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Pineal parenchymal cell neoplasm

MedGen UID:
910833
Concept ID:
CN241427
Finding
Synonyms: neoplasm of pineal gland; neoplasm of the pineal gland; pineal gland neoplasm; pineal gland tumor; pineal gland tumour; pineal parenchymal cell neoplasm; pineal parenchymal cell tumor; pineal parenchymal cell tumour; pineal parenchymal neoplasm; pineal parenchymal tumor; pineal parenchymal tumour; pineocytic neoplasm; pineocytic tumor; pineocytic tumour; tumor of pineal gland; tumor of the pineal gland; tumour of pineal gland; tumour of the pineal gland
 
HPO: HP:0030694
Monarch Initiative: MONDO:0024890

Definition

A neoplasm arising from the pineocyte, a cell with photosensory and neuroendocrine functions. It may be composed of mature elements or primitive, immature cells. The cellular composition determines the biological behavior and clinical outcome. Three types are recognized: pineoblastoma, pineocytoma, and pineal parenchymal tumor of intermediate differentiation (Adapted from WHO.) [from MONDO]

Professional guidelines

PubMed

Mynarek M, Pizer B, Dufour C, van Vuurden D, Garami M, Massimino M, Fangusaro J, Davidson T, Gil-da-Costa MJ, Sterba J, Benesch M, Gerber N, Juhnke BO, Kwiecien R, Pietsch T, Kool M, Clifford S, Ellison DW, Giangaspero F, Wesseling P, Gilles F, Gottardo N, Finlay JL, Rutkowski S, von Hoff K
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Recent clinical studies

Etiology

Zaccagna F, Brown FS, Allinson KSJ, Devadass A, Kapadia A, Massoud TF, Matys T
Clin Radiol 2022 Feb;77(2):e107-e119. Epub 2021 Nov 11 doi: 10.1016/j.crad.2021.09.020. PMID: 34774298
Liu APY, Li BK, Pfaff E, Gudenas B, Vasiljevic A, Orr BA, Dufour C, Snuderl M, Karajannis MA, Rosenblum MK, Hwang EI, Ng HK, Hansford JR, Szathmari A, Faure-Conter C, Merchant TE, Levine M, Bouvier N, von Hoff K, Mynarek M, Rutkowski S, Sahm F, Kool M, Hawkins C, Onar-Thomas A, Robinson GW, Gajjar A, Pfister SM, Bouffet E, Northcott PA, Jones DTW, Huang A
Acta Neuropathol 2021 May;141(5):771-785. Epub 2021 Feb 22 doi: 10.1007/s00401-021-02284-5. PMID: 33619588Free PMC Article
Kamihara J, Bourdeaut F, Foulkes WD, Molenaar JJ, Mossé YP, Nakagawara A, Parareda A, Scollon SR, Schneider KW, Skalet AH, States LJ, Walsh MF, Diller LR, Brodeur GM
Clin Cancer Res 2017 Jul 1;23(13):e98-e106. doi: 10.1158/1078-0432.CCR-17-0652. PMID: 28674118Free PMC Article
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075
Linggood RM, Chapman PH
J Neurooncol 1992 Jan;12(1):85-91. doi: 10.1007/BF00172460. PMID: 1541982

Diagnosis

Upadhyayula PS, Neira JA, Miller ML, Bruce JN
Adv Exp Med Biol 2023;1405:153-173. doi: 10.1007/978-3-031-23705-8_6. PMID: 37452938
Deiana G, Mottolese C, Hermier M, Louis-Tisserand G, Berthezene Y
Neurochirurgie 2015 Apr-Jun;61(2-3):113-22. Epub 2015 Feb 9 doi: 10.1016/j.neuchi.2014.10.111. PMID: 25676911
Vasiljevic A, Szathmari A, Champier J, Fèvre-Montange M, Jouvet A
Neurochirurgie 2015 Apr-Jun;61(2-3):130-7. Epub 2014 Apr 13 doi: 10.1016/j.neuchi.2013.06.006. PMID: 24726316
Linggood RM, Chapman PH
J Neurooncol 1992 Jan;12(1):85-91. doi: 10.1007/BF00172460. PMID: 1541982
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580

