U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cyst of parathyroid

MedGen UID:
90980
•Concept ID:
C0342347
•
Anatomical Abnormality
Synonyms: Cyst of Parathyroid; Cyst of the Parathyroid; Parathyroid cyst; Parathyroid Cyst
SNOMED CT: Cyst of parathyroid (190459003); Parathyroid cyst (190459003)

Definition

An epithelium-lined, fluid-filled cyst containing parathyroid hormone that is usually located in an inferior parathyroid gland, but may be found in other locations in the neck or mediastinum. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVCyst of parathyroid

Professional guidelines

PubMed

2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
The diagnosis and management of hypercalcaemia.
Minisola S, Pepe J, Piemonte S, Cipriani C
BMJ 2015 Jun 2;350:h2723. doi: 10.1136/bmj.h2723. PMID: 26037642
Paraneoplastic syndromes: an approach to diagnosis and treatment.
Pelosof LC, Gerber DE
Mayo Clin Proc 2010 Sep;85(9):838-54. doi: 10.4065/mcp.2010.0099. PMID: 20810794Free PMC Article

Recent clinical studies

Etiology

Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Histopathological Features of Parathyroid Adenoma and 18F-Choline Uptake in PET/MR of Primary Hyperparathyroidism.
Liberini V, Morand GB, Rupp NJ, Orita E, Deandreis D, Broglie Däppen M, Hofbauer M, Maurer A, Husmann L, Mader CE, Grünig H, Alharbi AA, Messerli M, Huellner MW
Clin Nucl Med 2022 Feb 1;47(2):101-107. doi: 10.1097/RLU.0000000000003987. PMID: 35006103
Sonography of Normal and Abnormal Thyroid and Parathyroid Glands.
Andrioli M, Valcavi R
Front Horm Res 2016;45:1-15. Epub 2016 Mar 15 doi: 10.1159/000442273. PMID: 27002829
Clinicopathological correlates of hyperparathyroidism.
Duan K, Gomez Hernandez K, Mete O
J Clin Pathol 2015 Oct;68(10):771-87. Epub 2015 Jul 10 doi: 10.1136/jclinpath-2015-203186. PMID: 26163537
Primary hyperparathyroidism.
Akerström G, Hellman P
Curr Opin Oncol 2004 Jan;16(1):1-7. doi: 10.1097/00001622-200401000-00002. PMID: 14685084

Diagnosis

Update on Preoperative Parathyroid Localization in Primary Hyperparathyroidism.
Park HS, Hong N, Jeong JJ, Yun M, Rhee Y
Endocrinol Metab (Seoul) 2022 Oct;37(5):744-755. Epub 2022 Oct 25 doi: 10.3803/EnM.2022.1589. PMID: 36327985Free PMC Article
Overview of the 2022 WHO Classification of Parathyroid Tumors.
Erickson LA, Mete O, Juhlin CC, Perren A, Gill AJ
Endocr Pathol 2022 Mar;33(1):64-89. Epub 2022 Feb 17 doi: 10.1007/s12022-022-09709-1. PMID: 35175514
Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Preoperative and Intraoperative Methods of Parathyroid Gland Localization and the Diagnosis of Parathyroid Adenomas.
Baj J, Sitarz R, Łokaj M, Forma A, Czeczelewski M, Maani A, Garruti G
Molecules 2020 Apr 9;25(7) doi: 10.3390/molecules25071724. PMID: 32283730Free PMC Article
Parathyroid Pathology.
Guilmette J, Sadow PM
Surg Pathol Clin 2019 Dec;12(4):1007-1019. Epub 2019 Sep 27 doi: 10.1016/j.path.2019.08.006. PMID: 31672291Free PMC Article

Therapy

Surgery for primary hyperparathyroidism.
das Neves MC, Santos RO, Ohe MN
Arch Endocrinol Metab 2022 Nov 11;66(5):678-688. doi: 10.20945/2359-3997000000557. PMID: 36382757Free PMC Article
Lithium-associated hyperparathyroidism.
Mifsud S, Cilia K, Mifsud EL, Gruppetta M
Br J Hosp Med (Lond) 2020 Nov 2;81(11):1-9. Epub 2020 Nov 17 doi: 10.12968/hmed.2020.0457. PMID: 33263481
Post-thyroidectomy hypoparathyroidism, what should we keep in mind?
Caglià P, Puglisi S, Buffone A, Bianco SL, Okatyeva V, Veroux M, Cannizzaro MA
Ann Ital Chir 2017;6:371-381. PMID: 29197191
Medullary thyroid cancer: management guidelines of the American Thyroid Association.
American Thyroid Association Guidelines Task Force, Kloos RT, Eng C, Evans DB, Francis GL, Gagel RF, Gharib H, Moley JF, Pacini F, Ringel MD, Schlumberger M, Wells SA Jr
Thyroid 2009 Jun;19(6):565-612. doi: 10.1089/thy.2008.0403. PMID: 19469690
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115

