U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Visual acuity test abnormality

MedGen UID:
893125
•Concept ID:
C4073006
•
Finding
HPO: HP:0030532

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVVisual acuity test abnormality

Professional guidelines

PubMed

The role of visual electrodiagnostics in management of children with neurofibromatosis type 1.
Tekavčič Pompe M, Pečarič Meglič N, Šuštar Habjan M
Doc Ophthalmol 2023 Apr;146(2):121-136. Epub 2023 Jan 18 doi: 10.1007/s10633-023-09920-3. PMID: 36652041
Genotype and Long-term Clinical Course of Bietti Crystalline Dystrophy in Korean and Japanese Patients.
Murakami Y, Koyanagi Y, Fukushima M, Yoshimura M, Fujiwara K, Akiyama M, Momozawa Y, Ueno S, Terasaki H, Oishi A, Miyata M, Ikeda H, Tsujikawa A, Mizobuchi K, Hayashi T, Fujinami K, Tsunoda K, Park JY, Han J, Kim M, Lee CS, Kim SJ, Park TK, Joo K, Woo SJ, Ikeda Y, Sonoda KH
Ophthalmol Retina 2021 Dec;5(12):1269-1279. Epub 2021 Feb 23 doi: 10.1016/j.oret.2021.02.009. PMID: 33636399
Bilateral vestibulopathy: Diagnostic criteria Consensus document of the Classification Committee of the Bárány Society.
Strupp M, Kim JS, Murofushi T, Straumann D, Jen JC, Rosengren SM, Della Santina CC, Kingma H
J Vestib Res 2017;27(4):177-189. doi: 10.3233/VES-170619. PMID: 29081426Free PMC Article

Recent clinical studies

Etiology

Oral Hypoxia-Inducible Factor 2α Inhibitor Belzutifan in Ocular von Hippel-Lindau Disease: Subgroup Analysis of the Single-Arm Phase 2 LITESPARK-004 Study.
Wiley HE, Srinivasan R, Maranchie JK, Chhablani J, Iversen ABB, Kruse A, Jonasch E, Gombos DS, Else T, Demirci H, Maughan BL, Hartnett ME, Coleman HR, Fu W, Perini RF, Liu Y, Linehan WM, Chew EY; LITESPARK-004 Investigator Group - Ocular VHL
Ophthalmology 2024 Nov;131(11):1324-1332. Epub 2024 Jun 6 doi: 10.1016/j.ophtha.2024.05.024. PMID: 38849055
Scleral tunnel phacoemulsification: Approach for eyes with severe microcornea.
Khokhar S, Gupta S, Tewari R, Agarwal R, Gogia V, Sinha G, Agarwal T
Indian J Ophthalmol 2016 Apr;64(4):320-2. doi: 10.4103/0301-4738.182949. PMID: 27221687Free PMC Article
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.
Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO
Arch Ophthalmol 2002 Jun;120(6):701-13; discussion 829-30. doi: 10.1001/archopht.120.6.701. PMID: 12049574
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Age-Related Eye Disease Study Research Group
Arch Ophthalmol 2001 Oct;119(10):1417-36. doi: 10.1001/archopht.119.10.1417. PMID: 11594942Free PMC Article
Goniosurgery for prevention of aniridic glaucoma.
Chen TC, Walton DS
Arch Ophthalmol 1999 Sep;117(9):1144-8. doi: 10.1001/archopht.117.9.1144. PMID: 10496385

