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Astroblastoma

MedGen UID:
90811
Concept ID:
C0334587
Neoplastic Process
Synonym: Cerebral astroblastoma
SNOMED CT: Astroblastoma (48952003)
Modes of inheritance:
Not genetically inherited
MedGen UID:
988794
Concept ID:
CN307044
Finding
Source: Orphanet
clinical entity without genetic inheritance.
 
Monarch Initiative: MONDO:0016707
Orphanet: ORPHA251679

Definition

A very rare glial neoplasm of the central nervous system, most often with an intra-axial peripheral supratentorial location in one hemisphere of the frontal or parietal lobes and usually presenting in infants and young adults with symptoms of vomiting, loss of consciousness, epileptic seizures and headaches. [from ORDO]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVAstroblastoma
Follow this link to review classifications for Astroblastoma in Orphanet.

Professional guidelines

PubMed

Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA
Neuro Oncol 2022 Nov 2;24(11):1964-1975. doi: 10.1093/neuonc/noac096. PMID: 35397478Free PMC Article
Jeon C, Kim B, Choi JW
J Neurosurg Pediatr 2022 May 1;29(5):513-519. Epub 2022 Feb 18 doi: 10.3171/2022.1.PEDS21389. PMID: 35180693
Merfeld EC, Dahiya S, Perkins SM
CNS Oncol 2018 Apr;7(2):CNS13. Epub 2018 Apr 30 doi: 10.2217/cns-2017-0038. PMID: 29708401Free PMC Article

Recent clinical studies

Etiology

Köy Y, Tihan T
Indian J Pathol Microbiol 2022 May;65(Supplement):S33-S41. doi: 10.4103/ijpm.ijpm_1019_21. PMID: 35562132
Jeon C, Kim B, Choi JW
J Neurosurg Pediatr 2022 May 1;29(5):513-519. Epub 2022 Feb 18 doi: 10.3171/2022.1.PEDS21389. PMID: 35180693
Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Teleanu DM, Ilieşiu A, Bălaşa AF, Teleanu RI, Bogaciu NŞ
Rom J Morphol Embryol 2018;59(4):1239-1245. PMID: 30845307
Caroli E, Salvati M, Esposito V, Orlando ER, Giangaspero F
Acta Neurochir (Wien) 2004 Jun;146(6):629-33. Epub 2004 Apr 13 doi: 10.1007/s00701-004-0230-7. PMID: 15168232

Diagnosis

Pratt D, Abdullaev Z, Papanicolau-Sengos A, Ketchum C, Panneer Selvam P, Chung HJ, Lee I, Raffeld M, Gilbert MR, Armstrong TS, Pytel P, Borys E, Klonoski JM, McCord M, Horbinski C, Brat D, Perry A, Solomon D, Eberhart C, Giannini C, Quezado M, Aldape K
Acta Neuropathol 2022 Mar;143(3):403-414. Epub 2022 Feb 1 doi: 10.1007/s00401-022-02404-9. PMID: 35103816Free PMC Article
Sarper B, Yaprak Bayrak B, Halis H, Alparslan B, Yeni Bayraktar H
Balkan Med J 2020 Jun 1;37(4):224-225. Epub 2020 Mar 26 doi: 10.4274/balkanmedj.galenos.2020.2019.11.39. PMID: 32212579Free PMC Article
Cunningham DA, Lowe LH, Shao L, Acosta NR
Pediatr Radiol 2016 Aug;46(9):1301-8. Epub 2016 Apr 5 doi: 10.1007/s00247-016-3607-x. PMID: 27048363
Soffietti R, Rudà R, Reardon D
Handb Clin Neurol 2016;134:399-415. doi: 10.1016/B978-0-12-802997-8.00024-4. PMID: 26948368
Caroli E, Salvati M, Esposito V, Orlando ER, Giangaspero F
Acta Neurochir (Wien) 2004 Jun;146(6):629-33. Epub 2004 Apr 13 doi: 10.1007/s00701-004-0230-7. PMID: 15168232

