U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tracheal adenoid cystic carcinoma

MedGen UID:
91058
•Concept ID:
C0345945
•
Neoplastic Process
Synonyms: Adenoid Cystic Carcinoma of the Trachea; adenoid cystic carcinoma of the trachea; Adenoid cystic carcinoma of trachea; Adenoid Cystic Carcinoma of Trachea; adenoid cystic carcinoma of trachea; Cylindroma of trachea; Trachea Adenoid Cystic Carcinoma; trachea adenoid cystic carcinoma; Tracheal Adenoid Cystic Carcinoma; tracheal adenoid cystic carcinoma
SNOMED CT: Adenoid cystic carcinoma of trachea (254619006); Cylindroma of trachea (254619006)
 
Monarch Initiative: MONDO:0006471

Definition

An adenoid cystic carcinoma that arises from the trachea. It spreads to the submucosal tracheal tissue and to regional lymph nodes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTracheal adenoid cystic carcinoma

Professional guidelines

PubMed

Patterns of Care and Outcomes of Primary Adenoid Cystic Carcinoma of the Trachea.
Behbahani S, Barinsky GL, Wassef D, Paskhover B, Kaye R
Ann Otol Rhinol Laryngol 2022 Jan;131(1):78-85. Epub 2021 Apr 19 doi: 10.1177/00034894211008101. PMID: 33870720
Clinical features, treatment and outcomes in patients with tracheal adenoid cystic carcinoma: a systematic literature review.
Ran J, Qu G, Chen X, Zhao D
Radiat Oncol 2021 Feb 19;16(1):38. doi: 10.1186/s13014-021-01770-0. PMID: 33608038Free PMC Article
Primary tracheal adenoid cystic carcinoma: adjuvant treatment outcome.
Chen F, Huang M, Xu Y, Li T, Xie K, Zhang L, Cheng D, Liu L, Che G, Hou M, Wang J, Luo Z, Lu Y
Int J Clin Oncol 2015 Aug;20(4):686-92. Epub 2014 Nov 21 doi: 10.1007/s10147-014-0771-6. PMID: 25412605

Recent clinical studies

Etiology

Patterns of Care and Outcomes of Primary Adenoid Cystic Carcinoma of the Trachea.
Behbahani S, Barinsky GL, Wassef D, Paskhover B, Kaye R
Ann Otol Rhinol Laryngol 2022 Jan;131(1):78-85. Epub 2021 Apr 19 doi: 10.1177/00034894211008101. PMID: 33870720
CT diagnosis and prognosis prediction of tracheal adenoid cystic carcinoma.
Wang SC, Yin LK, Zhang Y, Xue LM, Ye JD, Tao GY, Yu H, Qiang JW
Eur J Radiol 2021 Jul;140:109746. Epub 2021 Apr 30 doi: 10.1016/j.ejrad.2021.109746. PMID: 33992979
Impact of Positive Margins and Radiation After Tracheal Adenoid Cystic Carcinoma Resection on Survival.
Yang CJ, Shah SA, Ramakrishnan D, Raman V, Diao K, Wang H, Commander SJ, D'Amico TA, Berry MF
Ann Thorac Surg 2020 Apr;109(4):1026-1032. Epub 2019 Oct 4 doi: 10.1016/j.athoracsur.2019.08.094. PMID: 31589850
Resected Tracheal Adenoid Cystic Carcinoma: Improvements in Outcome at a Single Institution.
Yang H, Yao F, Tantai J, Zhao Y, Tan Q, Zhao H
Ann Thorac Surg 2016 Jan;101(1):294-300. Epub 2015 Oct 1 doi: 10.1016/j.athoracsur.2015.06.073. PMID: 26431923
Primary tracheal adenoid cystic carcinoma: adjuvant treatment outcome.
Chen F, Huang M, Xu Y, Li T, Xie K, Zhang L, Cheng D, Liu L, Che G, Hou M, Wang J, Luo Z, Lu Y
Int J Clin Oncol 2015 Aug;20(4):686-92. Epub 2014 Nov 21 doi: 10.1007/s10147-014-0771-6. PMID: 25412605

