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Childhood Thyroid Gland Papillary Carcinoma

MedGen UID:
903163
•Concept ID:
C4086178
•
Neoplastic Process

Definition

A papillary thyroid gland carcinoma occurring during childhood. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVChildhood Thyroid Gland Papillary Carcinoma

Professional guidelines

PubMed

Thyroid Dysfunction and Thyroid Cancer in Childhood Cancer Survivors: Prevalence, Surveillance and Management.
Lebbink CA, Waguespack SG, van Santen HM
Front Horm Res 2021;54:140-153. Epub 2021 Mar 9 doi: 10.1159/000513805. PMID: 33690237
Management of pediatric differentiated thyroid cancer: An overview for the pediatric oncologist.
Prasad PK, Mahajan P, Hawkins DS, Mostoufi-Moab S, Venkatramani R
Pediatr Blood Cancer 2020 Jun;67(6):e28141. Epub 2020 Apr 10 doi: 10.1002/pbc.28141. PMID: 32275118
Management of thyroid nodules in children and adolescents.
Wiersinga WM
Hormones (Athens) 2007 Jul-Sep;6(3):194-9. PMID: 17724003

Recent clinical studies

Etiology

Global incidence and prevalence of differentiated thyroid cancer in childhood: systematic review and meta-analysis.
Moleti M, Aversa T, Crisafulli S, Trifirò G, Corica D, Pepe G, Cannavò L, Di Mauro M, Paola G, Fontana A, Calapai F, Cannavò S, Wasniewska M
Front Endocrinol (Lausanne) 2023;14:1270518. Epub 2023 Sep 19 doi: 10.3389/fendo.2023.1270518. PMID: 37795368Free PMC Article
Is Multifocality a Predictor of Poor Outcome in Childhood and Adolescent Papillary Thyroid Carcinoma?
Scholfield DW, Lopez J, Eagan A, Antal Z, Tuttle RM, Ghossein R, LaQuaglia M, Shaha AR, Shah JP, Wong RJ, Patel SG, Ganly I
J Clin Endocrinol Metab 2023 Nov 17;108(12):3135-3144. doi: 10.1210/clinem/dgad369. PMID: 37350510Free PMC Article
Molecular targets of tyrosine kinase inhibitors in thyroid cancer.
Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Distant Metastases From Childhood Differentiated Thyroid Carcinoma: Clinical Course and Mutational Landscape.
Nies M, Vassilopoulou-Sellin R, Bassett RL, Yedururi S, Zafereo ME, Cabanillas ME, Sherman SI, Links TP, Waguespack SG
J Clin Endocrinol Metab 2021 Mar 25;106(4):e1683-e1697. doi: 10.1210/clinem/dgaa935. PMID: 33382403Free PMC Article
Risk Factors for Thyroid Cancer: What Do We Know So Far?
Bogović Crnčić T, Ilić Tomaš M, Girotto N, Grbac Ivanković S
Acta Clin Croat 2020 Jun;59(Suppl 1):66-72. doi: 10.20471/acc.2020.59.s1.08. PMID: 34219886Free PMC Article

Diagnosis

Survival outcomes of low-risk papillary thyroid carcinoma at different risk levels: a corollary for active surveillance.
Ding W, Ruan G, Lin Y, Zhu J, Li Z, Ye D
Front Endocrinol (Lausanne) 2023;14:1235006. Epub 2023 Sep 7 doi: 10.3389/fendo.2023.1235006. PMID: 37745712Free PMC Article
Molecular targets of tyrosine kinase inhibitors in thyroid cancer.
Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Distant Metastases From Childhood Differentiated Thyroid Carcinoma: Clinical Course and Mutational Landscape.
Nies M, Vassilopoulou-Sellin R, Bassett RL, Yedururi S, Zafereo ME, Cabanillas ME, Sherman SI, Links TP, Waguespack SG
J Clin Endocrinol Metab 2021 Mar 25;106(4):e1683-e1697. doi: 10.1210/clinem/dgaa935. PMID: 33382403Free PMC Article
Risk Factors for Thyroid Cancer: What Do We Know So Far?
Bogović Crnčić T, Ilić Tomaš M, Girotto N, Grbac Ivanković S
Acta Clin Croat 2020 Jun;59(Suppl 1):66-72. doi: 10.20471/acc.2020.59.s1.08. PMID: 34219886Free PMC Article
Thyroid nodules and thyroid autoimmunity in the context of environmental pollution.
Benvenga S, Antonelli A, Vita R
Rev Endocr Metab Disord 2015 Dec;16(4):319-40. doi: 10.1007/s11154-016-9327-6. PMID: 26825072

Therapy

Nefarious NTRK oncogenic fusions in pediatric sarcomas: Too many to Trk.
Aepala MR, Peiris MN, Jiang Z, Yang W, Meyer AN, Donoghue DJ
Cytokine Growth Factor Rev 2022 Dec;68:93-106. Epub 2022 Aug 27 doi: 10.1016/j.cytogfr.2022.08.003. PMID: 36153202
Molecular targets of tyrosine kinase inhibitors in thyroid cancer.
Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Thyroid Dysfunction and Thyroid Cancer in Childhood Cancer Survivors: Prevalence, Surveillance and Management.
Lebbink CA, Waguespack SG, van Santen HM
Front Horm Res 2021;54:140-153. Epub 2021 Mar 9 doi: 10.1159/000513805. PMID: 33690237
Somatic health effects of Chernobyl: 30 years on.
Hatch M, Cardis E
Eur J Epidemiol 2017 Dec;32(12):1047-1054. Epub 2017 Sep 19 doi: 10.1007/s10654-017-0303-6. PMID: 28929329
Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure.
Ho WL, Zacharin MR
Eur J Pediatr 2016 May;175(5):677-83. Epub 2016 Jan 25 doi: 10.1007/s00431-016-2692-z. PMID: 26805408

