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Fungal esophagitis

MedGen UID:
90960
•Concept ID:
C0341109
•
Disease or Syndrome
Synonyms: Fungal Esophagitis; fungal esophagitis
SNOMED CT: Fungal esophagitis (235602008)
 
Monarch Initiative: MONDO:0001649

Definition

Infection of the esophagus caused by fungi, most often candida albicans and candida tropicalis. It usually affects patients with immunodeficiency disorders or diabetes mellitus. Symptoms include dysphagia and pain on swallowing. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVFungal esophagitis

Professional guidelines

PubMed

Esophagitis, treatment outcomes, and long-term follow-up in children with esophageal atresia.
Bashir A, Krasaelap A, Lal DR, Gourlay DM, Pan AY, Jan N, McCord S, Lerner DG
J Pediatr Gastroenterol Nutr 2024 Dec;79(6):1116-1123. Epub 2024 Oct 16 doi: 10.1002/jpn3.12386. PMID: 39415542
Management of HIV-associated esophageal disease.
Belitsos PC
AIDS Clin Care 1995 Mar;7(3):19-22. PMID: 11362191

Recent clinical studies

Etiology

Esophagitis, treatment outcomes, and long-term follow-up in children with esophageal atresia.
Bashir A, Krasaelap A, Lal DR, Gourlay DM, Pan AY, Jan N, McCord S, Lerner DG
J Pediatr Gastroenterol Nutr 2024 Dec;79(6):1116-1123. Epub 2024 Oct 16 doi: 10.1002/jpn3.12386. PMID: 39415542
Prevalence, Predictive Factors, and Clinical Manifestations of Fungal Esophagitis in Children.
Correia AA, Weber MA, Krishnan U
J Pediatr Gastroenterol Nutr 2023 Nov 1;77(5):610-617. Epub 2023 Sep 6 doi: 10.1097/MPG.0000000000003927. PMID: 37608450
Fungal Esophagitis in a Child with Insulin Dependent Diabetes Mellitus.
Saeed A, Assiri A, Zaidi Z, Alsheikh A
J Coll Physicians Surg Pak 2016 Aug;26(8):712-3. PMID: 27539771
Clinical and endoscopic characteristics of drug-induced esophagitis.
Kim SH, Jeong JB, Kim JW, Koh SJ, Kim BG, Lee KL, Chang MS, Im JP, Kang HW, Shin CM
World J Gastroenterol 2014 Aug 21;20(31):10994-9. doi: 10.3748/wjg.v20.i31.10994. PMID: 25152603Free PMC Article
Comparison of single-dose and 7-day fluconazole treatment of fungal esophagitis in alcoholic liver disease.
Péter Z, Horváth Z, Makara M, Telegdy L, Zala J, Zágoni T
Z Gastroenterol 1996 Jun;34(6):361-4. PMID: 8767824

Diagnosis

Elevated FAPI Activity in Ulcerative Fungal Esophagitis.
Xie Y, Tang W, Liu H, Chen Y
Clin Nucl Med 2023 Dec 1;48(12):1099-1101. Epub 2023 Oct 23 doi: 10.1097/RLU.0000000000004880. PMID: 37883121
Gastrointestinal manifestations of leukemia.
Ebert EC, Hagspiel KD
J Gastroenterol Hepatol 2012 Mar;27(3):458-63. doi: 10.1111/j.1440-1746.2011.06908.x. PMID: 21913980
Gastrointestinal complications in renal transplant recipients.
Ponticelli C, Passerini P
Transpl Int 2005 Jun;18(6):643-50. doi: 10.1111/j.1432-2277.2005.00134.x. PMID: 15910287
Drug-induced dysphagia.
Stoschus B, Allescher HD
Dysphagia 1993;8(2):154-9. doi: 10.1007/BF02266997. PMID: 8467724
Fungal esophagitis in children.
Young C, Chang MH, Chen JM
Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi 1993 Nov-Dec;34(6):436-42. PMID: 8296555