Diagnosis

Patterns of Care and Outcomes of Primary Adenoid Cystic Carcinoma of the Trachea.
Behbahani S, Barinsky GL, Wassef D, Paskhover B, Kaye R
Ann Otol Rhinol Laryngol 2022 Jan;131(1):78-85. Epub 2021 Apr 19 doi: 10.1177/00034894211008101. PMID: 33870720
CT diagnosis and prognosis prediction of tracheal adenoid cystic carcinoma.
Wang SC, Yin LK, Zhang Y, Xue LM, Ye JD, Tao GY, Yu H, Qiang JW
Eur J Radiol 2021 Jul;140:109746. Epub 2021 Apr 30 doi: 10.1016/j.ejrad.2021.109746. PMID: 33992979
Metastases from tracheal adenoid cystic carcinoma.
Tan VSR, Li A, Seet JE, Lee P
Thorax 2021 Feb;76(2):208-209. Epub 2020 Oct 6 doi: 10.1136/thoraxjnl-2020-215760. PMID: 33023994
Resected Tracheal Adenoid Cystic Carcinoma: Improvements in Outcome at a Single Institution.
Yang H, Yao F, Tantai J, Zhao Y, Tan Q, Zhao H
Ann Thorac Surg 2016 Jan;101(1):294-300. Epub 2015 Oct 1 doi: 10.1016/j.athoracsur.2015.06.073. PMID: 26431923
Tracheal adenoid cystic carcinoma.
Lakhkar BN, Patil UD, Ghosh MK, Shenoy PD
Indian J Chest Dis Allied Sci 1992 Jul-Sep;34(3):141-4. PMID: 1338781

Therapy

Therapeutic bronchoscopy followed by sequential radiochemotherapy in the management of life-threatening tracheal adenoid cystic carcinoma: a case report.
Elhidsi M, Zaini J, Ghanie A, Huswatun AL, Beginta R, Mety SH, Syahruddin E
J Med Case Rep 2022 Jun 20;16(1):243. doi: 10.1186/s13256-022-03452-1. PMID: 35718781Free PMC Article
Response of NOTCH1-Activated Tracheal Adenoid Cystic Carcinoma to the Gamma Secretase Inhibitor Nirogacestat.
Kieran R, de Paula BHR, Hubank M, Barker A, Paterson AL, Gilligan D, Doherty GJ
JCO Precis Oncol 2021 Nov;5:1579-1583. doi: 10.1200/PO.21.00228. PMID: 34994644
Case report of apatinib mesylate treatment in rare advanced tracheal adenoid cystic carcinoma.
Wang H
Thorac Cancer 2017 Nov;8(6):729-733. Epub 2017 Sep 11 doi: 10.1111/1759-7714.12506. PMID: 28892250Free PMC Article
Percutaneous CT-fluoroscopic-guided radioisotope seed placement for the management of adenoid cystic carcinoma of the trachea.
Doggett S, Chino S, Lempert T, Federhart J
Brachytherapy 2017 May-Jun;16(3):639-645. Epub 2016 Dec 28 doi: 10.1016/j.brachy.2016.11.007. PMID: 28039009
Definitive radiotherapy for unresected adenoid cystic carcinoma of the trachea.
Bonner Millar LP, Stripp D, Cooper JD, Both S, James P, Rengan R
Chest 2012 May;141(5):1323-1326. doi: 10.1378/chest.11-0925. PMID: 22553266

