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Jejunal adenocarcinoma

MedGen UID:
893029
•Concept ID:
C4072935
•
Neoplastic Process
Synonyms: Jejunal Adenocarcinoma; jejunal adenocarcinoma; jejunal adenocarcinoma (disease); jejunum adenocarcinoma
 
HPO: HP:0030411
Monarch Initiative: MONDO:0000541

Definition

A malignant epithelial tumor with a glandular organization that originates in the jejunum. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVJejunal adenocarcinoma

Professional guidelines

PubMed

Small bowel polyps and tumours: endoscopic detection and treatment by double-balloon enteroscopy.
Fry LC, Neumann H, Kuester D, Kuhn R, Bellutti M, Malfertheiner P, Monkemuller K
Aliment Pharmacol Ther 2009 Jan;29(1):135-42. Epub 2008 Oct 3 doi: 10.1111/j.1365-2036.2008.03864.x. PMID: 18945259

Recent clinical studies

Etiology

Small Bowel Adenocarcinoma: a Nationwide Population-Based Study.
Mohammed A, Trujillo S, Ghoneim S, Paranji N, Waghray N
J Gastrointest Cancer 2023 Mar;54(1):67-72. Epub 2022 Jan 10 doi: 10.1007/s12029-021-00653-7. PMID: 35001295
Gastric metastasis from small bowel adenocarcinoma in a Lynch syndrome patient.
Matsumoto A, Shimada Y, Kondo S, Mizuno KI, Nakano M, Yamai D, Nakano M, Nyuzuki H, Umezu H, Wakai T
Clin J Gastroenterol 2022 Jun;15(3):575-581. Epub 2022 Mar 28 doi: 10.1007/s12328-022-01625-5. PMID: 35347646
Effectiveness of a surveillance program of upper endoscopy for upper gastrointestinal cancers in Lynch syndrome patients.
Ceravolo AH, Yang JJ, Latham A, Markowitz AJ, Shia J, Mermelstein J, Calo D, Gerdes H, Ludwig E, Schattner MA, Stadler ZK, Kantor E, Du M, Mendelsohn RB
Int J Colorectal Dis 2022 Jan;37(1):231-238. Epub 2021 Oct 26 doi: 10.1007/s00384-021-04053-y. PMID: 34698909Free PMC Article
Intestinal dehiscence and mortality in cats undergoing gastrointestinal surgery.
Hiebert EC, Barry SL, Sawyere DM, DeMonaco SM, Muro NM
J Feline Med Surg 2022 Aug;24(8):779-786. Epub 2021 Oct 19 doi: 10.1177/1098612X211048454. PMID: 34663127
Vascular endothelial growth factor-A is an Immunohistochemical biomarker for the efficacy of bevacizumab-containing chemotherapy for duodenal and jejunal adenocarcinoma.
Amano T, Iijima H, Shinzaki S, Tashiro T, Iwatani S, Tani M, Otake Y, Yoshihara T, Sugimoto A, Egawa S, Yamaguchi S, Kinoshita K, Araki M, Hirao M, Sakakibara Y, Hiyama S, Ogawa H, Nagaike K, Murata J, Komori M, Okuda Y, Kizu T, Tsujii Y, Hayashi Y, Inoue T, Takahashi H, Mizushima T, Morii E, Takehara T
BMC Cancer 2021 Aug 31;21(1):978. doi: 10.1186/s12885-021-08724-5. PMID: 34465291Free PMC Article

