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Acute Retroviral Syndrome

MedGen UID:
907696
Concept ID:
C1868989
Disease or Syndrome
Synonym: Retroviral Syndrome, Acute

Definition

Early stage of HIV infection. Symptoms resemble INFLUENZA or INFECTIOUS MONONUCLEOSIS. [from MeSH]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAcute Retroviral Syndrome

Professional guidelines

PubMed

Graziani GM, Angel JB
J Int AIDS Soc 2015;18(1):20497. Epub 2015 Nov 9 doi: 10.7448/IAS.18.1.20497. PMID: 26561337Free PMC Article
Ambrosioni J, Nicolas D, Sued O, Agüero F, Manzardo C, Miro JM
Expert Rev Anti Infect Ther 2014 Jul;12(7):793-807. Epub 2014 May 7 doi: 10.1586/14787210.2014.913981. PMID: 24803105
Self WH
Emerg Med Clin North Am 2010 May;28(2):381-92, Table of Contents. doi: 10.1016/j.emc.2010.01.002. PMID: 20413020

Recent clinical studies

Etiology

Gabert R, Lama JR, Valdez R, Dasgupta S, Cabello R, Sanchez H, Leon M, Huamani JV, MacRae J, Montalban E, Pasalar S, Ignacio RB, Duerr A; (for the Sabes Study team)
AIDS 2023 Jun 1;37(7):1103-1108. Epub 2023 Mar 14 doi: 10.1097/QAD.0000000000003511. PMID: 36779502Free PMC Article
Hassan AS, Hare J, Gounder K, Nazziwa J, Karlson S, Olsson L, Streatfield C, Kamali A, Karita E, Kilembe W, Price MA, Borrow P, Björkman P, Kaleebu P, Allen S, Hunter E, Ndung'u T, Gilmour J, Rowland-Jones S, Esbjörnsson J, Sanders EJ
Clin Infect Dis 2021 Sep 7;73(5):832-841. doi: 10.1093/cid/ciab139. PMID: 33588436Free PMC Article
Ramos-E-Silva M, Secchin P, Trope B
Clin Dermatol 2020 Jan-Feb;38(1):52-62. Epub 2019 Nov 16 doi: 10.1016/j.clindermatol.2019.10.014. PMID: 32197749
Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group
Clin Infect Dis 2018 May 2;66(10):1540-1549. doi: 10.1093/cid/cix1063. PMID: 29228130Free PMC Article
Yerly S, Hirschel B
Expert Rev Anti Infect Ther 2012 Jan;10(1):31-41. doi: 10.1586/eri.11.154. PMID: 22149612

Diagnosis

Long B, Liang SY, Carius BM, Chavez S, Gottlieb M, Koyfman A, Brady WJ
Am J Emerg Med 2023 Mar;65:172-178. Epub 2023 Jan 5 doi: 10.1016/j.ajem.2023.01.007. PMID: 36640626Free PMC Article
De Clercq J, Rutsaert S, De Scheerder MA, Verhofstede C, Callens S, Vandekerckhove L
Acta Clin Belg 2022 Feb;77(1):168-176. Epub 2020 May 29 doi: 10.1080/17843286.2020.1770413. PMID: 32468932
Ramos-E-Silva M, Secchin P, Trope B
Clin Dermatol 2020 Jan-Feb;38(1):52-62. Epub 2019 Nov 16 doi: 10.1016/j.clindermatol.2019.10.014. PMID: 32197749
Yerly S, Hirschel B
Expert Rev Anti Infect Ther 2012 Jan;10(1):31-41. doi: 10.1586/eri.11.154. PMID: 22149612
Macneal RJ, Dinulos JG
Dermatol Clin 2006 Oct;24(4):431-8, v. doi: 10.1016/j.det.2006.06.001. PMID: 17010773

