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Hematopoietic and lymphoid cell neoplasm

MedGen UID:
91264
Concept ID:
C0376544
Neoplastic Process
Synonyms: Hematopoietic Malignancies; Hematopoietic Malignancy; Hematopoietic Neoplasm; Hematopoietic Neoplasms; Malignancy, Hematopoietic; Neoplasm, Hematopoietic; Neoplasms, Hematopoietic
SNOMED CT: Malignant hematopoietic neoplasm (414644002); Hematopoietic neoplasm (414388001)
 
Monarch Initiative: MONDO:0044881

Definition

A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVHematopoietic and lymphoid cell neoplasm

Professional guidelines

PubMed

Thompson JA, Schneider BJ, Brahmer J, Achufusi A, Armand P, Berkenstock MK, Bhatia S, Budde LE, Chokshi S, Davies M, Elshoury A, Gesthalter Y, Hegde A, Jain M, Kaffenberger BH, Lechner MG, Li T, Marr A, McGettigan S, McPherson J, Medina T, Mohindra NA, Olszanski AJ, Oluwole O, Patel SP, Patil P, Reddy S, Ryder M, Santomasso B, Shofer S, Sosman JA, Wang Y, Zaha VG, Lyons M, Dwyer M, Hang L
J Natl Compr Canc Netw 2022 Apr;20(4):387-405. doi: 10.6004/jnccn.2022.0020. PMID: 35390769
Brudno JN, Kochenderfer JN
Blood Rev 2019 Mar;34:45-55. Epub 2018 Nov 14 doi: 10.1016/j.blre.2018.11.002. PMID: 30528964Free PMC Article
Brahmer JR, Lacchetti C, Schneider BJ, Atkins MB, Brassil KJ, Caterino JM, Chau I, Ernstoff MS, Gardner JM, Ginex P, Hallmeyer S, Holter Chakrabarty J, Leighl NB, Mammen JS, McDermott DF, Naing A, Nastoupil LJ, Phillips T, Porter LD, Puzanov I, Reichner CA, Santomasso BD, Seigel C, Spira A, Suarez-Almazor ME, Wang Y, Weber JS, Wolchok JD, Thompson JA; National Comprehensive Cancer Network
J Clin Oncol 2018 Jun 10;36(17):1714-1768. Epub 2018 Feb 14 doi: 10.1200/JCO.2017.77.6385. PMID: 29442540Free PMC Article

Recent clinical studies

Etiology

Azanza JR, Mensa J, Barberán J, Vázquez L, Pérez de Oteyza J, Kwon M, Yáñez L, Aguado JM, Cubillo Gracian A, Solano C, Ruiz Camps I, Fortún J, Salavert Lletí M, Gudiol C, Olave Rubio T, Solano C, García-Vidal C, Rovira Tarrats M, Suárez-Lledó Grande M, González-Sierra P, Dueñas Gutiérrez C
Rev Esp Quimioter 2023 Jun;36(3):236-258. Epub 2023 Apr 5 doi: 10.37201/req/013.2023. PMID: 37017117Free PMC Article
Wudhikarn K, Perales MA
Bone Marrow Transplant 2022 Oct;57(10):1477-1488. Epub 2022 Jul 15 doi: 10.1038/s41409-022-01756-w. PMID: 35840746Free PMC Article
Langerbeins P, Hallek M
Blood 2022 Jul 21;140(3):236-252. doi: 10.1182/blood.2021012251. PMID: 35544585Free PMC Article
Durani U, Hogan WJ
Br J Haematol 2020 Feb;188(4):494-500. Epub 2019 Nov 27 doi: 10.1111/bjh.16278. PMID: 31774551
Cordeiro A, Bezerra ED, Hirayama AV, Hill JA, Wu QV, Voutsinas J, Sorror ML, Turtle CJ, Maloney DG, Bar M
Biol Blood Marrow Transplant 2020 Jan;26(1):26-33. Epub 2019 Aug 13 doi: 10.1016/j.bbmt.2019.08.003. PMID: 31419568Free PMC Article

Diagnosis

Rosenquist R, Bernard E, Erkers T, Scott DW, Itzykson R, Rousselot P, Soulier J, Hutchings M, Östling P, Cavelier L, Fioretos T, Smedby KE
J Intern Med 2023 Oct;294(4):413-436. Epub 2023 Aug 7 doi: 10.1111/joim.13697. PMID: 37424223
Sukswai N, Khoury JD
Curr Hematol Malig Rep 2019 Oct;14(5):368-375. doi: 10.1007/s11899-019-00533-9. PMID: 31338668
Abel GA, Klepin HD
Blood 2018 Feb 1;131(5):515-524. Epub 2017 Nov 15 doi: 10.1182/blood-2017-09-746420. PMID: 29141942
Perkins JC, Davis JE
Hematol Oncol Clin North Am 2017 Dec;31(6):xiii-xiv. doi: 10.1016/j.hoc.2017.09.013. PMID: 29078935
Taylor J, Xiao W, Abdel-Wahab O
Blood 2017 Jul 27;130(4):410-423. Epub 2017 Jun 9 doi: 10.1182/blood-2017-02-734541. PMID: 28600336Free PMC Article

