMID: 34427901
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review.
Lee JH, Kedia P, Stavropoulos SN, Carr-Locke D
Clin Gastroenterol Hepatol 2021 Nov;19(11):2252-2261.e2. Epub 2021 Jul 2 doi: 10.1016/j.cgh.2021.06.045. PMID: 34224876
Adverse events related to colonoscopy: Global trends and future challenges.
Kim SY, Kim HS, Park HJ
World J Gastroenterol 2019 Jan 14;25(2):190-204. doi: 10.3748/wjg.v25.i2.190. PMID: 30670909Free PMC Article
Small bowel and colon perforation.
Brown CV
Surg Clin North Am 2014 Apr;94(2):471-5. doi: 10.1016/j.suc.2014.01.010. PMID: 24679432

Therapy

Antipsychotic-Induced Constipation: A Review of the Pathogenesis, Clinical Diagnosis, and Treatment.
Xu Y, Amdanee N, Zhang X
CNS Drugs 2021 Dec;35(12):1265-1274. Epub 2021 Aug 24 doi: 10.1007/s40263-021-00859-0. PMID: 34427901
Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L)1 monotherapy: a multicentre, retrospective, cohort study.
Pires da Silva I, Ahmed T, Reijers ILM, Weppler AM, Betof Warner A, Patrinely JR, Serra-Bellver P, Allayous C, Mangana J, Nguyen K, Zimmer L, Trojaniello C, Stout D, Lyle M, Klein O, Gerard CL, Michielin O, Haydon A, Ascierto PA, Carlino MS, Lebbe C, Lorigan P, Johnson DB, Sandhu S, Lo SN, Blank CU, Menzies AM, Long GV
Lancet Oncol 2021 Jun;22(6):836-847. Epub 2021 May 11 doi: 10.1016/S1470-2045(21)00097-8. PMID: 33989557
Adverse events related to colonoscopy: Global trends and future challenges.
Kim SY, Kim HS, Park HJ
World J Gastroenterol 2019 Jan 14;25(2):190-204. doi: 10.3748/wjg.v25.i2.190. PMID: 30670909Free PMC Article
Nivolumab plus ipilimumab or nivolumab alone versus ipilimumab alone in advanced melanoma (CheckMate 067): 4-year outcomes of a multicentre, randomised, phase 3 trial.
Hodi FS, Chiarion-Sileni V, Gonzalez R, Grob JJ, Rutkowski P, Cowey CL, Lao CD, Schadendorf D, Wagstaff J, Dummer R, Ferrucci PF, Smylie M, Hill A, Hogg D, Marquez-Rodas I, Jiang J, Rizzo J, Larkin J, Wolchok JD
Lancet Oncol 2018 Nov;19(11):1480-1492. Epub 2018 Oct 22 doi: 10.1016/S1470-2045(18)30700-9. PMID: 30361170
Adverse effects of herbal medicines: an overview of systematic reviews.
Posadzki P, Watson LK, Ernst E
Clin Med (Lond) 2013 Feb;13(1):7-12. doi: 10.7861/clinmedicine.13-1-7. PMID: 23472485Free PMC Article

Prognosis

Development of diaphragmatic hernia following hepatectomy.
Kara S, Korkut E, Aksungur N, Altundas N, Ozturk G
ANZ J Surg 2022 Sep;92(9):2163-2166. Epub 2022 Aug 3 doi: 10.1111/ans.17942. PMID: 35921390
Colon Perforation by Compressed Air: A Case Report and Short Review of Literature.
Das S, Hanuman SB, Toi PC, Subramania DB, Yanamadala SP
Am J Forensic Med Pathol 2019 Dec;40(4):376-380. doi: 10.1097/PAF.0000000000000499. PMID: 31306168
Adverse events related to colonoscopy: Global trends and future challenges.
Kim SY, Kim HS, Park HJ
World J Gastroenterol 2019 Jan 14;25(2):190-204. doi: 10.3748/wjg.v25.i2.190. PMID: 30670909Free PMC Article
Outcome of colon cancer initially presenting as colon perforation and obstruction.
Chen TM, Huang YT, Wang GC
World J Surg Oncol 2017 Aug 25;15(1):164. doi: 10.1186/s12957-017-1228-y. PMID: 28841901Free PMC Article
Secondary peritonitis - evaluation of 204 cases and literature review.
Doklestić SK, Bajec DD, Djukić RV, Bumbaširević V, Detanac AD, Detanac SD, Bracanović M, Karamarković RA
J Med Life 2014 Jun 15;7(2):132-8. Epub 2014 Jun 25 PMID: 25408716Free PMC Article

