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Abnormality of body weight

MedGen UID:
892367
•Concept ID:
C4025357
•
Finding
Synonym: Abnormality of habitus
 
HPO: HP:0004323

Definition

An abnormal increase or decrease of weight or an abnormal distribution of mass in the body. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAbnormality of body weight

Professional guidelines

PubMed

Non-alcoholic fatty liver disease (NAFLD): a review of pathophysiology, clinical management and effects of weight loss.
Pouwels S, Sakran N, Graham Y, Leal A, Pintar T, Yang W, Kassir R, Singhal R, Mahawar K, Ramnarain D
BMC Endocr Disord 2022 Mar 14;22(1):63. doi: 10.1186/s12902-022-00980-1. PMID: 35287643Free PMC Article
Polycystic ovary syndrome: definition, aetiology, diagnosis and treatment.
Escobar-Morreale HF
Nat Rev Endocrinol 2018 May;14(5):270-284. Epub 2018 Mar 23 doi: 10.1038/nrendo.2018.24. PMID: 29569621
Clinical Practice Guideline for Screening and Management of High Blood Pressure in Children and Adolescents.
Flynn JT, Kaelber DC, Baker-Smith CM, Blowey D, Carroll AE, Daniels SR, de Ferranti SD, Dionne JM, Falkner B, Flinn SK, Gidding SS, Goodwin C, Leu MG, Powers ME, Rea C, Samuels J, Simasek M, Thaker VV, Urbina EM; SUBCOMMITTEE ON SCREENING AND MANAGEMENT OF HIGH BLOOD PRESSURE IN CHILDREN
Pediatrics 2017 Sep;140(3) Epub 2017 Aug 21 doi: 10.1542/peds.2017-1904. PMID: 28827377

Recent clinical studies

Etiology

Effects of Overweight and Obesity in Pregnancy on Health of the Offspring.
Dow ML, Szymanski LM
Endocrinol Metab Clin North Am 2020 Jun;49(2):251-263. Epub 2020 Apr 16 doi: 10.1016/j.ecl.2020.02.005. PMID: 32418588
The Risks Associated With Obesity in Pregnancy.
Stubert J, Reister F, Hartmann S, Janni W
Dtsch Arztebl Int 2018 Apr 20;115(16):276-283. doi: 10.3238/arztebl.2018.0276. PMID: 29739495Free PMC Article
Long-term consequences of obesity on female fertility and the health of the offspring.
Chandrasekaran S, Neal-Perry G
Curr Opin Obstet Gynecol 2017 Jun;29(3):180-187. doi: 10.1097/GCO.0000000000000364. PMID: 28448277Free PMC Article
Preconception care: nutritional risks and interventions.
Dean SV, Lassi ZS, Imam AM, Bhutta ZA
Reprod Health 2014 Sep 26;11 Suppl 3(Suppl 3):S3. doi: 10.1186/1742-4755-11-S3-S3. PMID: 25415364Free PMC Article
Obesity and the risk and detection of fetal malformations.
Racusin D, Stevens B, Campbell G, Aagaard KM
Semin Perinatol 2012 Jun;36(3):213-21. doi: 10.1053/j.semperi.2012.05.001. PMID: 22713503Free PMC Article

Diagnosis

Baraitser-Winter cerebrofrontofacial syndrome.
Yates TM, Turner CL, Firth HV, Berg J, Pilz DT
Clin Genet 2017 Jul;92(1):3-9. Epub 2016 Nov 30 doi: 10.1111/cge.12864. PMID: 27625340
Obesity and the challenges of ultrasound fetal abnormality diagnosis.
Tsai PJ, Loichinger M, Zalud I
Best Pract Res Clin Obstet Gynaecol 2015 Apr;29(3):320-7. Epub 2014 Oct 16 doi: 10.1016/j.bpobgyn.2014.08.011. PMID: 25457860
Preconception care: nutritional risks and interventions.
Dean SV, Lassi ZS, Imam AM, Bhutta ZA
Reprod Health 2014 Sep 26;11 Suppl 3(Suppl 3):S3. doi: 10.1186/1742-4755-11-S3-S3. PMID: 25415364Free PMC Article
Errors in prenatal diagnosis.
Anumba DO
Best Pract Res Clin Obstet Gynaecol 2013 Aug;27(4):537-48. Epub 2013 May 30 doi: 10.1016/j.bpobgyn.2013.04.007. PMID: 23725900
Overgrowth syndromes.
Neylon OM, Werther GA, Sabin MA
Curr Opin Pediatr 2012 Aug;24(4):505-11. doi: 10.1097/MOP.0b013e3283558995. PMID: 22705997

