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Cyst of parathyroid

MedGen UID:
90980
•Concept ID:
C0342347
•
Anatomical Abnormality
Synonyms: Cyst of Parathyroid; Cyst of the Parathyroid; Parathyroid cyst; Parathyroid Cyst
SNOMED CT: Cyst of parathyroid (190459003); Parathyroid cyst (190459003)

Definition

An epithelium-lined, fluid-filled cyst containing parathyroid hormone that is usually located in an inferior parathyroid gland, but may be found in other locations in the neck or mediastinum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCyst of parathyroid

Professional guidelines

PubMed

The diagnosis and management of hypercalcaemia.
Minisola S, Pepe J, Piemonte S, Cipriani C
BMJ 2015 Jun 2;350:h2723. doi: 10.1136/bmj.h2723. PMID: 26037642
Clinical practice guidelines for multiple endocrine neoplasia type 1 (MEN1).
Thakker RV, Newey PJ, Walls GV, Bilezikian J, Dralle H, Ebeling PR, Melmed S, Sakurai A, Tonelli F, Brandi ML; Endocrine Society
J Clin Endocrinol Metab 2012 Sep;97(9):2990-3011. Epub 2012 Jun 20 doi: 10.1210/jc.2012-1230. PMID: 22723327
Paraneoplastic syndromes: an approach to diagnosis and treatment.
Pelosof LC, Gerber DE
Mayo Clin Proc 2010 Sep;85(9):838-54. doi: 10.4065/mcp.2010.0099. PMID: 20810794Free PMC Article

Recent clinical studies

Etiology

Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules.
Nikiforova MN, Mercurio S, Wald AI, Barbi de Moura M, Callenberg K, Santana-Santos L, Gooding WE, Yip L, Ferris RL, Nikiforov YE
Cancer 2018 Apr 15;124(8):1682-1690. Epub 2018 Jan 18 doi: 10.1002/cncr.31245. PMID: 29345728Free PMC Article
Sonography of Normal and Abnormal Thyroid and Parathyroid Glands.
Andrioli M, Valcavi R
Front Horm Res 2016;45:1-15. Epub 2016 Mar 15 doi: 10.1159/000442273. PMID: 27002829
Clinicopathological correlates of hyperparathyroidism.
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Oct;68(10):771-87. Epub 2015 Jul 10 doi: 10.1136/jclinpath-2015-203186. PMID: 26163537
Primary hyperparathyroidism.
Akerström G, Hellman P
Curr Opin Oncol 2004 Jan;16(1):1-7. doi: 10.1097/00001622-200401000-00002. PMID: 14685084

Diagnosis

Parathyroid Imaging.
Lalonde MN, Correia RD, Syktiotis GP, Schaefer N, Matter M, Prior JO
Semin Nucl Med 2023 Jul;53(4):490-502. Epub 2023 Mar 14 doi: 10.1053/j.semnuclmed.2023.02.004. PMID: 36922339
Overview of the 2022 WHO Classification of Parathyroid Tumors.
Erickson LA, Mete O, Juhlin CC, Perren A, Gill AJ
Endocr Pathol 2022 Mar;33(1):64-89. Epub 2022 Feb 17 doi: 10.1007/s12022-022-09709-1. PMID: 35175514
Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Parathyroid Pathology.
Guilmette J, Sadow PM
Surg Pathol Clin 2019 Dec;12(4):1007-1019. Epub 2019 Sep 27 doi: 10.1016/j.path.2019.08.006. PMID: 31672291Free PMC Article
Parathyroid imaging.
Fakhran S, Branstetter BF 4th, Pryma DA
Neuroimaging Clin N Am 2008 Aug;18(3):537-49, ix. doi: 10.1016/j.nic.2008.03.006. PMID: 18656034

Therapy

Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Lithium-associated hyperparathyroidism.
Mifsud S, Cilia K, Mifsud EL, Gruppetta M
Br J Hosp Med (Lond) 2020 Nov 2;81(11):1-9. Epub 2020 Nov 17 doi: 10.12968/hmed.2020.0457. PMID: 33263481
Parathyroid cancer.
Lang B, Lo CY
Surg Oncol Clin N Am 2006 Jul;15(3):573-84. doi: 10.1016/j.soc.2006.05.003. PMID: 16882498
Primary hyperparathyroidism.
Akerström G, Hellman P
Curr Opin Oncol 2004 Jan;16(1):1-7. doi: 10.1097/00001622-200401000-00002. PMID: 14685084
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115

