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Gonorrhea

MedGen UID:
9077
•Concept ID:
C0018081
•
Disease or Syndrome
Synonym: Neisseria gonorrhoeae Infection
SNOMED CT: GC - Gonococcus infection (15628003); Clap (15628003); GCI - Gonococcal infection (15628003); Gonorrhea (15628003); Gonococcal infection (15628003)
 
Monarch Initiative: MONDO:0004277
Orphanet: ORPHA100642

Definition

An infection that is caused by Gonococcus. [from NCI]

Professional guidelines

PubMed

Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Tuddenham S, Hamill MM, Ghanem KG
JAMA 2022 Jan 11;327(2):161-172. doi: 10.1001/jama.2021.23487. PMID: 35015033
Antimicrobial Resistance in Neisseria gonorrhoeae and Treatment of Gonorrhea.
Unemo M, Golparian D, Eyre DW
Methods Mol Biol 2019;1997:37-58. doi: 10.1007/978-1-4939-9496-0_3. PMID: 31119616
Conjunctivitis: a systematic review of diagnosis and treatment.
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article

Recent clinical studies

Etiology

Analysis and prediction of the incidence and prevalence trends of gonorrhea in China.
Chen X, Chen S, Li C, Shi L, Zhu Y, Yao Y
Hum Vaccin Immunother 2023 Aug;19(2):2256907. Epub 2023 Oct 9 doi: 10.1080/21645515.2023.2256907. PMID: 37807860Free PMC Article
An Update on Gonorrhea and Chlamydia.
Dutra K, Lazenby G
Obstet Gynecol Clin North Am 2023 Jun;50(2):299-310. Epub 2023 Apr 4 doi: 10.1016/j.ogc.2023.02.004. PMID: 37149311
Gonorrheal Diseases.
Perry M, Allison BA
Pediatr Rev 2018 Aug;39(8):427-429. doi: 10.1542/pir.2017-0120. PMID: 30068746
Epididymitis.
Taylor SN
Clin Infect Dis 2015 Dec 15;61 Suppl 8:S770-3. doi: 10.1093/cid/civ812. PMID: 26602616
Septic arthritis.
García-Arias M, Balsa A, Mola EM
Best Pract Res Clin Rheumatol 2011 Jun;25(3):407-21. doi: 10.1016/j.berh.2011.02.001. PMID: 22100289

Diagnosis

Antimicrobial Resistance in Gonorrhea.
Vitiello A, Ferrara F, Boccellino M, Ponzo A, Sabbatucci M, Zovi A
Microb Drug Resist 2024 Jul;30(7):297-303. Epub 2024 Apr 5 doi: 10.1089/mdr.2023.0259. PMID: 38579162
Ocular Gonorrhea.
Suyama Y, Akiyama R
N Engl J Med 2022 Apr 28;386(17):e46. Epub 2022 Apr 23 doi: 10.1056/NEJMicm2117893. PMID: 35452200
Gonorrheal Diseases.
Perry M, Allison BA
Pediatr Rev 2018 Aug;39(8):427-429. doi: 10.1542/pir.2017-0120. PMID: 30068746
Gonorrhea.
Morgan MK, Decker CF
Dis Mon 2016 Aug;62(8):260-8. Epub 2016 Apr 20 doi: 10.1016/j.disamonth.2016.03.009. PMID: 27107780
Gonorrhea: new challenges.
Skerlev M, Čulav-Košćak I
Clin Dermatol 2014 Mar-Apr;32(2):275-81. doi: 10.1016/j.clindermatol.2013.08.010. PMID: 24559563

Therapy

Epidemiology, Treatments, and Vaccine Development for Antimicrobial-Resistant Neisseria gonorrhoeae: Current Strategies and Future Directions.
Lin EY, Adamson PC, Klausner JD
Drugs 2021 Jul;81(10):1153-1169. Epub 2021 Jun 7 doi: 10.1007/s40265-021-01530-0. PMID: 34097283Free PMC Article
Clinical update.
Haddow L, Herbert S
Sex Transm Infect 2015 Mar;91(2):150. doi: 10.1136/sextrans-2014-051963. PMID: 25698792
Azithromycin in gonorrhoea.
Waugh MA
Int J STD AIDS 1996;7 Suppl 1:2-4. doi: 10.1258/0956462961917212. PMID: 8652723
Ofloxacin.
Tunkel AR, Scheld WM
Infect Control Hosp Epidemiol 1991 Sep;12(9):549-57. doi: 10.1086/646408. PMID: 1940278
Ceftriaxone: a third-generation cephalosporin.
Nahata MC, Barson WJ
Drug Intell Clin Pharm 1985 Dec;19(12):900-6. doi: 10.1177/106002808501901203. PMID: 3910386