Diagnosis

Oral Hypoxia-Inducible Factor 2α Inhibitor Belzutifan in Ocular von Hippel-Lindau Disease: Subgroup Analysis of the Single-Arm Phase 2 LITESPARK-004 Study.
Wiley HE, Srinivasan R, Maranchie JK, Chhablani J, Iversen ABB, Kruse A, Jonasch E, Gombos DS, Else T, Demirci H, Maughan BL, Hartnett ME, Coleman HR, Fu W, Perini RF, Liu Y, Linehan WM, Chew EY; LITESPARK-004 Investigator Group - Ocular VHL
Ophthalmology 2024 Nov;131(11):1324-1332. Epub 2024 Jun 6 doi: 10.1016/j.ophtha.2024.05.024. PMID: 38849055
Scleral tunnel phacoemulsification: Approach for eyes with severe microcornea.
Khokhar S, Gupta S, Tewari R, Agarwal R, Gogia V, Sinha G, Agarwal T
Indian J Ophthalmol 2016 Apr;64(4):320-2. doi: 10.4103/0301-4738.182949. PMID: 27221687Free PMC Article
Macular dystrophy in Heimler syndrome.
Lima LH, Barbazetto IA, Chen R, Yannuzzi LA, Tsang SH, Spaide RF
Ophthalmic Genet 2011 Jun;32(2):97-100. Epub 2011 Mar 2 doi: 10.3109/13816810.2010.551797. PMID: 21366429Free PMC Article
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.
Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO
Arch Ophthalmol 2002 Jun;120(6):701-13; discussion 829-30. doi: 10.1001/archopht.120.6.701. PMID: 12049574
Blue cone monochromatism.
Weiss AH, Biersdorf WR
J Pediatr Ophthalmol Strabismus 1989 Sep-Oct;26(5):218-23. doi: 10.3928/0191-3913-19890901-04. PMID: 2795409

Therapy

Oral Hypoxia-Inducible Factor 2α Inhibitor Belzutifan in Ocular von Hippel-Lindau Disease: Subgroup Analysis of the Single-Arm Phase 2 LITESPARK-004 Study.
Wiley HE, Srinivasan R, Maranchie JK, Chhablani J, Iversen ABB, Kruse A, Jonasch E, Gombos DS, Else T, Demirci H, Maughan BL, Hartnett ME, Coleman HR, Fu W, Perini RF, Liu Y, Linehan WM, Chew EY; LITESPARK-004 Investigator Group - Ocular VHL
Ophthalmology 2024 Nov;131(11):1324-1332. Epub 2024 Jun 6 doi: 10.1016/j.ophtha.2024.05.024. PMID: 38849055
Improved sensitivity of microperimetric outcomes for clinical studies in age-related macular degeneration.
Barkana Y, Pondorfer SG, Schmitz-Valckenberg S, Russ H, Finger RP
Sci Rep 2021 Feb 26;11(1):4764. doi: 10.1038/s41598-021-83716-w. PMID: 33637858Free PMC Article
Lymphoma-associated retinopathy.
To KW, Thirkill CE, Jakobiec FA, Lessell S, Berson EL
Ophthalmology 2002 Nov;109(11):2149-53. doi: 10.1016/s0161-6420(02)01261-7. PMID: 12414431
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.
Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO
Arch Ophthalmol 2002 Jun;120(6):701-13; discussion 829-30. doi: 10.1001/archopht.120.6.701. PMID: 12049574
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Age-Related Eye Disease Study Research Group
Arch Ophthalmol 2001 Oct;119(10):1417-36. doi: 10.1001/archopht.119.10.1417. PMID: 11594942Free PMC Article

Prognosis

Genotypic and Phenotypic Spectrum of Foveal Hypoplasia: A Multicenter Study.
Kuht HJ, Maconachie GDE, Han J, Kessel L, van Genderen MM, McLean RJ, Hisaund M, Tu Z, Hertle RW, Gronskov K, Bai D, Wei A, Li W, Jiao Y, Smirnov V, Choi JH, Tobin MD, Sheth V, Purohit R, Dawar B, Girach A, Strul S, May L, Chen FK, Heath Jeffery RC, Aamir A, Sano R, Jin J, Brooks BP, Kohl S, Arveiler B, Montoliu L, Engle EC, Proudlock FA, Nishad G, Pani P, Varma G, Gottlob I, Thomas MG
Ophthalmology 2022 Jun;129(6):708-718. Epub 2022 Feb 11 doi: 10.1016/j.ophtha.2022.02.010. PMID: 35157951Free PMC Article
Scleral tunnel phacoemulsification: Approach for eyes with severe microcornea.
Khokhar S, Gupta S, Tewari R, Agarwal R, Gogia V, Sinha G, Agarwal T
Indian J Ophthalmol 2016 Apr;64(4):320-2. doi: 10.4103/0301-4738.182949. PMID: 27221687Free PMC Article
Autofluorescence patterns as a predictive factor for neovascularization.
Batioğlu F, Demirel S, Ozmert E, Oguz YG, Ozyol P
Optom Vis Sci 2014 Aug;91(8):950-5. doi: 10.1097/OPX.0000000000000321. PMID: 24987815
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.
Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO
Arch Ophthalmol 2002 Jun;120(6):701-13; discussion 829-30. doi: 10.1001/archopht.120.6.701. PMID: 12049574
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Age-Related Eye Disease Study Research Group
Arch Ophthalmol 2001 Oct;119(10):1417-36. doi: 10.1001/archopht.119.10.1417. PMID: 11594942Free PMC Article