Therapy

Liu APY, Li BK, Pfaff E, Gudenas B, Vasiljevic A, Orr BA, Dufour C, Snuderl M, Karajannis MA, Rosenblum MK, Hwang EI, Ng HK, Hansford JR, Szathmari A, Faure-Conter C, Merchant TE, Levine M, Bouvier N, von Hoff K, Mynarek M, Rutkowski S, Sahm F, Kool M, Hawkins C, Onar-Thomas A, Robinson GW, Gajjar A, Pfister SM, Bouffet E, Northcott PA, Jones DTW, Huang A
Acta Neuropathol 2021 May;141(5):771-785. Epub 2021 Feb 22 doi: 10.1007/s00401-021-02284-5. PMID: 33619588Free PMC Article
Sonabend AM, Bowden S, Bruce JN
J Neurooncol 2016 Nov;130(2):351-366. Epub 2016 May 19 doi: 10.1007/s11060-016-2138-5. PMID: 27193692
Antoneli CB, Ribeiro Kde C, Sakamoto LH, Chojniak MM, Novaes PE, Arias VE
Pediatr Blood Cancer 2007 Mar;48(3):306-10. doi: 10.1002/pbc.20793. PMID: 16572402
Blakeley JO, Grossman SA
Curr Treat Options Oncol 2006 Nov;7(6):505-16. doi: 10.1007/s11864-006-0025-6. PMID: 17032562
Cuccia V, Rodríguez F, Palma F, Zuccaro G
Childs Nerv Syst 2006 Jun;22(6):577-85. Epub 2006 Mar 23 doi: 10.1007/s00381-006-0095-6. PMID: 16555075

Prognosis

Sonabend AM, Bowden S, Bruce JN
J Neurooncol 2016 Nov;130(2):351-366. Epub 2016 May 19 doi: 10.1007/s11060-016-2138-5. PMID: 27193692
Mottolese C, Szathmari A, Beuriat PA
Neurochirurgie 2015 Apr-Jun;61(2-3):65-9. Epub 2014 Aug 10 doi: 10.1016/j.neuchi.2014.01.005. PMID: 25113513
Srinivasan N, Pakala A, Mukkamalla C, Oswal A
South Med J 2010 Oct;103(10):1031-7. doi: 10.1097/SMJ.0b013e3181ebeeff. PMID: 20818311
Linggood RM, Chapman PH
J Neurooncol 1992 Jan;12(1):85-91. doi: 10.1007/BF00172460. PMID: 1541982
Baumgartner JE, Edwards MS
Neurosurg Clin N Am 1992 Oct;3(4):853-62. PMID: 1392580

Clinical prediction guides

Phuttharak W, Wannasarnmetha M, Lueangingkasut P, Waraasawapati S, Mukherji SK
Eur J Radiol 2023 Feb;159:110663. Epub 2022 Dec 20 doi: 10.1016/j.ejrad.2022.110663. PMID: 36584565
Ogiwara H
Childs Nerv Syst 2023 Sep;39(9):2349-2352. Epub 2022 Oct 1 doi: 10.1007/s00381-022-05676-4. PMID: 36181520
Zhu Y, Li Z, Xiong Z, Zhang T, Chen J
Contrast Media Mol Imaging 2022;2022:5702309. Epub 2022 Aug 10 doi: 10.1155/2022/5702309. PMID: 36017015Free PMC Article
Chalif EJ, Murray RD, Mozaffari K, Chillakuru YR, Shim T, Monfared A, Sherman JH
Neurosurgery 2022 Jun 1;90(6):807-815. Epub 2022 Mar 23 doi: 10.1227/neu.0000000000001915. PMID: 35311743
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Recent systematic reviews

Palmisciano P, Ogasawara C, Nwagwu CD, Bin Alamer O, Gupta AD, Giantini-Larsen AM, Scalia G, Yu K, Umana GE, Cohen-Gadol AA, El Ahmadieh TY, Haider AS
World Neurosurg 2022 Mar;159:156-167.e2. Epub 2022 Jan 6 doi: 10.1016/j.wneu.2022.01.005. PMID: 34999267Free PMC Article
Takase H, Tanoshima R, Singla N, Nakamura Y, Yamamoto T
Neurosurg Rev 2022 Apr;45(2):1135-1155. Epub 2021 Oct 20 doi: 10.1007/s10143-021-01674-3. PMID: 34668090
Yamaki VN, Solla DJF, Ribeiro RR, da Silva SA, Teixeira MJ, Figueiredo EG
Neurosurgery 2019 Sep 1;85(3):E420-E429. doi: 10.1093/neuros/nyz062. PMID: 30989225
Clark AJ, Ivan ME, Sughrue ME, Yang I, Aranda D, Han SJ, Kane AJ, Parsa AT
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Ophthalmology 2003 Oct;110(10):1983-8. doi: 10.1016/S0161-6420(03)00484-6. PMID: 14522775

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