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Borderline Ovarian Serous Tumor/Atypical Proliferative Ovarian Serous Tumor

MedGen UID:
890658
•Concept ID:
C4053505
•
Neoplastic Process

Definition

A non-invasive serous neoplasm that arises from the ovary and shows greater cellular proliferation and cytologic atypia as compared to benign ovarian serous tumors, but less as compared to low-grade ovarian serous carcinoma. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVBorderline Ovarian Serous Tumor/Atypical Proliferative Ovarian Serous Tumor

Recent clinical studies

Prognosis

Late recurrence of pStage 1 low-grade serous ovarian tumor presenting as a symptomatic bone metastasis: a case report.
Kubo C, Nagata S, Fukuda T, Kano R, Tanaka T, Nakanishi K, Ohsawa M, Nakatsuka SI
Diagn Pathol 2018 Jun 30;13(1):43. doi: 10.1186/s13000-018-0720-1. PMID: 29960592Free PMC Article
KRAS mutation of extraovarian implants of serous borderline tumor: prognostic indicator for adverse clinical outcome.
Zuo T, Wong S, Buza N, Hui P
Mod Pathol 2018 Feb;31(2):350-357. Epub 2017 Oct 13 doi: 10.1038/modpathol.2017.121. PMID: 29027536
Mutational analysis of K-ras segregates ovarian serous carcinomas into two types: invasive MPSC (low-grade tumor) and conventional serous carcinoma (high-grade tumor).
Singer G, Shih IeM, Truskinovsky A, Umudum H, Kurman RJ
Int J Gynecol Pathol 2003 Jan;22(1):37-41. doi: 10.1097/00004347-200301000-00009. PMID: 12496696

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