Therapy

Fungal Esophagitis in a Child with Insulin Dependent Diabetes Mellitus.
Saeed A, Assiri A, Zaidi Z, Alsheikh A
J Coll Physicians Surg Pak 2016 Aug;26(8):712-3. PMID: 27539771
Clinical and endoscopic characteristics of drug-induced esophagitis.
Kim SH, Jeong JB, Kim JW, Koh SJ, Kim BG, Lee KL, Chang MS, Im JP, Kang HW, Shin CM
World J Gastroenterol 2014 Aug 21;20(31):10994-9. doi: 10.3748/wjg.v20.i31.10994. PMID: 25152603Free PMC Article
Gastrointestinal complications in renal transplant recipients.
Ponticelli C, Passerini P
Transpl Int 2005 Jun;18(6):643-50. doi: 10.1111/j.1432-2277.2005.00134.x. PMID: 15910287
Comparison of single-dose and 7-day fluconazole treatment of fungal esophagitis in alcoholic liver disease.
Péter Z, Horváth Z, Makara M, Telegdy L, Zala J, Zágoni T
Z Gastroenterol 1996 Jun;34(6):361-4. PMID: 8767824
Management of HIV-associated esophageal disease.
Belitsos PC
AIDS Clin Care 1995 Mar;7(3):19-22. PMID: 11362191

Prognosis

Esophagitis, treatment outcomes, and long-term follow-up in children with esophageal atresia.
Bashir A, Krasaelap A, Lal DR, Gourlay DM, Pan AY, Jan N, McCord S, Lerner DG
J Pediatr Gastroenterol Nutr 2024 Dec;79(6):1116-1123. Epub 2024 Oct 16 doi: 10.1002/jpn3.12386. PMID: 39415542
Prevalence, Predictive Factors, and Clinical Manifestations of Fungal Esophagitis in Children.
Correia AA, Weber MA, Krishnan U
J Pediatr Gastroenterol Nutr 2023 Nov 1;77(5):610-617. Epub 2023 Sep 6 doi: 10.1097/MPG.0000000000003927. PMID: 37608450
The IL-20RB receptor and the IL-20 signaling pathway in regulating host defense in oral mucosal candidiasis.
Beute JE, Kim AY, Park JJ, Yang A, Torres-Shafer K, Mullins DW, Sundstrom P
Front Cell Infect Microbiol 2022;12:979701. Epub 2022 Sep 26 doi: 10.3389/fcimb.2022.979701. PMID: 36225230Free PMC Article
Clinical and endoscopic characteristics of drug-induced esophagitis.
Kim SH, Jeong JB, Kim JW, Koh SJ, Kim BG, Lee KL, Chang MS, Im JP, Kang HW, Shin CM
World J Gastroenterol 2014 Aug 21;20(31):10994-9. doi: 10.3748/wjg.v20.i31.10994. PMID: 25152603Free PMC Article
Serial study of C-reactive protein during fungal esophagitis and enterocolitis.
Kostiala I, Kostiala AA, Elonen E
Infection 1987 Nov-Dec;15(6):417-21. doi: 10.1007/BF01647219. PMID: 3436672

Clinical prediction guides

Prevalence, Predictive Factors, and Clinical Manifestations of Fungal Esophagitis in Children.
Correia AA, Weber MA, Krishnan U
J Pediatr Gastroenterol Nutr 2023 Nov 1;77(5):610-617. Epub 2023 Sep 6 doi: 10.1097/MPG.0000000000003927. PMID: 37608450
An unusual presentation of diabetic ketoacidosis associated with ascariasis and fungal esophagitis: A case report.
Alduraibi RK, Elzaki EM, Alammari A
Medicine (Baltimore) 2022 Nov 25;101(47):e32015. doi: 10.1097/MD.0000000000032015. PMID: 36451505Free PMC Article
Clinical and endoscopic characteristics of drug-induced esophagitis.
Kim SH, Jeong JB, Kim JW, Koh SJ, Kim BG, Lee KL, Chang MS, Im JP, Kang HW, Shin CM
World J Gastroenterol 2014 Aug 21;20(31):10994-9. doi: 10.3748/wjg.v20.i31.10994. PMID: 25152603Free PMC Article
Clinical, endoscopic, immunologic, and therapeutic aspects of oropharyngeal and esophageal candidiasis in HIV-infected patients: a survey of 114 cases.
López-Dupla M, Mora Sanz P, Pintado García V, Valencia Ortega E, Uriol PL, Khamashta MA, Aguado AG
Am J Gastroenterol 1992 Dec;87(12):1771-6. PMID: 1449139

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