Testicular sertoli cell tumor

MedGen UID:: 91165
•Concept ID:: C0349671
•: Neoplastic Process

Synonym:	Sertoli cell testicular tumors
SNOMED CT:	Sertoli cell tumor of testis (278057003)

Monarch Initiative:	MONDO:0020808

Definition

A sex cord-stromal tumor that arises from the testis and is characterized by the presence of neoplastic cells with features of Sertoli cells. It usually presents as a slow growing testicular mass. The vast majority of cases follow a benign clinical course. [from NCI]

Term Hierarchy

GTR
MeSH

CClinical test, RResearch test, OOMIM, GGeneReviews, VClinVar

CROGVTesticular sertoli cell tumor

Pathological Conditions, Signs and Symptoms
- Pathological process
  - Disease
    - Neoplasm
      - Testicular sertoli cell tumor
        Benign testicular sertoli cell tumor
        Testicular Sclerosing Sertoli Cell Tumor
        Testicular Sertoli Cell Tumor, Lipid Rich Variant
        Malignant Testicular Sertoli Cell Tumor
        Testicular Large Cell Calcifying Sertoli Cell Tumor

Professional guidelines

PubMed

Clinical Utility of Anti-Mullerian Hormone in Pediatrics.

Kanakatti Shankar R, Dowlut-McElroy T, Dauber A, Gomez-Lobo V
J Clin Endocrinol Metab 2022 Jan 18;107(2):309-323. doi: 10.1210/clinem/dgab687. PMID: 34537849 Free PMC Article

Practices recommendations in the applications of immunohistochemistry and molecular genetics in testicular tumors. Review article.

Michalová K, Michal M, Hora M, Hes O, Michal M
Cesk Patol 2020 Summer;56(3):153-160. PMID: 33076667

Difficult differential diagnoses in testicular pathology.

Ye H, Ulbright TM
Arch Pathol Lab Med 2012 Apr;136(4):435-46. doi: 10.5858/arpa.2011-0475-RA. PMID: 22458906

See all (15)

Recent clinical studies

Etiology

Phenotype evolution and health issues of adults with Beckwith-Wiedemann syndrome.

Gazzin A, Carli D, Sirchia F, Molinatto C, Cardaropoli S, Palumbo G, Zampino G, Ferrero GB, Mussa A
Am J Med Genet A 2019 Sep;179(9):1691-1702. Epub 2019 Jul 24 doi: 10.1002/ajmg.a.61301. PMID: 31339634

Sertoli cell testicular tumors.

Littleton R, Farah R, Cerny J, Ohorodnik J
Urology 1981 Jun;17(6):557-9. doi: 10.1016/0090-4295(81)90075-3. PMID: 7245445

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Diagnosis

The sclerosing sertoli cell tumor of the testis: a case report.

Tang X, Hu Y, Zhou H, Zhou Y
Diagn Pathol 2023 May 15;18(1):61. doi: 10.1186/s13000-023-01351-7. PMID: 37189109 Free PMC Article

Ovarian Sex Cord-stromal Tumors With Melanin Pigment: Report of a Previously Undescribed Phenomenon.

Taylor J, McCluggage WG
Int J Gynecol Pathol 2019 Jan;38(1):92-96. doi: 10.1097/PGP.0000000000000471. PMID: 29140884

Testicular Sertoli cell tumor with a heterologous sarcomatous component: immunohistochemical assessment of Sertoli cell differentiation.

Gilcrease MZ, Delgado R, Albores-Saavedra J
Arch Pathol Lab Med 1998 Oct;122(10):907-11. PMID: 9786352

Metastatic testicular Sertoli-cell tumor: cytopathologic findings on fine-needle aspiration.

Kronz JD, Nicol TL, Rosenthal DL, Ali SZ
Diagn Cytopathol 1998 Aug;19(2):127-30. doi: 10.1002/(sici)1097-0339(199808)19:2<127::aid-dc13>3.0.co;2-h. PMID: 9702492

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