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Verruciform xanthoma

MedGen UID:: 91076
•Concept ID:: C0346054
•: Neoplastic Process

Synonyms:	Cutaneous Verruciform Xanthoma; cutaneous verruciform xanthoma; Histiocytosis Y; Skin Verruciform Xanthoma; skin verruciform xanthoma; Verruciform Xanthoma; verruciform xanthoma; verruciform xanthoma (morphologic abnormality); Verruciform xanthoma of skin; Verruciform Xanthoma of Skin; verruciform xanthoma of skin; Verruciform Xanthoma of the Skin; verruciform xanthoma of the skin
SNOMED CT:	Verruciform xanthoma (66174008); Histiocytosis Y (66174008); Verruciform xanthoma of skin (254756007)

HPO:	HP:0031517
Monarch Initiative:	MONDO:0003640

Definition

A papillary or cauliflower-like growth characterized by the presence of foamy histiocytes within the elongated dermal papillae forms. [from HPO]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVVerruciform xanthoma

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Non-Neoplastic Disorder
      - Non-Neoplastic Disorder by Site
        Non-Neoplastic Skin Disorder
        Verruciform xanthoma

Recent clinical studies

Etiology

Oral verruciform xanthoma in chronic graft-versus-host disease patients.

Bar O, Elad S, Avni B, Abu-Tair J, Zaharia B, Hanut A, Zadik Y
Support Care Cancer 2021 Jan;29(1):79-84. Epub 2020 Aug 15 doi: 10.1007/s00520-020-05681-w. PMID: 32803727

Betz SJ
Head Neck Pathol 2019 Mar;13(1):80-90. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01003-7. PMID: 30693456 Free PMC Article

Oral verruciform xanthoma: Report of 13 new cases and review of the literature.

Tamiolakis P, Theofilou VI, Tosios KI, Sklavounou-Andrikopoulou A
Med Oral Patol Oral Cir Bucal 2018 Jul 1;23(4):e429-e435. doi: 10.4317/medoral.22342. PMID: 29924759 Free PMC Article

A case of multiple verruciform xanthoma in gingiva.

Qi Y, Sun Q, Yang P, Song A
Br J Oral Maxillofac Surg 2014 Jan;52(1):e1-3. Epub 2013 Oct 19 doi: 10.1016/j.bjoms.2013.09.016. PMID: 24148701

Verruciform xanthoma occurring within oral lichen planus.

Miyamoto Y, Nagayama M, Hayashi Y
J Oral Pathol Med 1996 Apr;25(4):188-91. doi: 10.1111/j.1600-0714.1996.tb00218.x. PMID: 8809688

See all (21)

Diagnosis

Subungual Verruciform Xanthoma.

Haneke E
Dermatol Surg 2021 May 1;47(5):722-724. doi: 10.1097/DSS.0000000000002640. PMID: 33481453

Betz SJ
Head Neck Pathol 2019 Mar;13(1):80-90. Epub 2019 Jan 29 doi: 10.1007/s12105-019-01003-7. PMID: 30693456 Free PMC Article

Oral verruciform xanthoma.

Harris L, Staines K, Pring M
BMJ Case Rep 2015 Mar 27;2015 doi: 10.1136/bcr-2014-209216. PMID: 25819830 Free PMC Article

Verruciform xanthoma.

Gill BJ, Chan AJ, Hsu S
Dermatol Online J 2014 Jan 15;20(1):21253. PMID: 24456956

Verruciform xanthoma.

Robinson MR, Meehan SA
Cutis 2013 Jun;91(6):272, 285-6. PMID: 23837157

See all (82)

Therapy

Verruciform Genital-Associated (Vegas) Xanthoma: report of a patient with verruciform xanthoma of the scrotum and literature review.

Beutler BD, Cohen PR
Dermatol Online J 2015 Aug 15;21(8) PMID: 26437158

Disseminated verruciform xanthoma: a case report.

Tang R, Kopp SA, Cobb C, Halpern AV
Cutis 2014 Jun;93(6):307-10. PMID: 24999643

Verruciform xanthoma: report of two cases.