Therapy

Gabert R, Lama JR, Valdez R, Dasgupta S, Cabello R, Sanchez H, Leon M, Huamani JV, MacRae J, Montalban E, Pasalar S, Ignacio RB, Duerr A; (for the Sabes Study team)
AIDS 2023 Jun 1;37(7):1103-1108. Epub 2023 Mar 14 doi: 10.1097/QAD.0000000000003511. PMID: 36779502Free PMC Article
De Clercq J, Rutsaert S, De Scheerder MA, Verhofstede C, Callens S, Vandekerckhove L
Acta Clin Belg 2022 Feb;77(1):168-176. Epub 2020 May 29 doi: 10.1080/17843286.2020.1770413. PMID: 32468932
Crowell TA, Colby DJ, Pinyakorn S, Fletcher JLK, Kroon E, Schuetz A, Krebs SJ, Slike BM, Leyre L, Chomont N, Jagodzinski LL, Sereti I, Utay NS, Dewar R, Rerknimitr R, Chomchey N, Trichavaroj R, Valcour VG, Spudich S, Michael NL, Robb ML, Phanuphak N, Ananworanich J; RV254/SEARCH010 Study Group
Clin Infect Dis 2018 May 2;66(10):1540-1549. doi: 10.1093/cid/cix1063. PMID: 29228130Free PMC Article
Ambrosioni J, Nicolas D, Sued O, Agüero F, Manzardo C, Miro JM
Expert Rev Anti Infect Ther 2014 Jul;12(7):793-807. Epub 2014 May 7 doi: 10.1586/14787210.2014.913981. PMID: 24803105
Dorrucci M, Rezza G, Vlahov D, Pezzotti P, Sinicco A, Nicolosi A, Lazzarin A, Galai N, Gafà S, Pristerà R
AIDS 1995 Jun;9(6):597-604. doi: 10.1097/00002030-199506000-00011. PMID: 7662199

Prognosis

Akagi Y, Tanaka K, Mawatari M, Toda Y, Kumasaka T, Ueda A
Intern Med 2023;62(7):1089-1093. Epub 2023 Apr 1 doi: 10.2169/internalmedicine.9661-22. PMID: 37005296Free PMC Article
Rindler AE, Kusejko K, Kuster H, Neumann K, Leemann C, Zeeb M, Chaudron SE, Braun DL, Kouyos RD, Metzner KJ, Günthard HF
J Infect Dis 2022 Sep 21;226(6):1057-1068. doi: 10.1093/infdis/jiac100. PMID: 35299248
Socías ME, Sued O, Laufer N, Lázaro ME, Mingrone H, Pryluka D, Remondegui C, Figueroa MI, Cesar C, Gun A, Turk G, Bouzas MB, Kavasery R, Krolewiecki A, Pérez H, Salomón H, Cahn P; Grupo Argentino de Seroconversión Study Group
J Int AIDS Soc 2011 Aug 10;14:40. doi: 10.1186/1758-2652-14-40. PMID: 21831310Free PMC Article
Dorrucci M, Rezza G, Vlahov D, Pezzotti P, Sinicco A, Nicolosi A, Lazzarin A, Galai N, Gafà S, Pristerà R
AIDS 1995 Jun;9(6):597-604. doi: 10.1097/00002030-199506000-00011. PMID: 7662199
Clark SJ, Shaw GM
Semin Immunol 1993 Jun;5(3):149-55. doi: 10.1006/smim.1993.1018. PMID: 8347840

Clinical prediction guides

Erdmann N, Heath SL
Adv Exp Med Biol 2024;1448:269-274. doi: 10.1007/978-3-031-59815-9_18. PMID: 39117820
Rindler AE, Kusejko K, Kuster H, Neumann K, Leemann C, Zeeb M, Chaudron SE, Braun DL, Kouyos RD, Metzner KJ, Günthard HF
J Infect Dis 2022 Sep 21;226(6):1057-1068. doi: 10.1093/infdis/jiac100. PMID: 35299248
Sanders EJ, Price MA, Karita E, Kamali A, Kilembe W, Bekker LG, Lakhi S, Inambao M, Anzala O, Fast PE, Gilmour J, Powers KA
AIDS 2017 Nov 28;31(18):2541-2546. doi: 10.1097/QAD.0000000000001659. PMID: 29028659Free PMC Article
Braun DL, Kouyos R, Oberle C, Grube C, Joos B, Fellay J, McLaren PJ, Kuster H, Günthard HF
PLoS One 2014;9(12):e114111. Epub 2014 Dec 9 doi: 10.1371/journal.pone.0114111. PMID: 25490090Free PMC Article
Dorrucci M, Rezza G, Vlahov D, Pezzotti P, Sinicco A, Nicolosi A, Lazzarin A, Galai N, Gafà S, Pristerà R
AIDS 1995 Jun;9(6):597-604. doi: 10.1097/00002030-199506000-00011. PMID: 7662199

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