Prognosis

Parathyroid Imaging.
Itani M, Middleton WD
Radiol Clin North Am 2020 Nov;58(6):1071-1083. Epub 2020 Sep 17 doi: 10.1016/j.rcl.2020.07.006. PMID: 33040849
Non-Neoplastic Mediastinal Cysts.
Syred K, Weissferdt A
Adv Anat Pathol 2020 Sep;27(5):294-302. doi: 10.1097/PAP.0000000000000261. PMID: 31972565
Post-thyroidectomy hypoparathyroidism, what should we keep in mind?
Caglià P, Puglisi S, Buffone A, Bianco SL, Okatyeva V, Veroux M, Cannizzaro MA
Ann Ital Chir 2017;6:371-381. PMID: 29197191
Primary hyperparathyroidism.
Akerström G, Hellman P
Curr Opin Oncol 2004 Jan;16(1):1-7. doi: 10.1097/00001622-200401000-00002. PMID: 14685084
Parathyroid carcinoma.
Kebebew E
Curr Treat Options Oncol 2001 Aug;2(4):347-54. doi: 10.1007/s11864-001-0028-2. PMID: 12057115

Clinical prediction guides

Post-thyroidectomy hypoparathyroidism, what should we keep in mind?
Caglià P, Puglisi S, Buffone A, Bianco SL, Okatyeva V, Veroux M, Cannizzaro MA
Ann Ital Chir 2017;6:371-381. PMID: 29197191
Sonography of Normal and Abnormal Thyroid and Parathyroid Glands.
Andrioli M, Valcavi R
Front Horm Res 2016;45:1-15. Epub 2016 Mar 15 doi: 10.1159/000442273. PMID: 27002829
Magnesium: its role in nutrition and carcinogenesis.
Blaszczyk U, Duda-Chodak A
Rocz Panstw Zakl Hig 2013;64(3):165-71. PMID: 24325082
Sestamibi parathyroid imaging.
McBiles M, Lambert AT, Cote MG, Kim SY
Semin Nucl Med 1995 Jul;25(3):221-34. doi: 10.1016/s0001-2998(95)80012-3. PMID: 7570042
Parathyroid cytopathology.
Davey DD, Glant MD, Berger EK
Diagn Cytopathol 1986 Jan-Mar;2(1):76-80. doi: 10.1002/dc.2840020116. PMID: 2424691

Recent systematic reviews

Diagnosis and management of parathyroid carcinoma: a state-of-the-art review.
Roser P, Leca BM, Coelho C, Schulte KM, Gilbert J, Drakou EE, Kosmas C, Ling Chuah L, Wassati H, Miras AD, Crane J, Aylwin SJB, Grossman AB, Dimitriadis GK
Endocr Relat Cancer 2023 Apr 1;30(4) Epub 2023 Mar 22 doi: 10.1530/ERC-22-0287. PMID: 36621911
Treatment of Hypercalcemia of Malignancy in Adults: An Endocrine Society Clinical Practice Guideline.
El-Hajj Fuleihan G, Clines GA, Hu MI, Marcocci C, Murad MH, Piggott T, Van Poznak C, Wu JY, Drake MT
J Clin Endocrinol Metab 2023 Feb 15;108(3):507-528. doi: 10.1210/clinem/dgac621. PMID: 36545746
2021 American Thyroid Association Guidelines for Management of Patients with Anaplastic Thyroid Cancer.
Bible KC, Kebebew E, Brierley J, Brito JP, Cabanillas ME, Clark TJ Jr, Di Cristofano A, Foote R, Giordano T, Kasperbauer J, Newbold K, Nikiforov YE, Randolph G, Rosenthal MS, Sawka AM, Shah M, Shaha A, Smallridge R, Wong-Clark CK
Thyroid 2021 Mar;31(3):337-386. doi: 10.1089/thy.2020.0944. PMID: 33728999Free PMC Article
Parathyroid cancer: A systematic review of diagnostic biomarkers.
Davies MP, John Evans TW, Tahir F, Balasubramanian SP
Surgeon 2021 Dec;19(6):e536-e548. Epub 2021 Feb 26 doi: 10.1016/j.surge.2021.01.011. PMID: 33642204
Vitamin D Receptor Polymorphisms and Cancer.
Gnagnarella P, Raimondi S, Aristarco V, Johansson HA, Bellerba F, Corso F, Gandini S
Adv Exp Med Biol 2020;1268:53-114. doi: 10.1007/978-3-030-46227-7_4. PMID: 32918214

Supplemental Content

Table of contents

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.
    • Bookshelf
      See practice and clinical guidelines in NCBI Bookshelf. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...