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Childhood Mixed Germ Cell Tumor

MedGen UID:
900715
Concept ID:
C4086164
Neoplastic Process

Definition

A mixed germ cell tumor occurring in children. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Mixed Germ Cell Tumor

Professional guidelines

PubMed

Brown S, Chowdhury T, Collin M, Grundy RG, Howell L, Ramanujachar R, Rees H, Vora A, Gray JC, Bate J
Pediatr Blood Cancer 2023 Mar;70(3):e30159. Epub 2022 Dec 24 doi: 10.1002/pbc.30159. PMID: 36565277
Yeo KK, Nagabushan S, Dhall G, Abdelbaki MS
Neoplasia 2023 Feb;36:100860. Epub 2022 Dec 13 doi: 10.1016/j.neo.2022.100860. PMID: 36521378Free PMC Article
Güler E, Tezer Kutluk M, Büyükpamukçu N, Caglar M, Varan A, Akyüz C, Büyükpamukçu M
Pediatr Hematol Oncol 2004 Jan-Feb;21(1):49-56. PMID: 14660306

Recent clinical studies

Etiology

Schraw JM, Petridou ET, Bonaventure A, Dockerty JD, Karalexi M, Ntzani E, Infante-Rivard C, Clavel J, Bracci PM, McKean-Cowdin R, Roman E, Kane E, Erdmann F, Schüz J, Mueller BA, Scheurer ME
Cancer Causes Control 2023 Nov;34(11):1005-1015. Epub 2023 Jul 8 doi: 10.1007/s10552-023-01746-3. PMID: 37421504
Schraw JM, Sok P, Desrosiers TA, Janitz AE, Langlois PH, Canfield MA, Frazier AL, Plon SE, Lupo PJ, Poynter JN
Cancer 2023 Oct 15;129(20):3300-3308. Epub 2023 Jun 27 doi: 10.1002/cncr.34906. PMID: 37366624Free PMC Article
Vladoiu MC, El-Hamamy I, Donovan LK, Farooq H, Holgado BL, Sundaravadanam Y, Ramaswamy V, Hendrikse LD, Kumar S, Mack SC, Lee JJY, Fong V, Juraschka K, Przelicki D, Michealraj A, Skowron P, Luu B, Suzuki H, Morrissy AS, Cavalli FMG, Garzia L, Daniels C, Wu X, Qazi MA, Singh SK, Chan JA, Marra MA, Malkin D, Dirks P, Heisler L, Pugh T, Ng K, Notta F, Thompson EM, Kleinman CL, Joyner AL, Jabado N, Stein L, Taylor MD
Nature 2019 Aug;572(7767):67-73. Epub 2019 May 1 doi: 10.1038/s41586-019-1158-7. PMID: 31043743Free PMC Article
Al-Hussain T, Bakshi N, Akhtar M
Adv Anat Pathol 2015 May;22(3):202-12. doi: 10.1097/PAP.0000000000000066. PMID: 25844678
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075

Diagnosis

Sarnat HB, Chan ES, Ng D, Yu W
J Neuropathol Exp Neurol 2023 Sep 20;82(10):853-864. doi: 10.1093/jnen/nlad068. PMID: 37682248
Schraw JM, Petridou ET, Bonaventure A, Dockerty JD, Karalexi M, Ntzani E, Infante-Rivard C, Clavel J, Bracci PM, McKean-Cowdin R, Roman E, Kane E, Erdmann F, Schüz J, Mueller BA, Scheurer ME
Cancer Causes Control 2023 Nov;34(11):1005-1015. Epub 2023 Jul 8 doi: 10.1007/s10552-023-01746-3. PMID: 37421504
Cordani R, Veneruso M, Napoli F, Milanaccio C, Verrico A, Consales A, Cataldi M, Fava D, Di Iorgi N, Maghnie M, Mancardi MM, Nobili L
J Neurol 2021 Nov;268(11):4362-4369. Epub 2021 Sep 14 doi: 10.1007/s00415-021-10794-1. PMID: 34522989Free PMC Article
Abacı A, Çatlı G, Berberoğlu M
J Pediatr Endocrinol Metab 2015 Sep;28(9-10):1019-27. doi: 10.1515/jpem-2014-0522. PMID: 25879315
Chang CV, Nunes Vdos S, Felicio AC, Zanini MA, Cunha-Neto MB, de Castro AV
Arq Bras Endocrinol Metabol 2008 Dec;52(9):1501-4. doi: 10.1590/s0004-27302008000900015. PMID: 19197460

