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Child Development Disorders, Pervasive

MedGen UID:
887
•Concept ID:
C0008074
•
Mental or Behavioral Dysfunction
Synonym: Pervasive Child Development Disorders

Definition

Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements. [from MeSH]

Professional guidelines

PubMed

Risk factors, diagnosis, prognosis and treatment of autism.
Styles M, Alsharshani D, Samara M, Alsharshani M, Khattab A, Qoronfleh MW, Al-Dewik NI
Front Biosci (Landmark Ed) 2020 Jun 1;25(9):1682-1717. doi: 10.2741/4873. PMID: 32472753
Autism Spectrum Disorders and ADHD: Overlapping Phenomenology, Diagnostic Issues, and Treatment Considerations.
Antshel KM, Russo N
Curr Psychiatry Rep 2019 Mar 22;21(5):34. doi: 10.1007/s11920-019-1020-5. PMID: 30903299
Autism Spectrum Disorder: Primary Care Principles.
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089

Recent clinical studies

Etiology

From the genetic architecture to synaptic plasticity in autism spectrum disorder.
Bourgeron T
Nat Rev Neurosci 2015 Sep;16(9):551-63. doi: 10.1038/nrn3992. PMID: 26289574
How nutritional status, diet and dietary supplements can affect autism. A review.
Kawicka A, Regulska-Ilow B
Rocz Panstw Zakl Hig 2013;64(1):1-12. PMID: 23789306
Sex differences in autism spectrum disorders.
Werling DM, Geschwind DH
Curr Opin Neurol 2013 Apr;26(2):146-53. doi: 10.1097/WCO.0b013e32835ee548. PMID: 23406909Free PMC Article
Effectiveness of sensory integration interventions in children with autism spectrum disorders: a pilot study.
Pfeiffer BA, Koenig K, Kinnealey M, Sheppard M, Henderson L
Am J Occup Ther 2011 Jan-Feb;65(1):76-85. doi: 10.5014/ajot.2011.09205. PMID: 21309374Free PMC Article
Autism spectrum disorders.
Faras H, Al Ateeqi N, Tidmarsh L
Ann Saudi Med 2010 Jul-Aug;30(4):295-300. doi: 10.4103/0256-4947.65261. PMID: 20622347Free PMC Article

Diagnosis

From the genetic architecture to synaptic plasticity in autism spectrum disorder.
Bourgeron T
Nat Rev Neurosci 2015 Sep;16(9):551-63. doi: 10.1038/nrn3992. PMID: 26289574
Autism: cause factors, early diagnosis and therapies.
Bhat S, Acharya UR, Adeli H, Bairy GM, Adeli A
Rev Neurosci 2014;25(6):841-50. doi: 10.1515/revneuro-2014-0056. PMID: 25222596
Autism and nutrition: the role of the gut-brain axis.
van De Sande MM, van Buul VJ, Brouns FJ
Nutr Res Rev 2014 Dec;27(2):199-214. Epub 2014 Jul 8 doi: 10.1017/S0954422414000110. PMID: 25004237
"Autism-plus" spectrum disorders: intersection with psychosis and the schizophrenia spectrum.
Cochran DM, Dvir Y, Frazier JA
Child Adolesc Psychiatr Clin N Am 2013 Oct;22(4):609-27. Epub 2013 Jun 18 doi: 10.1016/j.chc.2013.04.005. PMID: 24012076
Animal-assisted intervention for autism spectrum disorder: a systematic literature review.
O'Haire ME
J Autism Dev Disord 2013 Jul;43(7):1606-22. doi: 10.1007/s10803-012-1707-5. PMID: 23124442

Therapy

The Effects of Structured Physical Activity Program on Social Interaction and Communication for Children with Autism.
Zhao M, Chen S
Biomed Res Int 2018;2018:1825046. Epub 2018 Jan 15 doi: 10.1155/2018/1825046. PMID: 29568743Free PMC Article
Autism Spectrum Disorder: Primary Care Principles.
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089
Sulforaphane treatment of autism spectrum disorder (ASD).
Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW
Proc Natl Acad Sci U S A 2014 Oct 28;111(43):15550-5. Epub 2014 Oct 13 doi: 10.1073/pnas.1416940111. PMID: 25313065Free PMC Article
Music therapy for people with autism spectrum disorder.
Geretsegger M, Elefant C, Mössler KA, Gold C
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD004381. doi: 10.1002/14651858.CD004381.pub3. PMID: 24936966Free PMC Article
Melatonin in autism spectrum disorders: a systematic review and meta-analysis.
Rossignol DA, Frye RE
Dev Med Child Neurol 2011 Sep;53(9):783-792. Epub 2011 Apr 19 doi: 10.1111/j.1469-8749.2011.03980.x. PMID: 21518346

