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Bovine Leukoses, Enzootic

MedGen UID:
88344
•Concept ID:
C0085165
•
Neoplastic Process
Synonyms: Bovine Leukoses; Bovine Leukosis; Bovine Leukosis, Enzootic; Enzootic Bovine Leukoses; Enzootic Bovine Leukosis; Leukoses, Bovine; Leukoses, Enzootic Bovine; Leukosis, Bovine; Leukosis, Enzootic Bovine

Definition

A lymphoid neoplastic disease in cattle caused by the bovine leukemia virus. Enzootic bovine leukosis may take the form of lymphosarcoma, malignant lymphoma, or leukemia but the presence of malignant cells in the blood is not a consistent finding. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBovine Leukoses, Enzootic

Recent clinical studies

Etiology

Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells.
Okagawa T, Shimakura H, Konnai S, Saito M, Matsudaira T, Nao N, Yamada S, Murakami K, Maekawa N, Murata S, Ohashi K
Microbiol Spectr 2022 Dec 21;10(6):e0259522. Epub 2022 Oct 13 doi: 10.1128/spectrum.02595-22. PMID: 36227090Free PMC Article
Co-Circulation of Bovine Leukemia Virus Haplotypes among Humans, Animals, and Food Products: New Insights of Its Zoonotic Potential.
Corredor-Figueroa AP, Olaya-Galán NN, Velandia-Álvarez S, Muñoz M, Salas-Cárdenas SP, Ibáñez-Pinilla M, Patarroyo MA, Gutiérrez MF
Int J Environ Res Public Health 2021 May 4;18(9) doi: 10.3390/ijerph18094883. PMID: 34064361Free PMC Article
Epigenetics evaluation of the oncogenic mechanisms of two closely related bovine and human deltaretroviruses: A system biology study.
Ashrafi F, Nassiri M, Javadmanesh A, Rahimi H, Rezaee SA
Microb Pathog 2020 Feb;139:103845. Epub 2019 Nov 4 doi: 10.1016/j.micpath.2019.103845. PMID: 31698053
Molecular characterization of bovine leukemia virus from Moldovan dairy cattle.
Pluta A, Rola-Łuszczak M, Kubiś P, Balov S, Moskalik R, Choudhury B, Kuźmak J
Arch Virol 2017 Jun;162(6):1563-1576. Epub 2017 Feb 17 doi: 10.1007/s00705-017-3241-4. PMID: 28213870Free PMC Article
Should we be more concerned about bovine leukemia virus?
Gyles C
Can Vet J 2016 Feb;57(2):115-6. PMID: 26834261Free PMC Article

Diagnosis

Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells.
Okagawa T, Shimakura H, Konnai S, Saito M, Matsudaira T, Nao N, Yamada S, Murakami K, Maekawa N, Murata S, Ohashi K
Microbiol Spectr 2022 Dec 21;10(6):e0259522. Epub 2022 Oct 13 doi: 10.1128/spectrum.02595-22. PMID: 36227090Free PMC Article
Characterization of miRNAs in Milk Small Extracellular Vesicles from Enzootic Bovine Leukosis Cattle.
Tsukada F, Takashima S, Wakihara Y, Kamatari YO, Shimizu K, Okada A, Inoshima Y
Int J Mol Sci 2022 Sep 15;23(18) doi: 10.3390/ijms231810782. PMID: 36142686Free PMC Article
Bovine leukemia virus linked to breast cancer but not coinfection with human papillomavirus: Case-control study of women in Texas.
Baltzell KA, Shen HM, Krishnamurthy S, Sison JD, Nuovo GJ, Buehring GC
Cancer 2018 Apr 1;124(7):1342-1349. Epub 2017 Dec 20 doi: 10.1002/cncr.31169. PMID: 29266207
Bovine leukaemia virus DNA in fresh milk and raw beef for human consumption.
Olaya-Galán NN, Corredor-Figueroa AP, Guzmán-Garzón TC, Ríos-Hernandez KS, Salas-Cárdenas SP, Patarroyo MA, Gutierrez MF
Epidemiol Infect 2017 Nov;145(15):3125-3130. Epub 2017 Sep 28 doi: 10.1017/S0950268817002229. PMID: 28956522Free PMC Article
No genetic evidence for involvement of Deltaretroviruses in adult patients with precursor and mature T-cell neoplasms.
Burmeister T, Schwartz S, Hummel M, Hoelzer D, Thiel E
Retrovirology 2007 Feb 7;4:11. doi: 10.1186/1742-4690-4-11. PMID: 17284327Free PMC Article