Diagnosis

Small Bowel Adenocarcinoma: a Nationwide Population-Based Study.
Mohammed A, Trujillo S, Ghoneim S, Paranji N, Waghray N
J Gastrointest Cancer 2023 Mar;54(1):67-72. Epub 2022 Jan 10 doi: 10.1007/s12029-021-00653-7. PMID: 35001295
Jejunal adenocarcinoma after biliopancreatic diversion. Report of a case.
Cossu ML, Fancellu A, Feo CF, Ginesu GC, Sogos S, Ariu ML, Porcu A
Obes Res Clin Pract 2022 May-Jun;16(3):269-271. Epub 2022 May 11 doi: 10.1016/j.orcp.2022.05.002. PMID: 35562313
Intestinal dehiscence and mortality in cats undergoing gastrointestinal surgery.
Hiebert EC, Barry SL, Sawyere DM, DeMonaco SM, Muro NM
J Feline Med Surg 2022 Aug;24(8):779-786. Epub 2021 Oct 19 doi: 10.1177/1098612X211048454. PMID: 34663127
A Challenging Diagnosis of Jejunal Adenocarcinoma in a Celiac Patient: Case Report and Systematic Review of the Literature.
Zullo A, De Francesco V, Manta R, Ridola L, Lorenzetti R
J Gastrointestin Liver Dis 2017 Dec;26(4):411-415. doi: 10.15403/jgld.2014.1121.264.zet. PMID: 29253057
Jejunal adenocarcinoma: still an elusive diagnosis. Case report and review of the literature.
Iusco DR, Altilia F, Massa ST, Schirone S, Villani P, Roggia G
Chir Ital 2008 May-Jun;60(3):457-62. PMID: 18709788

Therapy

Jejunal adenocarcinoma after biliopancreatic diversion. Report of a case.
Cossu ML, Fancellu A, Feo CF, Ginesu GC, Sogos S, Ariu ML, Porcu A
Obes Res Clin Pract 2022 May-Jun;16(3):269-271. Epub 2022 May 11 doi: 10.1016/j.orcp.2022.05.002. PMID: 35562313
First reported case of Robinsoniella peoriensis pyometra and bloodstream infection: A case report and review of the literature.
Mejia-Gomez J, Zigras T, Patel Y, Wolfman W, Philippopoulos E, Shaltout N, Rotstein C, Laframboise S, Patel SN, Kus JV, Poutanen SM, Hosseini-Moghaddam SM
Anaerobe 2022 Jun;75:102581. Epub 2022 May 6 doi: 10.1016/j.anaerobe.2022.102581. PMID: 35526662
Intestinal dehiscence and mortality in cats undergoing gastrointestinal surgery.
Hiebert EC, Barry SL, Sawyere DM, DeMonaco SM, Muro NM
J Feline Med Surg 2022 Aug;24(8):779-786. Epub 2021 Oct 19 doi: 10.1177/1098612X211048454. PMID: 34663127
Vascular endothelial growth factor-A is an Immunohistochemical biomarker for the efficacy of bevacizumab-containing chemotherapy for duodenal and jejunal adenocarcinoma.
Amano T, Iijima H, Shinzaki S, Tashiro T, Iwatani S, Tani M, Otake Y, Yoshihara T, Sugimoto A, Egawa S, Yamaguchi S, Kinoshita K, Araki M, Hirao M, Sakakibara Y, Hiyama S, Ogawa H, Nagaike K, Murata J, Komori M, Okuda Y, Kizu T, Tsujii Y, Hayashi Y, Inoue T, Takahashi H, Mizushima T, Morii E, Takehara T
BMC Cancer 2021 Aug 31;21(1):978. doi: 10.1186/s12885-021-08724-5. PMID: 34465291Free PMC Article
A case of adenocarcinoma developed in the small intestine with chronic strongyloidiasis.
Ishikawa S, Maeda T, Hattori K, Watanabe T, Kuramoto T, Ueno S, Ueno G, Yamada T, Kanazawa A, Sakaguchi M, Tsukamoto Y
Clin J Gastroenterol 2017 Dec;10(6):519-523. Epub 2017 Oct 7 doi: 10.1007/s12328-017-0783-7. PMID: 28988405

