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Increased susceptibility to malignancy

MedGen UID:
899618
•Concept ID:
C4228779
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVIncreased susceptibility to malignancy

Professional guidelines

PubMed

Cutaneous manifestations of internal malignancy: diagnosis and management.
Kleyn CE, Lai-Cheong JE, Bell HK
Am J Clin Dermatol 2006;7(2):71-84. doi: 10.2165/00128071-200607020-00001. PMID: 16605288
Glutathione S-transferase GSTM1 null genotype is not overrepresented in Australian patients with nevoid basal cell carcinoma syndrome or sporadic melanoma.
Shanley SM, Chenevix-Trench G, Palmer J, Hayward N
Carcinogenesis 1995 Aug;16(8):2003-4. doi: 10.1093/carcin/16.8.2003. PMID: 7634433

Recent clinical studies

Etiology

The Oral Microbiome and Cancer.
Irfan M, Delgado RZR, Frias-Lopez J
Front Immunol 2020;11:591088. Epub 2020 Oct 23 doi: 10.3389/fimmu.2020.591088. PMID: 33193429Free PMC Article
Cancer Stem Cells-Origins and Biomarkers: Perspectives for Targeted Personalized Therapies.
Walcher L, Kistenmacher AK, Suo H, Kitte R, Dluczek S, Strauß A, Blaudszun AR, Yevsa T, Fricke S, Kossatz-Boehlert U
Front Immunol 2020;11:1280. Epub 2020 Aug 7 doi: 10.3389/fimmu.2020.01280. PMID: 32849491Free PMC Article
Diagnosis and Treatment of Breast Cancer in Young Women.
Rossi L, Mazzara C, Pagani O
Curr Treat Options Oncol 2019 Nov 27;20(12):86. doi: 10.1007/s11864-019-0685-7. PMID: 31776799
Molecular Pathogenesis of Cholangiocarcinoma.
Labib PL, Goodchild G, Pereira SP
BMC Cancer 2019 Feb 28;19(1):185. doi: 10.1186/s12885-019-5391-0. PMID: 30819129Free PMC Article
Cutaneous Squamous Cell Carcinoma.
Waldman A, Schmults C
Hematol Oncol Clin North Am 2019 Feb;33(1):1-12. doi: 10.1016/j.hoc.2018.08.001. PMID: 30497667

Diagnosis

Updates on targeted therapies for acute myeloid leukaemia.
Kayser S, Levis MJ
Br J Haematol 2022 Jan;196(2):316-328. Epub 2021 Aug 4 doi: 10.1111/bjh.17746. PMID: 34350585
The Oral Microbiome and Cancer.
Irfan M, Delgado RZR, Frias-Lopez J
Front Immunol 2020;11:591088. Epub 2020 Oct 23 doi: 10.3389/fimmu.2020.591088. PMID: 33193429Free PMC Article
Cancer Stem Cells-Origins and Biomarkers: Perspectives for Targeted Personalized Therapies.
Walcher L, Kistenmacher AK, Suo H, Kitte R, Dluczek S, Strauß A, Blaudszun AR, Yevsa T, Fricke S, Kossatz-Boehlert U
Front Immunol 2020;11:1280. Epub 2020 Aug 7 doi: 10.3389/fimmu.2020.01280. PMID: 32849491Free PMC Article
Primary immunodeficiency and autoimmunity: A comprehensive review.
Amaya-Uribe L, Rojas M, Azizi G, Anaya JM, Gershwin ME
J Autoimmun 2019 May;99:52-72. Epub 2019 Feb 20 doi: 10.1016/j.jaut.2019.01.011. PMID: 30795880
Cutaneous Squamous Cell Carcinoma.
Waldman A, Schmults C
Hematol Oncol Clin North Am 2019 Feb;33(1):1-12. doi: 10.1016/j.hoc.2018.08.001. PMID: 30497667

Therapy

Updates on targeted therapies for acute myeloid leukaemia.
Kayser S, Levis MJ
Br J Haematol 2022 Jan;196(2):316-328. Epub 2021 Aug 4 doi: 10.1111/bjh.17746. PMID: 34350585
Ovarian Cancer Immunotherapy and Personalized Medicine.
Morand S, Devanaboyina M, Staats H, Stanbery L, Nemunaitis J
Int J Mol Sci 2021 Jun 18;22(12) doi: 10.3390/ijms22126532. PMID: 34207103Free PMC Article
Inflammatory microenvironment remodelling by tumour cells after radiotherapy.
McLaughlin M, Patin EC, Pedersen M, Wilkins A, Dillon MT, Melcher AA, Harrington KJ
Nat Rev Cancer 2020 Apr;20(4):203-217. Epub 2020 Mar 11 doi: 10.1038/s41568-020-0246-1. PMID: 32161398
Lung Cancer in Never Smokers.
Rivera GA, Wakelee H
Adv Exp Med Biol 2016;893:43-57. doi: 10.1007/978-3-319-24223-1_3. PMID: 26667338
Epidemiology of Lung Cancer.
Schwartz AG, Cote ML
Adv Exp Med Biol 2016;893:21-41. doi: 10.1007/978-3-319-24223-1_2. PMID: 26667337

