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Astrocytoma, increased risk of

MedGen UID:
897068
•Concept ID:
C4228333
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAstrocytoma, increased risk of

Professional guidelines

PubMed

A Population-Based Study of Treatment and Survival in Older Glioma Patients.
Reiner AS, Lobaugh SM, Gonen S, Diamond EL, Panageas KS
JNCI Cancer Spectr 2022 Jan 5;6(1) doi: 10.1093/jncics/pkac010. PMID: 35699501Free PMC Article
Treatment of newly diagnosed glioblastoma in the elderly: a network meta-analysis.
Hanna C, Lawrie TA, Rogozińska E, Kernohan A, Jefferies S, Bulbeck H, Ali UM, Robinson T, Grant R
Cochrane Database Syst Rev 2020 Mar 23;3(3):CD013261. doi: 10.1002/14651858.CD013261.pub2. PMID: 32202316Free PMC Article
Diffuse low-grade glioma: a review on the new molecular classification, natural history and current management strategies.
Delgado-López PD, Corrales-García EM, Martino J, Lastra-Aras E, Dueñas-Polo MT
Clin Transl Oncol 2017 Aug;19(8):931-944. Epub 2017 Mar 2 doi: 10.1007/s12094-017-1631-4. PMID: 28255650

Recent clinical studies

Etiology

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma.
Tong S, Xia M, Xu Y, Sun Q, Ye L, Yuan F, Wang Y, Cai J, Ye Z, Tian D
J Transl Med 2023 Feb 22;21(1):136. doi: 10.1186/s12967-023-03970-6. PMID: 36814293Free PMC Article
Multifunctional mRNA-Based CAR T Cells Display Promising Antitumor Activity Against Glioblastoma.
Meister H, Look T, Roth P, Pascolo S, Sahin U, Lee S, Hale BD, Snijder B, Regli L, Ravi VM, Heiland DH, Sentman CL, Weller M, Weiss T
Clin Cancer Res 2022 Nov 1;28(21):4747-4756. doi: 10.1158/1078-0432.CCR-21-4384. PMID: 36037304
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850
Encephalocraniocutaneous Lipomatosis.
Bavle A, Shah R, Gross N, Gavula T, Ruiz-Elizalde A, Wierenga K, McNall-Knapp R
J Pediatr Hematol Oncol 2018 Oct;40(7):553-554. doi: 10.1097/MPH.0000000000001170. PMID: 29683947

Diagnosis

Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
Tuberous Sclerosis: Current Update.
Wang MX, Segaran N, Bhalla S, Pickhardt PJ, Lubner MG, Katabathina VS, Ganeshan D
Radiographics 2021 Nov-Dec;41(7):1992-2010. Epub 2021 Sep 17 doi: 10.1148/rg.2021210103. PMID: 34534018
An update on the central nervous system manifestations of neurofibromatosis type 1.
Nix JS, Blakeley J, Rodriguez FJ
Acta Neuropathol 2020 Apr;139(4):625-641. Epub 2019 Apr 8 doi: 10.1007/s00401-019-02002-2. PMID: 30963251Free PMC Article
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA
Nature 2019 Jan;565(7738):234-239. Epub 2018 Dec 19 doi: 10.1038/s41586-018-0792-9. PMID: 30568305Free PMC Article
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ Jr, Mehta MP
N Engl J Med 2014 Feb 20;370(8):699-708. doi: 10.1056/NEJMoa1308573. PMID: 24552317Free PMC Article

Therapy

Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma With Prior Disease Progression.
Cheung IY, Cheung NV, Modak S, Mauguen A, Feng Y, Basu E, Roberts SS, Ragupathi G, Kushner BH
J Clin Oncol 2021 Jan 20;39(3):215-226. Epub 2020 Dec 16 doi: 10.1200/JCO.20.01892. PMID: 33326254Free PMC Article
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial.
Keskin DB, Anandappa AJ, Sun J, Tirosh I, Mathewson ND, Li S, Oliveira G, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K, Iorgulescu JB, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J, Lane WJ, Salazar AM, Daley H, Wen PY, Chiocca EA, Harden M, Lennon NJ, Gabriel S, Getz G, Lander ES, Regev A, Ritz J, Neuberg D, Rodig SJ, Ligon KL, Suvà ML, Wucherpfennig KW, Hacohen N, Fritsch EF, Livak KJ, Ott PA, Wu CJ, Reardon DA
Nature 2019 Jan;565(7738):234-239. Epub 2018 Dec 19 doi: 10.1038/s41586-018-0792-9. PMID: 30568305Free PMC Article
A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Gilbert MR, Dignam JJ, Armstrong TS, Wefel JS, Blumenthal DT, Vogelbaum MA, Colman H, Chakravarti A, Pugh S, Won M, Jeraj R, Brown PD, Jaeckle KA, Schiff D, Stieber VW, Brachman DG, Werner-Wasik M, Tremont-Lukats IW, Sulman EP, Aldape KD, Curran WJ Jr, Mehta MP
N Engl J Med 2014 Feb 20;370(8):699-708. doi: 10.1056/NEJMoa1308573. PMID: 24552317Free PMC Article

