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Sudden loss of visual acuity

MedGen UID:
893113
•Concept ID:
C4072828
•
Finding
Synonyms: Sudden central visual loss; Sudden decrease in vision
 
HPO: HP:0001117

Definition

Severe loss of visual acuity within hours or days. This is characteristic of Leber hereditary optic neuropathy. [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVSudden loss of visual acuity

Professional guidelines

PubMed

Optic neuritis in pediatric population: a review in current tendencies of diagnosis and management.
Pérez-Cambrodí RJ, Gómez-Hurtado Cubillana A, Merino-Suárez ML, Piñero-Llorens DP, Laria-Ochaita C
J Optom 2014 Jul-Sep;7(3):125-30. Epub 2014 Feb 18 doi: 10.1016/j.optom.2013.12.008. PMID: 25000867Free PMC Article

Recent clinical studies

Etiology

Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children: A Multicenter Randomized Controlled Trial.
Jiang Y, Zhu Z, Tan X, Kong X, Zhong H, Zhang J, Xiong R, Yuan Y, Zeng J, Morgan IG, He M
Ophthalmology 2022 May;129(5):509-519. Epub 2021 Dec 1 doi: 10.1016/j.ophtha.2021.11.023. PMID: 34863776
Pediatric vitreous hemorrhage: A narrative review.
Naik AU, Rishi E, Rishi P
Indian J Ophthalmol 2019 Jun;67(6):732-739. doi: 10.4103/ijo.IJO_688_18. PMID: 31124481Free PMC Article
Disorders of the inner-ear balance organs and their pathways.
Young AS, Rosengren SM, Welgampola MS
Handb Clin Neurol 2018;159:385-401. doi: 10.1016/B978-0-444-63916-5.00025-2. PMID: 30482329
Hemorrhagic unilateral retinopathy.
Kon Graversen VA, Jampol LM, Meredith T, Landers M 3rd, Slakter J, Brucker AJ, Rabb M
Retina 2014 Mar;34(3):483-9. doi: 10.1097/IAE.0b013e3182a48759. PMID: 24096883
Retinal arterial macroaneurysms.
Pitkänen L, Tommila P, Kaarniranta K, Jääskeläinen JE, Kinnunen K
Acta Ophthalmol 2014 Mar;92(2):101-4. Epub 2013 Jun 25 doi: 10.1111/aos.12210. PMID: 23800325

Diagnosis

Autosomal recessive Leber hereditary optic neuropathy, a new neuro-ophthalmo-genetic paradigm.
Lenaers G, Beaulieu C, Charif M, Gerber S, Kaplan J, Rozet JM
Brain 2023 Aug 1;146(8):3156-3161. doi: 10.1093/brain/awad131. PMID: 37071596Free PMC Article
Pediatric vitreous hemorrhage: A narrative review.
Naik AU, Rishi E, Rishi P
Indian J Ophthalmol 2019 Jun;67(6):732-739. doi: 10.4103/ijo.IJO_688_18. PMID: 31124481Free PMC Article
Hemorrhagic unilateral retinopathy.
Kon Graversen VA, Jampol LM, Meredith T, Landers M 3rd, Slakter J, Brucker AJ, Rabb M
Retina 2014 Mar;34(3):483-9. doi: 10.1097/IAE.0b013e3182a48759. PMID: 24096883
Retinal arterial macroaneurysms.
Pitkänen L, Tommila P, Kaarniranta K, Jääskeläinen JE, Kinnunen K
Acta Ophthalmol 2014 Mar;92(2):101-4. Epub 2013 Jun 25 doi: 10.1111/aos.12210. PMID: 23800325
Ischemic optic neuropathy.
Fontal MR, Kerrison JB, Garcia R, Oria V
Semin Neurol 2007 Jul;27(3):221-32. doi: 10.1055/s-2007-979686. PMID: 17577864

Therapy

Interventions for acute non-arteritic central retinal artery occlusion.
Lin JC, Song S, Ng SM, Scott IU, Greenberg PB
Cochrane Database Syst Rev 2023 Jan 30;1(1):CD001989. doi: 10.1002/14651858.CD001989.pub3. PMID: 36715340Free PMC Article
Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children: A Multicenter Randomized Controlled Trial.
Jiang Y, Zhu Z, Tan X, Kong X, Zhong H, Zhang J, Xiong R, Yuan Y, Zeng J, Morgan IG, He M
Ophthalmology 2022 May;129(5):509-519. Epub 2021 Dec 1 doi: 10.1016/j.ophtha.2021.11.023. PMID: 34863776
Infliximab-induced optic neuritis.
Dermawan A, So K, Venugopal K, Picardo S
BMJ Case Rep 2020 Dec 22;13(12) doi: 10.1136/bcr-2020-236041. PMID: 33370961Free PMC Article
Myopic Choroidal Neovascularization: Review, Guidance, and Consensus Statement on Management.
Cheung CMG, Arnold JJ, Holz FG, Park KH, Lai TYY, Larsen M, Mitchell P, Ohno-Matsui K, Chen SJ, Wolf S, Wong TY
Ophthalmology 2017 Nov;124(11):1690-1711. Epub 2017 Jun 24 doi: 10.1016/j.ophtha.2017.04.028. PMID: 28655539
Wet age related macular degeneration management and follow-up.
Alexandru MR, Alexandra NM
Rom J Ophthalmol 2016 Jan-Mar;60(1):9-13. PMID: 27220225Free PMC Article

