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Broad ulna

MedGen UID:
892713
•Concept ID:
C4025460
•
Anatomical Abnormality
Synonym: Wide ulna
 
HPO: HP:0003993

Definition

Increased width of the ulna. [from HPO]

Conditions with this feature

Langer mesomelic dysplasia syndrome
MedGen UID:
96585
•Concept ID:
C0432230
•
Disease or Syndrome
Langer mesomelic dysplasia (LMD) is characterized by severe limb aplasia or severe hypoplasia of the ulna and fibula, and a thickened and curved radius and tibia. These changes can result in displacement deformities of the hands and feet. Hypoplasia of the mandible is also observed (Langer, 1967). See also Leri-Weill dyschondrosteosis (127300), a less severe phenotype that results from heterozygous defect in the SHOX or SHOXY genes.
See: Condition Record
Langer mesomelic dysplasia syndrome

Recent clinical studies

Etiology

The simulation of terrible triad injuries in fresh-frozen human cadaveric specimens with intact soft tissue envelope.
Lanzerath F, Knifka J, Leschinger T, Ott N, Kahmann S, Hackl M, Müller LP, Wegmann K
Arch Orthop Trauma Surg 2023 Jul;143(7):4229-4237. Epub 2022 Dec 13 doi: 10.1007/s00402-022-04677-x. PMID: 36512058Free PMC Article
Ulnar diaphyseal stress injuries: a case series.
Dean C, Davis I, Hunt H
Clin Radiol 2022 Jun;77(6):451-457. Epub 2022 Mar 27 doi: 10.1016/j.crad.2022.02.008. PMID: 35354535
Lunate morphology as a risk factor of idiopathic ulnar impaction syndrome.
Park JH, Jang WY, Kwak DH, Park JW
Bone Joint J 2017 Nov;99-B(11):1508-1514. doi: 10.1302/0301-620X.99B11.BJJ-2016-1238.R2. PMID: 29092991
Postcranial morphology and the locomotor habits of living and extinct carnivorans.
Samuels JX, Meachen JA, Sakai SA
J Morphol 2013 Feb;274(2):121-46. Epub 2012 Sep 13 doi: 10.1002/jmor.20077. PMID: 22972188
Intramedullary fixation of forearm fractures.
Rehman S, Sokunbi G
Hand Clin 2010 Aug;26(3):391-401, vii. Epub 2010 Jun 11 doi: 10.1016/j.hcl.2010.04.002. PMID: 20670804

Diagnosis

Fetal hydrops caused by a novel pathogenic MECOM variant.
Wall E, Forsyth J, Kinning E, Marton T
Prenat Diagn 2023 Jun;43(6):717-720. Epub 2023 May 17 doi: 10.1002/pd.6353. PMID: 37160698
Postoperative Imaging of Ulnar Wrist Pain.
Cerezal L, Llopis E, Canga A, Piñal FD
Semin Musculoskelet Radiol 2021 Apr;25(2):329-345. Epub 2021 Aug 9 doi: 10.1055/s-0041-1731331. PMID: 34374067
Lunate morphology as a risk factor of idiopathic ulnar impaction syndrome.
Park JH, Jang WY, Kwak DH, Park JW
Bone Joint J 2017 Nov;99-B(11):1508-1514. doi: 10.1302/0301-620X.99B11.BJJ-2016-1238.R2. PMID: 29092991
A girl with the Weaver syndrome.
Thompson EM, Hill S, Leonard JV, Pembrey ME
J Med Genet 1987 Apr;24(4):232-4. doi: 10.1136/jmg.24.4.232. PMID: 3585940Free PMC Article
Hypochondroplasia.
Newman DE, Dunbar JC
J Can Assoc Radiol 1975 Jun;26(2):95-103. PMID: 1158967