Prognosis

Analysis and prediction of the incidence and prevalence trends of gonorrhea in China.
Chen X, Chen S, Li C, Shi L, Zhu Y, Yao Y
Hum Vaccin Immunother 2023 Aug;19(2):2256907. Epub 2023 Oct 9 doi: 10.1080/21645515.2023.2256907. PMID: 37807860Free PMC Article
Sexually Transmitted Infections Among US Women and Men: Prevalence and Incidence Estimates, 2018.
Kreisel KM, Spicknall IH, Gargano JW, Lewis FMT, Lewis RM, Markowitz LE, Roberts H, Johnson AS, Song R, St Cyr SB, Weston EJ, Torrone EA, Weinstock HS
Sex Transm Dis 2021 Apr 1;48(4):208-214. doi: 10.1097/OLQ.0000000000001355. PMID: 33492089Free PMC Article
Gonorrhea: new challenges.
Skerlev M, Čulav-Košćak I
Clin Dermatol 2014 Mar-Apr;32(2):275-81. doi: 10.1016/j.clindermatol.2013.08.010. PMID: 24559563
Septic sacroiliitis.
Osman AA, Govender S
Clin Orthop Relat Res 1995 Apr;(313):214-9. PMID: 7641483
The tiniest newborns.
Strong C
Hastings Cent Rep 1983 Feb;13(1):14-9. PMID: 6841060

Clinical prediction guides

Analysis and prediction of the incidence and prevalence trends of gonorrhea in China.
Chen X, Chen S, Li C, Shi L, Zhu Y, Yao Y
Hum Vaccin Immunother 2023 Aug;19(2):2256907. Epub 2023 Oct 9 doi: 10.1080/21645515.2023.2256907. PMID: 37807860Free PMC Article
Immune responses to Neisseria gonorrhoeae and implications for vaccine development.
Belcher T, Rollier CS, Dold C, Ross JDC, MacLennan CA
Front Immunol 2023;14:1248613. Epub 2023 Aug 17 doi: 10.3389/fimmu.2023.1248613. PMID: 37662926Free PMC Article
Recent Progress Towards a Gonococcal Vaccine.
Maurakis SA, Cornelissen CN
Front Cell Infect Microbiol 2022;12:881392. Epub 2022 Apr 11 doi: 10.3389/fcimb.2022.881392. PMID: 35480233Free PMC Article
Gonorrhea.
Ehret JM, Knapp JS
Clin Lab Med 1989 Sep;9(3):445-80. PMID: 2507216
Spectinomycin.
Holloway WJ
Med Clin North Am 1982 Jan;66(1):169-73. PMID: 6460907

Recent systematic reviews

Long-Acting Reversible Contraception, Condom Use, and Sexually Transmitted Infections: A Systematic Review and Meta-analysis.
Steiner RJ, Pampati S, Kortsmit KM, Liddon N, Swartzendruber A, Pazol K
Am J Prev Med 2021 Nov;61(5):750-760. Epub 2021 Sep 16 doi: 10.1016/j.amepre.2021.04.032. PMID: 34686301Free PMC Article
The vaginal microbiota and its association with human papillomavirus, Chlamydia trachomatis, Neisseria gonorrhoeae and Mycoplasma genitalium infections: a systematic review and meta-analysis.
Tamarelle J, Thiébaut ACM, de Barbeyrac B, Bébéar C, Ravel J, Delarocque-Astagneau E
Clin Microbiol Infect 2019 Jan;25(1):35-47. Epub 2018 May 3 doi: 10.1016/j.cmi.2018.04.019. PMID: 29729331Free PMC Article
Conjunctivitis: a systematic review of diagnosis and treatment.
Azari AA, Barney NP
JAMA 2013 Oct 23;310(16):1721-9. doi: 10.1001/jama.2013.280318. PMID: 24150468Free PMC Article
Bacterial conjunctivitis.
Epling J
BMJ Clin Evid 2012 Feb 20;2012 PMID: 22348418Free PMC Article
Bacterial conjunctivitis.
Epling J
BMJ Clin Evid 2010 Mar 15;2010 PMID: 21718563Free PMC Article

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