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Gastric lymphoma

MedGen UID:
87603
•Concept ID:
C0349532
•
Neoplastic Process
Synonym: Familial primary gastric lymphoma
SNOMED CT: Gastric lymphoma (276811008); Lymphoma of stomach (276811008)
 
HPO: HP:0045038
Monarch Initiative: MONDO:0001059

Definition

Lymphoma that originates in the stomach itself. [from HPO]

Conditions with this feature

Mucosa-associated lymphoma
MedGen UID:
66942
•Concept ID:
C0242647
•
Neoplastic Process
MALT (mucosa-associated lymphoid tissue) lymphoma is a rare form of malignant non-Hodgkin lymphoma (see this term) that affects B cells and grows at the expense of lymphoid tissue associated with mucous membranes, but also occurs, more rarely, in lymph nodes.
See: Condition Record
Mucosa-associated lymphoma

Professional guidelines

PubMed

Primary gastric non-Hodgkin lymphomas: Recent advances regarding disease pathogenesis and treatment.
Diamantidis MD, Papaioannou M, Hatjiharissi E
World J Gastroenterol 2021 Sep 21;27(35):5932-5945. doi: 10.3748/wjg.v27.i35.5932. PMID: 34629810Free PMC Article
MALT lymphoma: epidemiology, clinical diagnosis and treatment.
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article
Multimodality Treatment of Gastric Lymphoma.
Ikoma N, Badgwell BD, Mansfield PF
Surg Clin North Am 2017 Apr;97(2):405-420. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.012. PMID: 28325194

Recent clinical studies

Etiology

The Effect of Surgery on the Prognosis of Gastric Lymphoma: A Meta-analysis.
Shi M, Yao Y, Ding H, Yang J, Zhang C, Wu Y, Guo T
Am Surg 2023 Dec;89(12):6147-6156. Epub 2023 Jun 13 doi: 10.1177/00031348231183126. PMID: 37309604
The clinicopathological characteristics of gastric cancer and precancerous conditions in gastric DLBCL and MALT lymphoma patients: a multi-center retrospective study.
Feng Y, Duan TJ, Huang Q, Li ZY, Liu YP, Luo MS, Lu GF, Shi W, Zhang ZY, Li HX
Ann Med 2023 Dec;55(1):2193423. doi: 10.1080/07853890.2023.2193423. PMID: 37183786Free PMC Article
MALT Lymphomas.
Cavalli F, Isaacson PG, Gascoyne RD, Zucca E
Hematology Am Soc Hematol Educ Program 2001:241-58. doi: 10.1182/asheducation-2001.1.241. PMID: 11722987
Helicobacter pylori: epidemiology and routes of transmission.
Brown LM
Epidemiol Rev 2000;22(2):283-97. doi: 10.1093/oxfordjournals.epirev.a018040. PMID: 11218379
Primary gastrointestinal lymphomas.
Cooper DL, Doria R, Salloum E
Gastroenterologist 1996 Mar;4(1):54-64. PMID: 8689146

Diagnosis

Gastric MALT lymphoma and Helicobacter pylori.
Salar A
Med Clin (Barc) 2019 Jan 18;152(2):65-71. Epub 2018 Nov 10 doi: 10.1016/j.medcli.2018.09.006. PMID: 30424932
MALT lymphoma: epidemiology, clinical diagnosis and treatment.
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article
Multimodality Treatment of Gastric Lymphoma.
Ikoma N, Badgwell BD, Mansfield PF
Surg Clin North Am 2017 Apr;97(2):405-420. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.012. PMID: 28325194
Primary gastric lymphoma.
Al-Akwaa AM, Siddiqui N, Al-Mofleh IA
World J Gastroenterol 2004 Jan;10(1):5-11. doi: 10.3748/wjg.v10.i1.5. PMID: 14695759Free PMC Article
Helicobacter pylori.
Dunn BE, Cohen H, Blaser MJ
Clin Microbiol Rev 1997 Oct;10(4):720-41. doi: 10.1128/CMR.10.4.720. PMID: 9336670Free PMC Article

Therapy

The Effect of Surgery on the Prognosis of Gastric Lymphoma: A Meta-analysis.
Shi M, Yao Y, Ding H, Yang J, Zhang C, Wu Y, Guo T
Am Surg 2023 Dec;89(12):6147-6156. Epub 2023 Jun 13 doi: 10.1177/00031348231183126. PMID: 37309604
Gastric MALT lymphoma and Helicobacter pylori.
Salar A
Med Clin (Barc) 2019 Jan 18;152(2):65-71. Epub 2018 Nov 10 doi: 10.1016/j.medcli.2018.09.006. PMID: 30424932
Multimodality Treatment of Gastric Lymphoma.
Ikoma N, Badgwell BD, Mansfield PF
Surg Clin North Am 2017 Apr;97(2):405-420. Epub 2017 Feb 14 doi: 10.1016/j.suc.2016.11.012. PMID: 28325194
MALT Lymphomas.
Cavalli F, Isaacson PG, Gascoyne RD, Zucca E
Hematology Am Soc Hematol Educ Program 2001:241-58. doi: 10.1182/asheducation-2001.1.241. PMID: 11722987
Helicobacter pylori.
Dunn BE, Cohen H, Blaser MJ
Clin Microbiol Rev 1997 Oct;10(4):720-41. doi: 10.1128/CMR.10.4.720. PMID: 9336670Free PMC Article