Therapy

Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells.
Okagawa T, Shimakura H, Konnai S, Saito M, Matsudaira T, Nao N, Yamada S, Murakami K, Maekawa N, Murata S, Ohashi K
Microbiol Spectr 2022 Dec 21;10(6):e0259522. Epub 2022 Oct 13 doi: 10.1128/spectrum.02595-22. PMID: 36227090Free PMC Article
Mechanisms of leukemogenesis induced by bovine leukemia virus: prospects for novel anti-retroviral therapies in human.
Gillet N, Florins A, Boxus M, Burteau C, Nigro A, Vandermeers F, Balon H, Bouzar AB, Defoiche J, Burny A, Reichert M, Kettmann R, Willems L
Retrovirology 2007 Mar 16;4:18. doi: 10.1186/1742-4690-4-18. PMID: 17362524Free PMC Article
Protection of cattle against bovine leukemia virus (BLV) infection could be attained by DNA vaccination.
Brillowska A, Dabrowski S, Rułka J, Kubiś P, Buzała E, Kur J
Acta Biochim Pol 1999;46(4):971-6. PMID: 10824867
Comparative approach to retroviral vaccines.
Burny A
AIDS Res Hum Retroviruses 1996 Mar 20;12(5):389-92. doi: 10.1089/aid.1996.12.389. PMID: 8882316

Prognosis

Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells.
Okagawa T, Shimakura H, Konnai S, Saito M, Matsudaira T, Nao N, Yamada S, Murakami K, Maekawa N, Murata S, Ohashi K
Microbiol Spectr 2022 Dec 21;10(6):e0259522. Epub 2022 Oct 13 doi: 10.1128/spectrum.02595-22. PMID: 36227090Free PMC Article
Characterization of miRNAs in Milk Small Extracellular Vesicles from Enzootic Bovine Leukosis Cattle.
Tsukada F, Takashima S, Wakihara Y, Kamatari YO, Shimizu K, Okada A, Inoshima Y
Int J Mol Sci 2022 Sep 15;23(18) doi: 10.3390/ijms231810782. PMID: 36142686Free PMC Article
Molecular insight into the study of adult T-cell leukemia/lymphoma (ATLL): Ten-year studies on HTLV-1 associated diseases in an endemic region.
Ashrafi F, Rahimzada M, Parandi M, Mirhosseini A, Mashkani B, Ahmadi Ghezeldasht S, Soltani A, Rafatpanah H, Mosavat A, Abdolrahim Rezaee S
Gene 2022 Dec 30;847:146885. Epub 2022 Sep 13 doi: 10.1016/j.gene.2022.146885. PMID: 36108787
High positivity values for bovine leukemia virus in human breast cancer cases from Minas Gerais, Brazil.
Delarmelina E, Buzelin MA, Souza BS, Souto FM, Bicalho JM, Câmara RJF, Resende CF, Bueno BL, Victor RM, Galinari GCF, Nunes CB, Leite RC, Costa ÉA, Reis JKPD
PLoS One 2020;15(10):e0239745. Epub 2020 Oct 5 doi: 10.1371/journal.pone.0239745. PMID: 33017448Free PMC Article
Bovine leukemia virus linked to breast cancer but not coinfection with human papillomavirus: Case-control study of women in Texas.
Baltzell KA, Shen HM, Krishnamurthy S, Sison JD, Nuovo GJ, Buehring GC
Cancer 2018 Apr 1;124(7):1342-1349. Epub 2017 Dec 20 doi: 10.1002/cncr.31169. PMID: 29266207

Clinical prediction guides

Diagnosis and Early Prediction of Lymphoma Using High-Throughput Clonality Analysis of Bovine Leukemia Virus-Infected Cells.
Okagawa T, Shimakura H, Konnai S, Saito M, Matsudaira T, Nao N, Yamada S, Murakami K, Maekawa N, Murata S, Ohashi K
Microbiol Spectr 2022 Dec 21;10(6):e0259522. Epub 2022 Oct 13 doi: 10.1128/spectrum.02595-22. PMID: 36227090Free PMC Article
Characterization of miRNAs in Milk Small Extracellular Vesicles from Enzootic Bovine Leukosis Cattle.
Tsukada F, Takashima S, Wakihara Y, Kamatari YO, Shimizu K, Okada A, Inoshima Y
Int J Mol Sci 2022 Sep 15;23(18) doi: 10.3390/ijms231810782. PMID: 36142686Free PMC Article
Bovine Leukemia Virus and Mycobacterium avium subsp. paratuberculosis Are Not Associated with Shiga Toxin-Producing Escherichia coli Shedding in Cattle.
Venegas-Vargas C, Manning SD, Coussens PM, Roussey JA, Bartlett P, Grooms D
J Food Prot 2017 Jan;80(1):86-89. doi: 10.4315/0362-028X.JFP-16-090. PMID: 28221870
Molecular characterization of bovine leukemia virus from Moldovan dairy cattle.
Pluta A, Rola-Łuszczak M, Kubiś P, Balov S, Moskalik R, Choudhury B, Kuźmak J
Arch Virol 2017 Jun;162(6):1563-1576. Epub 2017 Feb 17 doi: 10.1007/s00705-017-3241-4. PMID: 28213870Free PMC Article
Distribution of bovine leukemia virus proviral sequences in tissues of bovine, ovine and human origin.
Kettmann R, Burny A, Cleuter Y, Ghysdael J, Mammerickx M
Ann Rech Vet 1978;9(4):837-44. PMID: 224785

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