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Increased proportion of memory B cells

MedGen UID:
893115
Concept ID:
C4072914
Finding
Synonym: Increased memory B cell count
 
HPO: HP:0030375

Definition

An elevation in the proportion of memory B cells (CD19+/CD27+) in circulation relative to the total number of B cells. Memory B cells develop from naive B cells. Upon antigen rechallenge, memory B cells rapidly expand and differentiate into plasma cells under the cognate control of memory Th cells (Phase IV). [from HPO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased proportion of memory B cells

Professional guidelines

PubMed

Ruschil C, Gabernet G, Kemmerer CL, Jarboui MA, Klose F, Poli S, Ziemann U, Nahnsen S, Kowarik MC
Front Immunol 2023;14:1133967. Epub 2023 Mar 7 doi: 10.3389/fimmu.2023.1133967. PMID: 36960053Free PMC Article
McKenzie CI, Varese N, Aui PM, Reinwald S, Wines BD, Hogarth PM, Thien F, Hew M, Rolland JM, O'Hehir RE, van Zelm MC
Allergy 2023 Mar;78(3):822-835. Epub 2022 Oct 1 doi: 10.1111/all.15529. PMID: 36153670Free PMC Article
Jiao L, Xiang Y, Li S, Zhang F, Ruan X, Guo S
J Neuroimmunol 2020 Aug 15;345:577280. Epub 2020 Jun 5 doi: 10.1016/j.jneuroim.2020.577280. PMID: 32563125

Recent clinical studies

Etiology

Adjei JK, Aniagyei W, Adankwah E, Seyfarth J, Mayatepek E, Berko DA, Ackam N, Annani-Akollor ME, Sakyi SA, Amoako YA, Owusu D, Jacobsen M, Phillips RO
BMC Infect Dis 2023 Jun 12;23(1):393. doi: 10.1186/s12879-023-08370-1. PMID: 37308884Free PMC Article
Kopitar AN, Repas J, Janžič L, Bizjak M, Vesel TT, Emeršič N, Avramovič MZ, Ihan A, Avčin T, Pavlin M
Front Immunol 2023;14:1157702. Epub 2023 Apr 20 doi: 10.3389/fimmu.2023.1157702. PMID: 37153551Free PMC Article
Forestier A, Guerrier T, Jouvray M, Giovannelli J, Lefèvre G, Sobanski V, Hauspie C, Hachulla E, Hatron PY, Zéphir H, Vermersch P, Labalette M, Launay D, Dubucquoi S
Autoimmun Rev 2018 Mar;17(3):244-255. Epub 2018 Jan 16 doi: 10.1016/j.autrev.2017.10.015. PMID: 29343447
Carvajal Alegria G, Gazeau P, Hillion S, Daïen CI, Cornec DYK
Clin Rev Allergy Immunol 2017 Oct;53(2):219-236. doi: 10.1007/s12016-017-8608-5. PMID: 28474288
Simonin L, Pasquier E, Leroyer C, Cornec D, Lemerle J, Bendaoud B, Hillion S, Pers JO, Couturaud F, Renaudineau Y
Clin Rev Allergy Immunol 2017 Aug;53(1):14-27. doi: 10.1007/s12016-016-8568-1. PMID: 27342459

Diagnosis

McKenzie CI, Varese N, Aui PM, Reinwald S, Wines BD, Hogarth PM, Thien F, Hew M, Rolland JM, O'Hehir RE, van Zelm MC
Allergy 2023 Mar;78(3):822-835. Epub 2022 Oct 1 doi: 10.1111/all.15529. PMID: 36153670Free PMC Article
Zheng PF, Zou QC, Chen LZ, Liu P, Liu ZY, Pan HW
J Transl Med 2022 Jul 21;20(1):321. doi: 10.1186/s12967-022-03517-1. PMID: 35864510Free PMC Article
Peng L, Jin X, Li BY, Zeng X, Liao BH, Jin T, Chen JW, Gao XS, Wang W, He Q, Chen G, Gong LN, Shen H, Wang KJ, Li H, Luo DY
Signal Transduct Target Ther 2022 May 20;7(1):161. doi: 10.1038/s41392-022-00962-8. PMID: 35589692Free PMC Article
Carvajal Alegria G, Gazeau P, Hillion S, Daïen CI, Cornec DYK
Clin Rev Allergy Immunol 2017 Oct;53(2):219-236. doi: 10.1007/s12016-017-8608-5. PMID: 28474288
Simonin L, Pasquier E, Leroyer C, Cornec D, Lemerle J, Bendaoud B, Hillion S, Pers JO, Couturaud F, Renaudineau Y
Clin Rev Allergy Immunol 2017 Aug;53(1):14-27. doi: 10.1007/s12016-016-8568-1. PMID: 27342459

