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Nephrotic Syndrome - Syphilis Associated

MedGen UID:
889603
•Concept ID:
C4054364
•
Disease or Syndrome

Definition

Nephrotic syndrome associated with a syphilis infection. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVNephrotic Syndrome - Syphilis Associated

Recent clinical studies

Etiology

Scrub typhus: A rare cause of secondary nephrotic syndrome.
Singh A, Anjali A, Prasad R, Prakash P, Mishra OP
J Vector Borne Dis 2021 Jan-Mar;58(1):94-96. doi: 10.4103/0972-9062.321744. PMID: 34818870
Duodenal Schwannoma as a Rare Association With Membranous Nephropathy: A Case Report.
Zhang Z, Gong T, Rennke HG, Hayashi R
Am J Kidney Dis 2019 Feb;73(2):278-280. Epub 2018 Nov 16 doi: 10.1053/j.ajkd.2018.09.003. PMID: 30454884
Renal problems in black South African children.
Thomson PD
Pediatr Nephrol 1997 Aug;11(4):508-12. doi: 10.1007/s004670050330. PMID: 9260259
Membranous glomerulonephropathy in childhood.
Wiggelinkhuizen J, Sinclair-Smith C
S Afr Med J 1987 Aug 1;72(3):184-7. PMID: 3603311

Diagnosis

Secondary Syphilis Associated Nephrotic Syndrome.
Lin CC, Pan CF, Chen TY, Tsai JD
J Pediatr 2021 Aug;235:297-298. Epub 2021 Apr 20 doi: 10.1016/j.jpeds.2021.04.009. PMID: 33862026
Secondary Syphilis Associated with Membranous Nephropathy and Acute Hepatitis in a Patient with HIV: A Case Report.
Zhang Z, Hever A, Bhasin N, Kujubu DA
Perm J 2018;22:17-062. doi: 10.7812/TPP/17-062. PMID: 29236656Free PMC Article
The etiology of congenital nephrotic syndrome: current status and challenges.
Wang JJ, Mao JH
World J Pediatr 2016 May;12(2):149-58. Epub 2016 Mar 9 doi: 10.1007/s12519-016-0009-y. PMID: 26961288
Secondary syphilis and the nephrotic syndrome.
Hunte W, al-Ghraoui F, Cohen RJ
J Am Soc Nephrol 1993 Jan;3(7):1351-5. doi: 10.1681/ASN.V371351. PMID: 8439646
Membranous nephropathy: an overview.
Salomon MI, Hsu K, Tchertkoff V
J Am Geriatr Soc 1975 Dec;23(12):535-40. doi: 10.1111/j.1532-5415.1975.tb00628.x. PMID: 1206187

Therapy

Rituximab-induced mild encephalopathy with a reversible splenial lesion syndrome (MERS): An adverse effect to add to the list.
Thabet M, Atig A, Fathallah N, Guiga A, Ben Yahia W, Ouni B, Ghannouchi N
Br J Clin Pharmacol 2022 Jun;88(6):2969-2972. Epub 2022 Feb 7 doi: 10.1111/bcp.15189. PMID: 34921445
Secondary Syphilis Associated Nephrotic Syndrome.
Lin CC, Pan CF, Chen TY, Tsai JD
J Pediatr 2021 Aug;235:297-298. Epub 2021 Apr 20 doi: 10.1016/j.jpeds.2021.04.009. PMID: 33862026
Secondary syphilis: a rare cause of nephrotic syndrome.
Janeiro S, Fernandes AM, Lopes P, Pedroso E
BMJ Case Rep 2014 Jul 8;2014 doi: 10.1136/bcr-2013-201473. PMID: 25006049Free PMC Article
Mercury and the kidney.
George CR
J Nephrol 2011 May-Jun;24 Suppl 17:S126-32. doi: 10.5301/JN.2011.6486. PMID: 21614794
Membranous nephropathy: an overview.
Salomon MI, Hsu K, Tchertkoff V
J Am Geriatr Soc 1975 Dec;23(12):535-40. doi: 10.1111/j.1532-5415.1975.tb00628.x. PMID: 1206187

Prognosis

Duodenal Schwannoma as a Rare Association With Membranous Nephropathy: A Case Report.
Zhang Z, Gong T, Rennke HG, Hayashi R
Am J Kidney Dis 2019 Feb;73(2):278-280. Epub 2018 Nov 16 doi: 10.1053/j.ajkd.2018.09.003. PMID: 30454884
Hiv-associated nephropathy occurring before HIV antibody seroconversion.
Levin ML, Palella F, Shah S, Lerma E, Butter J, Kanwar YS
Am J Kidney Dis 2001 May;37(5):E39. doi: 10.1016/s0272-6386(05)90003-6. PMID: 11325704
Secondary syphilis and the nephrotic syndrome.
Hunte W, al-Ghraoui F, Cohen RJ
J Am Soc Nephrol 1993 Jan;3(7):1351-5. doi: 10.1681/ASN.V371351. PMID: 8439646
The variety of clinical and histopathologic presentations of glomerulonephritis associated with latent syphilis.
Hruby Z, Kuźniar J, Rabczyński J, Bogucki J, Steciwko A, Weyde W
Int Urol Nephrol 1992;24(5):541-7. doi: 10.1007/BF02550123. PMID: 1459832
Membranous glomerulonephropathy in childhood.
Wiggelinkhuizen J, Sinclair-Smith C
S Afr Med J 1987 Aug 1;72(3):184-7. PMID: 3603311

Clinical prediction guides

Mercury and the kidney.
George CR
J Nephrol 2011 May-Jun;24 Suppl 17:S126-32. doi: 10.5301/JN.2011.6486. PMID: 21614794
Membranous nephropathy associated with chronic hepatitis B occurring in a short period after acute hepatitis B virus infection.
Nakahara K, Takahashi H, Okuse C, Shigefuku R, Yamada N, Murao M, Matsunaga K, Koike J, Yotsuyanagi H, Suzuki M, Kimura K, Itoh F
Intern Med 2010;49(5):383-8. Epub 2010 Mar 1 doi: 10.2169/internalmedicine.49.2812. PMID: 20190469
Respiratory chain deficiency presenting as congenital nephrotic syndrome.
Goldenberg A, Ngoc LH, Thouret MC, Cormier-Daire V, Gagnadoux MF, Chrétien D, Lefrançois C, Geromel V, Rötig A, Rustin P, Munnich A, Paquis V, Antignac C, Gubler MC, Niaudet P, de Lonlay P, Bérard E
Pediatr Nephrol 2005 Apr;20(4):465-9. Epub 2005 Jan 29 doi: 10.1007/s00467-004-1725-4. PMID: 15682315
The variety of clinical and histopathologic presentations of glomerulonephritis associated with latent syphilis.
Hruby Z, Kuźniar J, Rabczyński J, Bogucki J, Steciwko A, Weyde W
Int Urol Nephrol 1992;24(5):541-7. doi: 10.1007/BF02550123. PMID: 1459832

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