Prognosis

Global incidence and prevalence of differentiated thyroid cancer in childhood: systematic review and meta-analysis.
Moleti M, Aversa T, Crisafulli S, Trifirò G, Corica D, Pepe G, Cannavò L, Di Mauro M, Paola G, Fontana A, Calapai F, Cannavò S, Wasniewska M
Front Endocrinol (Lausanne) 2023;14:1270518. Epub 2023 Sep 19 doi: 10.3389/fendo.2023.1270518. PMID: 37795368Free PMC Article
Is Multifocality a Predictor of Poor Outcome in Childhood and Adolescent Papillary Thyroid Carcinoma?
Scholfield DW, Lopez J, Eagan A, Antal Z, Tuttle RM, Ghossein R, LaQuaglia M, Shaha AR, Shah JP, Wong RJ, Patel SG, Ganly I
J Clin Endocrinol Metab 2023 Nov 17;108(12):3135-3144. doi: 10.1210/clinem/dgad369. PMID: 37350510Free PMC Article
Molecular targets of tyrosine kinase inhibitors in thyroid cancer.
Fallahi P, Ferrari SM, Galdiero MR, Varricchi G, Elia G, Ragusa F, Paparo SR, Benvenga S, Antonelli A
Semin Cancer Biol 2022 Feb;79:180-196. Epub 2020 Nov 26 doi: 10.1016/j.semcancer.2020.11.013. PMID: 33249201
Risk Factors for Thyroid Cancer: What Do We Know So Far?
Bogović Crnčić T, Ilić Tomaš M, Girotto N, Grbac Ivanković S
Acta Clin Croat 2020 Jun;59(Suppl 1):66-72. doi: 10.20471/acc.2020.59.s1.08. PMID: 34219886Free PMC Article
BRAF Status in Papillary Microcarcinomas of the Thyroid Gland: a Brief Review.
Ieni A, Vita R, Cardia R, Giuffré G, Benvenga S, Tuccari G
Curr Mol Med 2019;19(9):665-672. doi: 10.2174/1566524019666190717161359. PMID: 31625469

Clinical prediction guides

Survival outcomes of low-risk papillary thyroid carcinoma at different risk levels: a corollary for active surveillance.
Ding W, Ruan G, Lin Y, Zhu J, Li Z, Ye D
Front Endocrinol (Lausanne) 2023;14:1235006. Epub 2023 Sep 7 doi: 10.3389/fendo.2023.1235006. PMID: 37745712Free PMC Article
Is Multifocality a Predictor of Poor Outcome in Childhood and Adolescent Papillary Thyroid Carcinoma?
Scholfield DW, Lopez J, Eagan A, Antal Z, Tuttle RM, Ghossein R, LaQuaglia M, Shaha AR, Shah JP, Wong RJ, Patel SG, Ganly I
J Clin Endocrinol Metab 2023 Nov 17;108(12):3135-3144. doi: 10.1210/clinem/dgad369. PMID: 37350510Free PMC Article
Trends and Outcomes of Surgical Management of Primary Papillary Carcinoma in the Pediatric Population.
Sharma RK, Huang B, Lee JA, Kuo JH
J Surg Res 2021 Jul;263:207-214. Epub 2021 Mar 6 doi: 10.1016/j.jss.2021.01.043. PMID: 33690052
Radiation-induced papillary thyroid cancer: is it a distinct clinical entity?
Bresciani L, Orlandi E, Piazza C
Curr Opin Otolaryngol Head Neck Surg 2019 Apr;27(2):117-122. doi: 10.1097/MOO.0000000000000522. PMID: 30664052
Preoperatively undiagnosed papillary thyroid carcinoma in patients thyroidectomized for benign multinodular goiter.
Fama F, Sindoni A, Cicciu M, Polito F, Piquard A, Saint-Marc O, Gioffre-Florio M, Benvenga S
Arch Endocrinol Metab 2018 Mar-Apr;62(2):139-148. Epub 2018 Apr 5 doi: 10.20945/2359-3997000000017. PMID: 29641730Free PMC Article

Recent systematic reviews

Global incidence and prevalence of differentiated thyroid cancer in childhood: systematic review and meta-analysis.
Moleti M, Aversa T, Crisafulli S, Trifirò G, Corica D, Pepe G, Cannavò L, Di Mauro M, Paola G, Fontana A, Calapai F, Cannavò S, Wasniewska M
Front Endocrinol (Lausanne) 2023;14:1270518. Epub 2023 Sep 19 doi: 10.3389/fendo.2023.1270518. PMID: 37795368Free PMC Article
Somatic health effects of Chernobyl: 30 years on.
Hatch M, Cardis E
Eur J Epidemiol 2017 Dec;32(12):1047-1054. Epub 2017 Sep 19 doi: 10.1007/s10654-017-0303-6. PMID: 28929329

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