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Bone Tumor of Undefined Neoplastic Nature

MedGen UID:
886135
•Concept ID:
C4055372
•
Disease or Syndrome

Definition

A group of lesions that affect the bone and have the appearance and cytogenetic or molecular characteristics of neoplasms but the clinical behavior is suggestive of a non-neoplastic process. [from NCI]

Recent clinical studies

Etiology

Diagnostic accuracies of intraoperative frozen section and permanent section examinations for histological grades during open biopsy of bone tumors.
Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tada K, Higuchi T, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H, Nojima T, Tsuchiya H
Int J Clin Oncol 2021 Mar;26(3):613-619. Epub 2020 Nov 23 doi: 10.1007/s10147-020-01836-1. PMID: 33225397
The histiocytoid hemangiomas. A unifying concept embracing several previously described entities of skin, soft tissue, large vessels, bone, and heart.
Rosai J, Gold J, Landy R
Hum Pathol 1979 Nov;10(6):707-30. doi: 10.1016/s0046-8177(79)80114-8. PMID: 527967

Diagnosis

Diagnostic accuracies of intraoperative frozen section and permanent section examinations for histological grades during open biopsy of bone tumors.
Miwa S, Yamamoto N, Hayashi K, Takeuchi A, Igarashi K, Tada K, Higuchi T, Yonezawa H, Morinaga S, Araki Y, Asano Y, Ikeda H, Nojima T, Tsuchiya H
Int J Clin Oncol 2021 Mar;26(3):613-619. Epub 2020 Nov 23 doi: 10.1007/s10147-020-01836-1. PMID: 33225397
Fine-Needle Aspiration Cytology in Preoperative Diagnosis of Bone Lesions: A Three-Year Study in a Tertiary Care Hospital.
Vangala N, Uppin SG, Pamu PK, Hui M, Nageshwara Rao K, Chandrashekar P
Acta Cytol 2021;65(1):75-87. Epub 2020 Nov 12 doi: 10.1159/000511259. PMID: 33181515

Therapy

Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells.
Liang W, Li X, Li Y, Li C, Gao B, Gan H, Li S, Shen J, Kang J, Ding S, Lin X, Liao L
Int J Oncol 2014 Jan;44(1):91-8. Epub 2013 Oct 30 doi: 10.3892/ijo.2013.2155. PMID: 24173143

Clinical prediction guides

Gallic acid induces apoptosis and inhibits cell migration by upregulating miR-518b in SW1353 human chondrosarcoma cells.
Liang W, Li X, Li Y, Li C, Gao B, Gan H, Li S, Shen J, Kang J, Ding S, Lin X, Liao L
Int J Oncol 2014 Jan;44(1):91-8. Epub 2013 Oct 30 doi: 10.3892/ijo.2013.2155. PMID: 24173143
Parathyroid hormone-related protein inhibits DKK1 expression through c-Jun-mediated inhibition of β-catenin activation of the DKK1 promoter in prostate cancer.
Zhang H, Yu C, Dai J, Keller JM, Hua A, Sottnik JL, Shelley G, Hall CL, Park SI, Yao Z, Zhang J, McCauley LK, Keller ET
Oncogene 2014 May 8;33(19):2464-77. Epub 2013 Jun 10 doi: 10.1038/onc.2013.203. PMID: 23752183Free PMC Article

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