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Posterior Urethral Valves Type 3

MedGen UID:
883089
•Concept ID:
C4054162
•
Disease or Syndrome

Definition

A posterior urethral valve, presumed to result from incomplete canalization of the urethra, that is located immediately distal to the vera montanum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPosterior Urethral Valves Type 3

Professional guidelines

PubMed

Urodynamic assessment in the management of the child's posterior urethral valves.
Hammi Y, Baati R, Ferjeni M, Sayari T, Naija O, Gargah T
Tunis Med 2021 Octobre;99(10):985-991. PMID: 35288900Free PMC Article
Angiotensin-converting enzyme and angiotensin type 2 receptor gene genotype distributions in Italian children with congenital uropathies.
Rigoli L, Chimenz R, di Bella C, Cavallaro E, Caruso R, Briuglia S, Fede C, Salpietro CD
Pediatr Res 2004 Dec;56(6):988-93. Epub 2004 Oct 6 doi: 10.1203/01.PDR.0000145252.89427.9E. PMID: 15470205

Recent clinical studies

Etiology

Surrogate imaging markers of Urodynamic proven bladder dysfunction in posterior urethral valves: A comprehensive evaluation.
Archana P, Kumar A, Rama A
J Pediatr Urol 2023 Aug;19(4):427.e1-427.e9. Epub 2023 Apr 25 doi: 10.1016/j.jpurol.2023.03.040. PMID: 37183084
Urodynamic assessment in the management of the child's posterior urethral valves.
Hammi Y, Baati R, Ferjeni M, Sayari T, Naija O, Gargah T
Tunis Med 2021 Octobre;99(10):985-991. PMID: 35288900Free PMC Article
PUVs are more common in boys with hypospadias.
Lee B, Driver CP, Flett ME, Steven L, Steven M, O'Toole S
J Pediatr Urol 2020 Jun;16(3):299-303. Epub 2020 Mar 8 doi: 10.1016/j.jpurol.2020.02.014. PMID: 32234419
Presentation, management, and outcome of posterior urethral valves in a Nigerian tertiary hospital.
Orumuah AJ, Oduagbon OE
Afr J Paediatr Surg 2015 Jan-Mar;12(1):18-22. doi: 10.4103/0189-6725.150937. PMID: 25659544Free PMC Article
Ultrasound diagnosis of fetal renal abnormalities.
Dias T, Sairam S, Kumarasiri S
Best Pract Res Clin Obstet Gynaecol 2014 Apr;28(3):403-15. Epub 2014 Jan 29 doi: 10.1016/j.bpobgyn.2014.01.009. PMID: 24524801

Diagnosis

Surrogate imaging markers of Urodynamic proven bladder dysfunction in posterior urethral valves: A comprehensive evaluation.
Archana P, Kumar A, Rama A
J Pediatr Urol 2023 Aug;19(4):427.e1-427.e9. Epub 2023 Apr 25 doi: 10.1016/j.jpurol.2023.03.040. PMID: 37183084
Urodynamic assessment in the management of the child's posterior urethral valves.
Hammi Y, Baati R, Ferjeni M, Sayari T, Naija O, Gargah T
Tunis Med 2021 Octobre;99(10):985-991. PMID: 35288900Free PMC Article
PUVs are more common in boys with hypospadias.
Lee B, Driver CP, Flett ME, Steven L, Steven M, O'Toole S
J Pediatr Urol 2020 Jun;16(3):299-303. Epub 2020 Mar 8 doi: 10.1016/j.jpurol.2020.02.014. PMID: 32234419
Presentation, management, and outcome of posterior urethral valves in a Nigerian tertiary hospital.
Orumuah AJ, Oduagbon OE
Afr J Paediatr Surg 2015 Jan-Mar;12(1):18-22. doi: 10.4103/0189-6725.150937. PMID: 25659544Free PMC Article
Ultrasound diagnosis of fetal renal abnormalities.
Dias T, Sairam S, Kumarasiri S
Best Pract Res Clin Obstet Gynaecol 2014 Apr;28(3):403-15. Epub 2014 Jan 29 doi: 10.1016/j.bpobgyn.2014.01.009. PMID: 24524801