Therapy

Wudhikarn K, Perales MA
Bone Marrow Transplant 2022 Oct;57(10):1477-1488. Epub 2022 Jul 15 doi: 10.1038/s41409-022-01756-w. PMID: 35840746Free PMC Article
Biederstädt A, Rezvani K
Int J Hematol 2021 Nov;114(5):554-571. Epub 2021 Aug 28 doi: 10.1007/s12185-021-03209-4. PMID: 34453686Free PMC Article
Knips L, Bergenthal N, Streckmann F, Monsef I, Elter T, Skoetz N
Cochrane Database Syst Rev 2019 Jan 31;1(1):CD009075. doi: 10.1002/14651858.CD009075.pub3. PMID: 30702150Free PMC Article
Freeman CL, Sehn LH
Br J Haematol 2018 Jul;182(1):29-45. Epub 2018 May 9 doi: 10.1111/bjh.15232. PMID: 29741753
Lee SJ, Wolff D, Kitko C, Koreth J, Inamoto Y, Jagasia M, Pidala J, Olivieri A, Martin PJ, Przepiorka D, Pusic I, Dignan F, Mitchell SA, Lawitschka A, Jacobsohn D, Hall AM, Flowers ME, Schultz KR, Vogelsang G, Pavletic S
Biol Blood Marrow Transplant 2015 Jun;21(6):984-99. Epub 2015 Mar 19 doi: 10.1016/j.bbmt.2015.02.025. PMID: 25796139Free PMC Article

Prognosis

Lopez-Candales A, Mathur P, Mounsey JP, Veeraputhiran M
Postgrad Med 2022 Jan;134(1):7-10. Epub 2021 Nov 26 doi: 10.1080/00325481.2021.1995263. PMID: 34664532
Cordeiro A, Bezerra ED, Hirayama AV, Hill JA, Wu QV, Voutsinas J, Sorror ML, Turtle CJ, Maloney DG, Bar M
Biol Blood Marrow Transplant 2020 Jan;26(1):26-33. Epub 2019 Aug 13 doi: 10.1016/j.bbmt.2019.08.003. PMID: 31419568Free PMC Article
Venugopal S, Zhou S, El Jamal SM, Lane AA, Mascarenhas J
Clin Lymphoma Myeloma Leuk 2019 Sep;19(9):545-554. Epub 2019 Jun 13 doi: 10.1016/j.clml.2019.06.002. PMID: 31281107
Azoulay E, Mokart D, Kouatchet A, Demoule A, Lemiale V
Lancet Respir Med 2019 Feb;7(2):173-186. Epub 2018 Dec 7 doi: 10.1016/S2213-2600(18)30345-X. PMID: 30529232Free PMC Article
Bekadja MA, Brahimi M, Osmani S, Yafour N, Krim A, Serradj F, Talhi S, Amani K, Bouhass RA
Hematol Oncol Stem Cell Ther 2017 Dec;10(4):311-314. Epub 2017 Jul 11 doi: 10.1016/j.hemonc.2017.05.019. PMID: 28711452

Clinical prediction guides

Rosenquist R, Bernard E, Erkers T, Scott DW, Itzykson R, Rousselot P, Soulier J, Hutchings M, Östling P, Cavelier L, Fioretos T, Smedby KE
J Intern Med 2023 Oct;294(4):413-436. Epub 2023 Aug 7 doi: 10.1111/joim.13697. PMID: 37424223
Pemmaraju N, Kantarjian H
Clin Adv Hematol Oncol 2023 May;21(5):257-264. PMID: 37145496
Langerbeins P, Hallek M
Blood 2022 Jul 21;140(3):236-252. doi: 10.1182/blood.2021012251. PMID: 35544585Free PMC Article
Durani U, Hogan WJ
Br J Haematol 2020 Feb;188(4):494-500. Epub 2019 Nov 27 doi: 10.1111/bjh.16278. PMID: 31774551
Cordeiro A, Bezerra ED, Hirayama AV, Hill JA, Wu QV, Voutsinas J, Sorror ML, Turtle CJ, Maloney DG, Bar M
Biol Blood Marrow Transplant 2020 Jan;26(1):26-33. Epub 2019 Aug 13 doi: 10.1016/j.bbmt.2019.08.003. PMID: 31419568Free PMC Article

Recent systematic reviews

Zinzi A, Gaio M, Liguori V, Cagnotta C, Paolino D, Paolisso G, Castaldo G, Nicoletti GF, Rossi F, Capuano A, Rafaniello C
Pharmacol Res 2023 Apr;190:106742. Epub 2023 Mar 22 doi: 10.1016/j.phrs.2023.106742. PMID: 36963592
Pasqui DM, Latorraca CDOC, Pacheco RL, Riera R
Eur J Haematol 2022 Dec;109(6):601-618. Epub 2022 Sep 18 doi: 10.1111/ejh.13851. PMID: 36018500
Grant SJ, Grimshaw AA, Silberstein J, Murdaugh D, Wildes TM, Rosko AE, Giri S
Transplant Cell Ther 2022 Jun;28(6):294-302. Epub 2022 Mar 11 doi: 10.1016/j.jtct.2022.03.006. PMID: 35288347Free PMC Article
Jeong W, Keighley C, Wolfe R, Lee WL, Slavin MA, Kong DCM, Chen SC
Clin Microbiol Infect 2019 Jan;25(1):26-34. Epub 2018 Jul 21 doi: 10.1016/j.cmi.2018.07.011. PMID: 30036666
Zaorsky NG, Williams GR, Barta SK, Esnaola NF, Kropf PL, Hayes SB, Meyer JE
Cancer Treat Rev 2017 Feb;53:47-52. Epub 2016 Dec 22 doi: 10.1016/j.ctrv.2016.11.016. PMID: 28063304Free PMC Article

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