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Pneumatosis Intestinalis

MedGen UID:
886640
•Concept ID:
C1112565
•
Disease or Syndrome

Definition

The presence of gas within the wall of the large or small intestine. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVPneumatosis Intestinalis

Professional guidelines

PubMed

Gastrointestinal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.
Typpo KV, Irving SY, Prince JM, Pathan N, Brown AM; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative
Pediatrics 2022 Jan 1;149(1 Suppl 1):S53-S58. doi: 10.1542/peds.2021-052888H. PMID: 34970680Free PMC Article
Pneumatosis intestinalis during treatment for bullous pemphigoid.
Iinuma S, Takahashi C, Oba M, Ishida-Yamamoto A
Int J Dermatol 2022 Apr;61(4):e131-e132. Epub 2021 Jun 20 doi: 10.1111/ijd.15713. PMID: 34151430
Conservative Management of Pneumatosis Intestinalis and Portal Venous Gas After Pediatric Liver Transplantation.
Ryan JL, Dandridge LM, Andrews WS, Daniel JF, Fischer RT, Rivard DC, Wieser AB, Kane BJ, Hendrickson RJ
Transplant Proc 2020 Apr;52(3):938-942. Epub 2020 Feb 29 doi: 10.1016/j.transproceed.2020.01.010. PMID: 32122661

Recent clinical studies

Etiology

An Update on Acute Mesenteric Ischemia.
Yu H, Kirkpatrick IDC
Can Assoc Radiol J 2023 Feb;74(1):160-171. Epub 2022 May 11 doi: 10.1177/08465371221094280. PMID: 35544414
Pneumatosis Intestinalis and Anorexia Nervosa.
Gibson D, Watters A, Pieracci F, Reiss R, Mehler PS
Surg Infect (Larchmt) 2022 Sep;23(7):661-666. Epub 2022 Aug 16 doi: 10.1089/sur.2022.127. PMID: 35969259
GASTROINTESTINAL COMPLICATIONS OF CORONAVIRUS DISEASE (COVID-19).
Ribeiro-Junior MAF, Augusto SS, Elias YGB, Costa CTK, Néder PR
Arq Bras Cir Dig 2022;34(3):e1620. Epub 2022 Jan 5 doi: 10.1590/0102-672020210002e1620. PMID: 35019132Free PMC Article
Pneumatosis intestinalis in the pediatric oncology population: An 11-year retrospective review at Memorial Sloan Kettering Cancer Center.
Bailey KA, Kodikara H, Mauguen A, Price A, LaQuaglia M, Boulad F
Pediatr Blood Cancer 2022 Jul;69(7):e29539. Epub 2021 Dec 28 doi: 10.1002/pbc.29539. PMID: 34962703Free PMC Article
Necrotizing enterocolitis.
Frantz ID 3rd, L'heureux P, Engel RR, Hunt CE
J Pediatr 1975 Feb;86(2):259-63. doi: 10.1016/s0022-3476(75)80485-9. PMID: 803385

Diagnosis

An Update on Acute Mesenteric Ischemia.
Yu H, Kirkpatrick IDC
Can Assoc Radiol J 2023 Feb;74(1):160-171. Epub 2022 May 11 doi: 10.1177/08465371221094280. PMID: 35544414
Pneumatosis Intestinalis and Anorexia Nervosa.
Gibson D, Watters A, Pieracci F, Reiss R, Mehler PS
Surg Infect (Larchmt) 2022 Sep;23(7):661-666. Epub 2022 Aug 16 doi: 10.1089/sur.2022.127. PMID: 35969259
GASTROINTESTINAL COMPLICATIONS OF CORONAVIRUS DISEASE (COVID-19).
Ribeiro-Junior MAF, Augusto SS, Elias YGB, Costa CTK, Néder PR
Arq Bras Cir Dig 2022;34(3):e1620. Epub 2022 Jan 5 doi: 10.1590/0102-672020210002e1620. PMID: 35019132Free PMC Article
Pneumatosis intestinalis in the pediatric oncology population: An 11-year retrospective review at Memorial Sloan Kettering Cancer Center.
Bailey KA, Kodikara H, Mauguen A, Price A, LaQuaglia M, Boulad F
Pediatr Blood Cancer 2022 Jul;69(7):e29539. Epub 2021 Dec 28 doi: 10.1002/pbc.29539. PMID: 34962703Free PMC Article
Role of Abdominal US in Diagnosis of NEC.
Kim JH
Clin Perinatol 2019 Mar;46(1):119-127. Epub 2018 Dec 20 doi: 10.1016/j.clp.2018.10.006. PMID: 30771813

Therapy

Prednisolone induced pneumatosis coli and pneumoperitoneum.
Goh SSN, Shelat V
World J Gastroenterol 2022 Jul 28;28(28):3739-3742. doi: 10.3748/wjg.v28.i28.3739. PMID: 36161037Free PMC Article
Pneumatosis intestinalis in COVID-19.
Meini S, Zini C, Passaleva MT, Frullini A, Fusco F, Carpi R, Piani F
BMJ Open Gastroenterol 2020 Jun;7(1) doi: 10.1136/bmjgast-2020-000434. PMID: 32522754Free PMC Article
Pneumatosis Intestinalis After Molecular-Targeted Therapy.
Chaudhry NS, Bi WL, Gupta S, Keraliya A, Shimizu N, Chiocca EA
World Neurosurg 2019 May;125:312-315. Epub 2019 Feb 11 doi: 10.1016/j.wneu.2019.01.225. PMID: 30763745
What next in necrotizing enterocolitis?
Yurdakök M
Turk J Pediatr 2008 Jan-Feb;50(1):1-11. PMID: 18365584
Necrotizing enterocolitis.
Frantz ID 3rd, L'heureux P, Engel RR, Hunt CE
J Pediatr 1975 Feb;86(2):259-63. doi: 10.1016/s0022-3476(75)80485-9. PMID: 803385

