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Lepidic Adenocarcinoma

MedGen UID:
883345
Concept ID:
C4049711
Neoplastic Process
Synonyms: Lepidic Predominant Adenocarcinoma; Lepidic Predominant Lung Adenocarcinoma

Definition

A lung adenocarcinoma characterized by the presence of mildly and moderately differentiated adenocarcinoma cells across the alveolar walls with at least one focus of invasive carcinoma measuring more than 5 mm in greatest dimension. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVLepidic Adenocarcinoma

Professional guidelines

PubMed

Zhao R, Li J, Guo L, Xiang C, Chen S, Zhao J, Shao J, Zhu L, Ye M, Qin G, Chu T, Han Y
Target Oncol 2024 Mar;19(2):277-288. Epub 2024 Feb 28 doi: 10.1007/s11523-024-01042-3. PMID: 38416376
Visca P, Gallo E, Marino M
J Thorac Oncol 2023 Apr;18(4):387-389. doi: 10.1016/j.jtho.2023.01.001. PMID: 36990568
Yambayev I, Sullivan TB, Suzuki K, Zhao Q, Higgins SE, Yilmaz OH, Litle VR, Moreira P, Servais EL, Stock CT, Quadri SM, Williamson C, Rieger-Christ KM, Burks EJ
Am J Surg Pathol 2021 Apr 1;45(4):567-576. doi: 10.1097/PAS.0000000000001618. PMID: 33177339

Recent clinical studies

Etiology

Ng JKM, Cheung W, Li JJX, Chan KP, Yip WH, Tse GM
Ann Diagn Pathol 2023 Dec;67:152191. Epub 2023 Aug 10 doi: 10.1016/j.anndiagpath.2023.152191. PMID: 37579536
Santos IR, Raiter J, Lamego ÉC, Bandinelli MB, Dal Pont TP, Siqueira KF, Almeida BA, Panzeira W, Sonne L, Driemeier D, Pavarini SP
Vet Pathol 2023 Jan;60(1):8-20. Epub 2022 Sep 13 doi: 10.1177/03009858221122517. PMID: 36112908
Starnes SL
Semin Thorac Cardiovasc Surg 2023 Summer;35(2):410-411. Epub 2022 Apr 2 doi: 10.1053/j.semtcvs.2022.03.007. PMID: 35381353
Tang H, Qiao C, Wang Y, Bai C
Can Respir J 2022;2022:3676547. Epub 2022 Aug 31 doi: 10.1155/2022/3676547. PMID: 36091329Free PMC Article
Mase VJ Jr, Detterbeck FC
Clin Chest Med 2020 Mar;41(1):99-113. doi: 10.1016/j.ccm.2019.11.004. PMID: 32008632

Diagnosis

Ng JKM, Cheung W, Li JJX, Chan KP, Yip WH, Tse GM
Ann Diagn Pathol 2023 Dec;67:152191. Epub 2023 Aug 10 doi: 10.1016/j.anndiagpath.2023.152191. PMID: 37579536
Elsolh B, Bayat Z, Lyu D, Lin J, Wakeam E
J Heart Lung Transplant 2023 Oct;42(10):1425-1436. Epub 2023 May 28 doi: 10.1016/j.healun.2023.05.011. PMID: 37253398
Santos IR, Raiter J, Lamego ÉC, Bandinelli MB, Dal Pont TP, Siqueira KF, Almeida BA, Panzeira W, Sonne L, Driemeier D, Pavarini SP
Vet Pathol 2023 Jan;60(1):8-20. Epub 2022 Sep 13 doi: 10.1177/03009858221122517. PMID: 36112908
Tang H, Qiao C, Wang Y, Bai C
Can Respir J 2022;2022:3676547. Epub 2022 Aug 31 doi: 10.1155/2022/3676547. PMID: 36091329Free PMC Article
Mase VJ Jr, Detterbeck FC
Clin Chest Med 2020 Mar;41(1):99-113. doi: 10.1016/j.ccm.2019.11.004. PMID: 32008632