Prognosis

Advances and Updates in Parathyroid Pathology.
Gokozan HN, Scognamiglio T
Adv Anat Pathol 2023 Jan 1;30(1):24-33. Epub 2022 Nov 1 doi: 10.1097/PAP.0000000000000379. PMID: 36315270
Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Non-Neoplastic Mediastinal Cysts.
Syred K, Weissferdt A
Adv Anat Pathol 2020 Sep;27(5):294-302. doi: 10.1097/PAP.0000000000000261. PMID: 31972565
Analytical performance of the ThyroSeq v3 genomic classifier for cancer diagnosis in thyroid nodules.
Nikiforova MN, Mercurio S, Wald AI, Barbi de Moura M, Callenberg K, Santana-Santos L, Gooding WE, Yip L, Ferris RL, Nikiforov YE
Cancer 2018 Apr 15;124(8):1682-1690. Epub 2018 Jan 18 doi: 10.1002/cncr.31245. PMID: 29345728Free PMC Article
Primary hyperparathyroidism.
Akerström G, Hellman P
Curr Opin Oncol 2004 Jan;16(1):1-7. doi: 10.1097/00001622-200401000-00002. PMID: 14685084

Clinical prediction guides

Clinical predictors of ectopic parathyroid adenomas: experience with 421 confirmed parathyroid adenoma localizations.
Durmuş ET, Atmaca A, Kefeli M, Çolak R, Durmuş B, Polat C
J Endocrinol Invest 2023 Jun;46(6):1197-1203. Epub 2022 Dec 12 doi: 10.1007/s40618-022-01986-1. PMID: 36510103
Post-thyroidectomy hypoparathyroidism, what should we keep in mind?
Caglià P, Puglisi S, Buffone A, Bianco SL, Okatyeva V, Veroux M, Cannizzaro MA
Ann Ital Chir 2017;6:371-381. PMID: 29197191
Sonography of Normal and Abnormal Thyroid and Parathyroid Glands.
Andrioli M, Valcavi R
Front Horm Res 2016;45:1-15. Epub 2016 Mar 15 doi: 10.1159/000442273. PMID: 27002829
Magnesium: its role in nutrition and carcinogenesis.
Blaszczyk U, Duda-Chodak A
Rocz Panstw Zakl Hig 2013;64(3):165-71. PMID: 24325082
Sestamibi parathyroid imaging.
McBiles M, Lambert AT, Cote MG, Kim SY
Semin Nucl Med 1995 Jul;25(3):221-34. doi: 10.1016/s0001-2998(95)80012-3. PMID: 7570042

Recent systematic reviews

Treatment of hypercalcaemia of malignancy in adults.
Mc Donald D, Drake MT, Crowley RK
Clin Med (Lond) 2023 Sep;23(5):503-507. Epub 2023 Sep 29 doi: 10.7861/clinmed.2023-0227. PMID: 37775175Free PMC Article
Parathyroid carcinoma: Current management and outcomes - A systematic review.
McInerney NJ, Moran T, O'Duffy F
Am J Otolaryngol 2023 Jul-Aug;44(4):103843. Epub 2023 Mar 23 doi: 10.1016/j.amjoto.2023.103843. PMID: 36989753
Diagnosis and management of parathyroid carcinoma: a state-of-the-art review.
Roser P, Leca BM, Coelho C, Schulte KM, Gilbert J, Drakou EE, Kosmas C, Ling Chuah L, Wassati H, Miras AD, Crane J, Aylwin SJB, Grossman AB, Dimitriadis GK
Endocr Relat Cancer 2023 Apr 1;30(4) Epub 2023 Mar 22 doi: 10.1530/ERC-22-0287. PMID: 36621911
Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.
El-Hajj Fuleihan G, Clines GA, Hu MI, Marcocci C, Murad MH, Piggott T, Van Poznak C, Wu JY, Drake MT
J Clin Endocrinol Metab 2023 Feb 15;108(3):507-528. doi: 10.1210/clinem/dgac621. PMID: 36545746
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article

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