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Abnormality of fibrinolysis

MedGen UID:
898209
Concept ID:
C4280719
Finding
Synonym: Abnormality of the fibrinolytic system
 
HPO: HP:0040224

Definition

Clincial phenotype characterized by delayed bleeding accelerated break down of blood clot (fibrinolysis) [from HPO]

Professional guidelines

PubMed

Iba T, Umemura Y, Wada H, Levy JH
Arch Med Res 2021 Nov;52(8):788-797. Epub 2021 Jul 31 doi: 10.1016/j.arcmed.2021.07.003. PMID: 34344558
Casini A, Neerman-Arbez M, Ariëns RA, de Moerloose P
J Thromb Haemost 2015 Jun;13(6):909-19. Epub 2015 May 2 doi: 10.1111/jth.12916. PMID: 25816717
Whitlock RP, Sun JC, Fremes SE, Rubens FD, Teoh KH
Chest 2012 Feb;141(2 Suppl):e576S-e600S. doi: 10.1378/chest.11-2305. PMID: 22315272Free PMC Article

Recent clinical studies

Etiology

Moore EE, Moore HB, Kornblith LZ, Neal MD, Hoffman M, Mutch NJ, Schöchl H, Hunt BJ, Sauaia A
Nat Rev Dis Primers 2021 Apr 29;7(1):30. doi: 10.1038/s41572-021-00264-3. PMID: 33927200Free PMC Article
Kietsiriroje N, Ariëns RAS, Ajjan RA
Semin Thromb Hemost 2021 Jul;47(5):490-505. Epub 2021 Apr 20 doi: 10.1055/s-0040-1718923. PMID: 33878782
Mukhopadhyay S, Johnson TA, Duru N, Buzza MS, Pawar NR, Sarkar R, Antalis TM
Front Immunol 2019;10:1348. Epub 2019 Jun 14 doi: 10.3389/fimmu.2019.01348. PMID: 31258531Free PMC Article
Yan L, Li X, Liu Z, Zhao Z, Luo Q, Zhao Q, Jin Q, Yu X, Zhang Y
Heart Fail Rev 2019 Nov;24(6):1031-1040. doi: 10.1007/s10741-019-09802-4. PMID: 31087212
Tripodi A
Curr Opin Hematol 2015 Sep;22(5):406-12. doi: 10.1097/MOH.0000000000000164. PMID: 26203733

Diagnosis

Sinnathamby ES, Issa PP, Roberts L, Norwood H, Malone K, Vemulapalli H, Ahmadzadeh S, Cornett EM, Shekoohi S, Kaye AD
Adv Ther 2023 Mar;40(3):814-827. Epub 2023 Jan 7 doi: 10.1007/s12325-022-02401-0. PMID: 36609679Free PMC Article
Iba T, Umemura Y, Wada H, Levy JH
Arch Med Res 2021 Nov;52(8):788-797. Epub 2021 Jul 31 doi: 10.1016/j.arcmed.2021.07.003. PMID: 34344558
Moore EE, Moore HB, Kornblith LZ, Neal MD, Hoffman M, Mutch NJ, Schöchl H, Hunt BJ, Sauaia A
Nat Rev Dis Primers 2021 Apr 29;7(1):30. doi: 10.1038/s41572-021-00264-3. PMID: 33927200Free PMC Article
Johnson ED, Schell JC, Rodgers GM
Am J Hematol 2019 Jul;94(7):833-839. Epub 2019 Apr 19 doi: 10.1002/ajh.25482. PMID: 30945756
Chapin JC, Hajjar KA
Blood Rev 2015 Jan;29(1):17-24. Epub 2014 Sep 16 doi: 10.1016/j.blre.2014.09.003. PMID: 25294122Free PMC Article