Teixeira V, Reis JP, Tellechea Ó, Vieira R, Figueiredo A
Dermatol Online J 2012 May 15;18(5):10. PMID: 22630580

Verruciform xanthoma in a bone marrow transplant recipient.

Allen CM, Kapoor N
Oral Surg Oral Med Oral Pathol 1993 May;75(5):591-4. doi: 10.1016/0030-4220(93)90231-r. PMID: 8488027

Verruciform xanthoma of the ear with coexisting epidermal dysplasia.

Jensen JL, Liao SY, Jeffes EW 3rd
Am J Dermatopathol 1992 Oct;14(5):426-30. doi: 10.1097/00000372-199210000-00009. PMID: 1329573

See all (8)

Prognosis

Oral verruciform xanthoma and erythroplakia associated with chronic graft-versus-host disease: a rare case report and review of the literature.

Capocasale G, Panzarella V, Tozzo P, Mauceri R, Rodolico V, Lauritano D, Campisi G
BMC Res Notes 2017 Nov 28;10(1):631. doi: 10.1186/s13104-017-2952-7. PMID: 29183344 Free PMC Article

CHILD syndrome with mild skin lesions: histopathologic clues for the diagnosis.

Gantner S, Rütten A, Requena L, Gassenmaier G, Landthaler M, Hafner C
J Cutan Pathol 2014 Oct;41(10):787-90. Epub 2014 Oct 18 doi: 10.1111/cup.12377. PMID: 25093865

A case of multiple verruciform xanthoma in gingiva.

Qi Y, Sun Q, Yang P, Song A
Br J Oral Maxillofac Surg 2014 Jan;52(1):e1-3. Epub 2013 Oct 19 doi: 10.1016/j.bjoms.2013.09.016. PMID: 24148701

Verruciform xanthoma--biological profile of 282 oral lesions based on a literature survey with nine new cases from Japan.

Philipsen HP, Reichart PA, Takata T, Ogawa I
Oral Oncol 2003 Jun;39(4):325-36. doi: 10.1016/s1368-8375(02)00088-x. PMID: 12676251

Verruciform xanthoma occurring within oral lichen planus.

Miyamoto Y, Nagayama M, Hayashi Y
J Oral Pathol Med 1996 Apr;25(4):188-91. doi: 10.1111/j.1600-0714.1996.tb00218.x. PMID: 8809688

See all (10)

Clinical prediction guides

Oral verruciform xanthoma and erythroplakia associated with chronic graft-versus-host disease: a rare case report and review of the literature.

Capocasale G, Panzarella V, Tozzo P, Mauceri R, Rodolico V, Lauritano D, Campisi G
BMC Res Notes 2017 Nov 28;10(1):631. doi: 10.1186/s13104-017-2952-7. PMID: 29183344 Free PMC Article

Verruciform Genital-Associated (Vegas) Xanthoma: report of a patient with verruciform xanthoma of the scrotum and literature review.

Beutler BD, Cohen PR
Dermatol Online J 2015 Aug 15;21(8) PMID: 26437158

Vulvar verruciform xanthoma: ten cases associated with lichen sclerosus, lichen planus, or other conditions.

Fite C, Plantier F, Dupin N, Avril MF, Moyal-Barracco M
Arch Dermatol 2011 Sep;147(9):1087-92. Epub 2011 May 16 doi: 10.1001/archdermatol.2011.113. PMID: 21576553

Verruciform xanthoma of the esophagus.

Herrera-Goepfert R, Lizano-Soberón M, García-Perales M
Hum Pathol 2003 Aug;34(8):814-5. doi: 10.1016/s0046-8177(03)00236-3. PMID: 14506645

Ultrastructural features of the verruciform xanthoma.

Cobb CM, Holt R, Denys FR
J Oral Pathol 1976 Jan;5(1):42-51. doi: 10.1111/j.1600-0714.1976.tb01756.x. PMID: 814219

See all (11)