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Gonococcal conjunctivitis neonatorum

MedGen UID:
90938
Concept ID:
C0339166
Disease or Syndrome
Synonym: Ophthalmia Neonatorum
SNOMED CT: Opthalmia neonatorum caused by Neisseria (28438004); Gonococcal conjunctivitis neonatorum (28438004); Gonococcal ophthalmia neonatorum (28438004); Neonatal gonococcal conjunctivitis (28438004)

Definition

Inflammation of the conjunctiva in a newborn due to Neisseria gonorrhoeae which was acquired during labor and delivery. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVGonococcal conjunctivitis neonatorum
Follow this link to review classifications for Gonococcal conjunctivitis neonatorum in Orphanet.

Professional guidelines

PubMed

Burn H, Puri L, Roshan A, Singh SK, Burton MJ
Ophthalmic Epidemiol 2020 Jun;27(3):165-176. Epub 2019 Dec 16 doi: 10.1080/09286586.2019.1702217. PMID: 31842661Free PMC Article
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Zar HJ
Paediatr Drugs 2005;7(2):103-10. doi: 10.2165/00148581-200507020-00003. PMID: 15871630

Recent clinical studies

Etiology

Bibb LA, Htet KZ, Waldman CW, Sloan SB
Clin Dermatol 2024 Jan-Feb;42(1):25-37. Epub 2023 Aug 13 doi: 10.1016/j.clindermatol.2023.08.011. PMID: 37582453
Comunián-Carrasco G, Peña-Martí GE, Martí-Carvajal AJ
Cochrane Database Syst Rev 2018 Feb 21;2(2):CD011167. doi: 10.1002/14651858.CD011167.pub2. PMID: 29465747Free PMC Article
Zuppa AA, D'Andrea V, Catenazzi P, Scorrano A, Romagnoli C
J Matern Fetal Neonatal Med 2011 Jun;24(6):769-73. doi: 10.3109/14767058.2010.531326. PMID: 21534852
Gul SS, Jamal M, Khan N
J Coll Physicians Surg Pak 2010 Sep;20(9):595-8. PMID: 20810051
Spence MR
Clin Obstet Gynecol 1983 Mar;26(1):111-24. doi: 10.1097/00003081-198303000-00016. PMID: 6404578

Diagnosis

Ni J, Chan K, Marpuri I, Eisenberg J
Pediatr Ann 2022 May;51(5):e206-e208. Epub 2022 May 1 doi: 10.3928/19382359-20220314-04. PMID: 35575542
Tan AK
N Engl J Med 2019 Jan 10;380(2):e2. doi: 10.1056/NEJMicm1808613. PMID: 30625059
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Schneider G
Can Med Assoc J 1984 Aug 1;131(3):193-6. PMID: 6378348Free PMC Article
Spence MR
Clin Obstet Gynecol 1983 Mar;26(1):111-24. doi: 10.1097/00003081-198303000-00016. PMID: 6404578

Therapy

Barberá MJ, Serra-Pladevall J
Enferm Infecc Microbiol Clin (Engl Ed) 2019 Aug-Sep;37(7):458-466. Epub 2019 Feb 4 doi: 10.1016/j.eimc.2018.12.008. PMID: 30732970
Grzybowski A, Kanclerz P, Myers WG
Curr Opin Ophthalmol 2018 Jan;29(1):19-32. doi: 10.1097/ICU.0000000000000437. PMID: 28984794
Schneider G
Can Med Assoc J 1984 Aug 1;131(3):193-6. PMID: 6378348Free PMC Article
Spence MR
Clin Obstet Gynecol 1983 Mar;26(1):111-24. doi: 10.1097/00003081-198303000-00016. PMID: 6404578
Friendly DS
Pediatr Clin North Am 1983 Dec;30(6):1033-42. doi: 10.1016/s0031-3955(16)34500-x. PMID: 6359042

Prognosis

Yang K, Babalola CM, Mussa A, Ryan R, Wynn A, Simon S, Bame B, Morroni C, Klausner JD
Int J STD AIDS 2023 Oct;34(12):860-868. Epub 2023 Jun 20 doi: 10.1177/09564624231173028. PMID: 37338101
Muthiah S, Radhakrishnan N
Indian J Pediatr 2017 Dec;84(12):945-952. Epub 2017 Jul 14 doi: 10.1007/s12098-017-2409-y. PMID: 28707045
Quirke M, Cullinane A
Int J Infect Dis 2008 Jul;12(4):371-3. Epub 2008 Feb 21 doi: 10.1016/j.ijid.2007.09.013. PMID: 18093859
Blanchard TJ, Mabey DC
Br J Clin Pract 1994 Jul-Aug;48(4):201-5. PMID: 7917800
O'Hara MA
Pediatr Clin North Am 1993 Aug;40(4):715-25. PMID: 8345961

Clinical prediction guides

Harman LE, Margo CE
Cornea 2023 Dec 1;42(12):1601-1604. Epub 2023 Jul 6 doi: 10.1097/ICO.0000000000003332. PMID: 37410593
Yang K, Babalola CM, Mussa A, Ryan R, Wynn A, Simon S, Bame B, Morroni C, Klausner JD
Int J STD AIDS 2023 Oct;34(12):860-868. Epub 2023 Jun 20 doi: 10.1177/09564624231173028. PMID: 37338101
McAnena L, Knowles SJ, Curry A, Cassidy L
Eye (Lond) 2015 Jul;29(7):875-80. Epub 2015 Apr 24 doi: 10.1038/eye.2015.57. PMID: 25907207Free PMC Article
Gul SS, Jamal M, Khan N
J Coll Physicians Surg Pak 2010 Sep;20(9):595-8. PMID: 20810051
Amini E, Ghasemi M, Daneshjou K
Med Sci Monit 2008 Feb;14(2):CR90-96. PMID: 18227767

Recent systematic reviews

Vallely LM, Egli-Gany D, Wand H, Pomat WS, Homer CSE, Guy R, Silver B, Rumbold AR, Kaldor JM, Vallely AJ, Low N
Sex Transm Infect 2021 Mar;97(2):104-111. Epub 2021 Jan 12 doi: 10.1136/sextrans-2020-054653. PMID: 33436505Free PMC Article
Kapoor VS, Evans JR, Vedula SS
Cochrane Database Syst Rev 2020 Sep 21;9(9):CD001862. doi: 10.1002/14651858.CD001862.pub4. PMID: 32959365Free PMC Article
Comunián-Carrasco G, Peña-Martí GE, Martí-Carvajal AJ
Cochrane Database Syst Rev 2018 Feb 21;2(2):CD011167. doi: 10.1002/14651858.CD011167.pub2. PMID: 29465747Free PMC Article
Darling EK, McDonald H
J Midwifery Womens Health 2010 Jul-Aug;55(4):319-27. doi: 10.1016/j.jmwh.2009.09.003. PMID: 20630358
Brocklehurst P
Cochrane Database Syst Rev 2002;(2):CD000098. doi: 10.1002/14651858.CD000098. PMID: 12076381

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