Therapy

Chowdary P
Exp Physiol 2022 Jul;107(7):749-758. Epub 2022 Jun 22 doi: 10.1113/EP089404. PMID: 35733235Free PMC Article
Asakura H, Ogawa H
Int J Hematol 2021 Jan;113(1):45-57. Epub 2020 Nov 7 doi: 10.1007/s12185-020-03029-y. PMID: 33161508Free PMC Article
Yan L, Li X, Liu Z, Zhao Z, Luo Q, Zhao Q, Jin Q, Yu X, Zhang Y
Heart Fail Rev 2019 Nov;24(6):1031-1040. doi: 10.1007/s10741-019-09802-4. PMID: 31087212
Michaud M, Pourrat J
J Clin Rheumatol 2013 Apr;19(3):142-8. doi: 10.1097/RHU.0b013e318289e06e. PMID: 23519183
Whitlock RP, Sun JC, Fremes SE, Rubens FD, Teoh KH
Chest 2012 Feb;141(2 Suppl):e576S-e600S. doi: 10.1378/chest.11-2305. PMID: 22315272Free PMC Article

Prognosis

Longstaff C
Hamostaseologie 2021 Feb;41(1):69-75. Epub 2021 Feb 15 doi: 10.1055/a-1325-0268. PMID: 33588458
Asakura H, Ogawa H
Int J Hematol 2021 Jan;113(1):45-57. Epub 2020 Nov 7 doi: 10.1007/s12185-020-03029-y. PMID: 33161508Free PMC Article
Chapin JC, Hajjar KA
Blood Rev 2015 Jan;29(1):17-24. Epub 2014 Sep 16 doi: 10.1016/j.blre.2014.09.003. PMID: 25294122Free PMC Article
Girolami A, Scarparo P, Candeo N, Lombardi AM
Expert Rev Hematol 2010 Dec;3(6):685-95. doi: 10.1586/ehm.10.69. PMID: 21091145
Spraul CW, Grossniklaus HE
Surv Ophthalmol 1997 Jul-Aug;42(1):3-39. doi: 10.1016/s0039-6257(97)84041-6. PMID: 9265701

Clinical prediction guides

Iba T, Umemura Y, Wada H, Levy JH
Arch Med Res 2021 Nov;52(8):788-797. Epub 2021 Jul 31 doi: 10.1016/j.arcmed.2021.07.003. PMID: 34344558
Longstaff C
Hamostaseologie 2021 Feb;41(1):69-75. Epub 2021 Feb 15 doi: 10.1055/a-1325-0268. PMID: 33588458
Mukhopadhyay S, Johnson TA, Duru N, Buzza MS, Pawar NR, Sarkar R, Antalis TM
Front Immunol 2019;10:1348. Epub 2019 Jun 14 doi: 10.3389/fimmu.2019.01348. PMID: 31258531Free PMC Article
Tripodi A
Curr Opin Hematol 2015 Sep;22(5):406-12. doi: 10.1097/MOH.0000000000000164. PMID: 26203733
Chapin JC, Hajjar KA
Blood Rev 2015 Jan;29(1):17-24. Epub 2014 Sep 16 doi: 10.1016/j.blre.2014.09.003. PMID: 25294122Free PMC Article

Recent systematic reviews

Xu Q, Wang Y, Shen X, Zhang Y, Fan Q, Zhang W
Front Endocrinol (Lausanne) 2022;13:861746. Epub 2022 Apr 29 doi: 10.3389/fendo.2022.861746. PMID: 35574019Free PMC Article
Katsaras GΝ, Sokou R, Tsantes AG, Piovani D, Bonovas S, Konstantinidi A, Ioakeimidis G, Parastatidou S, Gialamprinou D, Makrogianni A, Mitsiakos G, Tsantes AΕ
Eur J Pediatr 2021 Dec;180(12):3455-3470. Epub 2021 Jun 16 doi: 10.1007/s00431-021-04154-4. PMID: 34131816
Lin Y, Liu Z, Qiu Y, Zhang J, Wu H, Liang R, Chen G, Qin G, Li Y, Zou D
Eur J Surg Oncol 2018 Oct;44(10):1494-1503. Epub 2018 Jul 31 doi: 10.1016/j.ejso.2018.07.052. PMID: 30100361
Wiyeh AB, Ochodo EA, Wiysonge CS, Kakia A, Awotedu AA, Ristic A, Mayosi BM
Int J Cardiol 2018 Jan 1;250:223-228. Epub 2017 Nov 6 doi: 10.1016/j.ijcard.2017.10.049. PMID: 29107356
Müller MC, Meijers JC, Vroom MB, Juffermans NP
Crit Care 2014 Feb 10;18(1):R30. doi: 10.1186/cc13721. PMID: 24512650Free PMC Article

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