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Myelogeneous leukemia, chronic

MedGen UID:
907046
•Concept ID:
C4227553
•
Finding

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVMyelogeneous leukemia, chronic

Professional guidelines

PubMed

Management of chronic myeloid leukemia in 2023 - common ground and common sense.
Senapati J, Sasaki K, Issa GC, Lipton JH, Radich JP, Jabbour E, Kantarjian HM
Blood Cancer J 2023 Apr 24;13(1):58. doi: 10.1038/s41408-023-00823-9. PMID: 37088793Free PMC Article
Pathogenesis and management of accelerated and blast phases of chronic myeloid leukemia.
Senapati J, Jabbour E, Kantarjian H, Short NJ
Leukemia 2023 Jan;37(1):5-17. Epub 2022 Oct 29 doi: 10.1038/s41375-022-01736-5. PMID: 36309558
Chronic Myeloid Leukemia, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology.
Deininger MW, Shah NP, Altman JK, Berman E, Bhatia R, Bhatnagar B, DeAngelo DJ, Gotlib J, Hobbs G, Maness L, Mead M, Metheny L, Mohan S, Moore JO, Naqvi K, Oehler V, Pallera AM, Patnaik M, Pratz K, Pusic I, Rose MG, Smith BD, Snyder DS, Sweet KL, Talpaz M, Thompson J, Yang DT, Gregory KM, Sundar H
J Natl Compr Canc Netw 2020 Oct 1;18(10):1385-1415. doi: 10.6004/jnccn.2020.0047. PMID: 33022644

Recent clinical studies

Etiology

Measurable residual disease in chronic myeloid leukemia.
Branford S, Apperley JF
Haematologica 2022 Dec 1;107(12):2794-2809. doi: 10.3324/haematol.2022.281493. PMID: 36453517Free PMC Article
Treatment of blast phase chronic myeloid leukaemia: A rare and challenging entity.
Copland M
Br J Haematol 2022 Dec;199(5):665-678. Epub 2022 Jul 22 doi: 10.1111/bjh.18370. PMID: 35866251Free PMC Article
Venetoclax and BCR-ABL Tyrosine Kinase Inhibitor Combinations: Outcome in Patients with Philadelphia Chromosome-Positive Advanced Myeloid Leukemias.
Maiti A, Franquiz MJ, Ravandi F, Cortes JE, Jabbour EJ, Sasaki K, Marx K, Daver NG, Kadia TM, Konopleva MY, Masarova L, Borthakur G, DiNardo CD, Naqvi K, Pierce S, Kantarjian HM, Short NJ
Acta Haematol 2020;143(6):567-573. Epub 2020 Apr 14 doi: 10.1159/000506346. PMID: 32289808Free PMC Article
Management of chronic myeloid leukemia in children and adolescents: Recommendations from the Children's Oncology Group CML Working Group.
Athale U, Hijiya N, Patterson BC, Bergsagel J, Andolina JR, Bittencourt H, Schultz KR, Burke MJ, Redell MS, Kolb EA, Johnston DL
Pediatr Blood Cancer 2019 Sep;66(9):e27827. Epub 2019 Jun 10 doi: 10.1002/pbc.27827. PMID: 31330093Free PMC Article
Leukemia: an overview for primary care.
Davis AS, Viera AJ, Mead MD
Am Fam Physician 2014 May 1;89(9):731-8. PMID: 24784336

Diagnosis

Olverembatinib: First Approval.
Dhillon S
Drugs 2022 Mar;82(4):469-475. doi: 10.1007/s40265-022-01680-9. PMID: 35195876
Chronic myeloid leukaemia.
Cortes J, Pavlovsky C, Saußele S
Lancet 2021 Nov 20;398(10314):1914-1926. Epub 2021 Aug 20 doi: 10.1016/S0140-6736(21)01204-6. PMID: 34425075
Chronic myeloid leukaemia.
Apperley JF
Lancet 2015 Apr 11;385(9976):1447-59. Epub 2014 Dec 5 doi: 10.1016/S0140-6736(13)62120-0. PMID: 25484026
Leukemia: an overview for primary care.
Davis AS, Viera AJ, Mead MD
Am Fam Physician 2014 May 1;89(9):731-8. PMID: 24784336
The leukemias.
Preisler HD
Dis Mon 1994 Oct;40(10):525-79. PMID: 7924833

Therapy

Chronic myeloid leukaemia.
Cortes J, Pavlovsky C, Saußele S
Lancet 2021 Nov 20;398(10314):1914-1926. Epub 2021 Aug 20 doi: 10.1016/S0140-6736(21)01204-6. PMID: 34425075
The argument for using imatinib in CML.
Claudiani S, Apperley JF
Hematology Am Soc Hematol Educ Program 2018 Nov 30;2018(1):161-167. doi: 10.1182/asheducation-2018.1.161. PMID: 30504305Free PMC Article
Dasatinib.
Lindauer M, Hochhaus A
Recent Results Cancer Res 2018;212:29-68. doi: 10.1007/978-3-319-91439-8_2. PMID: 30069624
Chronic myeloid leukemia: 2018 update on diagnosis, therapy and monitoring.
Jabbour E, Kantarjian H
Am J Hematol 2018 Mar;93(3):442-459. doi: 10.1002/ajh.25011. PMID: 29411417
The leukemias.
Preisler HD
Dis Mon 1994 Oct;40(10):525-79. PMID: 7924833