Therapy

Efficacy and safety of setmelanotide, a melanocortin-4 receptor agonist, in patients with Bardet-Biedl syndrome and Alström syndrome: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial with an open-label period.
Haqq AM, Chung WK, Dollfus H, Haws RM, Martos-Moreno GÁ, Poitou C, Yanovski JA, Mittleman RS, Yuan G, Forsythe E, Clément K, Argente J
Lancet Diabetes Endocrinol 2022 Dec;10(12):859-868. Epub 2022 Nov 7 doi: 10.1016/S2213-8587(22)00277-7. PMID: 36356613Free PMC Article
Clinical Opinion: The diagnosis and management of suspected fetal growth restriction: an evidence-based approach.
Lees CC, Romero R, Stampalija T, Dall'Asta A, DeVore GA, Prefumo F, Frusca T, Visser GHA, Hobbins JC, Baschat AA, Bilardo CM, Galan HL, Campbell S, Maulik D, Figueras F, Lee W, Unterscheider J, Valensise H, Da Silva Costa F, Salomon LJ, Poon LC, Ferrazzi E, Mari G, Rizzo G, Kingdom JC, Kiserud T, Hecher K
Am J Obstet Gynecol 2022 Mar;226(3):366-378. Epub 2022 Jan 10 doi: 10.1016/j.ajog.2021.11.1357. PMID: 35026129Free PMC Article
Selection of Antiobesity Medications Based on Phenotypes Enhances Weight Loss: A Pragmatic Trial in an Obesity Clinic.
Acosta A, Camilleri M, Abu Dayyeh B, Calderon G, Gonzalez D, McRae A, Rossini W, Singh S, Burton D, Clark MM
Obesity (Silver Spring) 2021 Apr;29(4):662-671. doi: 10.1002/oby.23120. PMID: 33759389Free PMC Article
Evidences from Clinical Trials in Down Syndrome: Diet, Exercise and Body Composition.
Martínez-Espinosa RM, Molina Vila MD, Reig García-Galbis M
Int J Environ Res Public Health 2020 Jun 16;17(12) doi: 10.3390/ijerph17124294. PMID: 32560141Free PMC Article
Preconception care: nutritional risks and interventions.
Dean SV, Lassi ZS, Imam AM, Bhutta ZA
Reprod Health 2014 Sep 26;11 Suppl 3(Suppl 3):S3. doi: 10.1186/1742-4755-11-S3-S3. PMID: 25415364Free PMC Article

Prognosis

Comorbidities in children with intellectual disabilities.
Markovic-Jovanovic SR, Milovanovic JD, Jovanovic AN, Zivkovic JB, Balovic AD, Nickovic V, Vasic MZ, Ristic MZ
Birth Defects Res 2020 Jan 1;112(1):54-61. Epub 2019 Sep 10 doi: 10.1002/bdr2.1587. PMID: 31502761
Cat eye syndrome.
Sharma D, Murki S, Pratap T, Vasikarla M
BMJ Case Rep 2014 May 19;2014 doi: 10.1136/bcr-2014-203923. PMID: 24842361Free PMC Article
Pregnancy after bariatric surgery.
Kominiarek MA
Obstet Gynecol Clin North Am 2010 Jun;37(2):305-20. doi: 10.1016/j.ogc.2010.02.010. PMID: 20685555
Hirschsprung-associated congenital anomalies.
Sarioglu A, Tanyel FC, Büyükpamukçu N, Hiçsönmez A
Eur J Pediatr Surg 1997 Dec;7(6):331-7. doi: 10.1055/s-2008-1071186. PMID: 9493983
The contribution of low birth weight to infant mortality and childhood morbidity.
McCormick MC
N Engl J Med 1985 Jan 10;312(2):82-90. doi: 10.1056/NEJM198501103120204. PMID: 3880598