Clinical prediction guides

Coexistence of Colon Perforation and Congenital Lipodystrophy.
Acar N, Acar T, Suataman B, Ekinci N, Tatar F
J Coll Physicians Surg Pak 2022 Sep;32(9):1222-1224. doi: 10.29271/jcpsp.2022.09.1222. PMID: 36089727
Sigmoid colon perforation in a SARS-CoV-2 positive neonate: a uniqueness report and a brief review.
Jamali Z, Sinaei R, Estabragh ER, Ahangaran A
BMC Pediatr 2022 Jun 3;22(1):327. doi: 10.1186/s12887-022-03392-1. PMID: 35659271Free PMC Article
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review.
Lee JH, Kedia P, Stavropoulos SN, Carr-Locke D
Clin Gastroenterol Hepatol 2021 Nov;19(11):2252-2261.e2. Epub 2021 Jul 2 doi: 10.1016/j.cgh.2021.06.045. PMID: 34224876
Endoscopic features and clinical outcomes of cytomegalovirus gastroenterocolitis in immunocompetent patients.
Yoon J, Lee J, Kim DS, Lee JW, Hong SW, Hwang HW, Hwang SW, Park SH, Yang DH, Ye BD, Myung SJ, Jung HY, Yang SK, Byeon JS
Sci Rep 2021 Mar 18;11(1):6284. doi: 10.1038/s41598-021-85845-8. PMID: 33737711Free PMC Article
Outcome of colon cancer initially presenting as colon perforation and obstruction.
Chen TM, Huang YT, Wang GC
World J Surg Oncol 2017 Aug 25;15(1):164. doi: 10.1186/s12957-017-1228-y. PMID: 28841901Free PMC Article

Recent systematic reviews

The impact of abdominal compression devices on colonoscopy outcomes: a systematic review and meta-analysis of randomized controlled trials.
Abuelazm MT, Abdelnabi M, Mahmoud A, Albarakat MM, Mohamed I, Saeed A, Gowaily I, Abdelazeem B
Curr Med Res Opin 2023 Sep;39(9):1247-1256. Epub 2023 Aug 18 doi: 10.1080/03007995.2023.2243214. PMID: 37526014
Mesenchymal Stromal Cells for Enhancing Hematopoietic Engraftment and Treatment of Graft-Versus-Host Disease, Hemorrhages and Acute Respiratory Distress Syndrome.
Ringdén O, Moll G, Gustafsson B, Sadeghi B
Front Immunol 2022;13:839844. Epub 2022 Mar 18 doi: 10.3389/fimmu.2022.839844. PMID: 35371003Free PMC Article
Fatal Case of Perforated Cytomegalovirus Colitis: Case Report and Systematic Review.
Fisher AT, Bessoff KE, Nicholas V, Badger J, Knowlton L, Forrester JD
Surg Infect (Larchmt) 2022 Mar;23(2):127-134. Epub 2021 Dec 2 doi: 10.1089/sur.2021.173. PMID: 34860604
Endoscopic treatment of colorectal perforations--a systematic review.
Hassan MA, Thomsen CØ, Vilmann P
Dan Med J 2016 Apr;63(4) PMID: 27034185
Supine percutaneous nephrolithotomy, is it really effective? A systematic review of literature.
Basiri A, Mohammadi Sichani M
Urol J 2009 Spring;6(2):73-7. PMID: 19472122

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