Prognosis

Clinical outcomes and gestational age based prediction of pneumatosis intestinalis in preterm infants with necrotizing enterocolitis.
Garg PM, Paschal JL, Ansari MAY, Sonani H, Grey C, Chan S, Varshney N, Hillegass W
J Neonatal Perinatal Med 2022;15(4):803-812. doi: 10.3233/NPM-210971. PMID: 35811540Free PMC Article
Pneumatosis intestinalis and porto-mesenteric venous gas: a multicenter study.
Della Seta M, Kloeckner R, Pinto Dos Santos D, Walter-Rittel TC, Hahn F, Henze J, Gropp A, Pratschke J, Hamm B, Geisel D, Auer TA
BMC Med Imaging 2021 Aug 24;21(1):129. doi: 10.1186/s12880-021-00651-y. PMID: 34429069Free PMC Article
Clinical Predictors and Outcomes for Recurrent Pneumatosis Intestinalis in Children: A Case Control Study.
Ta AG, Farrell M, Dillman JR, Trout AT
J Pediatr Gastroenterol Nutr 2021 Oct 1;73(4):e87-e93. doi: 10.1097/MPG.0000000000003216. PMID: 34183613Free PMC Article
Pneumatosis intestinalis.
Saul T, Palamidessi N
J Emerg Med 2011 May;40(5):545-6. Epub 2009 Mar 9 doi: 10.1016/j.jemermed.2008.10.019. PMID: 19272737
Necrotizing enterocolitis.
Frantz ID 3rd, L'heureux P, Engel RR, Hunt CE
J Pediatr 1975 Feb;86(2):259-63. doi: 10.1016/s0022-3476(75)80485-9. PMID: 803385

Clinical prediction guides

Prednisolone induced pneumatosis coli and pneumoperitoneum.
Goh SSN, Shelat V
World J Gastroenterol 2022 Jul 28;28(28):3739-3742. doi: 10.3748/wjg.v28.i28.3739. PMID: 36161037Free PMC Article
Clinical outcomes and gestational age based prediction of pneumatosis intestinalis in preterm infants with necrotizing enterocolitis.
Garg PM, Paschal JL, Ansari MAY, Sonani H, Grey C, Chan S, Varshney N, Hillegass W
J Neonatal Perinatal Med 2022;15(4):803-812. doi: 10.3233/NPM-210971. PMID: 35811540Free PMC Article
Clinical Predictors and Outcomes for Recurrent Pneumatosis Intestinalis in Children: A Case Control Study.
Ta AG, Farrell M, Dillman JR, Trout AT
J Pediatr Gastroenterol Nutr 2021 Oct 1;73(4):e87-e93. doi: 10.1097/MPG.0000000000003216. PMID: 34183613Free PMC Article
Machine learning for the prediction of pathologic pneumatosis intestinalis.
Clancy K, Dadashzadeh ER, Handzel R, Rieser C, Moses JB, Rosenblum L, Wu S
Surgery 2021 Sep;170(3):797-805. Epub 2021 Apr 27 doi: 10.1016/j.surg.2021.03.049. PMID: 33926706Free PMC Article
Clinical characteristics of patients with pneumatosis intestinalis.
Fujii M, Yamashita S, Tashiro J, Tanaka M, Takenaka Y, Yamasaki K, Masaki Y
ANZ J Surg 2021 Sep;91(9):1826-1831. Epub 2021 Apr 6 doi: 10.1111/ans.16772. PMID: 33825311

Recent systematic reviews

Radiological predictive factors of transmural intestinal necrosis in acute mesenteric ischemia: systematic review and meta-analysis.
Zeng Y, Yang F, Hu X, Zhu F, Chen W, Lin W
Eur Radiol 2023 Apr;33(4):2792-2799. Epub 2022 Nov 30 doi: 10.1007/s00330-022-09258-5. PMID: 36449058
Gastrointestinal Dysfunction Criteria in Critically Ill Children: The PODIUM Consensus Conference.
Typpo KV, Irving SY, Prince JM, Pathan N, Brown AM; Pediatric Organ Dysfunction Information Update Mandate (PODIUM) Collaborative
Pediatrics 2022 Jan 1;149(1 Suppl 1):S53-S58. doi: 10.1542/peds.2021-052888H. PMID: 34970680Free PMC Article
Abdominal imaging findings in patients with SARS-CoV-2 infection: a scoping review.
Lui K, Wilson MP, Low G
Abdom Radiol (NY) 2021 Mar;46(3):1249-1255. Epub 2020 Sep 14 doi: 10.1007/s00261-020-02739-5. PMID: 32926211Free PMC Article
Bowel ultrasound for predicting surgical management of necrotizing enterocolitis: a systematic review and meta-analysis.
Cuna AC, Reddy N, Robinson AL, Chan SS
Pediatr Radiol 2018 May;48(5):658-666. Epub 2017 Dec 19 doi: 10.1007/s00247-017-4056-x. PMID: 29260286Free PMC Article

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