Therapy

Long-term Outcome of Renal Transplantation in Patients with Congenital Lower Urinary Tract Malformations: A Multicenter Study.
Marchal S, Kalfa N, Iborra F, Badet L, Karam G, Broudeur L, Branchereau J, Abdo N, Thuret R
Transplantation 2020 Jan;104(1):165-171. doi: 10.1097/TP.0000000000002746. PMID: 30964838
Surgical Challenge in Pediatric Kidney Transplant: Lower Urinary Tract Abnormality.
Aikawa A, Muramatsu M, Takahashi Y, Hamasaki Y, Hashimoto J, Kubota M, Hyoudou Y, Itabashi Y, Kawamura T, Shishido S
Exp Clin Transplant 2018 Mar;16 Suppl 1(Suppl 1):20-24. doi: 10.6002/ect.TOND-TDTD2017.L42. PMID: 29527985
Urological complications and vesicoureteral reflux following pediatric kidney transplantation.
Routh JC, Yu RN, Kozinn SI, Nguyen HT, Borer JG
J Urol 2013 Mar;189(3):1071-6. Epub 2012 Sep 25 doi: 10.1016/j.juro.2012.09.091. PMID: 23022008
Cutaneous vesicostomy revisited--the second 15 years.
Vastyan AM, Pinter AB, Farkas A, Vajda P, Somogyi R, Juhasz Z
Eur J Pediatr Surg 2005 Jun;15(3):170-4. doi: 10.1055/s-2005-837609. PMID: 15999309
Continent urinary diversion: 10-year experience of Shriners Hospitals for Children in Chicago.
Chulamorkodt NN, Estrada CR, Chaviano AH
J Spinal Cord Med 2004;27 Suppl 1:S84-7. doi: 10.1080/10790268.2004.11753447. PMID: 15503708

Prognosis

Surrogate imaging markers of Urodynamic proven bladder dysfunction in posterior urethral valves: A comprehensive evaluation.
Archana P, Kumar A, Rama A
J Pediatr Urol 2023 Aug;19(4):427.e1-427.e9. Epub 2023 Apr 25 doi: 10.1016/j.jpurol.2023.03.040. PMID: 37183084
Are pressure pop-offs beneficial to the bladder in boys with posterior urethral valves?
D'Oro A, Meyer T, Gong EM, Rosoklija I, Liu DB
J Pediatr Urol 2020 Aug;16(4):488.e1-488.e8. Epub 2020 Jun 3 doi: 10.1016/j.jpurol.2020.05.154. PMID: 32605875
Posterior urethral valves: 10 years audit of epidemiologic, diagnostic and therapeutic aspects in Yaoundé gynaeco-obstetric and paediatric hospital.
Tambo FFM, Tolefac PN, Ngowe MN, Minkande JZ, Mbouche L, Guemkam G, Telelen NA, Angwafo FF 3rd, Sosso AM
BMC Urol 2018 May 21;18(1):46. doi: 10.1186/s12894-018-0364-1. PMID: 29783971Free PMC Article
Presentation, management, and outcome of posterior urethral valves in a Nigerian tertiary hospital.
Orumuah AJ, Oduagbon OE
Afr J Paediatr Surg 2015 Jan-Mar;12(1):18-22. doi: 10.4103/0189-6725.150937. PMID: 25659544Free PMC Article
Protective factors in posterior urethral valves.
Rittenberg MH, Hulbert WC, Snyder HM 3rd, Duckett JW
J Urol 1988 Nov;140(5):993-6. doi: 10.1016/s0022-5347(17)41908-2. PMID: 3139895

Clinical prediction guides

Surrogate imaging markers of Urodynamic proven bladder dysfunction in posterior urethral valves: A comprehensive evaluation.
Archana P, Kumar A, Rama A
J Pediatr Urol 2023 Aug;19(4):427.e1-427.e9. Epub 2023 Apr 25 doi: 10.1016/j.jpurol.2023.03.040. PMID: 37183084
The Endoscopic Morphological Features of Congenital Posterior Urethral Obstructions in Boys with Refractory Daytime Urinary Incontinence and Nocturnal Enuresis.
Nakamura S, Hyuga T, Kawai S, Kubo T, Nakai H
Eur J Pediatr Surg 2016 Aug;26(4):368-75. Epub 2015 Sep 17 doi: 10.1055/s-0035-1563401. PMID: 26378483
Expression of parathyroid hormone/parathyroid hormone-related peptide receptor 1 in normal and diseased bladder detrusor muscles: a clinico-pathological study.
Nishikawa N, Yago R, Yamazaki Y, Negoro H, Suzuki M, Imamura M, Toda Y, Tanabe K, Ogawa O, Kanematsu A
BMC Urol 2015 Jan 21;15(1):2. doi: 10.1186/1471-2490-15-2. PMID: 25604159Free PMC Article
Influence of initial therapy on progression of renal failure and body growth in children with posterior urethral valves.
Reinberg Y, de Castano I, Gonzalez R
J Urol 1992 Aug;148(2 Pt 2):532-3. doi: 10.1016/s0022-5347(17)36645-4. PMID: 1640516
Prognostic features in infants with obstructive uropathy due to posterior urethral valves.
Warshaw BL, Hymes LC, Trulock TS, Woodard JR
J Urol 1985 Feb;133(2):240-3. doi: 10.1016/s0022-5347(17)48899-9. PMID: 3968741

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