U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Pseudopelade of Brocq

MedGen UID:
88640
•Concept ID:
C0086873
•
Disease or Syndrome
Synonyms: Brocq pseudopelade; Pseudo-pelade of Brocq
SNOMED CT: Pseudopelade of Brocq (238731001); Alopecia cicatrisata (400088006); Pseudopelade (238731001)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
•Concept ID:
CN307044
•
Finding
Source: Orphanet
clinical entity without genetic inheritance.
See: This record
Not genetically inherited (Orphanet)
 
Monarch Initiative: MONDO:0015261
Orphanet: ORPHA129

Definition

Pseudo-pelade of Brocq is a rare hair abnormality characterized by onset in adulthood of soft, irregular, flesh-toned patches of alopecia primarily in the parietal and vertex portions of the scalp, without follicular hyperkeratosis or perifollicular inflammation. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPseudopelade of Brocq
Follow this link to review classifications for Pseudopelade of Brocq in Orphanet.

Professional guidelines

PubMed

Diagnosis and management of primary cicatricial alopecia: part I.
Otberg N, Wu WY, McElwee KJ, Shapiro J
Skinmed 2008 Jan-Feb;7(1):19-26. doi: 10.1111/j.1540-9740.2007.07163.x. PMID: 18174797
Value of direct immunofluorescence for differential diagnosis of cicatricial alopecia.
Trachsler S, Trueb RM
Dermatology 2005;211(2):98-102. doi: 10.1159/000086436. PMID: 16088153

Recent clinical studies

Etiology

Have Skin Biopsy Results in Adults Been Affected in the COVID-19 Pandemic?
Çölgeçen E, Gökçek GE, Şahin S
Acta Dermatovenerol Croat 2022 Jul;30(1):40-48. PMID: 36153718
Primary scarring alopecia: A retrospective study of 89 patients in Taiwan.
Su HJ, Cheng AY, Liu CH, Chu CB, Lee CN, Hsu CK, Lee JY, Yang CC
J Dermatol 2018 Apr;45(4):450-455. Epub 2018 Jan 16 doi: 10.1111/1346-8138.14217. PMID: 29341216
Clinical features of primary cicatricial alopecia in Chinese patients.
Qi S, Zhao Y, Zhang X, Li S, Cao H, Zhang X
Indian J Dermatol Venereol Leprol 2014 Jul-Aug;80(4):306-12. doi: 10.4103/0378-6323.136833. PMID: 25035354
Alopecia areata mimicking pseudopelade of Brocq.
Kittridge A, Haught JM, English JC 3rd
Cutis 2010 Oct;86(4):187-9. PMID: 21140926
Value of direct immunofluorescence for differential diagnosis of cicatricial alopecia.
Trachsler S, Trueb RM
Dermatology 2005;211(2):98-102. doi: 10.1159/000086436. PMID: 16088153

Diagnosis

Histopathology of alopecia: a clinicopathological approach to diagnosis.
Stefanato CM
Histopathology 2010 Jan;56(1):24-38. doi: 10.1111/j.1365-2559.2009.03439.x. PMID: 20055903
Lichen planopilaris and pseudopelade of Brocq involve distinct disease associated gene expression patterns by microarray.
Yu M, Bell RH, Ross EK, Lo BK, Isaac-Renton M, Martinka M, Haegert A, Shapiro J, McElwee KJ
J Dermatol Sci 2010 Jan;57(1):27-36. Epub 2009 Nov 22 doi: 10.1016/j.jdermsci.2009.10.011. PMID: 19932600
Pseudopelade of Brocq.
Alzolibani AA, Kang H, Otberg N, Shapiro J
Dermatol Ther 2008 Jul-Aug;21(4):257-63. doi: 10.1111/j.1529-8019.2008.00207.x. PMID: 18715295
Diagnosis and management of primary cicatricial alopecia: part I.
Otberg N, Wu WY, McElwee KJ, Shapiro J
Skinmed 2008 Jan-Feb;7(1):19-26. doi: 10.1111/j.1540-9740.2007.07163.x. PMID: 18174797
Pseudopelade of Brocq.
Braun-Falco O, Imai S, Schmoeckel C, Steger O, Bergner T
Dermatologica 1986;172(1):18-23. doi: 10.1159/000249287. PMID: 3956816

Therapy

Alopecia areata mimicking pseudopelade of Brocq.
Kittridge A, Haught JM, English JC 3rd
Cutis 2010 Oct;86(4):187-9. PMID: 21140926
Pseudopelade of Brocq in a child.
Bulengo-Ransby SM, Headington JT
J Am Acad Dermatol 1990 Nov;23(5 Pt 1):944-5. doi: 10.1016/s0190-9622(08)80706-2. PMID: 2135949

Prognosis

Clinical features of primary cicatricial alopecia in Chinese patients.
Qi S, Zhao Y, Zhang X, Li S, Cao H, Zhang X
Indian J Dermatol Venereol Leprol 2014 Jul-Aug;80(4):306-12. doi: 10.4103/0378-6323.136833. PMID: 25035354
Alopecia areata mimicking pseudopelade of Brocq.
Kittridge A, Haught JM, English JC 3rd
Cutis 2010 Oct;86(4):187-9. PMID: 21140926
Pseudopelade of Brocq.
Alzolibani AA, Kang H, Otberg N, Shapiro J
Dermatol Ther 2008 Jul-Aug;21(4):257-63. doi: 10.1111/j.1529-8019.2008.00207.x. PMID: 18715295
Pseudopelade of Brocq.
Braun-Falco O, Imai S, Schmoeckel C, Steger O, Bergner T
Dermatologica 1986;172(1):18-23. doi: 10.1159/000249287. PMID: 3956816

Clinical prediction guides

Have Skin Biopsy Results in Adults Been Affected in the COVID-19 Pandemic?
Çölgeçen E, Gökçek GE, Şahin S
Acta Dermatovenerol Croat 2022 Jul;30(1):40-48. PMID: 36153718
Evaluation of inflammatory infiltrate and fibrogenic cytokines in pseudopelade of Brocq suggests the involvement of T-helper 2 and 3 cytokines.
Moretti S, Amato L, Massi D, Bianchi B, Gallerani I, Fabbri P
Br J Dermatol 2004 Jul;151(1):84-90. doi: 10.1111/j.1365-2133.2004.05976.x. PMID: 15270875

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Reviews

    Related information

    • MeSH
      Related Medical Subject Headings
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...