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Oncocytoma of kidney

MedGen UID:
Concept ID:
Neoplastic Process
Synonyms: Oncocytoma kidney; Renal oncocytoma
SNOMED CT: Oncocytoma of kidney (254922006)
HPO: HP:0011798
Monarch Initiative: MONDO:0003825


A renal tumor originating from an oncocyte, which is an epithelial cell characterized by an excessive amount of mitochondria, resulting in an abundant acidophilic, granular cytoplasm. [from HPO]

Conditions with this feature

Oxyphilic adenoma
MedGen UID:
Concept ID:
Neoplastic Process
Oncocytomas are usually benign tumors that occur in various organs but particularly in the kidneys. Histologic evaluation of renal oncocytomas shows that they are composed entirely of peculiar epithelial cells with granular eosinophilic cytoplasm. Ultrastructural characterization exhibits densely packed cells with mitochondria, which show morphologic differences from those in normal cells. On the average they are larger than those in renal carcinoma cells and their shape is abnormal (summary by Welter et al., 1989).

Professional guidelines


Trpkov K, Hes O, Williamson SR, Adeniran AJ, Agaimy A, Alaghehbandan R, Amin MB, Argani P, Chen YB, Cheng L, Epstein JI, Cheville JC, Comperat E, da Cunha IW, Gordetsky JB, Gupta S, He H, Hirsch MS, Humphrey PA, Kapur P, Kojima F, Lopez JI, Maclean F, Magi-Galluzzi C, McKenney JK, Mehra R, Menon S, Netto GJ, Przybycin CG, Rao P, Rao Q, Reuter VE, Saleeb RM, Shah RB, Smith SC, Tickoo S, Tretiakova MS, True L, Verkarre V, Wobker SE, Zhou M, Gill AJ
Mod Pathol 2021 Jul;34(7):1392-1424. Epub 2021 Mar 4 doi: 10.1038/s41379-021-00779-w. PMID: 33664427
Baranovska VV *, Romanenko АМ, Zakhartseva LM
Exp Oncol 2020 Sep;42(3):233-237. doi: 10.32471/exp-oncology.2312-8852.vol-42-no-3.14968. PMID: 32996740
Abdessater M, Kanbar A, Comperat E, Dupont-Athenor A, Alechinsky L, Mouton M, Sebe P
Urology 2020 Sep;143:173-180. Epub 2020 Jun 5 doi: 10.1016/j.urology.2020.05.047. PMID: 32512107

Recent clinical studies


Johnson JR, Thurman AE, Metter JB, Bannayan GA
Urology 1979 Aug;14(2):181-5. doi: 10.1016/0090-4295(79)90157-2. PMID: 473471

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