Prognosis

Dissociative Visual Loss in Children and Adolescents.
Brunner R, Jägle H, Kandsperger S
Klin Monbl Augenheilkd 2021 Oct;238(10):1084-1091. Epub 2021 Oct 18 doi: 10.1055/a-1617-3193. PMID: 34662923
Myopic Choroidal Neovascularization: Review, Guidance, and Consensus Statement on Management.
Cheung CMG, Arnold JJ, Holz FG, Park KH, Lai TYY, Larsen M, Mitchell P, Ohno-Matsui K, Chen SJ, Wolf S, Wong TY
Ophthalmology 2017 Nov;124(11):1690-1711. Epub 2017 Jun 24 doi: 10.1016/j.ophtha.2017.04.028. PMID: 28655539
Wet age related macular degeneration management and follow-up.
Alexandru MR, Alexandra NM
Rom J Ophthalmol 2016 Jan-Mar;60(1):9-13. PMID: 27220225Free PMC Article
Ocular ischemic syndrome.
Chen KJ, Chen SN, Kao LY, Ho CL, Chen TL, Lai CC, Wu SC
Chang Gung Med J 2001 Aug;24(8):483-91. PMID: 11601190
Ocular ischemic syndrome.
Mizener JB, Podhajsky P, Hayreh SS
Ophthalmology 1997 May;104(5):859-64. doi: 10.1016/s0161-6420(97)30221-8. PMID: 9160035

Clinical prediction guides

Interventions for acute non-arteritic central retinal artery occlusion.
Lin JC, Song S, Ng SM, Scott IU, Greenberg PB
Cochrane Database Syst Rev 2023 Jan 30;1(1):CD001989. doi: 10.1002/14651858.CD001989.pub3. PMID: 36715340Free PMC Article
Grading for suction loss in small incision lenticule extraction.
Huang Q, Liu L, Ma P, Sun Y, Wang Z, Bai J, Liu T
Int Ophthalmol 2023 Feb;43(2):665-675. Epub 2022 Aug 31 doi: 10.1007/s10792-022-02456-6. PMID: 36044110
Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children: A Multicenter Randomized Controlled Trial.
Jiang Y, Zhu Z, Tan X, Kong X, Zhong H, Zhang J, Xiong R, Yuan Y, Zeng J, Morgan IG, He M
Ophthalmology 2022 May;129(5):509-519. Epub 2021 Dec 1 doi: 10.1016/j.ophtha.2021.11.023. PMID: 34863776
Pediatric vitreous hemorrhage: A narrative review.
Naik AU, Rishi E, Rishi P
Indian J Ophthalmol 2019 Jun;67(6):732-739. doi: 10.4103/ijo.IJO_688_18. PMID: 31124481Free PMC Article
Wet age related macular degeneration management and follow-up.
Alexandru MR, Alexandra NM
Rom J Ophthalmol 2016 Jan-Mar;60(1):9-13. PMID: 27220225Free PMC Article

Recent systematic reviews

Interventions for acute non-arteritic central retinal artery occlusion.
Lin JC, Song S, Ng SM, Scott IU, Greenberg PB
Cochrane Database Syst Rev 2023 Jan 30;1(1):CD001989. doi: 10.1002/14651858.CD001989.pub3. PMID: 36715340Free PMC Article
Surgery for nonarteritic anterior ischemic optic neuropathy.
Dickersin K, Li T
Cochrane Database Syst Rev 2015 Mar 12;2015(3):CD001538. doi: 10.1002/14651858.CD001538.pub4. PMID: 25763979Free PMC Article
Surgery for nonarteritic anterior ischemic optic neuropathy.
Dickersin K, Manheimer E, Li T
Cochrane Database Syst Rev 2012 Jan 18;1:CD001538. doi: 10.1002/14651858.CD001538.pub3. PMID: 22258945Free PMC Article
Surgery for nonarteritic anterior ischemic optic neuropathy.
Dickersin K, Manheimer E, Li T
Cochrane Database Syst Rev 2006 Jan 25;(1):CD001538. doi: 10.1002/14651858.CD001538.pub2. PMID: 16437435
Surgery for nonarteritic anterior ischemic optic neuropathy.
Dickersin K, Manheimer E
Cochrane Database Syst Rev 2000;(2):CD001538. doi: 10.1002/14651858.CD001538. PMID: 10796806

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