Prognosis

Benign Glioma.
Wu PB, Filley AC, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:31-71. doi: 10.1007/978-3-031-23705-8_2. PMID: 37452934
Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma.
Tong S, Xia M, Xu Y, Sun Q, Ye L, Yuan F, Wang Y, Cai J, Ye Z, Tian D
J Transl Med 2023 Feb 22;21(1):136. doi: 10.1186/s12967-023-03970-6. PMID: 36814293Free PMC Article
Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
Survival Impact of Anti-GD2 Antibody Response in a Phase II Ganglioside Vaccine Trial Among Patients With High-Risk Neuroblastoma With Prior Disease Progression.
Cheung IY, Cheung NV, Modak S, Mauguen A, Feng Y, Basu E, Roberts SS, Ragupathi G, Kushner BH
J Clin Oncol 2021 Jan 20;39(3):215-226. Epub 2020 Dec 16 doi: 10.1200/JCO.20.01892. PMID: 33326254Free PMC Article
Molecular targeted therapy of glioblastoma.
Le Rhun E, Preusser M, Roth P, Reardon DA, van den Bent M, Wen P, Reifenberger G, Weller M
Cancer Treat Rev 2019 Nov;80:101896. Epub 2019 Sep 11 doi: 10.1016/j.ctrv.2019.101896. PMID: 31541850

Clinical prediction guides

Identification and validation of a novel prognostic signature based on mitochondria and oxidative stress related genes for glioblastoma.
Tong S, Xia M, Xu Y, Sun Q, Ye L, Yuan F, Wang Y, Cai J, Ye Z, Tian D
J Transl Med 2023 Feb 22;21(1):136. doi: 10.1186/s12967-023-03970-6. PMID: 36814293Free PMC Article
Identification of SSBP1 as a ferroptosis-related biomarker of glioblastoma based on a novel mitochondria-related gene risk model and in vitro experiments.
Su J, Li Y, Liu Q, Peng G, Qin C, Li Y
J Transl Med 2022 Sep 30;20(1):440. doi: 10.1186/s12967-022-03657-4. PMID: 36180956Free PMC Article
The N(6)-Methyladenosine-Modified Pseudogene HSPA7 Correlates With the Tumor Microenvironment and Predicts the Response to Immune Checkpoint Therapy in Glioblastoma.
Zhao R, Li B, Zhang S, He Z, Pan Z, Guo Q, Qiu W, Qi Y, Zhao S, Wang S, Chen Z, Zhang P, Guo X, Xue H, Li G
Front Immunol 2021;12:653711. Epub 2021 Jul 20 doi: 10.3389/fimmu.2021.653711. PMID: 34354698Free PMC Article
Diffuse low-grade glioma: a review on the new molecular classification, natural history and current management strategies.
Delgado-López PD, Corrales-García EM, Martino J, Lastra-Aras E, Dueñas-Polo MT
Clin Transl Oncol 2017 Aug;19(8):931-944. Epub 2017 Mar 2 doi: 10.1007/s12094-017-1631-4. PMID: 28255650
Childhood brain tumors.
Sklar CA
J Pediatr Endocrinol Metab 2002 May;15 Suppl 2:669-73. doi: 10.1515/jpem.2002.15.s2.669. PMID: 12092679

Recent systematic reviews

Treatment of newly diagnosed glioblastoma in the elderly: a network meta-analysis.
Hanna C, Lawrie TA, Rogozińska E, Kernohan A, Jefferies S, Bulbeck H, Ali UM, Robinson T, Grant R
Cochrane Database Syst Rev 2020 Mar 23;3(3):CD013261. doi: 10.1002/14651858.CD013261.pub2. PMID: 32202316Free PMC Article
A systematic review of outcome in intramedullary ependymoma and astrocytoma.
Hamilton KR, Lee SS, Urquhart JC, Jonker BP
J Clin Neurosci 2019 May;63:168-175. Epub 2019 Mar 2 doi: 10.1016/j.jocn.2019.02.001. PMID: 30833131
Type 2 Diabetes Mellitus and Glioblastoma Multiforme-Assessing Risk and Survival: Results of a Large Retrospective Study and Systematic Review of the Literature.
Barami K, Lyon L, Conell C
World Neurosurg 2017 Oct;106:300-307. Epub 2017 Jul 8 doi: 10.1016/j.wneu.2017.06.164. PMID: 28698089
Anthropometrics at birth and risk of a primary central nervous system tumour: A systematic review and meta-analysis.
Georgakis MK, Kalogirou EI, Liaskas A, Karalexi MA, Papathoma P, Ladopoulou K, Kantzanou M, Tsivgoulis G; NARECHEM-BT Working Group, Petridou ET
Eur J Cancer 2017 Apr;75:117-131. Epub 2017 Feb 20 doi: 10.1016/j.ejca.2016.12.033. PMID: 28219020
Rash to the mTOR inhibitor everolimus: systematic review and meta-analysis.
Ramirez-Fort MK, Case EC, Rosen AC, Cerci FB, Wu S, Lacouture ME
Am J Clin Oncol 2014 Jun;37(3):266-71. doi: 10.1097/COC.0b013e318277d62f. PMID: 23241507

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