Therapy

Schraw JM, Petridou ET, Bonaventure A, Dockerty JD, Karalexi M, Ntzani E, Infante-Rivard C, Clavel J, Bracci PM, McKean-Cowdin R, Roman E, Kane E, Erdmann F, Schüz J, Mueller BA, Scheurer ME
Cancer Causes Control 2023 Nov;34(11):1005-1015. Epub 2023 Jul 8 doi: 10.1007/s10552-023-01746-3. PMID: 37421504
Hall C, Hansen J, von Ehrenstein OS, He D, Olsen J, Ritz B, Heck JE
Int Arch Occup Environ Health 2020 Jul;93(5):659-668. Epub 2020 Feb 5 doi: 10.1007/s00420-020-01524-7. PMID: 32025796Free PMC Article
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075
Terenziani M, Massimino M, Casanova M, Cefalo G, Ferrari A, Luksch R, Spreafico F, Polastri D, Fontanelli R, Piva L, Fossati-Bellani F
Gynecol Oncol 2001 Jun;81(3):436-40. doi: 10.1006/gyno.2001.6177. PMID: 11371135
Prados M, Levin V
Pediatr Neurosci 1987;13(3):144-51. doi: 10.1159/000120320. PMID: 3331428

Prognosis

Greimelmaier K, Calaminus G, Kristiansen G, Vokuhl C, Klapper W
Pediatr Blood Cancer 2019 Aug;66(8):e27777. Epub 2019 May 2 doi: 10.1002/pbc.27777. PMID: 31045322
Vladoiu MC, El-Hamamy I, Donovan LK, Farooq H, Holgado BL, Sundaravadanam Y, Ramaswamy V, Hendrikse LD, Kumar S, Mack SC, Lee JJY, Fong V, Juraschka K, Przelicki D, Michealraj A, Skowron P, Luu B, Suzuki H, Morrissy AS, Cavalli FMG, Garzia L, Daniels C, Wu X, Qazi MA, Singh SK, Chan JA, Marra MA, Malkin D, Dirks P, Heisler L, Pugh T, Ng K, Notta F, Thompson EM, Kleinman CL, Joyner AL, Jabado N, Stein L, Taylor MD
Nature 2019 Aug;572(7767):67-73. Epub 2019 May 1 doi: 10.1038/s41586-019-1158-7. PMID: 31043743Free PMC Article
Menyhárt O, Giangaspero F, Győrffy B
J Hematol Oncol 2019 Mar 15;12(1):29. doi: 10.1186/s13045-019-0712-y. PMID: 30876441Free PMC Article
Abacı A, Çatlı G, Berberoğlu M
J Pediatr Endocrinol Metab 2015 Sep;28(9-10):1019-27. doi: 10.1515/jpem-2014-0522. PMID: 25879315
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075

Clinical prediction guides

Schraw JM, Sok P, Desrosiers TA, Janitz AE, Langlois PH, Canfield MA, Frazier AL, Plon SE, Lupo PJ, Poynter JN
Cancer 2023 Oct 15;129(20):3300-3308. Epub 2023 Jun 27 doi: 10.1002/cncr.34906. PMID: 37366624Free PMC Article
Greimelmaier K, Calaminus G, Kristiansen G, Vokuhl C, Klapper W
Pediatr Blood Cancer 2019 Aug;66(8):e27777. Epub 2019 May 2 doi: 10.1002/pbc.27777. PMID: 31045322
Abacı A, Çatlı G, Berberoğlu M
J Pediatr Endocrinol Metab 2015 Sep;28(9-10):1019-27. doi: 10.1515/jpem-2014-0522. PMID: 25879315
Oosterhuis JW, Stoop JA, Rijlaarsdam MA, Biermann K, Smit VT, Hersmus R, Looijenga LH
Andrology 2015 Jan;3(1):70-7. Epub 2014 Nov 27 doi: 10.1111/andr.305. PMID: 25427839
De Backer A, Madern GC, Oosterhuis JW, Hakvoort-Cammel FG, Hazebroek FW
Pediatr Blood Cancer 2006 Apr;46(4):459-64. doi: 10.1002/pbc.20633. PMID: 16206211

Recent systematic reviews

Kreis C, Doessegger E, Lupatsch JE, Spycher BD
Eur J Epidemiol 2019 Jan;34(1):9-21. Epub 2018 Nov 16 doi: 10.1007/s10654-018-0456-y. PMID: 30446850Free PMC Article
McDaid C, Hartley S, Bagnall AM, Ritchie G, Light K, Riemsma R
Health Technol Assess 2005 Dec;9(48):iii, ix-x, 1-145. doi: 10.3310/hta9480. PMID: 16336843

Supplemental Content

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