Clinical prediction guides

Mammalian target of rapamycin inhibition impacts energy homeostasis and induces sex-specific body weight loss in humans.
Mannaa M, Pfennigwerth P, Fielitz J, Gollasch M, Boschmann M
J Cachexia Sarcopenia Muscle 2023 Dec;14(6):2757-2767. Epub 2023 Oct 27 doi: 10.1002/jcsm.13352. PMID: 37897143Free PMC Article
Predictors of diarrhea, mortality, and weight gain in male dairy calves.
Schinwald M, Creutzinger K, Keunen A, Winder CB, Haley D, Renaud DL
J Dairy Sci 2022 Jun;105(6):5296-5309. Epub 2022 Mar 26 doi: 10.3168/jds.2021-21667. PMID: 35346468
Role of ultrasound in the management of diabetes in pregnancy.
Ahmed B, Abushama M, Khraisheh M, Dudenhausen J
J Matern Fetal Neonatal Med 2015;28(15):1856-63. Epub 2014 Nov 4 doi: 10.3109/14767058.2014.971745. PMID: 25367382
Preconception care: nutritional risks and interventions.
Dean SV, Lassi ZS, Imam AM, Bhutta ZA
Reprod Health 2014 Sep 26;11 Suppl 3(Suppl 3):S3. doi: 10.1186/1742-4755-11-S3-S3. PMID: 25415364Free PMC Article
Care of the infant of the diabetic mother.
Hay WW Jr
Curr Diab Rep 2012 Feb;12(1):4-15. doi: 10.1007/s11892-011-0243-6. PMID: 22094826

Recent systematic reviews

European Association for the Study of Obesity Position Statement on Medical Nutrition Therapy for the Management of Overweight and Obesity in Adults Developed in Collaboration with the European Federation of the Associations of Dietitians.
Hassapidou M, Vlassopoulos A, Kalliostra M, Govers E, Mulrooney H, Ells L, Salas XR, Muscogiuri G, Darleska TH, Busetto L, Yumuk VD, Dicker D, Halford J, Woodward E, Douglas P, Brown J, Brown T
Obes Facts 2023;16(1):11-28. Epub 2022 Dec 15 doi: 10.1159/000528083. PMID: 36521448Free PMC Article
Milk and Dairy Product Consumption and Inflammatory Biomarkers: An Updated Systematic Review of Randomized Clinical Trials.
Ulven SM, Holven KB, Gil A, Rangel-Huerta OD
Adv Nutr 2019 May 1;10(suppl_2):S239-S250. doi: 10.1093/advances/nmy072. PMID: 31089732Free PMC Article
Short and long term health effects of parental tobacco smoking during pregnancy and lactation: a descriptive review.
Banderali G, Martelli A, Landi M, Moretti F, Betti F, Radaelli G, Lassandro C, Verduci E
J Transl Med 2015 Oct 15;13:327. doi: 10.1186/s12967-015-0690-y. PMID: 26472248Free PMC Article
Preconception care: nutritional risks and interventions.
Dean SV, Lassi ZS, Imam AM, Bhutta ZA
Reprod Health 2014 Sep 26;11 Suppl 3(Suppl 3):S3. doi: 10.1186/1742-4755-11-S3-S3. PMID: 25415364Free PMC Article
Swaddling: a systematic review.
van Sleuwen BE, Engelberts AC, Boere-Boonekamp MM, Kuis W, Schulpen TW, L'Hoir MP
Pediatrics 2007 Oct;120(4):e1097-106. doi: 10.1542/peds.2006-2083. PMID: 17908730

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