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Choriocarcinoma Combined with Other Germ Cell Elements

MedGen UID:
90800
Concept ID:
C0334527
Neoplastic Process
Synonyms: Choriocarcinoma combined with embryonal carcinoma; Choriocarcinoma combined with germ cell elements; Choriocarcinoma combined with other germ cell elements
SNOMED CT: Choriocarcinoma combined with germ cell elements (8734000); Choriocarcinoma combined with other germ cell elements (8734000); Choriocarcinoma combined with embryonal carcinoma (8734000)

Definition

A malignant mixed germ cell tumor characterized by the presence of a choriocarcinomatous component admixed with another germ cell component (e.g. embryonal carcinoma, teratoma, or seminoma). [from NCI]

Professional guidelines

Recent clinical studies

Etiology

Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Moran CA, Suster S, Koss MN
Cancer 1997 Aug 15;80(4):699-707. PMID: 9264353
Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, Seto T
J Neurosurg 1997 Mar;86(3):446-55. doi: 10.3171/jns.1997.86.3.0446. PMID: 9046301
Little JS Jr, Foster RS, Ulbright TM, Donohue JP
J Urol 1994 Oct;152(4):1144-9. doi: 10.1016/s0022-5347(17)32524-7. PMID: 8072083
Ulbright TM
Am J Surg Pathol 1993 Nov;17(11):1075-91. doi: 10.1097/00000478-199311000-00001. PMID: 8214253

Diagnosis

Xiao GQ, Li F, Unger PD, Katerji H, Yang Q, McMahon L, Burstein DE
Mod Pathol 2016 Jun;29(6):591-8. Epub 2016 Feb 26 doi: 10.1038/modpathol.2016.46. PMID: 26916077
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Moran CA, Suster S, Koss MN
Cancer 1997 Aug 15;80(4):699-707. PMID: 9264353
Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, Seto T
J Neurosurg 1997 Mar;86(3):446-55. doi: 10.3171/jns.1997.86.3.0446. PMID: 9046301
Hanai J, Lin M, Wada A, Ishiguro S, Miki T, Sakaguchi H, Kanda H
Histol Histopathol 1992 Oct;7(4):533-41. PMID: 1333851

Therapy

Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, Seto T
J Neurosurg 1997 Mar;86(3):446-55. doi: 10.3171/jns.1997.86.3.0446. PMID: 9046301
Blake KI, Gerrard MP
Med Pediatr Oncol 1993;21(4):299-300. doi: 10.1002/mpo.2950210413. PMID: 7682284

Prognosis

Xiao GQ, Li F, Unger PD, Katerji H, Yang Q, McMahon L, Burstein DE
Mod Pathol 2016 Jun;29(6):591-8. Epub 2016 Feb 26 doi: 10.1038/modpathol.2016.46. PMID: 26916077
Ulbright TM
Mod Pathol 2005 Feb;18 Suppl 2:S61-79. doi: 10.1038/modpathol.3800310. PMID: 15761467
Moran CA, Suster S, Koss MN
Cancer 1997 Aug 15;80(4):699-707. PMID: 9264353
Matsutani M, Sano K, Takakura K, Fujimaki T, Nakamura O, Funata N, Seto T
J Neurosurg 1997 Mar;86(3):446-55. doi: 10.3171/jns.1997.86.3.0446. PMID: 9046301
Bosl GJ, Geller N, Cirrincione C, Hajdu SI, Whitmore W Jr, Nisselbaum J, Vugrin D, Golbey RB
Cancer 1983 Jun 1;51(11):2121-5. doi: 10.1002/1097-0142(19830601)51:11<2121::aid-cncr2820511128>3.0.co;2-2. PMID: 6188528

Clinical prediction guides

Xiao GQ, Li F, Unger PD, Katerji H, Yang Q, McMahon L, Burstein DE
Mod Pathol 2016 Jun;29(6):591-8. Epub 2016 Feb 26 doi: 10.1038/modpathol.2016.46. PMID: 26916077
Moran CA, Suster S, Koss MN
Cancer 1997 Aug 15;80(4):699-707. PMID: 9264353
Little JS Jr, Foster RS, Ulbright TM, Donohue JP
J Urol 1994 Oct;152(4):1144-9. doi: 10.1016/s0022-5347(17)32524-7. PMID: 8072083
Hanai J, Lin M, Wada A, Ishiguro S, Miki T, Sakaguchi H, Kanda H
Histol Histopathol 1992 Oct;7(4):533-41. PMID: 1333851
Knapp RH, Hurt RD, Payne WS, Farrow GM, Lewis BD, Hahn RG, Muhm JR, Earle JD
J Thorac Cardiovasc Surg 1985 Jan;89(1):82-9. PMID: 2981374

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