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Malignant Osteoclastic Giant Cell-Rich Tumor of Bone

MedGen UID:
887074
Concept ID:
C4054576
Neoplastic Process

Definition

A giant cell tumor that arises from the bone and is characterized by the presence of a malignant cellular component. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMalignant Osteoclastic Giant Cell-Rich Tumor of Bone

Professional guidelines

Recent clinical studies

Etiology

Karczewski D, Gonzalez MR, Bedi A, Ready JE, Anderson ME, Lozano-Calderon SA
J Surg Oncol 2023 Oct;128(5):877-890. Epub 2023 Jun 9 doi: 10.1002/jso.27368. PMID: 37292033
Panagopoulos I, Andersen K, Gorunova L, Lund-Iversen M, Lobmaier I, Heim S
Cancer Genomics Proteomics 2022 Mar-Apr;19(2):163-177. doi: 10.21873/cgp.20312. PMID: 35181586Free PMC Article
Lee JC, Huang HY
Head Neck Pathol 2020 Mar;14(1):97-108. Epub 2020 Jan 16 doi: 10.1007/s12105-019-01086-2. PMID: 31950466Free PMC Article
Lipplaa A, Dijkstra S, Gelderblom H
Curr Opin Oncol 2019 Jul;31(4):329-335. doi: 10.1097/CCO.0000000000000529. PMID: 30844887Free PMC Article
Gamage NM, Kashima TG, McNally MA, Gibbons CL, Smith R, Ostlere SJ, Athanasou NA
Skeletal Radiol 2013 Apr;42(4):595-9. Epub 2012 Dec 29 doi: 10.1007/s00256-012-1558-3. PMID: 23275027

Diagnosis

Weigelt MA, Azzato EM, Habermehl GK, Billings SD, Ko JS, Fritchie KJ
J Cutan Pathol 2023 Nov;50(11):977-982. Epub 2023 Jul 26 doi: 10.1111/cup.14497. PMID: 37496152
Kovacs SK, Manassaporn A, Nielsen GP, Hung YP
Histopathology 2023 May;82(6):794-811. Epub 2022 Dec 16 doi: 10.1111/his.14845. PMID: 36424903
Al-Dasuqi K, Cheng R, Moran J, Irshaid L, Maloney E, Porrino J
Skeletal Radiol 2023 Apr;52(4):671-685. Epub 2022 Nov 3 doi: 10.1007/s00256-022-04221-3. PMID: 36326880
Jager L, Johnson DN, Sukhanova M, Streich L, Chapa AR, Alexiev BA
Pathol Res Pract 2022 Mar;231:153777. Epub 2022 Jan 21 doi: 10.1016/j.prp.2022.153777. PMID: 35091179
Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article

Therapy

Lipplaa A, Schreuder WH, Pichardo SEC, Gelderblom H
Oncologist 2023 Nov 2;28(11):1005-e1104. doi: 10.1093/oncolo/oyad196. PMID: 37449658Free PMC Article
Suster DI, Kurzawa P, Neyaz A, Jarzembowski JA, Lozano-Calderon S, Raskin K, Schwab J, Choy E, Chebib I, Deshpande V
Am J Surg Pathol 2020 Dec;44(12):1581-1590. doi: 10.1097/PAS.0000000000001568. PMID: 32826531
Lipplaa A, Dijkstra S, Gelderblom H
Curr Opin Oncol 2019 Jul;31(4):329-335. doi: 10.1097/CCO.0000000000000529. PMID: 30844887Free PMC Article
Yamamoto H, Iwasaki T, Yamada Y, Matsumoto Y, Otsuka H, Yoshimoto M, Kohashi K, Taguchi K, Yokoyama R, Nakashima Y, Oda Y
Hum Pathol 2018 Mar;73:41-50. Epub 2017 Dec 12 doi: 10.1016/j.humpath.2017.11.020. PMID: 29241742
Chow LT
Virchows Arch 2016 Jun;468(6):741-55. Epub 2016 Mar 22 doi: 10.1007/s00428-016-1926-9. PMID: 27003154

Prognosis

Weigelt MA, Azzato EM, Habermehl GK, Billings SD, Ko JS, Fritchie KJ
J Cutan Pathol 2023 Nov;50(11):977-982. Epub 2023 Jul 26 doi: 10.1111/cup.14497. PMID: 37496152
Wang A, Maloney E, Al-Dasuqi K, Irshaid L, Ahmed A, Haims A, Porrino J
Skeletal Radiol 2023 Aug;52(8):1443-1463. Epub 2023 Jan 19 doi: 10.1007/s00256-023-04286-8. PMID: 36656343
Al-Dasuqi K, Cheng R, Moran J, Irshaid L, Maloney E, Porrino J
Skeletal Radiol 2023 Apr;52(4):671-685. Epub 2022 Nov 3 doi: 10.1007/s00256-022-04221-3. PMID: 36326880
Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Gamage NM, Kashima TG, McNally MA, Gibbons CL, Smith R, Ostlere SJ, Athanasou NA
Skeletal Radiol 2013 Apr;42(4):595-9. Epub 2012 Dec 29 doi: 10.1007/s00256-012-1558-3. PMID: 23275027

Clinical prediction guides

Karczewski D, Gonzalez MR, Bedi A, Ready JE, Anderson ME, Lozano-Calderon SA
J Surg Oncol 2023 Oct;128(5):877-890. Epub 2023 Jun 9 doi: 10.1002/jso.27368. PMID: 37292033
Miskad UA, Syamsul F, Dahlan H, Sungowati NK, Achmad D, Johan MP
Asian Pac J Cancer Prev 2023 May 1;24(5):1737-1741. doi: 10.31557/APJCP.2023.24.5.1737. PMID: 37247296Free PMC Article
Kamble A, Hui M, Rao KN, Narayanan R, Reddy BR, Uppin SG, Chandrasekhar P
Indian J Pathol Microbiol 2022 Jul-Sep;65(3):617-629. doi: 10.4103/ijpm.ijpm_265_21. PMID: 35900490
Ventura L, Petrella E, Piciucchi S, Cilli E, Luiselli D, Feeney RNM, Traversari M
Virchows Arch 2021 Dec;479(6):1255-1261. Epub 2021 Aug 30 doi: 10.1007/s00428-021-03192-5. PMID: 34462806Free PMC Article
Santana LADM, Felix FA, de Arruda JAA, da Silva LP, Brito ÉAC, Takeshita WM, Trento CL
Oral Surg Oral Med Oral Pathol Oral Radiol 2021 May;131(5):e163-e169. Epub 2020 Oct 17 doi: 10.1016/j.oooo.2020.10.009. PMID: 33187945

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