Therapy

Elsolh B, Bayat Z, Lyu D, Lin J, Wakeam E
J Heart Lung Transplant 2023 Oct;42(10):1425-1436. Epub 2023 May 28 doi: 10.1016/j.healun.2023.05.011. PMID: 37253398
Maurizi G, D'Andrilli A, Argento G, Ciccone AM, Ibrahim M, Andreetti C, Vanni C, Tierno SM, Venuta F, Rendina EA
Semin Thorac Cardiovasc Surg 2023 Summer;35(2):399-409. Epub 2022 Mar 8 doi: 10.1053/j.semtcvs.2021.11.020. PMID: 35272026
Kunal S, Jain S, Shah A
Monaldi Arch Chest Dis 2017 Dec 19;87(3):864. doi: 10.4081/monaldi.2017.864. PMID: 29424200
Gao RW, Berry MF, Kunder CA, Khuong AA, Wakelee H, Neal JW, Backhus LM, Shrager JB
J Thorac Cardiovasc Surg 2017 Dec;154(6):2092-2099.e2. Epub 2017 Aug 1 doi: 10.1016/j.jtcvs.2017.07.034. PMID: 28863952
Cadranel J, Gervais R, Merle P, Moro-Sibilot D, Westeel V, Bigay-Game L, Quoix E, Friard S, Barlesi F, Lethrosne C, Moreau L, Monnet I, Salaun M, Oliviero G, Souquet PJ, Antoine M, Langlais A, Morin F, Wislez M, Zalcman G; Intergroupe Francophone de Cancérologie Thoracique (IFCT)
Eur Respir J 2015 Nov;46(5):1440-50. Epub 2015 Sep 17 doi: 10.1183/13993003.02358-2014. PMID: 26381515

Prognosis

Maurizi G, D'Andrilli A, Argento G, Ciccone AM, Ibrahim M, Andreetti C, Vanni C, Tierno SM, Venuta F, Rendina EA
Semin Thorac Cardiovasc Surg 2023 Summer;35(2):399-409. Epub 2022 Mar 8 doi: 10.1053/j.semtcvs.2021.11.020. PMID: 35272026
Tang H, Qiao C, Wang Y, Bai C
Can Respir J 2022;2022:3676547. Epub 2022 Aug 31 doi: 10.1155/2022/3676547. PMID: 36091329Free PMC Article
Akhtar Z, Laageide L, Robles J, Winters C, Wall GC, Mallen J, Jawa Z
BMC Pulm Med 2022 May 16;22(1):197. doi: 10.1186/s12890-022-01969-1. PMID: 35578218Free PMC Article
Shao X, Niu R, Jiang Z, Shao X, Wang Y
AJR Am J Roentgenol 2020 Feb;214(2):437-445. Epub 2019 Nov 12 doi: 10.2214/AJR.19.21585. PMID: 31714848
Cox ML, Yang CJ, Speicher PJ, Anderson KL, Fitch ZW, Gu L, Davis RP, Wang X, D'Amico TA, Hartwig MG, Harpole DH Jr, Berry MF
J Thorac Oncol 2017 Apr;12(4):689-696. Epub 2017 Jan 8 doi: 10.1016/j.jtho.2017.01.003. PMID: 28082103Free PMC Article

Clinical prediction guides

Santos IR, Raiter J, Lamego ÉC, Bandinelli MB, Dal Pont TP, Siqueira KF, Almeida BA, Panzeira W, Sonne L, Driemeier D, Pavarini SP
Vet Pathol 2023 Jan;60(1):8-20. Epub 2022 Sep 13 doi: 10.1177/03009858221122517. PMID: 36112908
Tang H, Qiao C, Wang Y, Bai C
Can Respir J 2022;2022:3676547. Epub 2022 Aug 31 doi: 10.1155/2022/3676547. PMID: 36091329Free PMC Article
Shao X, Niu R, Jiang Z, Shao X, Wang Y
AJR Am J Roentgenol 2020 Feb;214(2):437-445. Epub 2019 Nov 12 doi: 10.2214/AJR.19.21585. PMID: 31714848
Suzuki S, Sakurai H, Masai K, Asakura K, Nakagawa K, Motoi N, Watanabe SI
Ann Thorac Surg 2017 Sep;104(3):1027-1032. Epub 2017 May 24 doi: 10.1016/j.athoracsur.2017.02.067. PMID: 28551046
Cox ML, Yang CJ, Speicher PJ, Anderson KL, Fitch ZW, Gu L, Davis RP, Wang X, D'Amico TA, Hartwig MG, Harpole DH Jr, Berry MF
J Thorac Oncol 2017 Apr;12(4):689-696. Epub 2017 Jan 8 doi: 10.1016/j.jtho.2017.01.003. PMID: 28082103Free PMC Article

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