Prognosis

Is the Sokal or EUTOS long-term survival (ELTS) score a better predictor of responses and outcomes in persons with chronic myeloid leukemia receiving tyrosine-kinase inhibitors?
Zhang XS, Gale RP, Huang XJ, Jiang Q
Leukemia 2022 Feb;36(2):482-491. Epub 2021 Aug 19 doi: 10.1038/s41375-021-01387-y. PMID: 34413457Free PMC Article
Long-term outcomes with frontline nilotinib versus imatinib in newly diagnosed chronic myeloid leukemia in chronic phase: ENESTnd 10-year analysis.
Kantarjian HM, Hughes TP, Larson RA, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Boquimpani C, Pasquini R, Clark RE, Dubruille V, Flinn IW, Kyrcz-Krzemien S, Medras E, Zanichelli M, Bendit I, Cacciatore S, Titorenko K, Aimone P, Saglio G, Hochhaus A
Leukemia 2021 Feb;35(2):440-453. Epub 2021 Jan 7 doi: 10.1038/s41375-020-01111-2. PMID: 33414482Free PMC Article
Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.
Cortes JE, Kim DW, Pinilla-Ibarz J, le Coutre PD, Paquette R, Chuah C, Nicolini FE, Apperley JF, Khoury HJ, Talpaz M, DeAngelo DJ, Abruzzese E, Rea D, Baccarani M, Müller MC, Gambacorti-Passerini C, Lustgarten S, Rivera VM, Haluska FG, Guilhot F, Deininger MW, Hochhaus A, Hughes TP, Shah NP, Kantarjian HM
Blood 2018 Jul 26;132(4):393-404. Epub 2018 Mar 22 doi: 10.1182/blood-2016-09-739086. PMID: 29567798Free PMC Article
Leukemia: an overview for primary care.
Davis AS, Viera AJ, Mead MD
Am Fam Physician 2014 May 1;89(9):731-8. PMID: 24784336
The leukemias.
Preisler HD
Dis Mon 1994 Oct;40(10):525-79. PMID: 7924833

Clinical prediction guides

Ponatinib and blinatumomab for Philadelphia chromosome-positive acute lymphoblastic leukaemia: a US, single-centre, single-arm, phase 2 trial.
Jabbour E, Short NJ, Jain N, Huang X, Montalban-Bravo G, Banerjee P, Rezvani K, Jiang X, Kim KH, Kanagal-Shamanna R, Khoury JD, Patel K, Kadia TM, Daver N, Chien K, Alvarado Y, Garcia-Manero G, Issa GC, Haddad FG, Kwari M, Thankachan J, Delumpa R, Macaron W, Garris R, Konopleva M, Ravandi F, Kantarjian H
Lancet Haematol 2023 Jan;10(1):e24-e34. Epub 2022 Nov 16 doi: 10.1016/S2352-3026(22)00319-2. PMID: 36402146
Treatment of blast phase chronic myeloid leukaemia: A rare and challenging entity.
Copland M
Br J Haematol 2022 Dec;199(5):665-678. Epub 2022 Jul 22 doi: 10.1111/bjh.18370. PMID: 35866251Free PMC Article
The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML.
Vetrie D, Helgason GV, Copland M
Nat Rev Cancer 2020 Mar;20(3):158-173. Epub 2020 Jan 6 doi: 10.1038/s41568-019-0230-9. PMID: 31907378
Chronic myeloid leukemia with complex karyotypes: Prognosis and therapeutic approaches.
Asnafi AA, Deris Zayeri Z, Shahrabi S, Zibara K, Vosughi T
J Cell Physiol 2019 May;234(5):5798-5806. Epub 2018 Nov 14 doi: 10.1002/jcp.27505. PMID: 30430567
Chronic leukemia.
Greenberg EM, Probst A
Crit Care Nurs Clin North Am 2013 Dec;25(4):459-70, vi. doi: 10.1016/j.ccell.2013.09.003. PMID: 24267282

Recent systematic reviews

Chronic Myeloid Leukemia following Exposure to Radioactive Iodine (I131): A Systematic Review.
Ali Hailan YM, Al-Dubai HN, Yassin MA
Oncology 2023;101(6):362-368. Epub 2023 May 9 doi: 10.1159/000530463. PMID: 37231874
First-line imatinib vs second- and third-generation TKIs for chronic-phase CML: a systematic review and meta-analysis.
Vener C, Banzi R, Ambrogi F, Ferrero A, Saglio G, Pravettoni G, Sant M
Blood Adv 2020 Jun 23;4(12):2723-2735. doi: 10.1182/bloodadvances.2019001329. PMID: 32559295Free PMC Article
Has the time for first-line treatment with second generation tyrosine kinase inhibitors in patients with chronic myelogenous leukemia already come? Systematic review and meta-analysis.
Gurion R, Gafter-Gvili A, Vidal L, Leader A, Ram R, Shacham-Abulafia A, Paul M, Ben-Bassat I, Shpilberg O, Raanani P
Haematologica 2013 Jan;98(1):95-102. Epub 2012 Aug 8 doi: 10.3324/haematol.2012.063172. PMID: 22875617Free PMC Article
Exposure to benzene at work and the risk of leukemia: a systematic review and meta-analysis.
Khalade A, Jaakkola MS, Pukkala E, Jaakkola JJ
Environ Health 2010 Jun 28;9:31. doi: 10.1186/1476-069X-9-31. PMID: 20584305Free PMC Article
Chronic myelogenous leukemia and benzene exposure: a systematic review and meta-analysis of the case-control literature.
Lamm SH, Engel A, Joshi KP, Byrd DM 3rd, Chen R
Chem Biol Interact 2009 Dec 10;182(2-3):93-7. Epub 2009 Aug 18 doi: 10.1016/j.cbi.2009.08.010. PMID: 19695237

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