Prognosis

The Effect of Surgery on the Prognosis of Gastric Lymphoma: A Meta-analysis.
Shi M, Yao Y, Ding H, Yang J, Zhang C, Wu Y, Guo T
Am Surg 2023 Dec;89(12):6147-6156. Epub 2023 Jun 13 doi: 10.1177/00031348231183126. PMID: 37309604
MALT lymphoma: epidemiology, clinical diagnosis and treatment.
Violeta Filip P, Cuciureanu D, Sorina Diaconu L, Maria Vladareanu A, Silvia Pop C
J Med Life 2018 Jul-Sep;11(3):187-193. doi: 10.25122/jml-2018-0035. PMID: 30364585Free PMC Article
PET/Computed Tomography and Precision Medicine: Gastric Cancer.
Marcus C, Subramaniam RM
PET Clin 2017 Oct;12(4):437-447. Epub 2017 Jul 15 doi: 10.1016/j.cpet.2017.05.004. PMID: 28867114
MALT lymphoma: forget surgery?
Fischbach W
Dig Dis 2013;31(1):38-42. Epub 2013 Jun 17 doi: 10.1159/000347176. PMID: 23797121
Primary gastric lymphoma.
Al-Akwaa AM, Siddiqui N, Al-Mofleh IA
World J Gastroenterol 2004 Jan;10(1):5-11. doi: 10.3748/wjg.v10.i1.5. PMID: 14695759Free PMC Article

Clinical prediction guides

Primary gastric non-Hodgkin lymphomas: Recent advances regarding disease pathogenesis and treatment.
Diamantidis MD, Papaioannou M, Hatjiharissi E
World J Gastroenterol 2021 Sep 21;27(35):5932-5945. doi: 10.3748/wjg.v27.i35.5932. PMID: 34629810Free PMC Article
Gastric MALT lymphoma and Helicobacter pylori.
Salar A
Med Clin (Barc) 2019 Jan 18;152(2):65-71. Epub 2018 Nov 10 doi: 10.1016/j.medcli.2018.09.006. PMID: 30424932
PET/Computed Tomography and Precision Medicine: Gastric Cancer.
Marcus C, Subramaniam RM
PET Clin 2017 Oct;12(4):437-447. Epub 2017 Jul 15 doi: 10.1016/j.cpet.2017.05.004. PMID: 28867114
Helicobacter pylori screening: options and challenges.
Venerito M, Goni E, Malfertheiner P
Expert Rev Gastroenterol Hepatol 2016;10(4):497-503. Epub 2016 Jan 5 doi: 10.1586/17474124.2016.1126507. PMID: 26619972
MALT Lymphomas.
Cavalli F, Isaacson PG, Gascoyne RD, Zucca E
Hematology Am Soc Hematol Educ Program 2001:241-58. doi: 10.1182/asheducation-2001.1.241. PMID: 11722987

Recent systematic reviews

Radiotherapy in the management of rare gastrointestinal cancers: A systematic review.
Bellefkih FZ, Benchakroun N, Lalya I, Amaoui B, El Kacemi H, Acharki A, El Hfid M, El Mazghi A, Chekrine T, Bouchbika Z, Jouhadi H, Sahraoui S, Tawfiq N, Michalet M
Cancer Radiother 2023 Sep;27(6-7):622-637. Epub 2023 Jul 25 doi: 10.1016/j.canrad.2023.06.010. PMID: 37500390
Efficacy of Helicobater pylori eradication in patients with diffuse large B-cell lymphoma of the stomach: A systematic review.
De Francesco V, Manta R, Marmo R, Marmo C, Rago A, Antonelli G, Hassan C, Zullo A
Eur J Haematol 2022 Dec;109(6):643-647. Epub 2022 Oct 5 doi: 10.1111/ejh.13871. PMID: 36175387
A systematic review of primary gastric diffuse large B-cell lymphoma: Clinical diagnosis, staging, treatment and prognostic factors.
Bai Z, Zhou Y
Leuk Res 2021 Dec;111:106716. Epub 2021 Oct 1 doi: 10.1016/j.leukres.2021.106716. PMID: 34627052
Primary low-grade and high-grade gastric MALT-lymphoma presentation.
Zullo A, Hassan C, Andriani A, Cristofari F, Cardinale V, Spinelli GP, Tomao S, Morini S
J Clin Gastroenterol 2010 May-Jun;44(5):340-4. doi: 10.1097/MCG.0b013e3181b4b1ab. PMID: 19745757
Effects of Helicobacter pylori eradication on early stage gastric mucosa-associated lymphoid tissue lymphoma.
Zullo A, Hassan C, Cristofari F, Andriani A, De Francesco V, Ierardi E, Tomao S, Stolte M, Morini S, Vaira D
Clin Gastroenterol Hepatol 2010 Feb;8(2):105-10. Epub 2009 Jul 22 doi: 10.1016/j.cgh.2009.07.017. PMID: 19631287

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