Prognosis

Vascular endothelial growth factor-A is an Immunohistochemical biomarker for the efficacy of bevacizumab-containing chemotherapy for duodenal and jejunal adenocarcinoma.
Amano T, Iijima H, Shinzaki S, Tashiro T, Iwatani S, Tani M, Otake Y, Yoshihara T, Sugimoto A, Egawa S, Yamaguchi S, Kinoshita K, Araki M, Hirao M, Sakakibara Y, Hiyama S, Ogawa H, Nagaike K, Murata J, Komori M, Okuda Y, Kizu T, Tsujii Y, Hayashi Y, Inoue T, Takahashi H, Mizushima T, Morii E, Takehara T
BMC Cancer 2021 Aug 31;21(1):978. doi: 10.1186/s12885-021-08724-5. PMID: 34465291Free PMC Article
Metastatic Ovarian Tumors Originating From a Small Bowel Adenocarcinoma - A Case Report and Brief Literature Review.
Mitsushita J, Netsu S, Suzuki K, Nokubi M, Tanaka A
Int J Gynecol Pathol 2017 May;36(3):253-260. doi: 10.1097/PGP.0000000000000314. PMID: 27513076
Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma--therapeutic implications.
Cienfuegos JA, Baixauli J, Zozaya G, Bueno A, Arredondo J, Regueira FM, Angós R, Hernández-Lizoáin JL, Idoate MA
Rev Esp Enferm Dig 2009 Dec;101(12):875-9. doi: 10.4321/s1130-01082009001200009. PMID: 20082550
Complications and follow-up after pancreas-preserving total duodenectomy for duodenal polyps.
Al-Sarireh B, Ghaneh P, Gardner-Thorpe J, Raraty M, Hartley M, Sutton R, Neoptolemos JP
Br J Surg 2008 Dec;95(12):1506-11. doi: 10.1002/bjs.6412. PMID: 18991295
Primary jejunal adenocarcinoma masquerading as a primary ovarian malignancy.
Tsuruchi N, Kubota H, Tsukamoto N, Kurano A
Gynecol Oncol 1995 Jul;58(1):129-32. doi: 10.1006/gyno.1995.1196. PMID: 7789880

Clinical prediction guides

Vascular endothelial growth factor-A is an Immunohistochemical biomarker for the efficacy of bevacizumab-containing chemotherapy for duodenal and jejunal adenocarcinoma.
Amano T, Iijima H, Shinzaki S, Tashiro T, Iwatani S, Tani M, Otake Y, Yoshihara T, Sugimoto A, Egawa S, Yamaguchi S, Kinoshita K, Araki M, Hirao M, Sakakibara Y, Hiyama S, Ogawa H, Nagaike K, Murata J, Komori M, Okuda Y, Kizu T, Tsujii Y, Hayashi Y, Inoue T, Takahashi H, Mizushima T, Morii E, Takehara T
BMC Cancer 2021 Aug 31;21(1):978. doi: 10.1186/s12885-021-08724-5. PMID: 34465291Free PMC Article
Metastatic Ovarian Tumors Originating From a Small Bowel Adenocarcinoma - A Case Report and Brief Literature Review.
Mitsushita J, Netsu S, Suzuki K, Nokubi M, Tanaka A
Int J Gynecol Pathol 2017 May;36(3):253-260. doi: 10.1097/PGP.0000000000000314. PMID: 27513076
Oxaliplatin/5-fluorouracil/leucovorin (FOLFOX4) regimen as an adjuvant chemotherapy in the treatment of advanced jejunal adenocarcinoma: a report of 2 cases.
Chen CW, Wang WM, Su YC, Wu JY, Hsieh JS, Wang JY
Med Princ Pract 2008;17(6):496-9. Epub 2008 Oct 3 doi: 10.1159/000151574. PMID: 18836281
Malignant tumours of the small intestine: a case of jejunal adenocarcinoma.
Forte A, Gallinaro LS, Bertagni A, Prece V, Montesano G, Nasti AG, Palumbo P
Eur Rev Med Pharmacol Sci 1999 Jan-Feb;3(1):23-6. PMID: 10710826
The sonographic appearances of small bowel tumours.
Bin W, Jianguo L, Baowei D
Clin Radiol 1992 Jul;46(1):30-3. doi: 10.1016/s0009-9260(05)80030-3. PMID: 1643779

Recent systematic reviews

A Challenging Diagnosis of Jejunal Adenocarcinoma in a Celiac Patient: Case Report and Systematic Review of the Literature.
Zullo A, De Francesco V, Manta R, Ridola L, Lorenzetti R
J Gastrointestin Liver Dis 2017 Dec;26(4):411-415. doi: 10.15403/jgld.2014.1121.264.zet. PMID: 29253057

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