Therapy

Intramedullary fixation of forearm fractures.
Rehman S, Sokunbi G
Hand Clin 2010 Aug;26(3):391-401, vii. Epub 2010 Jun 11 doi: 10.1016/j.hcl.2010.04.002. PMID: 20670804
Methimazole embryopathy: a contribution to defining the phenotype.
Valdez RM, Barbero PM, Liascovich RC, De Rosa LF, Aguirre MA, Alba LG
Reprod Toxicol 2007 Feb;23(2):253-5. Epub 2006 Nov 28 doi: 10.1016/j.reprotox.2006.11.007. PMID: 17218082
Osteomyelitis of the ulna caused by Porphyromonas gingivalis.
Welkerling H, Geissdörfer W, Aigner T, Forst R
J Clin Microbiol 2006 Oct;44(10):3835-7. doi: 10.1128/JCM.00793-06. PMID: 17021123Free PMC Article
Forearm and elbow injury: the influence of rotational position.
McGinley JC, Hopgood BC, Gaughan JP, Sadeghipour K, Kozin SH
J Bone Joint Surg Am 2003 Dec;85(12):2403-9. PMID: 14668511

Prognosis

Falling Down on the Job: Evaluation and Treatment of Fall Risk Among Older Adults With Upper Extremity Fragility Fractures.
McDonough CM, Colla CH, Carmichael D, Tosteson ANA, Tosteson TD, Bell JE, Cantu RV, Lurie JD, Bynum JPW
Phys Ther 2017 Mar 1;97(3):280-289. doi: 10.1093/ptj/pzx009. PMID: 28340130Free PMC Article
Distal radius-ulna fractures in children.
Pannu GS, Herman M
Orthop Clin North Am 2015 Apr;46(2):235-48. Epub 2014 Dec 17 doi: 10.1016/j.ocl.2014.11.003. PMID: 25771318
Traumatic axial dislocation injuries of the wrist.
Reinsmith LE, Garcia-Elias M, Gilula LA
Radiology 2013 Jun;267(3):680-9. doi: 10.1148/radiol.13111682. PMID: 23704291
A model of stress and strain in the interosseous ligament of the forearm based on fiber network theory.
Pfaeffle HJ, Fischer KJ, Srinivasa A, Manson T, Woo SL, Tomaino M
J Biomech Eng 2006 Oct;128(5):725-32. doi: 10.1115/1.2241730. PMID: 16995759
A centralization procedure for radial clubhand.
Watson HK, Beebe RD, Cruz NI
J Hand Surg Am 1984 Jul;9(4):541-7. doi: 10.1016/s0363-5023(84)80107-0. PMID: 6747239

Clinical prediction guides

Topographical Anatomy of the Distal Ulna Attachment of the Radioulnar Ligament.
Shin WJ, Kim JP, Yang HM, Lee EY, Go JH, Heo K
J Hand Surg Am 2017 Jul;42(7):517-524. Epub 2017 Apr 25 doi: 10.1016/j.jhsa.2017.03.031. PMID: 28450099
Falling Down on the Job: Evaluation and Treatment of Fall Risk Among Older Adults With Upper Extremity Fragility Fractures.
McDonough CM, Colla CH, Carmichael D, Tosteson ANA, Tosteson TD, Bell JE, Cantu RV, Lurie JD, Bynum JPW
Phys Ther 2017 Mar 1;97(3):280-289. doi: 10.1093/ptj/pzx009. PMID: 28340130Free PMC Article
Forearm articular proportions and the antebrachial index in Homo sapiens, Australopithecus afarensis and the great apes.
Williams FL, Cunningham DL, Amaral LQ
Homo 2015 Dec;66(6):477-91. Epub 2015 Jul 17 doi: 10.1016/j.jchb.2015.07.001. PMID: 26256651
Traumatic axial dislocation injuries of the wrist.
Reinsmith LE, Garcia-Elias M, Gilula LA
Radiology 2013 Jun;267(3):680-9. doi: 10.1148/radiol.13111682. PMID: 23704291
A model of stress and strain in the interosseous ligament of the forearm based on fiber network theory.
Pfaeffle HJ, Fischer KJ, Srinivasa A, Manson T, Woo SL, Tomaino M
J Biomech Eng 2006 Oct;128(5):725-32. doi: 10.1115/1.2241730. PMID: 16995759

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