Therapy

Raqib R, Akhtar E, Ahsanul Haq M, Ahmed S, Haque F, Chowdhury MAH, Shahriar MH, Begum BA, Eunus M, Sarwar G, Parvez F, Sharker Y, Ahsan H, Yunus M
Environ Int 2023 Sep;179:108137. Epub 2023 Aug 9 doi: 10.1016/j.envint.2023.108137. PMID: 37579572
Ruschil C, Gabernet G, Kemmerer CL, Jarboui MA, Klose F, Poli S, Ziemann U, Nahnsen S, Kowarik MC
Front Immunol 2023;14:1133967. Epub 2023 Mar 7 doi: 10.3389/fimmu.2023.1133967. PMID: 36960053Free PMC Article
Peng B, Hu Q, He R, Hou H, Lian D, Chen Y, Li H, Song L, Gao Y, Chen T, Zhang G, Li J
BMC Complement Med Ther 2023 Feb 21;23(1):62. doi: 10.1186/s12906-023-03885-1. PMID: 36810081Free PMC Article
Wang W, Liu L, Hui X, Wang Y, Ying W, Zhou Q, Hou J, Yang M, Sun B, Sun J, Wang X
BMC Immunol 2021 Mar 17;22(1):19. doi: 10.1186/s12865-021-00411-1. PMID: 33731004Free PMC Article
Xiong Y, Cheng S, Wu X, Ren Y, Xie X
BMC Immunol 2019 Jul 8;20(1):24. doi: 10.1186/s12865-019-0301-4. PMID: 31286875Free PMC Article

Prognosis

Kopitar AN, Repas J, Janžič L, Bizjak M, Vesel TT, Emeršič N, Avramovič MZ, Ihan A, Avčin T, Pavlin M
Front Immunol 2023;14:1157702. Epub 2023 Apr 20 doi: 10.3389/fimmu.2023.1157702. PMID: 37153551Free PMC Article
Scharf L, Axelsson H, Emmanouilidi A, Mathew NR, Sheward DJ, Leach S, Isakson P, Smirnov IV, Marklund E, Miron N, Andersson LM, Gisslén M, Murrell B, Lundgren A, Bemark M, Angeletti D
JCI Insight 2023 Jan 10;8(1) doi: 10.1172/jci.insight.165299. PMID: 36445762Free PMC Article
McKenzie CI, Varese N, Aui PM, Reinwald S, Wines BD, Hogarth PM, Thien F, Hew M, Rolland JM, O'Hehir RE, van Zelm MC
Allergy 2023 Mar;78(3):822-835. Epub 2022 Oct 1 doi: 10.1111/all.15529. PMID: 36153670Free PMC Article
Emsen A, Uçaryılmaz H, Güler T, Artaç H
Turk J Pediatr 2022;64(2):228-238. doi: 10.24953/turkjped.2021.83. PMID: 35611411
Carvajal Alegria G, Gazeau P, Hillion S, Daïen CI, Cornec DYK
Clin Rev Allergy Immunol 2017 Oct;53(2):219-236. doi: 10.1007/s12016-017-8608-5. PMID: 28474288

Clinical prediction guides

Shimojima Y, Kishida D, Ichikawa T, Takamatsu R, Nomura S, Sekijima Y
Clin Exp Immunol 2023 Jul 5;213(1):125-137. doi: 10.1093/cei/uxad024. PMID: 36794867Free PMC Article
Kondo Y, Abe S, Toko H, Hirota T, Takahashi H, Shimizu M, Noma H, Tsuboi H, Matsumoto I, Inaba T, Sumida T
Sci Rep 2023 Jan 24;13(1):1304. doi: 10.1038/s41598-022-27153-3. PMID: 36693893Free PMC Article
Scharf L, Axelsson H, Emmanouilidi A, Mathew NR, Sheward DJ, Leach S, Isakson P, Smirnov IV, Marklund E, Miron N, Andersson LM, Gisslén M, Murrell B, Lundgren A, Bemark M, Angeletti D
JCI Insight 2023 Jan 10;8(1) doi: 10.1172/jci.insight.165299. PMID: 36445762Free PMC Article
Emsen A, Uçaryılmaz H, Güler T, Artaç H
Turk J Pediatr 2022;64(2):228-238. doi: 10.24953/turkjped.2021.83. PMID: 35611411
Forestier A, Guerrier T, Jouvray M, Giovannelli J, Lefèvre G, Sobanski V, Hauspie C, Hachulla E, Hatron PY, Zéphir H, Vermersch P, Labalette M, Launay D, Dubucquoi S
Autoimmun Rev 2018 Mar;17(3):244-255. Epub 2018 Jan 16 doi: 10.1016/j.autrev.2017.10.015. PMID: 29343447

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