Prognosis

A population study comparing tracheal and lung adenoid cystic carcinoma.
Gu Y, Lai S, Wang Y, Yang J, Zhou P, Chen T
Cancer Med 2024 Apr;13(7):e7158. doi: 10.1002/cam4.7158. PMID: 38572933Free PMC Article
Patterns of Care and Outcomes of Primary Adenoid Cystic Carcinoma of the Trachea.
Behbahani S, Barinsky GL, Wassef D, Paskhover B, Kaye R
Ann Otol Rhinol Laryngol 2022 Jan;131(1):78-85. Epub 2021 Apr 19 doi: 10.1177/00034894211008101. PMID: 33870720
CT diagnosis and prognosis prediction of tracheal adenoid cystic carcinoma.
Wang SC, Yin LK, Zhang Y, Xue LM, Ye JD, Tao GY, Yu H, Qiang JW
Eur J Radiol 2021 Jul;140:109746. Epub 2021 Apr 30 doi: 10.1016/j.ejrad.2021.109746. PMID: 33992979
Impact of Positive Margins and Radiation After Tracheal Adenoid Cystic Carcinoma Resection on Survival.
Yang CJ, Shah SA, Ramakrishnan D, Raman V, Diao K, Wang H, Commander SJ, D'Amico TA, Berry MF
Ann Thorac Surg 2020 Apr;109(4):1026-1032. Epub 2019 Oct 4 doi: 10.1016/j.athoracsur.2019.08.094. PMID: 31589850
Resected Tracheal Adenoid Cystic Carcinoma: Improvements in Outcome at a Single Institution.
Yang H, Yao F, Tantai J, Zhao Y, Tan Q, Zhao H
Ann Thorac Surg 2016 Jan;101(1):294-300. Epub 2015 Oct 1 doi: 10.1016/j.athoracsur.2015.06.073. PMID: 26431923

Clinical prediction guides

A population study comparing tracheal and lung adenoid cystic carcinoma.
Gu Y, Lai S, Wang Y, Yang J, Zhou P, Chen T
Cancer Med 2024 Apr;13(7):e7158. doi: 10.1002/cam4.7158. PMID: 38572933Free PMC Article
CT diagnosis and prognosis prediction of tracheal adenoid cystic carcinoma.
Wang SC, Yin LK, Zhang Y, Xue LM, Ye JD, Tao GY, Yu H, Qiang JW
Eur J Radiol 2021 Jul;140:109746. Epub 2021 Apr 30 doi: 10.1016/j.ejrad.2021.109746. PMID: 33992979
Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix.
Li P, Li S, Tang Q, He X, Yin D, Wang S, Yang X
Auris Nasus Larynx 2017 Apr;44(2):237-240. Epub 2016 Apr 24 doi: 10.1016/j.anl.2016.04.008. PMID: 27117221
Primary tracheal adenoid cystic carcinoma: adjuvant treatment outcome.
Chen F, Huang M, Xu Y, Li T, Xie K, Zhang L, Cheng D, Liu L, Che G, Hou M, Wang J, Luo Z, Lu Y
Int J Clin Oncol 2015 Aug;20(4):686-92. Epub 2014 Nov 21 doi: 10.1007/s10147-014-0771-6. PMID: 25412605
Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma.
Honings J, Gaissert HA, Weinberg AC, Mark EJ, Wright CD, Wain JC, Mathisen DJ
Eur J Cardiothorac Surg 2010 Jun;37(6):1438-44. Epub 2010 Mar 30 doi: 10.1016/j.ejcts.2010.01.005. PMID: 20356756

Recent systematic reviews

Clinical features, treatment and outcomes in patients with tracheal adenoid cystic carcinoma: a systematic literature review.
Ran J, Qu G, Chen X, Zhao D
Radiat Oncol 2021 Feb 19;16(1):38. doi: 10.1186/s13014-021-01770-0. PMID: 33608038Free PMC Article

Supplemental Content

Table of contents

    Clinical resources

    Practice guidelines

    • PubMed
      See practice and clinical guidelines in PubMed. The search results may include broader topics and may not capture all published guidelines. See the FAQ for details.

    Consumer resources

    Reviews

    Related information

    • PMC Articles
      Related information in PubMed Central Links
    • PubMed
      Related literature resources in PubMed

    Recent activity

    Clear Turn Off Turn On

    Your browsing activity is empty.

    Activity recording is turned off.

    Turn recording back on

    See more...