Clinical prediction guides

Osseous and Adipocytic Differentiations in the Intraocular Lens and Vitreous.
Jakobiec FA, Ma L, Wolkow N, Cameron JD, Maltry AC
Am J Ophthalmol 2018 Feb;186:77-88. Epub 2017 Nov 27 doi: 10.1016/j.ajo.2017.11.014. PMID: 29191662
Autofluorescence patterns as a predictive factor for neovascularization.
Batioğlu F, Demirel S, Ozmert E, Oguz YG, Ozyol P
Optom Vis Sci 2014 Aug;91(8):950-5. doi: 10.1097/OPX.0000000000000321. PMID: 24987815
Macular dystrophy in Heimler syndrome.
Lima LH, Barbazetto IA, Chen R, Yannuzzi LA, Tsang SH, Spaide RF
Ophthalmic Genet 2011 Jun;32(2):97-100. Epub 2011 Mar 2 doi: 10.3109/13816810.2010.551797. PMID: 21366429Free PMC Article
The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.
Kass MA, Heuer DK, Higginbotham EJ, Johnson CA, Keltner JL, Miller JP, Parrish RK 2nd, Wilson MR, Gordon MO
Arch Ophthalmol 2002 Jun;120(6):701-13; discussion 829-30. doi: 10.1001/archopht.120.6.701. PMID: 12049574
A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8.
Age-Related Eye Disease Study Research Group
Arch Ophthalmol 2001 Oct;119(10):1417-36. doi: 10.1001/archopht.119.10.1417. PMID: 11594942Free PMC Article

Recent systematic reviews

Diagnostic methods for dysthyroid optic neuropathy: A systematic review and analysis.
Sio SWC, Chan BKT, Aljufairi FMAA, Sebastian JU, Lai KKH, Tham CCY, Pang CP, Chong KKL
Surv Ophthalmol 2024 May-Jun;69(3):403-410. Epub 2023 Nov 23 doi: 10.1016/j.survophthal.2023.11.009. PMID: 38007201
Anti-vascular endothelial growth factor for neovascular glaucoma.
Rittiphairoj T, Roberti G, Michelessi M
Cochrane Database Syst Rev 2023 Apr 3;4(4):CD007920. doi: 10.1002/14651858.CD007920.pub4. PMID: 37010901Free PMC Article
Radiotherapy for neovascular age-related macular degeneration.
Evans JR, Igwe C, Jackson TL, Chong V
Cochrane Database Syst Rev 2020 Aug 26;8(8):CD004004. doi: 10.1002/14651858.CD004004.pub4. PMID: 32844399Free PMC Article
Anti-vascular endothelial growth factor for neovascular glaucoma.
Simha A, Aziz K, Braganza A, Abraham L, Samuel P, Lindsley KB
Cochrane Database Syst Rev 2020 Feb 6;2(2):CD007920. doi: 10.1002/14651858.CD007920.pub3. PMID: 32027392Free PMC Article
Surgical Options and Outcomes in the Treatment of Optic Pit Maculopathy: A Meta-analysis and Systematic Review.
Zheng A, Singh RP, Lavine JA
Ophthalmol Retina 2020 Mar;4(3):289-299. Epub 2019 Nov 21 doi: 10.1016/j.oret.2019.10.011. PMID: 31937471

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...