Prognosis

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection.
Patel SG, Karlitz JJ, Yen T, Lieu CH, Boland CR
Lancet Gastroenterol Hepatol 2022 Mar;7(3):262-274. Epub 2022 Jan 26 doi: 10.1016/S2468-1253(21)00426-X. PMID: 35090605
Melanoma Genomics.
Newton-Bishop J, Bishop DT, Harland M
Acta Derm Venereol 2020 Jun 3;100(11):adv00138. doi: 10.2340/00015555-3493. PMID: 32346746Free PMC Article
Cutaneous Squamous Cell Carcinoma.
Waldman A, Schmults C
Hematol Oncol Clin North Am 2019 Feb;33(1):1-12. doi: 10.1016/j.hoc.2018.08.001. PMID: 30497667
Leukemia.
Juliusson G, Hough R
Prog Tumor Res 2016;43:87-100. Epub 2016 Sep 5 doi: 10.1159/000447076. PMID: 27595359
Epidemiology of Lung Cancer.
Schwartz AG, Cote ML
Adv Exp Med Biol 2016;893:21-41. doi: 10.1007/978-3-319-24223-1_2. PMID: 26667337

Clinical prediction guides

Updates on targeted therapies for acute myeloid leukaemia.
Kayser S, Levis MJ
Br J Haematol 2022 Jan;196(2):316-328. Epub 2021 Aug 4 doi: 10.1111/bjh.17746. PMID: 34350585
Molecular Pathogenesis of Cholangiocarcinoma.
Labib PL, Goodchild G, Pereira SP
BMC Cancer 2019 Feb 28;19(1):185. doi: 10.1186/s12885-019-5391-0. PMID: 30819129Free PMC Article
Predicting and Preventing Anthracycline-Related Cardiotoxicity.
Armenian S, Bhatia S
Am Soc Clin Oncol Educ Book 2018 May 23;38:3-12. doi: 10.1200/EDBK_100015. PMID: 30231396
Lung Cancer in Never Smokers.
Rivera GA, Wakelee H
Adv Exp Med Biol 2016;893:43-57. doi: 10.1007/978-3-319-24223-1_3. PMID: 26667338
Epidemiology of Lung Cancer.
Schwartz AG, Cote ML
Adv Exp Med Biol 2016;893:21-41. doi: 10.1007/978-3-319-24223-1_2. PMID: 26667337

Recent systematic reviews

Vitamin D-Related Genes and Thyroid Cancer-A Systematic Review.
Maciejewski A, Lacka K
Int J Mol Sci 2022 Nov 7;23(21) doi: 10.3390/ijms232113661. PMID: 36362448Free PMC Article
EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer-2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative Intent.
Mottet N, van den Bergh RCN, Briers E, Van den Broeck T, Cumberbatch MG, De Santis M, Fanti S, Fossati N, Gandaglia G, Gillessen S, Grivas N, Grummet J, Henry AM, van der Kwast TH, Lam TB, Lardas M, Liew M, Mason MD, Moris L, Oprea-Lager DE, van der Poel HG, Rouvière O, Schoots IG, Tilki D, Wiegel T, Willemse PM, Cornford P
Eur Urol 2021 Feb;79(2):243-262. Epub 2020 Nov 7 doi: 10.1016/j.eururo.2020.09.042. PMID: 33172724
Risk-reducing mastectomy for the prevention of primary breast cancer.
Carbine NE, Lostumbo L, Wallace J, Ko H
Cochrane Database Syst Rev 2018 Apr 5;4(4):CD002748. doi: 10.1002/14651858.CD002748.pub4. PMID: 29620792Free PMC Article
Risk Factors for Cutaneous Squamous Cell Carcinoma Recurrence, Metastasis, and Disease-Specific Death: A Systematic Review and Meta-analysis.
Thompson AK, Kelley BF, Prokop LJ, Murad MH, Baum CL
JAMA Dermatol 2016 Apr;152(4):419-28. doi: 10.1001/jamadermatol.2015.4994. PMID: 26762219Free PMC Article
Benefits and Harms of Breast Cancer Screening: A Systematic Review.
Myers ER, Moorman P, Gierisch JM, Havrilesky LJ, Grimm LJ, Ghate S, Davidson B, Mongtomery RC, Crowley MJ, McCrory DC, Kendrick A, Sanders GD
JAMA 2015 Oct 20;314(15):1615-34. doi: 10.1001/jama.2015.13183. PMID: 26501537

Supplemental Content

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    Practice guidelines

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