Therapy

Rosenberg T, Yeo KK, Mauguen A, Alexandrescu S, Prabhu SP, Tsai JW, Malinowski S, Joshirao M, Parikh K, Farouk Sait S, Rosenblum MK, Benhamida JK, Michaiel G, Tran HN, Dahiya S, Kachurak K, Friedman GK, Krystal JI, Huang MA, Margol AS, Wright KD, Aguilera D, MacDonald TJ, Chi SN, Karajannis MA
Neuro Oncol 2022 Nov 2;24(11):1964-1975. doi: 10.1093/neuonc/noac096. PMID: 35397478Free PMC Article
Andrews LJ, Thornton ZA, Saincher SS, Yao IY, Dawson S, McGuinness LA, Jones HE, Jefferies S, Short SC, Cheng HY, McAleenan A, Higgins JPT, Kurian KM
Neuro Oncol 2022 Apr 1;24(4):528-540. doi: 10.1093/neuonc/noab247. PMID: 34718782Free PMC Article
Sarper B, Yaprak Bayrak B, Halis H, Alparslan B, Yeni Bayraktar H
Balkan Med J 2020 Jun 1;37(4):224-225. Epub 2020 Mar 26 doi: 10.4274/balkanmedj.galenos.2020.2019.11.39. PMID: 32212579Free PMC Article
Sarmiento JM, Venteicher AS, Patil CG
Cochrane Database Syst Rev 2015 Jun 29;6(6):CD009229. doi: 10.1002/14651858.CD009229.pub2. PMID: 26118544Free PMC Article
Unal E, Koksal Y, Vajtai I, Toy H, Kocaogullar Y, Paksoy Y
Childs Nerv Syst 2008 Feb;24(2):165-8. Epub 2007 Jul 26 doi: 10.1007/s00381-007-0424-4. PMID: 17653728

Prognosis

Sun D, Liu J, Xiao L, Guan H
Clin Neuropathol 2023 Jan-Feb;42(1):30-39. doi: 10.5414/NP301497. PMID: 36366964
Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Barakat MI, Ammar MG, Salama HM, Abuhashem S
Turk Neurosurg 2016;26(5):790-4. doi: 10.5137/1019-5149.JTN.9408-13.2. PMID: 27349390
Soffietti R, Rudà R, Reardon D
Handb Clin Neurol 2016;134:399-415. doi: 10.1016/B978-0-12-802997-8.00024-4. PMID: 26948368
Caroli E, Salvati M, Esposito V, Orlando ER, Giangaspero F
Acta Neurochir (Wien) 2004 Jun;146(6):629-33. Epub 2004 Apr 13 doi: 10.1007/s00701-004-0230-7. PMID: 15168232

Clinical prediction guides

Sun D, Liu J, Xiao L, Guan H
Clin Neuropathol 2023 Jan-Feb;42(1):30-39. doi: 10.5414/NP301497. PMID: 36366964
Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Zschernack V, Jünger ST, Mynarek M, Rutkowski S, Garre ML, Ebinger M, Neu M, Faber J, Erdlenbruch B, Claviez A, Bielack S, Brozou T, Frühwald MC, Dörner E, Dreschmann V, Stock A, Solymosi L, Hench J, Frank S, Vokuhl C, Waha A, Andreiuolo F, Pietsch T
Acta Neuropathol 2021 Mar;141(3):455-466. Epub 2021 Jan 22 doi: 10.1007/s00401-020-02260-5. PMID: 33481105Free PMC Article
Yapıcıer Ö, Demir MK, Özdamarlar U, Kılıç D, Akakın A, Kılıç T
Childs Nerv Syst 2019 Jul;35(7):1251-1255. Epub 2019 Mar 12 doi: 10.1007/s00381-019-04113-3. PMID: 30859299
Janz C, Buhl R
Clin Neurol Neurosurg 2014 Oct;125:114-24. Epub 2014 Jul 21 doi: 10.1016/j.clineuro.2014.07.013. PMID: 25108699

Recent systematic reviews

Kurokawa R, Baba A, Kurokawa M, Ota Y, Hassan O, Capizzano A, Kim J, Johnson T, Srinivasan A, Moritani T
J Neuroimaging 2022 Mar;32(2):201-212. Epub 2021 Nov 23 doi: 10.1111/jon.12948. PMID: 34816541
Andrews LJ, Thornton ZA, Saincher SS, Yao IY, Dawson S, McGuinness LA, Jones HE, Jefferies S, Short SC, Cheng HY, McAleenan A, Higgins JPT, Kurian KM
Neuro Oncol 2022 Apr 1;24(4):528-540. doi: 10.1093/neuonc/noab247. PMID: 34718782Free PMC Article
Chen W, Soon YY, Pratiseyo PD, Sutanto R, Hendriansyah L, Kuick CH, Chang KTE, Tan CL
Brain Tumor Pathol 2020 Oct;37(4):145-153. Epub 2020 Jun 29 doi: 10.1007/s10014-020-00372-0. PMID: 32601775
Cunningham DA, Lowe LH, Shao L, Acosta NR
Pediatr Radiol 2016 Aug;46(9):1301-8. Epub 2016 Apr 5 doi: 10.1007/s00247-016-3607-x. PMID: 27048363
Sarmiento JM, Venteicher AS, Patil CG
Cochrane Database Syst Rev 2015 Jun 29;6(6):CD009229. doi: 10.1002/14651858.CD009229.pub2. PMID: 26118544Free PMC Article

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