Prognosis

Autism Spectrum Disorder: Primary Care Principles.
Sanchack KE, Thomas CA
Am Fam Physician 2016 Dec 15;94(12):972-979. PMID: 28075089
Practice parameter for the assessment and treatment of children and adolescents with autism spectrum disorder.
Volkmar F, Siegel M, Woodbury-Smith M, King B, McCracken J, State M; American Academy of Child and Adolescent Psychiatry (AACAP) Committee on Quality Issues (CQI)
J Am Acad Child Adolesc Psychiatry 2014 Feb;53(2):237-57. doi: 10.1016/j.jaac.2013.10.013. PMID: 24472258
Validation of the modified checklist for Autism in toddlers, revised with follow-up (M-CHAT-R/F).
Robins DL, Casagrande K, Barton M, Chen CM, Dumont-Mathieu T, Fein D
Pediatrics 2014 Jan;133(1):37-45. Epub 2013 Dec 23 doi: 10.1542/peds.2013-1813. PMID: 24366990Free PMC Article
How nutritional status, diet and dietary supplements can affect autism. A review.
Kawicka A, Regulska-Ilow B
Rocz Panstw Zakl Hig 2013;64(1):1-12. PMID: 23789306
Prenatal valproate exposure and risk of autism spectrum disorders and childhood autism.
Christensen J, Grønborg TK, Sørensen MJ, Schendel D, Parner ET, Pedersen LH, Vestergaard M
JAMA 2013 Apr 24;309(16):1696-703. doi: 10.1001/jama.2013.2270. PMID: 23613074Free PMC Article

Clinical prediction guides

Childhood autism spectrum disorders with and without epilepsy: clinical implications.
Shubrata KS, Sinha S, Seshadri SP, Girimaji S, Subbakrishna DK, Srinath S
J Child Neurol 2015 Mar;30(4):476-82. Epub 2014 Jul 17 doi: 10.1177/0883073814540521. PMID: 25038126
Association of social and cognitive impairment and biomarkers in autism spectrum disorders.
Alabdali A, Al-Ayadhi L, El-Ansary A
J Neuroinflammation 2014 Jan 8;11:4. doi: 10.1186/1742-2094-11-4. PMID: 24400970Free PMC Article
Sex differences in autism spectrum disorders.
Werling DM, Geschwind DH
Curr Opin Neurol 2013 Apr;26(2):146-53. doi: 10.1097/WCO.0b013e32835ee548. PMID: 23406909Free PMC Article
How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders?
Dworzynski K, Ronald A, Bolton P, Happé F
J Am Acad Child Adolesc Psychiatry 2012 Aug;51(8):788-97. Epub 2012 Jun 26 doi: 10.1016/j.jaac.2012.05.018. PMID: 22840550
Effectiveness of sensory integration interventions in children with autism spectrum disorders: a pilot study.
Pfeiffer BA, Koenig K, Kinnealey M, Sheppard M, Henderson L
Am J Occup Ther 2011 Jan-Feb;65(1):76-85. doi: 10.5014/ajot.2011.09205. PMID: 21309374Free PMC Article

Recent systematic reviews

Music therapy for people with autism spectrum disorder.
Geretsegger M, Elefant C, Mössler KA, Gold C
Cochrane Database Syst Rev 2014 Jun 17;2014(6):CD004381. doi: 10.1002/14651858.CD004381.pub3. PMID: 24936966Free PMC Article
Food selectivity in autism spectrum disorders: a systematic review.
Marí-Bauset S, Zazpe I, Mari-Sanchis A, Llopis-González A, Morales-Suárez-Varela M
J Child Neurol 2014 Nov;29(11):1554-61. Epub 2013 Oct 4 doi: 10.1177/0883073813498821. PMID: 24097852
Applied behavior analysis and autism spectrum disorders: literature review.
Fernandes FD, Amato CA
Codas 2013;25(3):289-96. doi: 10.1590/s2317-17822013000300016. PMID: 24408342
Global prevalence of autism and other pervasive developmental disorders.
Elsabbagh M, Divan G, Koh YJ, Kim YS, Kauchali S, Marcín C, Montiel-Nava C, Patel V, Paula CS, Wang C, Yasamy MT, Fombonne E
Autism Res 2012 Jun;5(3):160-79. Epub 2012 Apr 11 doi: 10.1002/aur.239. PMID: 22495912Free PMC Article
Melatonin in autism spectrum disorders: a systematic review and meta-analysis.
Rossignol DA, Frye RE
Dev Med Child Neurol 2011 Sep;53(9):783-792. Epub 2011 Apr 19 doi: 10.1111/j.1469-8749.2011.03980.x. PMID: 21518346

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